Marja Heinonen-Guzejev

University of Helsinki | HY · Department of Public Health

Background Separating with close siblings and leaving the parental home at an early age represents a major life event for an adolescent (reflected by age at separation in a twin pair) and may predispose them to poor mental health. This study aims to examine the association of age at separation and residential mobility on depressive symptoms in late...

Background Depressive symptoms lead to a serious public health burden and are considerably affected by the environment. Land use, describing the urban living environment, influences mental health, but complex relationship assessment is rare. Objective We aimed to examine the complicated association between urban land use and depressive symptoms am...

Background Previous studies show that occupational noise annoyance is associated with depressive symptoms. This study aimed to investigate the association of perceived occupational noise exposure and depressive symptoms in young adulthood and to evaluate whether noise sensitivity mediates or moderates this association. This study was part of Equal-...

The exposome represents the totality of environmental effects, but systematic evaluation between it and depressive symptoms is scant. Here we sought to comprehensively identify the association of the exposome with depressive symptoms in late adolescence and early adulthood and determine genetic and environmental covariances between them. Based on t...

Background: Depressive symptoms lead to a serious public health burden and are considerably affected by the environment. Land use, describing the urban living environment, has an impact on mental health, but complex relationship assessment is rare. Objectives: We aimed to examine the complicated association between urban land use and depressive sym...

The exposome represents the totality of environmental effects, but systematic evaluation between it and depressive symptoms is scant. We sought to comprehensively identify the association of the exposome with depressive symptoms in late adolescence and early adulthood and determine genetic and environmental covariances between them. Based on the po...

We investigated the association between perceived occupational noise exposure and depressive symptoms in young Finnish adults and whether noise sensitivity moderates this association. This study was based on an ongoing longitudinal twin study. We included those who had been working daily (n = 521) or weekly (n = 245) during the past 12 months (mean...

Depression is a heterogeneous mental health problem affecting millions worldwide, but a majority of individuals with depression do not experience relief from initial treatments. Therefore, we need to improve our understanding of the biology of depression. Metabolomic approaches, especially untargeted ones, can suggest new hypotheses for further exp...

Objectives Leaving the parental home at an early age represents a major life event for an adolescent and may predispose them to poor mental health. This study aims to examine the effect of age at separation and residential mobility (from residential records) on depressive symptoms among twins in late adolescence and young adulthood. Age at separati...

Living in the same household exposes family members to shared environments and may be reflected in estimates of shared environment in twin analyses. The age at the separation of cotwins in a twin pair marks the end of such shared exposure, and the age of separation is commonly self-reported in studies. The objective of the study was to summarize th...

Mild Traumatic brain injury (mTBI) is defined as TBI with loss of consciousness for 30 minutes-or-less, coinciding with a disoriented state lasting for less than 24 hours. The perseverance of mTBI-related symptoms is termed as post-concussion syndrome (PCS). One of the commonly listed symptoms of PCS is noise sensitivity (NS). The aim of this study...

Objective: To describe changes in the prevalence and clinical correlates of noise sensitivity (NS) in mild traumatic brain injury (mTBI) across a 12-month period and to determine whether NS at an early stage of recovery has predictive value for later postconcussive symptoms. Setting: A mixed urban and rural region of New Zealand. Participants:...

Background: Sensitivity to noise, or nuisance sounds that interrupt relaxation and task-related activities, has been shown to vary significantly across individuals. The current study sought to uncover predictors of noise sensitivity, focussing on possible social and cultural determinants, including social position, education, ethnicity, gender, an...

Objective: It is possible that tinnitus, hearing loss and insomnia are all linked to oxidative stress. If so, there should be a relationship between insomnia and hearing loss among patients with tinnitus. The aim of this study was to assess the relationship between insomnia and hearing thresholds for patients with tinnitus. Design: This was a retro...

Background Chronic nonspecific symptoms attributed to indoor nonindustrial work environments are common and may cause disability, but the medical nature of this disability is unclear. The aim was to medically characterize the disability manifested by chronic, recurrent symptoms and restrictions to work participation attributed to low-level indoor p...

Background: Hyperacusis is intolerance of certain everyday sounds that causes significant distress and impairment in social, occupational, recreational, and other day-to-day activities. Objective: The aim of this report is to summarize the key findings and conclusions from the Third International Conference on Hyperacusis. Topics covered: The main...

Background: Hyperacusis is intolerance of certain everyday sounds that causes significant distress and impairment in social, occupational, recreational, and other day-to-day activities. Objective: The aim of this report is to summarize the key findings and conclusions from the Third International Conference on Hyperacusis. Topics covered: The...

Noise sensitivity (NS) is currently well described but its etiology has not been sufficiently explained. Noise sensitive individuals are more likely to attend to sound and evaluate it negatively, perceive it as annoying, have stronger emotional reactions to sound and, greater difficulty habituating to sounds. NS describes a vulnerability to negativ...

Recent functional studies suggest that noise sensitivity, a trait describing attitudes towards noise and predicting noise annoyance, is associated with altered processing in the central auditory system. In the present work, we examined whether noise sensitivity could be related to the structural anatomy of auditory and limbic brain areas. Anatomica...

Noise sensitivity (NS) is a common trait. We are still lacking a model for the mechanism of NS. Some studies have suggested psychological origins but there are recent studies addressing the neural mechanism of NS. In our study investigating neuronal sound processing in relation to NS with combined electroencephalography (EEG) and magnetoencephalogr...

Wind turbines produce broadband sound that also includes low frequencies. Sounds below 20 Hz are contractually referred to as infrasound. Infrasound occurs together with audible sound in both natural and built environments. Infrasound is not generally audible at levels occurring typically in the environment. The most usual effects of audible noise...

Noise sensitive individuals are more likely to experience negative emotions from unwanted sounds and they show greater susceptibility to adverse effects of noise on health. Noise sensitivity does not originate from dysfunctions of the peripheral auditory system, and it is thus far unknown whether and how it relates to abnormalities of auditory proc...

Noise sensitivity (NS) may be subsumed by the environmental intolerance approach, characterized by the attribution of several multisystem symptoms to specific environmental exposures. NS increases the reactivity to noise and predicts noise annoyance. In multiple chemical sensitivity, an impairment in smell cognitive abilities with increased smell h...

After intensive, long-term musical training, the auditory system of a musician is specifically tuned to perceive musical sounds. We wished to find out whether a musician's auditory system also develops increased sensitivity to any sound of everyday life, experiencing them as noise. For this purpose, an online survey, including questionnaires on noi...

Some studies indicate that noise sensitivity is explained by negative affect, a dispositional tendency to negatively evaluate situations and the self. Individuals high in such traits may report a greater sensitivity to other sensory stimuli, such as smell, bright light and pain. However, research investigating the relationship between noise sensiti...

Sensitivity to unwanted sounds is common in general and clinical populations. Noise sensitivity refers to physiological and psychological internal states of an individual that increase the degree of reactivity to noise in general. The current study investigated the relationship between the Big Five personality dimensions and noise sensitivity using...

ABSTRACT Noise sensitivity is a common trait which increases the harmful health effects of noise. It has been associated with impaired somatic health, anxiety and poor sleep quality. Self-assessed poor health is a strong predictor of early retirement. This study is based on the Finnish Twin Cohort. Questionnaire data of a sample of 706 Finnish twin...

Meluherkkyys kuvaa herkkyyttä kokea melu ja reagoida siihen. Se lisää melun häiritsevyyttä. Meluherkät ovat muita alttiimpia melun terveysvaikutuksille, kuten unihäiriöille, verenpaineen nousulle ja kognitiivisten toimintojen häiriöille. Meluherkkyydellä ei tarkoita herkkyyttä saada kuulovaurio, eikä se ei ole liittynyt kuulontutkimuksella mitattuu...

Meluherkkyys kuvaa herkkyyttä kokea melu ja reagoida siihen. Se lisää melun häiritsevyyttä. Meluherkät ovat muita alttiimpia melun terveysvaikutuksille, kuten unihäiriöille, verenpaineen nousulle ja kognitiivisten toimintojen häiriöille. Meluherkkyydellä ei tarkoita herkkyyttä saada kuulovaurio, eikä se ei ole liittynyt kuulontutkimuksella mitattuu...

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Noise sensitivity is a common trait which increases the harmful health effects of noise. It has been associated with impaired somatic health, anxiety and poor sleep quality. Self-assessed poor health is a strong predictor of early retirement. This study is based on the Finnish Twin Cohort. Questionnaire data of a sample of 706 Finnish twin individu...

Noise sensitivity is a personality trait covering attitudes to noise in general. Multiple chemical sensitivity (MCS) is the most commonly used label for clinical chemical intolerance. This study aimed to investigate if the Weinstein's Noise Sensitivity Scale and Quick Environmental Exposure and Sensitivity Inventory's (QEESI) Chemical Intolerance S...

ABSTRACT Noise sensitivity has been considered to be a self-perceived indicator of vulnerability to stressors in general. Multiple chemical sensitivity (MCS) has been to some extent accompanied by noise sensitivity. Overlaps have been suggested in the characteristics of noise sensitivity andMCS. The aim of the present study was to investigate if th...

Noise sensitivity increases the degree of reactivity to noise. It may be a part of a more generic sensitivity to environmental stimuli. Multiple chemical sensitivity (MCS) encompasses a wide range of subjective symptoms provoked by exposure to low levels of chemicals. It has to some extent been accompanied by noise sensitivity indicating a moderate...

Abstract Objective: To analyze whether noise sensitivity increases the risk of disability pension (DP). Methods: Questionnaire data of a sample of 706 Finnish twin individuals (age range, 31 to 65 years) with record linkage to information on DP during 16 years of follow-up were analyzed using individual and pairwise Cox proportional hazards model...

Objective: To analyze whether noise sensitivity increases the risk of disability pension (DP). Methods: Questionnaire data of a sample of 706 Finnish twin individuals (age range, 31 to 65 years) with record linkage to information on DP during 16 years of follow-up were analyzed using individual and pairwise Cox proportional hazards models. Resu...

Noise sensitivity is considered to be a self-perceived indicator of vulnerability to stressors in general and not noise alone. Multiple chemical sensitivity (MCS) has to some extent been accompanied by noise sensitivity, indicating a moderate correspondence between them. The aim of this study is to investigate if the Weinstein's Noise Sensitivity S...

Noise sensitivity is considered to be a self-perceived indicator of vulnerability to stressors in general and not noise alone. Multiple chemical sensitivity (MCS) has to some extent been accompanied by noise sensitivity, indicating a moderate correspondence between them. The aim of this study is to investigate if the Weinstein's Noise Sensitivity S...

Noise sensitivity has been considered to be a self-perceived indicator of vulnerability to stressors in general. Multiple chemical sensitivity (MCS) has been to some extent accompanied by noise sensitivity. Overlaps have been suggested in the characteristics of noise sensitivity andMCS. The aim of the present study was to investigate if the Weinste...

The aim of this study was to investigate the association of noise sensitivity with self-reported hearing disability and hearing levels, with consideration of the role of self-reported history of noise exposure and use of hearing protectors. The study is based on the Finnish Twin Cohort. In 1988, a noise questionnaire was sent to 1005 twin pairs, 14...

The study was based on the Finnish Twin Cohort of same-sex twin pairs. In 1988 a questionnaire was sent to twin pairs discordant for hypertension. 1495 individuals (688 men, 807 women) aged 31–88 years replied, including 573 twin pairs. 218 of the subjects lived in the Helsinki Metropolitan Area. Self-reported noise sensitivity, lifetime noise expo...

Noise can be defined as unwanted sound. It may adversely affect the health and well-being of individuals. Noise sensitivity is a personality trait covering attitudes towards noise in general and a predictor of noise annoyance. Noise sensitive individuals are more affected by noise than less sensitive individuals. The determinants and characteristic...

The association of coronary heart and cardiovascular mortality with noise sensitivity was studied. We also investigated how this association is affected by self-reported lifetime noise exposure. In 1988 a case-control study, based on the Finnish Twin Cohort, was carried out to investigate the relationship between noise and hypertension (n=1495). Po...

We investigated the genetic component of noise sensitivity using a twin-study design. The study sample consisted of 573 same-sexed twin pairs from the Finnish Twin Cohort. The 131 monozygotic (MZ) and 442 dizygotic (DZ) twin pairs with an age range of 31 to 88 years replied to a questionnaire on noise and health-related items in 1988. The noise sen...

The authors examined the relationship of noise sensitivity with health status and psychological factors in individuals <70 yr of age in Finland. Subjects (n = 1,355) were selected from a 1988 case-control study, based on the Finnish Twin Cohort, that assessed noise sensitivity, lifetime noise exposure, and hypertension. Other health status and psyc...

Melu on tyypillinen ympäristön stressiteki-jä, jolla on selviä ter-veysvaikutuksia. Melu-herkkyys lisää melun häiritsevyyttä ja se oli tässä tutkimuksessa merkittävä tekijä melun raportoinnissa. Yksilöt, jotka ovat erityisen herkkiä melulle, ovat myös muita alttiimpia melun vaikutuksille. Melun häiritsevyyden ja meluherkkyyden on todettu ennakoivan...

Self-report of noise exposure was compared with the information of noise maps while taking into account measures of self-reported annoyance and noise sensitivity. Self-report data was analyzed for 1495 subjects from the Finnish Twin Cohort who had replied to a questionnaire in 1988. In addition, noise map information was included in analyses of the...

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Self-report of noise exposure was compared with the information on noise maps while taking into account measures of self-reported annoyance and noise sensitivity. Self-report data were analyzed for 1495 subjects participating in a case-control study of hypertension from the Finnish Twin Cohort who had replied to a questionnaire in 1988. In addition...

Huhtikuussa Wienissä pidetty "One Decade after Chernobyl - Summing up the Consequences of the Accident" -konferenssi avattiin minuutin hiljaisuudella, jolla kunnioitettiin Tshernobylin onnettomuuden uhreja. Saksan ympäristöministeri Angela Merkel totesi, että Tshernobylin ydinvoimalaonnettomuuden jälkeen kaikki kysyivät onko ydinvoiman käyttö edell...

Loviisan ydinvoimalan ydinpolttoainejäte on kuljetettu Majakin jälleenkäsittelylaitokseen, joka sijaitsee noin tunnin ajomatkan päässä Tsheljabinskin kaupungista. Suomalainen lääkäriryhmä kävi alueella tutustumassa hälyttäviin tietoihin, joita lehdistössä oli kerrottu alueen väestön terveydentilasta ja sairaanhoidon tasosta. _______________________...