Maritta Jaakkola

Maritta Jaakkola
University of Oulu · Center for Environmental and Respiratory Health Research (CERH)

MD, PhD

About

141
Publications
20,820
Reads
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3,956
Citations
Citations since 2016
51 Research Items
1957 Citations
2016201720182019202020212022050100150200250300
2016201720182019202020212022050100150200250300
2016201720182019202020212022050100150200250300
2016201720182019202020212022050100150200250300

Publications

Publications (141)
Preprint
Background: Previous inconsistent evidence on effects of green space on the development of allergic rhinitis could be explained by the season of exposure. We explored whether the season and timing of exposure to green space play a role in the development of allergic rhinitis during the first 27 years of life. Methods: In a longitudinal study of 256...
Article
Full-text available
We assessed potential relations between indicators of indoor dampness and mold exposures at home and the level of asthma control among adults. The present population-based cross-sectional study, the Northern Finnish Asthma Study (NoFAS), included 1995 adult subjects with bronchial asthma who replied to study questionnaires (response rate: 40.4%). T...
Article
Full-text available
Background Hospital work environment contains various biological and chemical exposures that can affect indoor air quality and have impact on respiratory health of the staff. The objective of this study was to investigate potential effects of occupational exposures on the risk of respiratory symptoms and lung function in hospital work, and to evalu...
Article
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(1) Poor asthma control increases the occurrence of cold weather-related symptoms among adult asthmatics. We assessed whether the subtype of asthma, taking into account the severity of the asthma, plays a role in these symptoms. (2) We conducted a population-based cross-sectional study of 1995 adult asthmatics (response rate 40.4%) living in northe...
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Introduction: Although rhinitis is among the most common diseases worldwide, rhinitis prevalence in the general adult population is unclear and definitions differ widely. Objective: To summarize the literature on rhinitis prevalence in the general adult population and to assess: (1) the prevalence according to different rhinitis definitions over...
Preprint
Full-text available
Background: The hospital work environment contains various biological and chemical exposures that can affect indoor air quality and have impact on respiratory health of the staff. The objective of this study was to investigate potential effects of occupational exposures on the risk of respiratory symptoms and lung function in hospital work, and to...
Article
Full-text available
Background Both tobacco smoking and atopy increase the risk of adult-onset asthma. We studied if there are differences in the effects of smoking on the risks of atopic and non-atopic adult-onset asthma, and if gender modifies these effects. Methods The Finnish Environment and Asthma Study (FEAS) includes 521 incident cases of adult-onset asthma an...
Preprint
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Background: Work environments are potential areas for spreading respiratory infections. We hypothesized that certain occupations increase susceptibility to respiratory infections among adults with asthma. Our objective was to compare the occurrence of respiratory infections among different occupations in adults with newly diagnosed asthma. Methods:...
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Background We hypothesised that occupational exposures differently affect subtypes of adult-onset asthma. Objective We investigated potential relations between occupation and three subtypes of adult asthma, namely atopic asthma, non-atopic asthma and asthma–COPD overlap syndrome (ACOS). Methods This is a population-based case–control study of inc...
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Objective Exposures at hairdressers’ work have been reported to lead to an increased risk of several health outcomes. The present study aimed to investigate the relations between occupational exposures and respiratory symptoms and lung function among hairdressers in Iran. Methods We conducted a cross-sectional study to compare potential respirator...
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We conducted a time-series analysis of the relations between daily levels of allergenic pollen and mortality in the Helsinki Metropolitan Area with 153 378 deaths; 9742 from respiratory and 57 402 from cardiovascular causes. Daily (average) pollen counts of alder, birch, mugwort and grass were measured. In quasi-Poisson regression analysis, abundan...
Article
Objective The objective of this study was to investigate the potential effects of occupational exposures among fruit and vegetable market workers on the occurrence of respiratory symptoms and on the level of lung function parameters. Methods We conducted a cross-sectional study of 140 men working as fruit and vegetable market workers (response rat...
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Full-text available
Background: Previous studies have suggested an increased risk of asthma related to indoor dampness problems, but their role in the etiology of Asthma-COPD Overlap Syndrome has not been studied. We utilized a population-based incident case-control study to assess potential effect of indoor dampness and molds at home and at work on development of AC...
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Introduction: It is important to study potential differences in pollen concentrations between sampling heights because of diverse outdoor and indoor activity of humans (exposure) at different height levels in urban environments. Previous studies have investigated the effect of height on pollen concentrations based on just one or a few sampling poi...
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There is accumulating evidence that prenatal exposure to air pollution disturbs fetal growth and development, but little is known about these effects in cold climates or their season-specific or joint effects. Our objective was to assess independent and joint effects of prenatal exposure to specific air pollutants on the risk of low birth weight (L...
Preprint
Full-text available
There is accumulating evidence that prenatal exposure to air pollution disturbs fetal growth and development, but little is known about these effects in cold climates or their season-specific or joint effects. Our objective was to assess independent and joint effects of prenatal exposure to specific air pollutants on the risk of low birth weight (L...
Article
Background: Previous studies have provided evidence that prenatal exposure to low-level air pollution increases the risk of preterm birth (PTB), but the findings of the effects of short-term exposure have been inconclusive. Moreover, there is little knowledge on potential synergistic effects of different combinations of air pollutants. Objectives...
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Previously those with asthma were often advised to avoid strenuous exercise because of fear for exercise-induced asthmatic reactions, but recent findings suggest many beneficial effects on health related to exercise. We elaborated on the relation between regular exercise and asthma control among adults. This was a population-based cross-sectional N...
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Background Several studies have assessed effects of short-term exposure to pollen on allergic and asthmatic manifestations. The evidence is inconclusive, and no meta-analysis has been published. Objective To synthesise the evidence on the relations between short-term pollen exposure and the risk of allergic and asthmatic manifestations. Methods W...
Article
Introduction: Dental caries and respiratory tract infections are among the most common infectious diseases worldwide and they both are appearing in the respiratory system. However, their relations are still unclear. This study investigated the association of dental caries on the risk of lower respiratory tract infections (LRTI) in young adulthood....
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We conducted a randomized controlled trial to test the hypothesis that a 24-week exercise intervention improves asthma control in adults. Adults with mild or moderate asthma were randomly assigned to either the exercise intervention group (IG) or the reference group (RG). Participants in IG received an individualized exercising program, including a...
Article
Background: There is some evidence that prenatal exposure to low-level air pollution increases the risk of preterm birth (PTB), but little is known about synergistic effects of different pollutants. Objectives: We assessed the independent and joint effects of prenatal exposure to air pollution during the entire duration of pregnancy. Methods:...
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Introduction Smoking increases the risk of asthma and reduces lung function among subjects with and without asthma. We assessed the effects of smoking on lung function reflecting both central and small airways among adults with newly onset asthma. Methods In a population-based study, 521 (response rate 86%) working-aged adults with clinically defi...
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Cold weather affects the respiratory epithelium and induces bronchial hyperresponsiveness. We hypothesized that individuals with allergic rhinitis or/and asthma experience cold weather-related functional disability (FD) and exacerbation of health problems (EH) more commonly than individuals without these. This was a population-based study of 7330 a...
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Little is known about the levels of exposure to grass pollen in urban environments. We assessed the spatio-temporal variation of grass pollen concentrations and the role of urbanity as a determinant of grass pollen exposure in the Helsinki Metropolitan area. We monitored grass pollen concentrations in 2013 at 16 sites during the peak pollen season...
Data
The Helsinki grass pollen data 2013. (XLS)
Article
Our findings highlight the importance of IL-6 in the pathogenesis of asthma and imply that the GG genotype in rs1800797 and/or rs1800795 polymorphism may predispose to the adverse effects of smoking on adult asthma.
Article
Background: According to our systematic literature review, no previous study has assessed potential effects of regular exercise on asthma control among young adults. We hypothesized that regular exercise improves asthma control among young adults. Methods: We studied 162 subjects with current asthma recruited from a population-based cohort study...
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Background Asthma subtyping is a complex new field of study. Usually both etiological and outcome factors of asthma have been used simultaneously for subtyping thus making the interpretation of the results difficult. Identification of subtypes of asthma based on questionnaire data only will be useful for both treatment of asthma and for research. O...
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Early-life respiratory tract infections (RTIs) and dental caries are among the most common infectious diseases worldwide. The relations between early RTIs and development of caries in permanent teeth have not been studied earlier. We assessed childhood RTIs as potential predictors of caries in young adulthood in a 20-year prospective population-bas...
Article
Background: To our knowledge only one previous study has addressed effects of smoking on lung function in adult asthmatics, who may form a susceptible group. We assessed the relations between current, former and life-time cumulative smoking and lung function among adults with new asthma. Methods: In a population-based study 521 (response rate 86%)...
Article
Background: Early-life respiratory tract infections (RTIs) and dental caries are 2 of the most common infectious diseases. RTIs have been suggested to increase the risk of developing caries in childhood, but the relations between early RTIs and development of caries in permanent teeth have not been studied earlier. Aims and objectives: To investig...
Article
Background: Despite the recent developments in physically- and chemically- based analysis of atmospheric particles, no models exist for resolving the spatial variability of pollen concentration at urban scale. Objectives: We developed land use regression (LUR) approach for predicting spatial fine-scale allergenic pollen concentrations in the Helsin...
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Full-text available
Previous studies have provided contradictory evidence on the role of early childhood respiratory infections in the development of asthma and other allergic diseases during childhood. We investigated early-life respiratory infections as predictors of the development of asthma in a 20-year prospective cohort study (the Espoo Cohort Study, 1991–2011)....
Article
Background: IL33 is an important cytokine in the pathogenesis of asthma, and associations of IL33 gene polymorphisms with asthma have been suggested by several genome-wide analyses. However there are no studies regarding the association of IL33 with adult-onset asthma. Objective: To investigate if IL33 single-nucleotide polymorphisms (SNPs) associ...
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Background Family history of asthma and other allergic diseases have been linked to the risk of childhood asthma previously, but little is known about their effect on the age-of-onset and persistency of asthma until young adulthood.Methods We assessed the effect of the family history of asthma and allergic diseases on persistent vs. transient, and...
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One out of five working persons with asthma has work-related respiratory symptoms. When exploring the symptoms of a working-age patient it is essential to survey the job description and working conditions. Early intervention in the factors aggravating the respiratory symptoms will decrease morbidity, maintain working capacity and improve the qualit...
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Irritant-induced asthma is a rare disease, usually being caused by an accidental or other exceptionally strong exposure to substances irritating the respiratory passages. High-dose inhaled corticosteroid medication is immediately started at the emergency call service. If severe exposure is suspected, it is important to monitor the patient at least...
Article
The occurrence of cold temperature-related symptoms has not been investigated previously in young adults, although cold weather may provoke severe symptoms leading to activity limitations, and those with pre-existing respiratory conditions may form a susceptible group. We tested the hypothesis that young adults with asthma and allergic rhinitis exp...
Article
A substantial proportion of the world's population is exposed to indoor dampness-related exposures. Since the 1990s, studies have assessed the relation between indoor dampness and mold and rhinitis, but the evidence has been inconclusive. No previous meta-analysis has been reported on this topic. We conducted a systematic review and meta-analysis o...
Article
Full-text available
Rationale: Identification of the subpopulation especially susceptible to the adverse effects of second-hand smoke exposure (SHS) would be useful for preventive actions and interventions. Objectives: To investigate whether asthmatic heredity indicates susceptibility to the effects of SHS on the risk of adult-onset asthma. Methods: A population-...
Article
Full-text available
Atopic diseases, including allergic rhinitis, allergic dermatitis and asthma, are common diseases with a prevalence of 30-40% worldwide and are thus of great global public health importance. Allergic inflammation may influence the immunity against infections, so atopic individuals could be susceptible to respiratory infections. No previous populati...
Data
Association between specific IgE antibody levels and atopic disease stratified by gender, The Finnish Environment and Asthma Study (FEAS). (DOCX)
Data
The parts of the questionnaire that were used in this study, The Finnish Environment and Asthma Study (FEAS). (DOC)
Data
Risk of respiratory infections in the past 12 months in subjects with atopic disease and those with no atopic disease stratified by gender, The Finnish Environment and Asthma Study (FEAS). (DOCX)
Data
Risk of lower and upper respiratory tract infections (≥1 infection) in the past 12 months according to the levels of specific IgE antibodies stratified by gender, The Finnish Environment and Asthma Study (FEAS). (DOCX)