Marioara Moldovan

Babeş-Bolyai University | UBB · Institute for Research in Chemistry Raluca Ripan

Among the newest trends in dental composites is the use of graphene oxide (GO) nanoparticles to assure better cohesion of the composite and superior properties. Our research used GO to enhance several hydroxyapatite (HA) nanofiller distribution and cohesion in three experimental composites CC, GS, GZ exposed to coffee and red wine staining environm...

This study seeks to understand the effects of new hydrogels based on Oregano® essential oil, Frankincense® essential oil, and the Thieves® blend, which includes clove, lemon, cinnamon bark, eucalyptus radiata, rosemary extract, and Frankincense® essential oil through in vitro cytotoxicity and antimicrobial analysis. Mesenchymal stem cells (D1MSCs)...

The study evaluated the impact of graphene powders used as additives in the recipe of the experimental lime mortar to a mixture ratio of 1:2.5 of NHL3.5 hydraulic lime:fine sand. The content of binder, aggregate and water was kept constant, varying only the amount and the type of the added additives in relation to the amount of natural hydraulic li...

Brackets are metallic dental devices that are very often associated with acidic soft drinks such as cola and energy drinks. Acid erosion may affect the bonding between brackets and the enamel surface. The purpose of this study was to investigate the characteristics of brackets’ adhesion, in the presence of two different commercially available drink...

This paper investigates the nutraceutical properties of the whey Zonar and of lyophilized concentrate obtained from Zonar in C26 tumor bearing BALB/C mice. The experiment was conducted on 30 female mice, divided into 6 groups (n=5). Groups 4, 5 and 6 were injected subcutaneously with 1*106 C26 carcinoma cells. Groups 2,3, 5 and 6 received a diet ba...

The present research is focused on three different classes of orthodontic cements: resin composites (e.g., BracePaste); resin-modified glass ionomer RMGIC (e.g., Fuji Ortho) and resin cement (e.g., Transbond). Their mechanical properties such as compressive strength, diametral tensile strength and flexural strength were correlated with the samples’...

Objectives: The current study aimed to compare the efficacy of two in vitro microbiological models based on open and closed systems designed to obtain secondary caries in an accelerated and reproducible way. Methods: A conventional resin-based composite (RBC - Majesty ES-2; Kuraray, Japan) and a resin-modified glass-ionomer cement (RMGIC - Ionol...

One of the recent trends in the development of resin-based composites (RBCs) focuses on universal coloring to avoid time-consuming color matching and RBC layering for a clinically appropriate esthetic impact. We evaluated an experimental material for posterior restorations combining universal coloring with the possibility of bulk-fill placement. Cl...

The enamel white spot lesion is a common complication of orthodontic treatment with a high prevalence. This research aims to create an artificially induced white spot lesion, evaluate three different commercial products in terms of visual appeal, mineral reestablishment, and roughness, and determine which material can recover the initial structure....

Poor oral hygiene leads to serious damages of theteeth’s surface enamel such as micro-abrasions and acid erosion. These alterations combined with bacterial plaque result in cavity appearance. Prophylactic measures include various techniques for enamel surface restoration. Fluorination is one of the most important treatments for this purpose. Theref...

Functionalized graphene and hydroxyapatite fillers are proposed as reinforcing particles in light-cured adhesives for dental applications. Silica-silver-graphene (SiO2-Ag-Gr), silver-doped hydroxyapatite (HA-Ag), graphene and silver doped hydroxyapatite (HA-Ag-Gr), and regular silica (SiO2) as inorganic powders, together with bis-GMA (2,2-bis[4-(2-...

In this experimental study, the mechanical and adhesion properties of several hydraulic lime mortars incorporating graphene oxide (GO)-based nanomaterials were evaluated. Four different composite mortar samples were prepared by adding different percentages of GO-based powders (functionalized), i.e., 1 wt.% GO, 5 wt.% GO, 5wt.% GO-Ag-GO-Fly ash, and...

By-products from the meat and dairy industries are important sources of high biological value proteins. This paper explores possibilities for improving the swelling and integrity of a cross-linked whey and gelatin hydrogel with different amounts of CuSO4 × 5H2O. Overall, swelling tests demonstrate that cross-linked samples show a better hydration c...

This study aims to investigate the effect of new natural photosensitizers (PS) (based on oregano essential oil, curcuma extract, and arnica oil) through in vitro cytotoxicity and biological tests in rat-induced periodontal disease, treated with photodynamic therapy (aPDT). The cytotoxicity of PS was performed on human dental pulp mesenchymal stem c...

Background: The aim of this in vitro study was to assess the morphological characteristics and stability of dental composites immersed in saliva collected from patients with leukemia. Material and Methods: A total number of five patients without systemic disease and 20 patients with leukemia (acute lymphoblastic leukemia (ALL), acute myeloid leukem...

The aim of the present study was to obtain experimental infiltration materials, intended for the treatment of dental white spots, and to investigate them. Two series of infiltrants (P1–P6)/(P1F–P6F) were obtained, based on different monomer mixtures, without/with glass filler (with fluoride release ability). Each infiltrant from the second series c...

The use of PDT in prosthodontics as a disinfection protocol can eradicate bacteria from tooth surfaces by causing the death of the microorganisms to which the photosensitizer binds, absorbing the energy of laser light during irradiation. The aim of the study was to investigate the capacity of PDT to increase the bond strength of full ceramic restor...

(1) Background: This study investigated the influence of Bis-GMA, TEGDMA, UDMA, and two different polyethylene glycol (PEG)-containing, UDMO-based co-monomers on the Young’s modulus and flexural strength, degree of methacrylate C=C double bond conversion and residual monomer elution of experimental dental resins. (2) Methods: Urethane methacrylate-...

Various powders of graphene oxide (GO), GO with silver (GO-Ag) and zinc oxide (GO-ZnO) were obtained. The powders were silanized with (3-aminopropyl) triethoxysilane (APTES) aiming to be used, in a future stage, as additives in the hydraulic lime mortars composition. The powders were characterized by Fourier Transform Infrared Spectrometry (FTIR) a...

Background: The aim was to analyze, in vitro, four resin based composite systems (RBCs) immersed in saliva of leukemia patients before starting chemotherapy regiments. Material and methods: Saliva was collected from 20 patients (4 healthy patients, 16 leukemia patients). Resin disks were made for each RBC and were immersed in the acute leukemia...

The growing interest in the appearance and color of teeth has led to the emergence of a wide range of teeth whitening methods, both in dental offices and in patients’ homes. Concerns about the possible side effects or toxic effects of peroxide-based whitening gels leads to the identification of alternative whitening methods, based on natural compou...

The orthodontic miniscrew (TADs) is a device that is fixed into bone in the short term for the purpose of enhancing orthodontic anchorage. The aim of our study was to investigate the structural and surface properties of recovered TADs after orthodontic treatment, and compare them to new TADs. TADs (n = 15) from the same manufacturer (Absoanchor; De...

Statement of problem: The selective laser melting (SLM) process has become popular for the fabrication of frameworks for metal-ceramic restorations, although their surface roughness is greater than with cast or milled frameworks. Limited information is available regarding the surface mechanical characteristics of cobalt-chromium (Co-Cr) SLM-manufac...

The purpose of modern dental medicine is to prevent dental caries and promote minimally invasive techniques at the expense of invasive methods. Dental sealants are largely recommended for occlusal surfaces protection, but concerns are related about microleakage at material-enamel interface. This in vitro study aimed to investigate the association b...

In the last two decades, both general and oral health status became more important for individuals, being associated to their quality of life, social provenance and income. Society�s evolution is associated to high expectations regarding edentulous and decays treatment. Metal filling such as gaudent or amalgam have been replaced by aesthetic materi...

The aim of this study was to evaluate the correlation between the percent of inorganic filler by weight (wt. %) and by volume (vol. %) of 11 flowable resin composites (FRCs) and their mechanical properties. To establish the correlation, the quantity of inorganic filler was determined by combustion and shape/size analyzed by SEM images. The compress...

Chronic kidney disease (CKD) represents a progressing and life-threatening pathology which produces a series of changes in the bio humoral parameters. Some of the changes that develop in CKD includes modified levels of minerals and trace elements such as iron, nickel, selenium, magnesium, zinc, copper, aluminium. In a proper concentration, those ar...

Microorganisms, such as bacteria, fungi, archaea and cyanobacteria, are capable of colonizing on surfaces of a wide range of materials and could cause the biodeterioration of these, particularly the walls of historical buildings exposed to changing environmental conditions, such as temperature, relative humidity, pH and sunlight. The deterioration...

The presence of nitrite and nitrate in milk and dairy products may cause serious health problem for consumers. Thus, a simple and accurate ion-pair reversed-phase high performance liquid chromatographic (IP-RP-HPLC) method has been developed and validated for determination of nitrite and nitrate in some dairy drinks based on Zonar Milk Serum. The s...

In this study, the radiopacity of chairside Computer-Aided Design-Computer-Aided Manufacturing (CAD-CAM) milling materials was evaluated in comparison with dental structures. 105 specimens of 7 different thicknesses from 5 different types of chairside CAD-CAM milling materials: feldspar ceramic, hybrid ceramic, lithium disilicate glass-ceramic, zir...

It is well-known that the most frequent cause of the degradation of heritage buildings is related to the presence of water because all the traditional materials used, are more or less porous and constitute the support of water migration in the form of salt solutions. In order to establish the technological solution for control humidity, it is extre...

The influence of silanised silica fume addition on the pore size distribution and wettability of white cement paste was investigated using T1–T2 correlation nuclear magnetic resonance (NMR) relaxometry. Surface silanisation of silica fume particles was achieved by the hydrolysis reaction of APTES (3-Aminopropyltriethoxysilane) and condensation of t...

Polylactic acid (PLA) synthesis has driven considerable interest in tissue engineering, as well as in medicine, food and pharmaceutical industry. PLA is used as a biomaterial in various medical applications, such as tissue engineering, orthopedic devices and drug delivery systems. The main goal of this review is to highlight the PLA development and...

ABSTRACT. The main purpose of this research is in vitro biocompatibility testing of a polylactic acid polymer (PLA) synthesized by the condensation of lactic acid separated from whey (Zonar). The experimental PLA obtained was characterized by: Scanning Electron Microscopy which pointed a homogeneous microstructure of the polymer without a separatio...

The objective of this in-vitro study was to compare the accuracy, defined as trueness and precision, of two intraoral digital scanners that use different capturing techniques. An experimental reference object consisting of a die was manufactured from a PMMA resin. The reference object was digitized with an industrial CT and was scanned 15 times wit...

Silicate-based biomaterials play an important role in formulations applied in medicine. Graphene oxide-SiO2 (GO-SiO2) and reduced graphene oxide-SiO2 (rGO-SiO2) composites were prepared by a two-step (chemical and thermal) method. Hydroxyapatite-SiO2 (HA-SiO2) and thermally treated (900 °C) hydroxyapatite-SiO2 (tHA-SiO2) composites were obtained by...

The hydrodesulphurization (HDS) of thiophenes was performed on metallic catalyst CoMoRe/ZSM5-γAl2O3. Experiments were carried out on a fixed bed catalytic reactor at 175-300°C, 30-60 atm, thiophene volume hourly space velocities of 1h⁻¹- 4h⁻¹ and molar ratio hydrogen/thiophene of 60/1. Texture features like specific surface area, the pore volume an...

Cellular adhesion on surface structures from PA 2200 made through Selective Laser Sintering (SLS) process can be improved by modifying the parts surface. In this paper, different methods for surface modification are presented. The PA 2200 samples were immersed in six different solvents. SEM images and surface roughness tests were performed in order...

Background: Normal or inflamed gingival tissues are regarded as a source of mesenchymal stem cells (MSCs) abundant and easily accessible through minimally invasive dental procedures. Due to the proximity of dental resin composites to gingival tissues and to the possible local cytotoxic effect of the eluted components, gingiva-derived MSCs could be...

The objective of this in-vitro study was to compare if there are any differences in the marginal fit of crowns fabricated by CAD/CAM technique. We used three different types of materials (two types of polymethylmetacrylate (PMMA) provided by two different manufacturers and one type of hybrid ceramic) and three different types of impressions: intrao...

Graphene/TiO2-Ag based composites having various quantities of TiO2-Ag nanoparticles (5, 10 or 15 wt%) were successfully prepared through a facile chemical-thermal route. The morphological and structural characteristics of the synthesized materials denoted GTA-5, GTA-10 and GTA-15 were investigated by TEM, XRD and FTIR techniques. The composites we...

Dairy beverages are ideal for adding value in terms of nutrition and functional additives. Four new dairy beverages derived from lactoserum are characterised in the present study, as by determination of physicochemical parameters and chemical composition: pH, titratable acidity, total dry matter, sodium chloride, lactose, total proteins, and the mi...

The aim of this paper was to determine the minerals and lactose from a Zonar lactoserum concentrate (L-ZS) obtained by lyophilization as compared to other two commercial powders: a bio whey concentrate (BWP) and a whey protein isolate (IWP), in order to investigate the influence of the mineral and lactose concentration on the protein denaturation t...

New precursors for functionalized grass fibres were obtained through deposition of functionalized calix[4]arenes on G14 short glass fibers. The methods employed for the preparation as well as the characterization by thermal analysis, FT-IR spectroscopy, TEM and SEM microscopy of the newly obtained materials is presented. © 2017, Universitatea Babes...

Graphene nanosheets (EGr) were electrochemically prepared through one-step exfoliation of graphite rod in a mixture of H2SO4:HNO3 (3:1) at low bias (4 V). Subsequently, gold nanoparticles were attached to graphene surface (EGr-Au) by the reduction of the metal precursor (HAuCl4) in aqueous solution containing dispersed graphene sheets. According to...

A major problem in laser beam melting is to post-process the complex surfaces. The objective of this research was to investigate the influence of three combined post-processing methods on customized implants manufactured b y selective laser melting, focusing on complex contact surfaces between the parts and support structures. These anatomical cont...

The aims of our study were to assess the cytotoxic effect of five orthodontic bonding materials, in vitro, on HUVECs to study the induction of apoptosis and inflammatory response generated to assess the shear-bond strength of the 5 tested materials in order to quantify their performance. Standardized samples from each material were obtained and inc...

The development of Additive Manufacturing technologies has led to the direct production of complex implants, eliminating shape or structure restrictions, and having mechanical properties that meet the requirements of medical standards. This chapter describes the concept of implants with macro-porous structures and its production technologies. Furth...

Polyethylene terephthalate (PET) based nanocomposites containing nano-silica (Aerosil (Degusa)) and titanium oxide (TiO2 (Merk)) were prepared by melt compounding. Influence of nano-silica and titanium oxide on properties of the resulting nanocomposites was investigated by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy...

Dental erosion is a frequent complication of patients with gastro-esophageal reflux disease. Loss of superficial enamel can be observed by a color change towards yellow and increased translucency of the teeth. The aim of our study was to analyze salivary parameters and dental erosion status in patients with gastro-esophageal reflux disease, and to...

The aim of this study is to evaluate teeth discoloration after the usage of adhesive fluoride release. Material and Method: 80 extracted healthy premolars divided into two groups were used in the study, with metal brackets being bonded in both groups,. The first group universal adhesive was applied (transbond light cure adhesive paste-Transbond XT)...

In this study urethane dimethacrylate (UDMA) based dental resin materials were synthesized. Urethane methacrylate oligomers (UDMO) were synthesized via a radical chain growth polymerization mechanism using polyethylene glycol (PEG) in order to improve the mechanical properties, without adding a solvent in the reaction medium. The structure of the n...

The aim of this study was to investigate the interface ultrastructure at dentin and hybrid layer formed by novel adhesives with TiO2 nano-fillers. Nano-fillers have shown outstanding mechanical properties and they are widely used as reinforcing materials associated with polymeric matrices for high performance applications. Twenty extracted non cari...

The present study reports the analytical approaches for characterization of teeth whitening gels based on natural extracts of fruits and medicinal plant. High performance liquid chromatography (HPLC) with UV detection were used for identification and quantification of (oxalic, citric, tartaric, malic, succinic and fumaric acids), flavonoids (catech...

Background Allium species extracts including Allium cepa L. contain sulfur compounds, known for their antiplatelet, antimicrobial, antineoplasic activities. Methodology Antibacterial activity of a formulation based on A . cepa extracts-liquid and lyophilized samples, has been demonstrated using two classes of bacteria: Gram-positive ( Staphylococc...

Photodynamic therapy (PDT) also known as Phototherapy or Photo chemotherapy involves the use of a photoactive dye (photosensitive) which is activated by exposure to light of a certain wavelength in the presence of oxygen. Dentists have to deal regularly with oral infections which untreated may cause systemic infections. Oral infections such as cari...

Objectives Tooth bleaching is one of the most required dental esthetic treatments. However, it can generate side effects like oral irritation, enamel alteration, tooth sensitivity, especially caused by hydrogen peroxide, the main bleaching component of the commercial products. Therefore, development of new tooth bleaching agents, based on natural p...

Curcumin, a natural phenolic compound is an anti-tumor agent with anti-inflammatory and anti-oxidant properties. The aim of this research was to evaluate oxidative stress levels, the antioxidant activity and Curcumin concentrations by high performance liquid chromatography (HPLC) in an acute experimental inflammation induced by Turpentine oil (intr...