Mario Speranza

Mario Speranza
INSERM University Paris-Saclay University of Versailles

Professor of Child and Adolescent Psychiatry

About

173
Publications
101,878
Reads
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2,992
Citations
Citations since 2016
59 Research Items
1708 Citations
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Introduction
A major focus of my clinical and research activity is the study of emerging personality disorders in children and adolescents, especially borderline personality disorders, using a developmental framework. I’ve been especially interested in the development and disruption of emotion regulation, using both a quantitative and qualitative approach. A second thread of my research is concerned with the evaluation of the effectiveness of mental health organizations for severe mental disorders.
Additional affiliations
March 2007 - March 2012
Paris Descartes, CPSC
Position
  • Researcher
September 2003 - present
Centre Hospitalier de Versailles
Position
  • Head of the Child and Adolescent Department
September 2003 - present
Université de Versailles Saint-Quentin
Position
  • Professor (Full)

Publications

Publications (173)
Article
Background While adult outcome in autism spectrum disorder (ASD) is generally measured using socially valued roles, it could also be understood in terms of aspects related to health status – an approach that could inform on potential gender differences. Methods We investigated gender differences in two aspects of outcome related to health-status,...
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Background: Despite the importance of the parents’ role in socializing children, there is no specific tool in this field in Iran. The Coping with Children’s Negative Emotions Scale (CCNES) is a tool to assess the parents’ responses to children’s emotions. Objectives: This study evaluated the reliability and factor structure of a Persian version of...
Article
Résumé Objectifs Étudier l’état des connaissances et des représentations au sujet du trouble de personnalité borderline d’un groupe de soignants francophones intéressés par ces patients. Méthodes Entre 2019 et 2020, nous avons au début d’une formation aux approches psychothérapeutiques du trouble de personnalité borderline fait passer à 126 soign...
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Objectives: While long-lasting antipsychotics (LLA) were specifically developed to address the problem of adherence in patients with chronic psychiatric disorders, their role in pediatric populations is not clear. Methods: To document the efficacy, tolerance, and acceptance of LLAs in children and adolescents, a literature search was conducted usin...
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PurposeTo compare mothers and fathers perceptions of the impact of autism spectrum disorder on their Quality of Life (QoL), we used the Parental-Developmental Disorders-Quality of Life scale (Par-DD-QoL).Method The perception of QoL of mothers and fathers was compared for 130 pairs of parents of children with ASD and the associated variables were i...
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Purpose The service configuration with distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) may be a barrier to continuity of care. Because of a lack of transition policy, CAMHS clinicians have to decide whether and when a young person should transition to AMHS. This study describes which characterist...
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Background Literature data about emotion perception in patients with borderline personality disorders (BPD) revealed some discrepancies between some patients that are vigilant and accurate to detect their emotional environment and others that are impaired at identifying emotions of others. Even if some links between childhood adversity and facial a...
Article
Lay abstract: Sensory atypicalities are very common among autistic people and are integrated in several theories and explanatory models of autism. Qualitative studies have explored these singular sensory experiences from the perspectives of autistic people themselves. This article gathers all these qualitative studies and provides original finding...
Preprint
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Previous work has shown that various dimensions of early life adverse experiences, such as deprivation, threat and unpredictability are associated with both physical and mental health outcomes throughout the life course. However, the concepts and operationalisations of unpredictability vary greatly across studies. In this study, we explored how dif...
Article
Résumé Le trouble déficit de l’attention avec ou sans hyperactivité est un trouble neurodéveloppemental marqué par une forte hétérogénéité des profils cognitifs et comportementaux des enfants atteints. Une altération des capacités de mémoire de travail est très souvent retrouvée. Cette atteinte touchant de manière privilégiée l’administrateur centr...
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Autism spectrum disorder (ASD) has a significant impact on the quality of life (QoL) of families. This study aimed to examine, for parents of children with ASD, the dyadic effect of each parent’s coping strategy on the perception of the impact of ASD on their QoL. In total, 164 couples completed self-report questionnaires, including the Par-DD-QoL,...
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Inclusion of students with Autism Spectrum Disorder (ASD) in mainstream schools has a positive impact on their social and daily living behaviors. Our objective was to identify clinical and socio-demographic variables promoting or limiting inclusion in mainstream school through childhood and adolescence. The EpiTED study is a long-term, prospective,...
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Background: Psychopathological models of adolescent borderline personality disorder (BPD) suggest that non-suicidal self-injuring (NSSI)—a particularly frequent symptom in girls—may constitute a way of coping with distress resulting from interpersonal concerns they typically experience as a developmental psychopathological feature. Objectives: Our...
Article
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Introduction: Borderline personality disorder (BPD) in adolescents is characterized by emotional dysregulation, insecure attachment, a history of stressful life events (SLEs) as well as dysfunctional parent–child interactions. The respective contribution of each of these factors on BPD affective symptoms is not yet clear. The purpose of this study...
Article
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Background Emotional dysregulation seems to be a core feature of Borderline Personality Disorders (BPD). In addition, recent research in the adolescent population has shown that suicidal behaviours have been associated with maladaptive strategies of emotion regulation. Methods This study examined the relative contributions of emotional dysregulati...
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Résumé La recherche scientifique a mis en évidence l’importance d’adopter une approche développementale et interactionnelle pour comprendre la complexité du fonctionnement psychique de l’être humain. Ces dernières années un intérêt particulier a été porté par la psychologie du développement à l’étude de l’émergence des compétences cognitives et émo...
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Background Training in psychiatry requires specific knowledge, attitudes, and skills that are obtainable by simulation, of which the use is only recent and still needs further development. Evidence is accumulating on its effectiveness but requires further validation for medical students. We aimed to evaluate the effectiveness of a single-day option...
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Within the European Research Network on BPD (EURNET-BPD; n = 85 BPD adolescents, n = 84 healthy controls, aged 13–19), this study explored the combination of three types of adversity—maltreatment, stressful life events (early separation from parents, parental suicide attempt, parental chronic disease) and parental bonding—as predictors of BPD, on a...
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Introduction Intervention in the preschool period is currently recommended for autism spectrum disorder. Therapies delivered by parents are particularly suitable for young children. Preschool Autism Communication Trial (PACT) is a parent-mediated therapy that has shown a significant and sustained impact on autism symptom reduction. However, access...
Preprint
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Background: Training in psychiatry requires specific knowledge, attitudes, and skills that are obtainable by simulation, which needs further development for medical students. After an analysis of previous research with medical students, we evaluated the effectiveness of a one-day teaching program in psychiatry by simulation and validated a scale me...
Article
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TEDIS, an information system dedicated to patients affected with neuro-developmental disorders including autism, focuses on patient data generated during in-depth clinical assessment in nine expert centers in Ile-de-France region. Long term partnership involving methodologists and domain experts is necessary to support quality data production and a...
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Résumé Objectifs Le confinement général de la population française dans le contexte de la pandémie de COVID-19, liée au nouveau Coronavirus SARS-COV-2, est une situation potentiellement à risque pour les enfants avec un développement atypique. L’objectif de notre étude est de mieux comprendre l’état de santé mentale des enfants et adolescents avec...
Article
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Background: The study examines the psychometric properties of the French version of the McLean Screening Instrument for Borderline Personality Disorder (MSI-BPD) created by M. Zanarini to screen borderline personality disorder in clinical and non-clinical populations. Method: In this multicentric longitudinal study from the European Network on B...
Article
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Innovations in child psychotherapy. The psychotherapeutic approach represents the main focus of care in the field of child and adolescent mental health because of the limited place of psychopharmacology at this period of life. In recent years we have witnessed a diversification of theoretical models and the development of new focused approaches whi...
Preprint
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Background The study examines the psychometric properties of the French version of the McLean Screening Instrument for Borderline Personality Disorder (MSI-BPD) created by M. Zanarini to screen borderline personality disorder in clinical and non-clinical populations. Method In this multicentric longitudinal study from the European Network on Border...
Preprint
Full-text available
Background: The study examines the psychometric properties of the French version of the McLean Screening Instrument for Borderline Personality Disorder (MSI-BPD) created by M. Zanarini to screen borderline personality disorder in clinical and non-clinical populations. Method: In this multicentric longitudinal study from the European Network on Bord...
Article
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INTRODUCTION: Since 2011, the French government estimates that about 500 French children were born or were taken by their parents to areas where terrorist operations prevail. Since May 2017, 75 children who returned to France have benefited from a specific health care system. METHOD: This article is the result of clinical interviews conducted with...
Article
Le diagnostic précoce des troubles de la communication sociale de l’enfant, avant l’âge de 24 mois est un enjeu majeur de santé publique. L’objectif de cette communication est de faire un état des lieux des connaissances, quant aux nouvelles stratégies diagnostiques et thérapeutiques aux plus jeunes âges de la trajectoire de développement. (1) V. V...
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Background: Inhibitory control, a key modulatory component of cognition guiding strategy and behaviour, can be affected by diverse contingencies. We explore here the effect of expectation of reward over behavioural adjustment in a Stop Signal Task modulated by reward. We hypothesize that cognitive control is modulated by different expectation of t...
Article
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Introduction: Adolescence is a critical period for the development of mentalizing - the imaginative capacity to understand one's own and others' behaviour in terms of underlying mental states. Yet, factors and mechanisms underlying individual differences in adolescent mentalizing remain poorly understood. This exploratory study examined whether an...
Article
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Introduction There is global concern about the increasing prevalence of autism spectrum disorders (ASDs), which are early-onset and long-lasting disorders. Although ASDs are considered to comprise a unique syndrome, their clinical presentation and outcome vary widely. Large-scale and long-term cohort studies of well-phenotyped samples are needed to...
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Introduction: Experiencing adverse life events and early disturbed patterns of interaction are crucial determinants for the development of Borderline Personality Disorder (BPD). Parental suicidal attempts can be considered a major adverse life event and a potentially traumatic experience. The aim of this study was to examine differences in parental...
Article
La Thérapie Basée sur la Mentalisation (TBM) est une forme d’intervention psychothérapeutique manualisée et empiriquement validée qui intègre des dimensions issues de la théorie de l’attachement, de la psychologie développementale et des neurosciences cognitives (Bateman & Fonagy, 2016). Le terme de mentalisation fait référence à une forme d’activi...
Article
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Several researchers point to disorganized attachment as a core feature of borderline personality disorder (BPD). However, recent studies suggest that specific internal working models (IWMs) of each parent combine to account for child outcomes and that a secure relationship with one parent can protect against the deleterious effects of an insecure r...
Article
Background: Autism is a neurodevelopmental disorder with various clinical presentations. It has been historically considered a male disorder. An increasing number of authors stress the existence of sex/gender bias in prevalence and the need to define sex/gender differences in the clinical presentation. Review: Recently, an increasing number of a...
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We emphasize the value of a developmental framework for adolescent diagnosis and clinical formulation. Clinical use of diagnostic approaches constructed for either children or adults risks misunderstanding, and perhaps even misdiagnosing, symptoms and experiences that may be tied to the psychological, social, and biological changes inherent in this...
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Psychological well-being and mental health among intellectually gifted children and adolescents is a questioning issue for many professionals in psychology, clinical psychopathology, education, and often for young people themselves and their families. We present here a synthesis on the subject, with a distinctin between quantitative psychology, dim...
Article
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Background: Telemedicine for children and adolescents is a public health topic, and since 2009 in France, the legal framework defines practical modalities. Some children with Attention Deficit with or without Hyperactivity Disorder, social anxiety, or Autism Spectrum Disorder (ASD) can be easily engaged within a teleconsultation model. Literature...
Preprint
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In order to address the question of the adaptive changes in executive inhibition induced by expectation, we designed a stop signal task where participants either knew or ignored the possibility of receiving distinct monetary feedbacks after each successful inhibition. Our results confirmed previous observations demonstrating a “kick start effect”:...
Conference Paper
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Longitudinal data point to disorganized attachment toward the mother as a risk factor in the development of borderline personality disorder (BPD). However, several authors posit that the deleterious effects of an insecure relationship with the mother can be moderated by a secure relationship with the father. A few studies do suggest that internal w...
Article
Autism Spectrum Disorder (ASD) is a frequent neurodevelopmental disorder. ASD is probably the result of intricate interactions between genes and environment altering progressively the development of brain structures and functions. Circadian rhythms are a complex intrinsic timing system composed of almost as many clocks as there are body cells. They...
Article
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Introduction Early intervention for autism spectrum disorder (ASD) in the European French-speaking countries is heterogeneous and poorly evaluated to date. Early intervention units applying the Early Start Denver Model (ESDM) for toddlers and young children with ASD have been created in France and Belgium to improve this situation. It is essential...
Article
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Cet article propose une synthèse des principales données expérimentales à propos des capacités sociocognitives des adolescents, obtenues sur le plan comportemental et cérébral. Il se cible sur un ensemble de concepts voisins de la mentalisation (théorie de l’esprit, empathie, traitement des visages et des aspects liés à soi) qui ont l’avantage de p...
Article
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Borderline personality disorder (BPD) has onset in adolescence, but is typically first diagnosed in young adulthood. This paper provides a narrative review of the current evidence on diagnosis, comorbidity, phenomenology and treatment of BPD in adolescence. Instruments available for diagnosis are reviewed and their strengths and limitations discuss...
Article
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Borderline personality disorder (BPD) has onset in adolescence, but is typically first diagnosed in young adulthood. This paper provides a narrative review of the current evidence on diagnosis, comorbidity, phenomenology and treatment of BPD in adolescence. Instruments available for diagnosis are reviewed and their strengths and limitations discuss...
Article
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Les psychoses sont sans doute la préoccupation constante des psychiatres d'adolescents qui craignent avant tout l'entrée dans la schizophrénie qu'ils sont conduits à évoquer devant des symptômes très divers venant exprimer de façon polymorphe la souffrance psychique fréquente à cet âge. En effet, l'adolescence, qui est un moment de profondes mutati...
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The aim of this paper is to discuss the psychological factors involved in the process of learning and especially to conceptualize the impact of cognitive disorders on the emotional development and the learning identity of the child. Several recent epidemiological studies have shown, in children with learning disorders, an increased risk of psychopa...
Article
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It is common that intellectually gifted children (IQ ≥ 130) are referred to paediatric or child neuropsychiatry clinics for socio-emotional problems and/or school underachievement or maladjustment. Among them, those displaying developmental asynchrony - a heterogeneous developmental pattern reflected in a significant verbal-performance discrepancy...
Article
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There is a growing interest in the role of biological and behavioral rhythms in typical and atypical development. Recent studies in cognitive and developmental psychology have highlighted the importance of rhythmicity and synchrony of motor, emotional, and interpersonal rhythms in early development of social communication. The synchronization of rh...
Article
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Objective: High and low body mass index (BMI) values and inaccurate body weight perceptions (BWP) (i.e.: mismatch between BMI and BWP) are known risk factors for depression/suicide. However, the relationships between BMI, BWP and depression are still insufficiently understood in adolescents, and data are lacking concerning the entire range of BMI i...
Article
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Objectives The main objective of this study was to estimate the prevalence of psychological distress among adolescents seen in emergency departments, and the secondary objective was to highlight their main reasons for consulting. Methods Cross-sectional study in three multicenter emergency departments receiving adolescents in Île-de-France conduct...
Article
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The ability to override a dominant response, often referred to as behavioural inhibiton, is considered a key element of executive cognition. Poor behavioural inhibition is a defining characteristic of several neurological and psychiatric populations. Recently, there has been increasing interest in the motivational dimension of behavioural inhibitio...
Article
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The main objective of this study was to estimate the prevalence of psychological distress among adolescents seen in emergency departments, and the secondary objective was to highlight their main reasons for consulting. Cross-sectional study in three multicenter emergency departments receiving adolescents in Île-de-France conducted in 2010. All adol...