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Introduction
Mario Coutinho currently works at the Clinical Medicine Department, Federal University of Santa Catarina, Florianopolis, Brazil. Mario does research in Cardiology, Intensive Care Medicine, Clinical Epidemiology and Internal Medicine (General Medicine). Their current project is 'Risk factors for cardiovascular disease in children and adolescents in south Brazil.'.
Current institution
Additional affiliations
Education
June 1987 - July 1990
Publications
Publications (50)
Brazilian Guidelines for Acute Myocardial Infarction with ST-segment Elevation Treatment
Importance:
Type 2 diabetes mellitus and associated chronic kidney disease (CKD) have become major public health problems. Little is known about the influence of diet on the incidence or progression of CKD among individuals with type 2 diabetes.
Objective:
To examine the association between (healthy) diet, alcohol, protein, and sodium intake, an...
INTRODUÇÃO: Novas abordagens terapêuticas que objetivam melhorar a sensação de dispneia e fadiga em pacientes com insuficiência cardíaca, como a aplicação de pressão positiva expiratória nas vias aéreas (EPAP), podem ser aplicadas na tentativa de melhorar a capacidade funcional e a qualidade de vida. OBJETIVO: Avaliar os efeitos da utilização da EP...
Background:
A growing use of telemedicine has been observed, especially as regards the sending and evaluation of electrocardiograms (ECG); this is a low-cost procedure with a high potential to save lives.
Objectives:
To describe the form of systematic analysis and user profile of the Telemedicine Network of Santa Catarina during the time when th...
Objectives:
To determine the best anthropometric index in relation to cardiovascular disease risk factors among children and adolescents.
Methods:
This cross-sectional school-based study was conducted among a random sample of 3179 students, aged 6 to 18 years, in three large cities in Brazil.
Results:
The prevalence of overweight and obesity was...
HDL-cholesterol (HDL-C) and non-HDL-cholesterol (nHDL-C) are involved in atherosclerosis. The aim of this study was to determine the distribution of HDL-C and nHDL-C and its association with cardiovascular and socio-cultural variables in a pediatric Brazilian sample.
Children and adolescents from Florianopolis were randomly selected and a structure...
The aim of this study was to estimate the prevalence, awareness, treatment, and control of systemic arterial hypertension in the adult urban population of Tubarão, Santa Catarina, Brazil. The cross-sectional approach used a stratified sample, based on an initial list of electric power connections, resulting in the selection of 707 individuals over...
The aim of this study was to estimate the prevalence, awareness, treatment, and control of systemic arterial hypertension in the adult urban population of Tubarão, Santa Catarina, Brazil. The cross-sectional approach used a stratified sample, based on an initial list of electric power connections, resulting in the selection of 707 individuals over...
The observation of a close relationship of heart rate to oxygen uptake (HH-VO2) and heart rate to minute ventilation (HR-VE)has been shown to be of particular value in rate variable pacing. However, the impact of anaerobic threshold (AT)for the HH-VO2 and HH-VE slope has been studied Jess. Twenty-three male and 16 female subjects, mean age 52 ± 7 y...
Objetivo: Descrever características clínicas, medi-das terapêuticas, evolução intra-hospitalar e de um ano após a alta de pacientes internados com insuficiência cardíaca (IC). Métodos: Estudo retrospectivo-prospectivo que avaliou todas as 385 internações de 257 pacientes ad-mitidos com IC, em 2002, no Instituto de Cardiologia de Santa Catarina. Res...
To determine the distribution of serum lipids in children and adolescents of Florianopolis, Santa Catarina State, Brazil. To determine the association between undesirable levels for total cholesterol (>170 mg/dL) and others coronary heart disease risks factors.
A questionnaire, physical examination and blood analyses were collected from randomized...
Objective
To determine the distribution of serum lipids in children and
adolescents of Florianopolis, Santa Catarina State, Brazil. To determine
the association between undesirable levels for total cholesterol
(>170 mg/dL) and others coronary heart disease risks factors.
Methods
A questionnaire, physical examination and blood analyses
were collecte...
To determine incidence rate, etiology and risk factors for central venous catheter (CVC)-related infections in critically-ill patients, a prospective cohort study was conducted in the general Intensive Care Unit (ICU) of a 212 bed Hospital in Florianópolis, Brazil.
Patients admitted to ICU between May 1993 and February 1994, exposed to short-term C...
para antagonistas de receptores de interleu -Nos ultimos anos testemunhamos o acumulo de evi-dencias sobre o papel da inflamacao na fisiopatogenia daaterosclerose e ocorrencia de eventos aterotromboticos,como determinantes dos quadros de sindromes corona-rianas agudas (SCAs) e acidentes vasculares cerebraisisquemicos
Background Other than aspirin, there are few oral antithrombotic treatments with proven efficacy in patients with acute coronary syndrome. In this report, we present the rationale, design and baseline characteristics of the Clopidogrel in Unstable angina to prevent Recurrent ischaemic Events (CURE) trial, which includes a meta-analysis of the effec...
The intracellular Gram-negative bacterium Chlamydia pneumoniae has been associated with atherosclerosis. The presence of Chlamydia pneumoniae has been investigated in fragments of the arterial wall with a technique for DNA identification.
Arterial fragments obtained from vascular surgical procedures in 58 patients were analyzed. From these patients...
To determine the incidence and risk factors associated with urinary tract infection (UTI) in patients submitted to long-term urinary (bladder) catheterization. One hundred and thirty-six patients who had urinary catheterization during the period of may to december 1993 at an University Hospital in Brazil.
Observational prospective cohort non-contro...
To assess the relationship between nondiabetic glucose levels and cardio vascular risk.
Three independent searches using MEDLINE (1966-1996), followed by a manual search of the references from each retrieved article, were conducted by two physicians and one medical librarian. Data had to be reported in at least three quantiles or intervals so that...
Cognitive feedback is a technique used for qualitative learning that has proven to be useful to train medical students. In this work we report the application of genetic algorithms to simulate this technique, using a knowledge-based system as the learner, in the domain of coronary artery disease diagnosis. The prototypical description of the diseas...
This review summarizes the results of several pharmacological interventions that have been evaluated in the management of acute myocardial infarction. Of these, thrombolytic therapy, aspirin, beta-blockers and angiotensin converting enzyme inhibitors have all been proven to reduce mortality risk and the latter three classes of drugs have also been...
This study was designed to assess the effect of acute minute ventilation sensing, rate-responsive pacing on cardiopulmonary exercise capacity in 27 patients (mean age 60 years) with chronotropic incompetence. The exercise protocol consisted of bicycle exercise in semisupine position with breath-to-breath analysis of gas exchange. At the anaerobic t...
Previous experimental and clinical studies clearly demonstrated that exogenously administered CRH possesses respiratory properties. Until now, these effects were investigated using human (h) CRH in both healthy volunteers and patients under long-term respiration. We now compared the effects of hCRH with those of ovine (o) CRH in ten healthy young m...
Normal values for cardiopulmonary bicycle exercise testing in semisupine position using a ramping protocol in a middle-aged group of untrained men and women are presented. We exercised 23 men and 16 women aged from 33 to 66 years without evidence of cardiopulmonary or cardiovascular disease and normal findings during complete heart catheterization....
In most subjects maximal exercise capacity is defined by maximal oxygen uptake (
\(\dot V\)O2 max).
According to Fick’s principle maximal oxygen consumption is the product of heart rate, arteriovenous oxygen difference, and stroke volume at maximal exercise. At lower workload stroke volume increases by the Frank-Starling-mechanism. At higher worklo...
Neuroanatomical studies on the distribution of corticotropin-releasing hormone (CRH) and its receptors (7) as well as physiological data suggest a regulatory function of endogenous CRH in hypothalamic and extrahypothalamic brain areas [1, 4]. Endogenous CRH acts within the endocrine hypothalamo-pituitary-adrenal axis and affects cardiovascular regu...
The diagnostic potential of exercise testing has been considerably enhanced by the concurrent measurement of respiratory gas exchange. The availability of rapidly responding gas analyzers together with linear air flow transducers have greatly facilitated the on-line monitoring of oxygen uptake (\(\dot V\)O2), carbon dioxide production (\(\dot V\)CO...
Anthracycline antibiotics are commonly used in the treatment of leukaemias and solid tumors in children. A well known side effect of these drugs is cardiotoxicity which may result in heart failure and in dilated cardiomyopathy.
Based on the linear relationship between cardiac output and oxygen uptake direct breath-to-breath gas exchange measurements during exercise allow accurate determinations of cardiopulmonary function. We used cardiopulmonary exercise testing to assess the physiologic benefit of rate response VVIR pacing in 17 patients with chronotropic incompetence....
Based on the linear relationship between cardiac output and oxygen uptake direct breath-to-breath gas exchange measurements during exercise allow accurate determinations of cardiopulmonary function. We used cardiopulmonary exercise testing to assess the physiologic benefit of rate response VVIR pacing in 17 patients with chronotropic incompetence....
The physical activity shows an inverse correlation with Ischaemic Cardiopathy, with evidence that lipids and lipoproteins blood levels are favourably modified by exercise. In this way, this study compared the different degrees of physical activity and the levels of blood lipids/lipoproteins, as well as the anthropometric and physiological variants....
157 males, age 21 (15-31), non-smokers. 88 athletes and 69 non-athletes. Athletes ha a higher aerobic capacity and less body fat. . Cholesterol and truglycerides were lower in athletes as well as VLDL and CT/HDL and LDL/HDL. LDL-cholesterol and HDL-colesterol did not difffer between athletes and non-athletes. There was a direct and significant corr...