Marinus H. van IJzendoorn

University College London | UCL · Department of Clinical, Educational and Health Psychology

A programmatic set of meta-analyses by Groh et al. (e.g., Groh et al., 2017a) and Madigan et al. (e.g., Madigan et al., 2023) demonstrated that secure child-caregiver attachments are positively associated with children’s social and emotional development, with somewhat stronger associations identified in relation to social competence and (lower) ext...

In Wertz et al. (2019), parents' polygenic scores of educational attainment (PGS‐EA) predicted parental sensitive responses to the child's needs for support, as observed in a dyadic task (i.e., observed sensitivity). We aimed to replicate and expand these findings by combining longitudinal data, child genotype data and several polygenic scores in t...

Children with autistic symptoms experience challenges in school settings, yet little is known about their academic profiles and the mechanisms underlying the association between autistic symptoms and academic achievement. This study examined the association between autistic symptoms and academic achievement in a population-based sample of children...

Parenting is a key contributor to child development. The effects of parenting, however, also depend on child characteristics, including genetic factors. A more complete appraisal of the role of parenting thus requires a comprehensive developmental model which explores questions about parenting behavior, child susceptibility to parenting, and child...

Background Perinatal maternal depression may affect fetal neurodevelopment directly or indirectly via exposures such as smoking, alcohol, or antidepressant use. The relative contribution of these risk factors on child executive function (EF) has not been explored systematically. Methods A prospective pregnancy cohort of 197 women and their childre...

Increased father–infant physical contact may promote early paternal caregiving. This randomized controlled trial, preregistered on https://osf.io/qwe3a, tested the effects of a soft baby carrier intervention on fathers’ parenting behavior and hormonal levels. Eighty first-time fathers of 2- to 4-month-old infants were randomly assigned to a baby ca...

Background: Lateral ventricular volume (LVV) enlargement has been repeatedly linked to schizophrenia; yet, what biological factors shape LVV during early development remain unclear. DNA methylation (DNAm), an essential process for neurodevelopment that is altered in schizophrenia, is a key molecular system of interest. Methods: In this study, we...

Background Social exclusion is often measured with the Cyberball paradigm, a computerized ball-tossing game. Most Cyberball studies, however, used self-report questionnaires, leaving the data vulnerable to reporter bias, and associations with individual characteristics have been inconsistent. Methods In this large-scale observational study, we vid...

Learning to control behavior when receiving feedback underlies social adaptation in childhood and adolescence, and is potentially strengthened by environmental support factors, such as parents. This study examined the neural development of responding to social feedback from childhood to adolescence, and effects of parental sensitivity on this devel...

The present study investigated associations between parents' secure base script knowledge and parental sensitivity and sensitive discipline in 461 families with 922 same-sex twin children (Mage = 7.00, SD = 2.18). In addition, we explored whether the strength of the associations between parents' secure base script knowledge and parental sensitivity...

During the COVID-19 pandemic lockdowns made it impossible for parenting coaches to reach the families without digital means of communication. Several studies were initiated to transform existing parenting interventions into hybrid or fully online versions and to examine their feasibility, acceptability and efficacy. We present one such transformati...

Objectives: Maternal attachment state of mind is an important potential predictor of risk and resilience to perinatal emotional wellbeing and early parenting. To explore maternal attachment in relation to perinatal depression and emotional wellbeing. Methods: This study drew on data collected within an ongoing cohort from 170 women recruited in...

Fathers have an increasingly important role in the family and contribute through their sensitive responsiveness to positive child development. Research on parenting more often included fathers as caregivers in the past two decades. We present a neurobiological model of sensitive responsive parenting with a role for fathers' hormonal levels and neur...

Support from grandparents plays a role in mothers' perinatal mental health. However, previous research on maternal mental health has mainly focused on influences of partner support or general social support and neglected the roles of grandparents. In this narrative review and meta-analysis, the scientific evidence on the association between grandpa...

To investigate the effectiveness of interventions aiming to improve hot and cold executive functions (EFs) in children and adolescents with acquired brain injury (ABI) and to examine whether characteristics of the intervention, participants, etiology of ABI (Traumatic-brain-injury [TBI] or non-TBI), time of assessment, or study quality moderate int...

Numerous meta-analyses have established associations between child maltreatment and mental health. However, variation exists between reviews regarding the magnitude of these predictions. A systematic, quantitative umbrella synthesis (i.e. meta-analysis of meta-analyses) was undertaken to describe the associations between various types of maltreatme...

Maternal sensitivity has been implicated in various aspects of child health and development, including overweight. However, long-term effects, the role of paternal sensitivity and the explanatory pathways are unclear. This study examined whether maternal sensitivity in early childhood is prospectively associated with adolescent body mass index and...

Therapists are increasingly interested in attachment theory as a potential tool to strengthen the treatment of children, youth, and families. However, attachment theory’s metaphorical language used to describe its core constructs and theoretical premises interferes with a clear translation to clinical practice. Therefore, we formulated a more concr...

Clinical practitioners are frequently encouraged, through literature, training, and policy, to learn, understand, refer to and use their knowledge of attachment theory and research when working to meet the needs of children and families. However, there has been very little empirical study of how practitioners understand and perceive the releva...

The Video-feedback Intervention to promote Positive Parenting and Sensitive Discipline (VIPP-SD) is effective in increasing parental sensitivity and sensitive discipline, and aims to decrease child behavior problems. Changes in quality of parenting may be accompanied by effects on child stress levels. However, studies of VIPP-SD effects on child be...

Childhood adversity is associated with brain morphology and poor psychological outcomes, and evidence of protective factors counteracting childhood adversity effects on neurobiology is scarce. We examined the interplay of childhood adversity with protective factors in relation to brain morphology in two independent longitudinal cohorts, the Generat...

Introduction Childhood adversities have been associated with long-lasting brain morphological differences and poor psychological outcomes over the lifespan. Evidence with regard to protective factors counteracting the detrimental effect of childhood adversity on neurobiology is scarce. Objectives Therefore, we examined the interplay of childhood a...

Substantial genetic correlations have been reported across psychiatric disorders and numerous cross-disorder genetic variants have been detected. To identify the genetic variants underlying general psychopathology in childhood, we performed a genome-wide association study using a total psychiatric problem score. We analyzed 6,844,199 common SNPs in...

Aim: This paper aims to examine the maternal and child mental health and parenting outcomes in the context of COVID-19 pandemic conditions using a sample from Melbourne, Australia - a city exposed to one of the longest lockdowns world-wide in response to the pandemic. Methods: This study utilises observational data from a prospective, pregnancy...

A potential pathway underlying the association between prenatal exposure to maternal psychological problems and childhood externalizing problems is child self-regulation. This prospective study ( N = 687) examined whether self-regulated compliance mediates the relation between maternal affective problems and hostility during pregnancy and childhood...

In molti contesti professionali, compreso quello del Tribunale per i minorenni, si fa riferimento alla teoria dell'attaccamento e alla relativa ricerca, con fraintendimenti ampiamente diffusi che spesso si traducono in applicazioni scorrette. La finalità di questa dichiarazione di consenso è, pertanto, quella di migliorarne la comprensione, contras...

Background Maternal substance use disorder (SUD) represents a risk condition for quality of parenting and child development. The current literature highlights the need to identify interventions that effectively enhance the quality of parenting and to better understand which mechanisms are involved in the process of change. The present study protoco...

How do hormonal levels in men change from pregnancy to after the birth of their firstborn child, and what is the role of oxytocin, alone or in interplay with other hormones, in explaining variance in their parenting quality? We explored in 73 first-time fathers the development of five hormones that have been suggested to play a role in parenting: o...

Maternal sensitivity and supportive discipline are important determinants of child self-regulation. Some evidence suggests that specific genetic or temperamental markers determine children’s susceptibility to the impact of maternal parenting on child self-regulation. Cortisol reactivity as a susceptibility marker moderating the relation between mat...

Background Many empirical studies suggest that higher maternal age increases the likelihood of having an autistic child. However, little is known about factors that may explain this relationship or if higher maternal age is related to the number of autistic-like traits in offspring. One possibility is that mothers who have a higher number of autist...

This study investigated behavioral and neural correlates underlying social feedback processing and subsequent aggressive behaviors in childhood in two age cohorts (test sample: n=509/n=385 and replication sample: n=354/n=195, 7-9 years old). Using a previously validated Social Network Aggression Task (Achterberg et al., 2020), we showed that negati...

This randomized, double-blind, placebo-controlled within-subject study examined the effects of intranasal administration of oxytocin and vasopressin on fathers' sensitive and challenging parenting behaviors. Furthermore, we examined the moderating role of fathers' early childhood experiences. The sample consisted of 70 fathers with their 2- to 12-m...

Temperament involves stable behavioral and emotional tendencies that differ between individuals, which can be first observed in infancy or early childhood and relate to behavior in many contexts and over many years.1 One of the most rigorously characterized temperament classifications relates to the tendency of individuals to avoid the unfamiliar a...

In their article on ‘Investigating historical abuses’ Yannick Balk, Georg Frerks and Beatrice de Graaf (2022) present an applied history of intercountry adoption to the Netherlands over the past 70 years and conclude that a moratorium on intercountry adoption is necessary because of the many adoption abuses. In this paper we comment on their aims,...

Recent studies showed that attachment security can change within persons, suggesting that there might be an interplay between a rather stable (trait) and rather variable (state) part of attachment. The study’s first aim was to investigate whether attachment priming could influence the level of state attachment. The second aim was to explore possibl...

Infant crying is a strong emotional stimulus that elicits caregiving responses in adults. Here we examine the role of empathy (measured with the Polish version of Interpersonal Reactivity Index) and salivary oxytocin in modulating sensitive responsiveness to a crying infant simulator in two groups of heterosexual couples: 111 expecting or 110 not e...

Unresolved states of mind regarding experiences of loss/abuse (U/d) are identified through lapses in the monitoring of reasoning, discourse, and behavior surrounding loss/abuse in response to the Adult Attachment Interview. Although the coding system for U/d has been widely used for decades, the individual indicators of unresolved loss/abuse have n...

Prenatal and childhood adverse events have been shown to be related to children’s cognitive and psychological development. However, the influence of early-life adversities on child brain morphology is not well understood, and most studies are based on small samples and often examine only one adversity. Thus, the goal of our study is to examine the...

Event-related potentials (ERPs) are an excellent tool for investigating parental neural responses to child stimuli. Using meta-analysis, we quantified the results of available studies reporting N170 or LPP/P3 ERP responses to children’s faces, targeting three questions: 1) Do parents and non-parents differ in ERP responses to child faces? 2) Are pa...

In a randomized double-blind within-subject control study we investigated the effects of oxytocin and vasopressin administration on neural reactivity to infant cry sounds in 70 first-time fathers in the first year of fatherhood. Additionally, we examined whether effects of oxytocin and vasopressin administration on neural reactivity were moderated...

La théorie et les recherches sur l’attachement sont utilisées dans de nombreux cadres d’application, y compris dans les tribunaux compétents en matière familiale [1], mais les incompréhensions sont fréquentes et sources d’erreurs lorsqu’il s’agit de les mettre en pratique. L’objectif de cet article de consensus est donc d’accroître la compréhension...

Objectives “Attachment difficulties” is an umbrella term often used to describe various forms of non-secure attachment. Differentiating “attachment difficulties” from autism spectrum disorder (hereafter autism) and attention deficit hyperactivity disorder (ADHD) has been characterized as challenging. Few studies have explored how this happens in pr...

The present study examined bidirectional effects between sleep problems (nocturnal awakenings and insufficient nocturnal sleep) and infant development (gross motor, fine motor, and cognition) in a sample of 182 infants (89 girls) and their parents living in Beijing (China). Using 3 waves of longitudinal data (at 6 months, 1 year, and 2 years of age...

Although clinicians typically acknowledge the importance of insecure attachment as one factor that can contribute to children’s psychopathology, translating attachment theory into clinical practice has proved a challenge. By specifying some of the mechanisms through which the child’s attachment develops and changes, learning theory can enhance atta...

In this randomized controlled trial, we investigated the effectiveness of the brief, home-based Video-feedback Intervention to promote Positive Parenting and Sensitive Discipline (VIPP-SD) in parents of 257 school-aged twin pairs (N = 514 children, Mage = 7.92, SD = 0.66), replicating a previous study testing the effectiveness of the intervention i...

The current study explored dynamics of secure state attachment expectations in everyday life in middle childhood, specifically state attachment carry-over and reactivity to experiences of caregiver support in the context of stress. In two independent samples (one community sample, N = 123; one adoption sample, N = 69), children (8–12 years) daily r...

Improving parenting, child attachment, and externalizing behaviors: Meta-analysis of the first 25 randomized controlled trials on the effects of Video-feedback Intervention to promote Positive Parenting and Sensitive Discipline (VIPP-SD). VIPP-SD combines support of parental sensitive responsiveness with coaching parents in sensitive limit setting....

In molti contesti professionali, compreso quello del Tribunale per i minorenni, si fa rife-rimento alla teoria dell'attaccamento e alla relativa ricerca, con fraintendimenti ampiamente diffusi che spesso si traducono in applicazioni scorrette. La finalità di questa dichiarazione di consenso è, pertanto, quella di migliorarne la comprensione, contra...

An unsettled question in attachment theory and research is the extent to which children's attachment patterns with mothers and fathers jointly predict developmental outcomes. In this study, we used individual participant data (IPD) meta-analysis to assess whether early attachment networks with mothers and fathers are associated with children's inte...

Typical large-group institutions for abandoned children or orphans are known to be bad for the development of children, but what about small-group care? Rygaard (2020) presents SOS Children's Villages (SOSCV) as a natural and nondetrimental setting for abandoned children. In a random effects meta-analysis, we combined the scientific evidence on the...

The quality of young children's peer relationships is important for their development, and it is assumed that parenting and self-regulation skills shape children's behavior when interacting with peers. In this multi-informant-multi-method study, we examined the direct and mediated associations between preschool parenting, children's behavioral self...

La teoría y la investigación sobre el apego se utilizan en muchos contextos aplicados, incluidos los juzgados de familia, pero hay malentendidos muy extendidos y que a veces dan lugar a aplicaciones erróneas. El objetivo de este documento de consenso es, por lo tanto, mejorar la comprensión, contrarrestar la desinformación y dirigir el uso de la te...

Background Although there is a large body of literature highlighting the behavioral effects of parenting interventions, studies on the neurocognitive mechanisms involved in such intervention effects remain scarce. Purpose The aim of the current study was to test whether changes in neural face processing (as reflected in N170 amplitudes) would act...

Background Children with autism have difficulties in understanding relationships, yet little is known about the levels of autistic traits with regard to peer relationships. This study examined the association between autistic traits and peer relationships. Additionally, we examined whether the expected negative association is more pronounced in chi...

Purpose. Support from grandparents plays a role in mothers’ perinatal mental health. However, previous research on maternal mental health mainly focused on influences of partner support or general social support and neglected the roles of grandparents. In this narrative review and meta-analysis, the scientific evidence on the association between gr...

Children with autism spectrum disorders (ASDs), attention deficit hyperactivity disorder (ADHD) and disinhibited and reactive attachment disorders (RAD/DAD) often experience socioemotional problems. Elucidating a clear picture of these profiles is essential. Strengths and Difficulties Questionnaires (SDQs) were analysed from cohort of children with...

Understanding if maternal depression is a predictor of infant-parent attachment classification is important to furthering knowledge about the early pathways and predictors of socio-emotional development. Yet few studies that have utilised the Strange Situation Procedure, the gold standard for measurement of infant-parent attachment, have examined a...

This longitudinal study examined developmental trajectories of infant sleep problems from 3 to 24 months old and investigated associations with infant-parent attachment security and dependency. In a sample of 107 Israeli families, number and duration of infant nighttime awakenings were measured at 3, 6, 9, and 24 months old, using mothers’ and fath...

The quality of parenting greatly impacts child development, highlighting the importance of support programs that effectively improve parenting. Studies on successful intervention programs define their efficacy by gains in parenting and/or child development. However, much remains unknown about the internal processes that explain how parenting interv...

Grandmothers are important in Chinese families. This study explored the early emerging mother‐grandmother‐infant network and its association with child's socioemotional development in multigenerational families in a non‐WEIRD country. The analytic sample included 60 children (T1: Mage = 6.5 months) and their caregivers residing in Beijing. Measures...

Early temperamental reactivity and attachment security are key predictors of children's social competence with peers. Leveraging meta-analytic evaluation of the significance of early attachment for social competence already available (Groh et al., 2014), this quantitative review examined the significance of early temperamental reactivity for social...