Marij Roebroeck

Erasmus MC | Erasmus MC · Department of Rehabilitation Medicine

Background For patients with post-stroke upper limb impairments, the currently available clinical measurement instruments are inadequate for reliable quantification of multiple impairments, such as muscle weakness, abnormal synergy, changes in elastic joint properties and spasticity. Robotic devices to date have successfully achieved precise and ac...

Objective: To assess test-retest reliability and validity of a new diagnostic device, the Shoulder Elbow Perturbator, to quantify muscle weakness, abnormal synergy, (muscle activity-related) spasticity, and changes in viscoelastic joint properties of the elbow. Subjects: Stroke patients, adults with cerebral palsy and healthy controls. Methods:...

Background This international, multi-center cross-sectional study is one of the preparatory studies in the development of the International Classification of Functioning, Disability and Health (ICF) Core Sets for adults with cerebral palsy (CP) to describe their functioning and health. Objective To identify the most common problems in functioning...

Aim: To: (1) investigate the importance of outcome measurement instruments (OMIs) within a core outcome set (COS) for multimorbidity (at least two chronic health conditions) risk in individuals with cerebral palsy (CP); (2) investigate the feasibility of OMIs within the COS in international clinical research settings in adolescents and adults with...

Aim To report on the results of the online international consensus process to develop the comprehensive and brief International Classification of Functioning, Disability and Health (ICF) Core Sets for adults with cerebral palsy (CP). Method An online iterative decision-making and consensus process involved 25 experts, including clinicians and rese...

Aim To examine the most relevant aspects of functioning of adults with cerebral palsy (CP) from their perspective, in order to develop an International Classification of Functioning, Disability and Health (ICF) Core Set for adults with CP. Method We conducted six focus group discussions with adults with CP without intellectual disability and seven...

Circa 30% van de mensen met een chronische aandoening ervaart problemen met arbeidsparticipatie. Aandacht voor werk is niet altijd een vanzelfsprekend onderdeel van revalidatie, en het is niet altijd bekend welke interventies gebruikt kunnen worden om de arbeidsparticipatie te verbeteren. Dit artikel beschrijft de belangrijkste bevindingen van een...

Although youth with chronic conditions have the same developmental challenges as their typical developing peers, they encounter additional bumps in the road towards adulthood because of their chronic condition. Therefore, it is important to support them in acquiring life skills (e.g. related to autonomy and participation) to be better equipped to f...

Purpose Chronic physical conditions often negatively affect work participation. The objective of this systematic review is to investigate the effectiveness and characteristics of vocational rehabilitation interventions for people with a chronic physical condition. Methods Searches in five databases up to April 2020 identified 30 studies meeting ou...

Purpose: Youth with disabilities face challenges regarding achieving autonomy. The 'Skills for Growing Up' tool was adapted for use in Dutch pediatric rehabilitation (SGU-D) to support development of autonomy. This study presents the experiences with the SGU-D tool. Methods: The SGU-D was implemented in 18 settings, of which 4 participated in th...

Objective: To identify areas of functioning in adults with cerebral palsy that are considered relevant by experts, in order to develop an International Classification of Functioning, Disability and Health (ICF) Core Set for adults with cerebral palsy. Participants: Experts from various professional backgrounds worldwide who had experience workin...

Objective: To describe the epidemiology of health status, impairments, activities and participation in adults with cerebral palsy (CP). Data sources: Embase, Medline, Web-of-Science, PsycINFO, CINAHL, Cochrane and Google Scholar were searched for three themes ('cerebral palsy', 'adult', and 'outcome assessment') in literature published between J...

Background: There is little focus on adults with cerebral palsy (CP) in research and health care and insufficient knowledge on how to identify and manage pain in this population. Objectives: This systematic review and meta-analysis aimed to determine whether pain prevalence in adults with CP is high and to explore variations in pain prevalence o...

Background: Adults with cerebral palsy (CP) may experience problems with participation in domestic life and interpersonal relationships. Aims: To identify teenage predictors of adult participation in domestic life and interpersonal relationships. Methods and procedures: This 13-year follow-up of the PERRIN 16-24 cohort included 53 adults with...

Purpose: Investigate pain, fatigue, depressive symptoms and sleep disturbance in young adults with cerebral palsy compared to references. Materials and methods: Young adults with cerebral palsy (n = 97, aged 21–34 years) and age-matched references from the general population (n = 190) rated pain using a numeric rating scale and fatigue, depressive...

Purpose: Employment of young adults with chronic physical conditions entering the labor market after finishing post-secondary education remains behind compared to typically developing peers. The aim of this study is to evaluate changes in their paid employment levels after following a vocational rehabilitation intervention (‘At Work’). Materials an...

Aim: To determine the long-term development of autonomy in participation of individuals with cerebral palsy (CP) without intellectual disability. Method: Individuals with CP (n=189, 117 males, 72 females; mean age [SD] 21y 11mo [4y 11mo], range 12-34y); were assessed cross-sectionally (46%) or up to four times (54%), between the ages of 12 and 3...

Aim: To determine development curves of communication and social interaction from childhood into adulthood for individuals with cerebral palsy (CP). Method: This Pediatric Rehabilitation Research in the Netherlands (PERRIN)-DECADE study longitudinally assessed 421 individuals with CP, aged from 1 to 20 years at baseline, after 13 years (n=121 at...

Purpose: To determine childhood predictors of participation in domestic life and interpersonal relationships of young adults with cerebral palsy (CP). Materials and methods: This 13-year follow-up of an existing cohort (baseline age 9–13 years) included 67 young adults with CP (age 21–27 years). The Vineland adaptive behavior scales (VABS) and Life...

Objective: To identify existing outcome measurement instruments (OMIs) assessing risk factors for cardiometabolic disease in adolescents and adults with cerebral palsy (CP) reported on in the literature or used in the field. Data sources: The COnsensus-based Standards for the selection of health Measurement Instruments database of systematic rev...

Background Estimates of multimorbidity, defined as the presence of at least two chronic conditions, some of which attributable to modifiable behaviours, are high in adults with cerebral palsy (CP). An assessment protocol evaluating multimorbidity risk is needed in order to develop and evaluate effective interventions to optimize lifelong health in...

Video abstract: http://pediatrics.aappublications.org/content/early/2018/10/02/peds.2017-3723 OBJECTIVES: Describe development curves of motor and daily activity performance in individuals with cerebral palsy (CP). METHODS: Participants with CP aged 1 to 20 years at baseline (n = 421) and Gross Motor Functioning Classification System (GMFCS) leve...

Aim To determine the long‐term course of difficulty in participation of individuals with cerebral palsy (CP) without intellectual disability between 16 years and 34 years of age. Method One hundred and fifty‐one individuals with CP aged 16 to 20 years were included (63% male, 37% female; Gross Motor Function Classification System [GMFCS] levels I–...

Introduction/Background Adults with cerebral palsy (CP) experience difficulties in their participation. Knowledge on the course of difficulties in participation of individuals with CP emerging into adulthood could provide insight in this stage of participation development. We aim to describe the course of difficulty and independence in participatio...

Introduction/Background Adults with cerebral palsy (CP) experience difficulties in their participation. Knowledge on the course of difficulties in participation of individuals with CP emerging into adulthood could provide insight in this stage of participation development. We aim to describe the course of difficulty and independence in participatio...

Introduction/Background Nowadays the majority of persons with cerebral palsy (CP) is of adult age. During the lifespan, adults with CP may face deterioration of health and functioning, which sets a new research area in Physical and Rehabilitation Medicine. Material and method A representative Dutch cohort of adults with CP formerly known in pediat...

Introduction/Background Knowledge on long-term development can guide expectations of young individuals with cerebral palsy (CP) and their parents and inform treatment decisions. In children with CP, development of motor capacity has been described using development curves. The present study adds to this knowledge by describing development curves of...

Objective: To determine neurological outcome in children and youth with acquired brain injury (ABI) and explore associated factors. Design: Cross-sectional study, two-years post-injury. Patients: Hospital-based sample (n=112) aged 6-22 years. Methods: Neurological outcome and participation were assessed with a multidimensional neurological examinat...

Objective: To describe longitudinal change in perceived health, presence of health issues and functional level in adults with cerebral palsy (CP). Design: Prospective cohort study. Setting: Participants who completed baseline assessments in 1996 or 2000 were invited for a long-term follow-up in 2010. Participants: Forty-nine Dutch adults wit...

Background: Finding and maintaining employment is a major challenge for young adults with physical disabilities and their work participation rate is lower than that of healthy peers. This paper is about a program that supports work participation amongst young adults with chronic physical disabilities. The study aims to explore their experienced ba...

Aims: We aimed to determine factors associated with the longitudinal development of social participation in a Dutch population of individuals with Cerebral Palsy (CP) aged 1-24 years. Methods and procedures: For this multicentre prospective longitudinal study, 424 individuals with CP aged 1-24 years were recruited from various rehabilitation cen...

Doel: Door middel van een pilotstudie evalueren van de haalbaarheid en toepasbaarheid van een nieuwe interventie, waarin revalidatie en re-integratie gecombineerd worden, om de arbeidsparticipatie te verbeteren van jongvolwassenen met lichamelijke beperkingen. Methode: twaalf jongvolwassenen (19-28 jaar) met een lichamelijke beperking hebben deelge...

Objective: To determine health-related quality of life (HRQoL) in children and youth with acquired brain injury (ABI) two years post-injury and explore associated factors. Design: Cross-sectional. Subjects: Children and youth (n = 72; aged 6-22 years) with mild to severe ABI (87% mild). Methods: The primary outcome measures self-reported and...

to assess prevalence of fatigue, pain, anxiety, and depression in adults with Duchenne Muscular Dystrophy and to analyze their relationship with health-related quality of life DESIGN: cross-sectional study SETTING: Home of participants PARTICIPANTS: 80 adults with Duchenne Muscular Dystrophy INTERVENTIONS: Not applicable MAIN OUTCOME VARIABLES: Fat...

Objective: To evaluate the cost-utility of a lifestyle intervention among adolescents and young adults with cerebral palsy. Design: Single-blind, randomized controlled trial. Setting: Six university hospital/clinics in the Netherlands. Participants: Fifty-seven adolescents and young adults with spastic cerebral palsy classified as Gross Moto...

OBJECTIVE: To assess quality of life of adults with Duchenne muscular dystrophy in the Netherlands and to identify domains and major problems influencing quality of life. DESIGN: Cross-sectional. SUBJECTS: Seventy-nine men aged ≥ 20 years with Duchenne muscular dystrophy. METHODS: The Medical Outcome Study Short Form-36 (SF-36), World Health Organi...

Transition to adulthood and adult rehabilitation care

This study aimed to assess fatigue amongst young adults with spastic cerebral palsy (CP), to determine subgroups at risk for fatigue and to explore the relationship between fatigue and cardiopulmonary fitness and daily physical activity level.Participants: Young adults with spastic CP, Gross Motor Function Classification System (GMFCS) levels I to...

Objective To 1) determine the long-term trajectory of Health-Related Quality of Life (HR-QoL) for the dimensions of physical complaints, motor-, psychological- and social functioning for groups of individuals with CP aged 1-24 years, 2) assess the variability in HR-QoL within individuals with CP over time, 3) assess the variability in HR-QoL betwee...

Objective: To evaluate the effect of a lifestyle intervention on fatigue, participation, quality of life, gross motor functioning, motivation, self-efficacy and social support, and to explore mediating effects of physical behavior and physical fitness. Design: A randomized controlled trial with intention to treat analysis. Setting: Rehabilitat...

AimOptimal physical behaviour is important, as physical inactivity contributes to functional deterioration and reduced social participation. Nevertheless, research showed that persons with cerebral palsy (CP) have low physical activity levels. The objective of this study is to evaluate the effectiveness of a lifestyle intervention programme on phys...

Introduction: Cerebral palsy (CP) is the leading cause of physical disability in childhood, causing activity limitations and participation restrictions. For young adults, achieving employment is important for independence and social participation. However, knowledge of the transition to work of young adults with CP is limited. Objective: (1) to...

Objective: To document the development of work participation in young adults with cerebral palsy who are transitioning into adulthood, examine associated characteristics, and investigate work limitations and barriers among employed persons. Design: Observational longitudinal cohort study. Subjects: Seventy-four young adults with cerebral palsy...

Objective: To describe in detail the health-related physical fitness of adolescents and young adults with cerebral palsy, compared with able-bodied references, and to assess differences related to Gross Motor Functioning Classification System (GMFCS) level and distribution of cerebral palsy. Design: Cross-sectional. Subjects: Fifty ambulatory...

To assess physical behaviour, including physical activity and sedentary behaviour, of ambulatory adolescents and young adults with cerebral palsy (CP). We compared participant physical behaviour to that of able-bodied persons and assessed differences related to Gross Motor Functioning Classification System (GMFCS) level and CP distribution (unilate...

AimThe aim of this study was to determine the developmental trajectories of expressive (speech) and receptive (spoken and written language) communication by type of motor disorder and intellectual disability in individuals with cerebral palsy (CP).Method The development of 418 participants (261 males, 157 females; mean age 9y 6mo [SD 6y 2mo], range...

Objectives To assess aspects of hand function and manual capacity that influence bimanual performance in children with congenital hand differences (CHD), ranging from surgically corrected polydactyly or syndactyly to radial dysplasia. Secondly, to assess whether in this population the number of items on the Prosthetic Upper Extremity Functional Ind...

The purpose of this study was to describe the interventions implemented in a quality improvement programme to improve transitional care and evaluate its effectiveness in reducing bottlenecks as perceived by professionals and improving chronically ill adolescents' experiences with care delivery. This longitudinal study was undertaken with adolescent...

This study aimed to determine the developmental trajectories of social participation, by level of gross motor function and intellectual disability, in a Dutch population of individuals with cerebral palsy (CP) aged 1 to 24 years. As part of the Pediatric Rehabilitation Research in the Netherlands (PERRIN+), 424 individuals with CP (261 males, 163 f...

Dit artikel is een Nederlandstalige bewerking van twee eerder gepubliceerde artikelen over deze interventie: Verhoef JAC, Miedema HS, Floothuis MSCG, Van Schaardenburgh N, Stam HJ & Roebroeck ME. A new intervention to improve work participation of young adults with physical disabilities: a feasibility study. Dev Med Child Neurol. 2013 en Verhoef J...

We investigated the influence of general self-efficacy perceived by adolescents with chronic conditions and parents on quality of life. This cross-sectional study used the general self-efficacy scale and DISABKIDS condition-generic module to survey adolescents (92/293; 31 %) with type I diabetes, juvenile rheumatoid arthritis, cystic fibrosis, kidn...

Objective: To explore: (i) cardiovascular disease risk factors and the 10-year clustered risk of a fatal cardiovascular event in adults with spastic bilateral cerebral palsy; and (ii) relationships between the 10-year risk and body fat, aerobic fitness and physical activity. Design: Cross-sectional study. Subjects: Forty-three adults with spastic b...

To determine whether the 6-minute walk test predicts peak oxygen uptake and whether the 6-minute walk test is a clinically applicable alternative to cardiopulmonary exercise testing in ambulatory adolescents and young adults with cerebral palsy DESIGN: Cross-sectional SETTING: University hospital and rehabilitation centers PARTICIPANTS: Forty-one a...

Unlabelled: Abstract Aim: To describe the occurrence and causes of acquired brain injury (ABI), including traumatic brain injury (TBI) and non-traumatic brain injury (NTBI), among Dutch youth and estimate incidence rates from the data. Patients: Aged 1 month-24 years, hospital diagnosed with ABI in 2008 or 2009. Methods: In three major hospita...

Aim: The aim of the study was to evaluate the feasibility of a new intervention to improve work participation of young adults with physical disabilities, addressing (1) implementation and costs and (2) preliminary effectiveness. Method: Twelve young adults with physical disabilities (six males, six females; age 19-28 y, median age 21 y 6 mo) par...

Purpose: The purpose of this study was to investigate into more detail how occupational performance of participants of a 1-year multidisciplinary vocational rehabilitation intervention changed over time, using a broad focus on three areas of occupational performance, addressing work, as well as self-care and leisure. In addition, we explored diffe...

Aim: The aim of this study was to describe patterns for gross motor development by level of severity in a Dutch population of individuals with cerebral palsy (CP). Method: This longitudinal study included 423 individuals (260 males, 163 females) with CP. The mean age at baseline was 9 years 6 months (SD 6y 2mo, range 1-22y). The level of severit...

Objectives To evaluate manual activity capacity (i.e. activity capacity to perform hand activities) and its relation with body functions of the hand and forearm in children with congenital hand differences (CHD) Methods We assessed 10-14 year-old children with CHD (N= 106) using a functional handgrips test. Measurements of body functions included...

Objective: To gain insight into underlying mechanisms of inactive lifestyles among adults with spastic bilateral cerebral palsy (CP) with a focus on aerobic capacity, oxygen consumption, and physical strain during walking at preferred walking speed, as well as fatigue. Design: Cross-sectional. Setting: University hospital. Participants: Adul...

: To examine the intelligibility and psychometric properties of the modified Dutch language version of the Work Limitations Questionnaire (WLQ) (WLQ-mdlv). : Employed patients with a physical chronic condition completed the WLQ-mdlv, the Work Ability Index, and the 36-item short form health survey. Intelligibility, internal consistency, test-retest...

To investigate the prevalence and co-occurrence of chronic pain, fatigue, and depressive symptoms in adults with spastic bilateral cerebral palsy (SBCP) and explore associations of chronic pain and fatigue with depressive symptoms and daily functioning. Fifty-six adults with SBCP without severe cognitive impairment participated (35 males, 21 female...

Background Teenagers with physical disabilities are challenged in achieving autonomy. In Canada, an instrument has been developed for young persons aged 7-21 years to support autonomy development and participation. Aim To test the feasibility and efficacy of the Dutch version of Skills for Growing Up (dSGU). Methods An expert panel drafted a pilo...

To determine agreement between children with congenital hand differences (CHDs) and their parents on health-related quality of life (HRQOL) and to explore whether characteristic variables were associated with this agreement on different domains of HRQOL. Survey. University hospital, outpatient clinic. Children with CHD (age range, 10-14 y; N=106)....

To study determinants of romantic relationships and sexual activity of young adults with cerebral palsy (CP), focusing on personal and environmental factors. A cohort study was performed with 74 young adults (46 men; 28 women) aged 20-25 years (SD 1.4) with CP (49% unilateral CP, 76% GMFCS level I, 85% MACS level I). All participants were of normal...

To describe subjective caregiver burden of parents of adults with Duchenne muscular dystrophy (DMD) and to identify factors associated with the level of subjective burden. In a cross-sectional study in 80 parents of 57 adult, severely disabled DMD patients' level of subjective caregiver burden was measured with the Caregiver Strain Index (CSI) and...

Traumatic brain injury (TBI) is in the developed countries the most common cause of death and disability in childhood. The purpose of this study is to estimate the incidence of TBI for children and young people in an urbanised region of the Netherlands and to describe relevant characteristics of this group. Patients, aged 1 month - 24 years who pre...

To determine upper limb function and associated factors in adults with Duchenne muscular dystrophy. Cross-sectional study. A sample of 70 men with Duchenne muscular dystrophy (age range 20-43 years). General motor function and, in particular, upper limb distal motor function, were assessed with the Motor Function Measure. Muscle strength and range...

Objective of this study is to describe the problems young adults with Cerebral Palsy (CP) experience in the various stages of the sexual response cycle, and the physical and emotional obstacles they experience with sexuality. In this prospective cohort study 74 young adults (46 men; 28 women) with CP and average intelligence participated, aged 20-2...

Persons with cerebral palsy (CP) are at risk for developing an inactive lifestyle and often have poor fitness levels, which may lead to secondary health complications and diminished participation and quality of life. However, persons with CP also tend not to receive structural treatment to improve physical activity and fitness in adolescence, which...

. To describe the development of romantic relationships and sexual activity of young adults with cerebral palsy (CP), to investigate whether this development is associated with demographic and physical characteristics, and to compare the sexual activity of this group with an age-appropriate Dutch reference population. Prospective longitudinal study...

To assess participation and health-related quality of life in adults with bilateral spastic cerebral palsy, and explore associations with self-efficacy. Cross-sectional study. A sample of 56 adults with bilateral spastic cerebral palsy (mean age 36.4 (standard deviation 5.8) years; 62% male). Daily activities and social participation (Life Habits 3...