Mariia Shanaida

Mariia Shanaida
I. Horbachevsky Ternopil National Medical University · Pharmacognosy and Medical Botany Department

DSc; PhD; Associate Professor

About

118
Publications
27,280
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321
Citations
Citations since 2016
101 Research Items
316 Citations
2016201720182019202020212022020406080100120140
2016201720182019202020212022020406080100120140
2016201720182019202020212022020406080100120140
2016201720182019202020212022020406080100120140
Introduction
Phytochemical analysis of plants. Biological activity of natural products. Nutritional Pharmacology

Publications

Publications (118)
Article
Full-text available
Winter Savory (Satureja montana L.) has been used in traditional medicine and as a spice or natural food preservative in the Mediterranean region for centuries. In this paper, some technological and analytical aspects of the S. montana tinctures development and an evaluation of the essential oil composition are provided. The total phenolic and flav...
Article
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The present study was focused on the chemical composition and antimicrobial activity of the essential oils (EsO) obtained from five Lamiaceae representatives grown in the south of Ukraine. Among them are Salvia sclarea L., Monarda didyma (cultivar ‘Cambridge Scarlet’), Thymus pulegioides (cultivar ‘2/6-07’), Thymus vulgaris (cultivar ‘Jalos’), and...
Article
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Polyphenols (PPs) are a large group of phytochemicals containing phenolic rings with two or more hydroxyl groups. They possess powerful antioxidant properties, multiple therapeutic effects, and possible health benefits in vivo and in vitro, as well as reported clinical studies. Considering their free-radical scavenging and anti-inflammatory propert...
Article
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Aging is a very complex process that is accompanied by a degenerative impairment in many of the major functions of the human body over time. This inevitable process is influenced by hereditary factors, lifestyle, and environmental influences such as xenobiotic pollution, infectious agents, UV radiation, diet-borne toxins, and so on. Many external a...
Data
Dear Colleagues! Essential oils are a complex mixture of plant volatile compounds which are mainly terpenoids or phenolic compounds for their nature. These compounds are synthesized in dedicated cell types present in almost all parts of the plant, from roots and leaves to flowers and fruits. There is a huge difference between chemotypes of the same...
Article
Full-text available
ntroduction. The genus Vitex L. counts more than 200species of shrubs and trees common to subtropical areasof the Earth. Only fruits of Vitex agnus-castus L. are usedin official medicine.The aim of our study was to perform the chromatographicanalysis of carboxylic acids in the flowering shoots of threeVitex representatives under their cultivation i...
Article
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The current review provides an up-to-date analysis of scientific data on astaxanthin (ASX) sources and experimental studies on its health benefits as a potent antioxidant in the aging process. ASX is a liposoluble carotenoid nutrient and reddish-orange pigment, naturally synthesized by numerous microalgae, yeasts, and bacteria as secondary metaboli...
Article
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Aging is characterized by an imbalance between damage inflicted by reactive oxygen species (ROS) and the antioxidative defenses of the organism. As a significant nutritional factor, the trace element selenium (Se) may remodel gradual and spontaneous physiological changes caused by oxidative stress, potentially leading to disease prevention and heal...
Article
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The COVID-19 outbreak seems to be the most dangerous challenge of the third millennium due to its highly contagious nature. Amongst natural molecules for COVID-19 treatment, the flavonoid molecule quercetin (QR) is currently considered one of the most promising. QR is an active agent against SARS and MERS due to its antimicrobial, antiviral, anti-i...
Article
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Chronic exposure to arsenic (As) compounds leads to its accumulation in the body, with skin lesions and cancer being the most typical outcomes. Treating As-induced diseases continues to be challenging as there is no specific, safe, and efficacious therapeutic management. Therapeutic and preventive measures available to combat As toxicity refer to c...
Article
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The aim. Extracts of cranberry large leaves have prospects when used to correct insulin-resistant conditions. There­fore, to create new drugs based on cranberry leaves, you need to develop instructions for cultivating the plant, harvesting raw materials and methods of quality control. Therefore, the aim of the research was to determine the pa­ramet...
Article
Full-text available
Introduction. The genus Vitex L. counts more than 200 species of shrubs and trees common to subtropical areas of the Earth. Only fruits of Vitex agnus-castus L. are used in official medicine. The aim of our study was to perform the chromatographic analysis of carboxylic acids in the flowering shoots of three Vitex representatives under their culti...
Article
Full-text available
Мета роботи. Провести ідентифікацію поліфенолів та терпеноїдів у траві Thymus pulegioides (сорт «2/6-07»), Thymus richardii (сорт «Fantasy») і Thymus vulgaris (сорт «Jalos») з використанням методу тонкошарової хроматографії (ТШХ), а також здійснити газохроматографічний аналіз ефірної олії Thymus richardii. Матеріали і методи. Метод тонкошарової хро...
Preprint
Full-text available
ABSTRACT The aim of the work. To perform the identification of phenolic compounds and terpenoids in the aerial parts of Thymus pulegioides L. (cultivar '2/6-07'), Thymus richardii Pers. (cultivar 'Fantasy') and Thymus vulgaris L. (cultivar 'Jalos') using thin layer chromatography (TLC), as well as to conduct the gas-chromatographic analysis of Thym...
Article
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Silica nanoparticles were applied as the carrier of chloramphenicol (2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide), and were loaded in a 1% carbopol-based gel (poly(acrylic acid)), which allowed obtainment of an upgraded drug form. The samples of silica materials were obtained by means of modified Stöber synthesis, a...
Article
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Abstract: This review aims to analyze propolis as a potential raw material for the development and manufacture of new health-promoting products. Many scientific publications were retrieved from the Scopus, PubMed, and Google Scholar databases via searching the word “propolis”. The different extraction procedures, key biologically active compounds,...
Article
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The increased emotional stress and anxiety in the modern human life are common causes of mental health problems which substantially grown during the COVID-19 pandemic. Timely intake of phytosedatives could mitigate the impact of stressful situations and reduce the risk of psychosomatic diseases. Essential oil-bearing plants belonging to the Lamiace...
Article
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Essential oils isolated from medicinal plants are the rich source for developing new herbal medicinal products. The genus Vitex L. (Lamiaceae Martinov family) contains more than 200 species of essential-oil bearing plants. The gas-chromatographic determination of volatiles from the flowering shoots of three Vitex representatives (V. agnus-castus, V...
Article
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The Nigella (Nigella L.) genus includes 18 species of annual herbaceous plants which seeds are used in folk medicine and cooking around the world. Only Nigella sativa L. has been characterized sufficiently in terms of chemical constituents or pharmacological properties. The aim of the study was to conduct the gas chromatography mass spectrometric (...
Article
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The Mentheae Dumort. is the largest tribe in the Nepetoideae Burnett subfamily of the Lamiaceae Marinov family. The unofficial medicinal plants of the Mentheae tribe are of great interest for pharmacy and food industry. The representatives of the Hyssopus L., Agastache Gronov, Monarda L., and Satureja L. genera are gradually spreading in Ukraine as...
Article
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Analysis of scienti c and educational publications of the Ukrainian and foreign authors, as well as author's own expe rience in managing of the student scienti c activities in the pharmaceutical eld, proves the importance of involving applicants in higher education in 226 «Pharmacy, Industrial Pharmacy» scecialty to acquire additional skills of stu...
Article
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The genus Dracocephalum L. (Lamiaceae Martinov family) includes 72 species of essential oil bearing plants with promising biological activities. They belong to the category of unofficial medicinal plants. The most studied group of the bioactive compounds of Dracocephalum species are essential oils and polyphenols, while the other components have be...
Article
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The yield of essential oils in plants is not high and postdistillation wastes rich in phenolic compounds could be used to enhance the profitability of essential oil-bearing plants. The aim of the study was to evaluate polyphenols in a dry extract obtained from the postdistillation waste of the American basil (Ocimum americanum L.) herb, and to cond...
Article
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Background: Discoloration of teeth occurs for various reasons. Common ingredients like substances from tea and coffee, as well as antibiotics like tetracycline, or food dyes, can percolate into the teeth, and, as such, these stains may persist in the porous structure of the enamel. Smoking is also contributory to dental discoloration, with toxins o...
Article
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The aim of the work. Phytochemical analysis of terpene compounds in the herbs of three representatives of the tribe Mentheae belonging to the Lamiaceae family (Dracocephalum moldavica L., Lophanthus anisatus (Nutt.) Benth and Satureja hortensis L.) by chromatographic and spectrophotometric methods. Materials and Methods. The herbs of plants were ha...
Article
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The genus Dragonhead (Dracocephalum L.) includes 72 species of essential oil-bearing plants belonging o the Lamiaceae family. Many of them have long been used in a folk medicine of different countries. Moldavian dragonhead (D. moldavica L.) has been identified as the most promising species for the complex phytochemical research since it was success...
Conference Paper
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Gas chromatography mass spectrometry (GC-MS) method has been used in this study for the evaluation of compositions of essential oils and carboxylic acids in the flowering shoots of the Vitex species.
Article
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Purpose. To determine mineral composition of plants of species of the genus Artemisia (A. dracunculus L., A. abrotanum L. and A. argyi H.Lév. & Vaniot) to determine the possibility of their safe use in the food and pharmaceutical industries of Ukraine. Methods. X‑ray fluorescence method for determining the elemental composition of plant raw materia...
Article
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Background and objectives: The health promoting properties of aromatic medicinal plants are of great importance for the pharmaceutical and food industries. Methods: the chromatographic analysis of phenolic compounds in the summer savory (Satureja hortensis L.) herb cultivated in western Ukraine was carried out using high-performance thin layer chro...
Article
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Due to its vast therapeutic potential, the plant-derived polyphenol curcumin is utilized in an ever-growing number of health-related applications. Here, we report the extraction methodologies, therapeutic properties, advantages and disadvantages linked to curcumin employment, and the new strategies addressed to improve its effectiveness by employin...
Article
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The aim of this study was the comparative analysis of phenolic compounds in the Ocimum americanum and Monarda fistulosa herbs using high-performance liquid chromatography (HPLC) method and the spectrophotometric evaluation of the total hydroxycinnamic derivatives (THD) contents. Rosmarinic acid (RAc) was the predominant phenolic compound of both in...
Article
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Phytochemical and pharmacological studies of non-officinal species among essential oil-bearing plants are promising areas of modern Pharmacognosy. The aim of the research was the experimental study the pharmacological activities and safety of a dry extract obtained from the Lophanthus anisatus herb (LAE) and evaluation its polyphenols using high pe...
Article
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Use of the natural sedatives is very promising for the elimination of anxiety and emotional stress. The aim of the study was to evaluate the chemical compositions and sedative effects of the Dracocephalum moldavica L. and Ocimum americanum L. (Lamiaceae Martinov) essential oils. The chromatographic analyses of essential oils revealed the high amoun...
Conference Paper
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The genus Monarda L. (Lamiaceae Martinov family) includes several species of essential oils-bearing herbaceous plants native to North America. Nowadays they are widely distributed. Only limited portions of information are available about 'chromatographic fingerprint' analysis of wild bergamot (Monarda fistulosa L.) aerial part and its isolates. The...
Conference Paper
Full-text available
Plants of the Lamiaceae Martinov family are very useful for people because of their medicinal properties. They are rich in essential oils and polyphenols with valuable healing effects. The development of chromatographic methods for the identification of this family representative's raw materials is a perspective trend for the pharmaceutical industr...
Article
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The aim of the research is to study the effect of L-arginine, the precursor of nitric oxide, and aminoguanidine, the inhibitor of inducible nitric oxide synthase, on morpho-functional changes in the liver of BALB/c mice with antiphospholipid syndrome. The study was carried out on 50 female BALB/c mice modelled with antiphospholipid syndrome. L-argi...
Article
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Мета роботи. Хроматографічний аналіз ефірних олій монарди лимонної (Monarda citriodora Cerv. ex Lag, родина Lamiaceae Martinov), отриманих із трави рослини в різні фази вегетації. Матеріали і методи. Матеріалом для досліджень була трава M. citriodora, яку заготовляли на дослідних ділянках у Херсонській області на початку цвітіння та у період масов...
Article
Full-text available
Two different methods of chromatographic analysis have been used in this study for the phytochemical evaluation of main secondary metabolites in the aerial part of bee balm (Monarda fistulosa L.) as the non-officinal medicinal plant of the Lamiaceae Martinov family. The high performance thin layer chromatography (HPTLC) fingerprinting method was de...
Article
Full-text available
This study aimed to determine the composition and content of polyphenols in the dry extract obtained from the hydrodistilled residue by-product of the wild bergamot (Monarda fistulosa L., Lamiaceae Martinov family) herb (MFDE) and to evaluate its safety and pharmacological properties. The total phenolic content (TPC) in the MFDE was 120.64 mg GAE/g...
Article
Full-text available
The component composition of Monarda citriodora (Lamiaceae) essential oils was studied by GC/MS. There were identified 28 components in the essential oil obtained from the herb during the beginning of flowering, and 27 compounds were found during the total flowering of plants. The predominant components of both essential oils were aromatic monoterp...
Conference Paper
Full-text available
This study was focused on the chemical composition and antimicrobial activity of the essential oils obtained from the three Thymus species: T. serpyllum L. T. pulegioides L. and T. richardii Pers. The aerial parts of plants were collected in the flowering stage in Kherson region (Ukraine). The isolation of the essential oils was performed by hydrod...
Article
Full-text available
Sedative phytomedications continue to play an important role in the management of a considerable amount of anxiety symptoms because of the various side effects of synthetic sedatives and tranquilizers. However, developing new herbal drugs needs their appropriate quality control according to the relevant requirements. The aim of the study was to det...
Conference Paper
Full-text available
The aim of the study was chromatographic analysis of essential oil and polyphenols of the hydrodistilled residue by-product developed from the O. americanum herb. Plant raw material was harvested from the experimental plots in Ternopil region (Ukraine) and shade dried. Hydrodistillation method was used to obtain the essential oil from O. americanum...
Conference Paper
Full-text available
The issues of development of effective and safe herbal medicines with antioxidant, anti-inflammatory and sedative effects for use in dentistry, dermatology, neurosis prevention, etc. are relevant. Previous research has established the prospects for the study and use in medical practice of a number of unofficial species of the Lamiaceae family (Drac...
Conference Paper
Full-text available
Involvement of students of the Faculty of Pharmacy to participate in the Olympiad in Pharmaceutical Botany contributes to the formation of highly qualified specialists who acquire in-depth knowledge, skills and abilities to identify medicinal plants by morphological and anatomical features, expand their worldview on ecological and ecological specie...
Conference Paper
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Introduction: Summer savory (Satureja hortensis L.) is an annual herbaceous plant belonging to the Lamiaceae family [1, 2]. S. hortensis volatile oils contains such main components as thymol (0.3–28.2%), γ-terpinene (15.30–39%), carvacrol (11–67%), and p-cymene (3.5–19.6%). The herb of S. hortensis is rich in polyphenols [1]. Therefore, this herb c...
Conference Paper
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Introduction: Species of the Monarda L. genus are the endemics of North America. In recent decades many of them are spread to Europe as cultivated plants with ornamental and promising healing properties [1]. Materials and methods: Compositions of the essential oils hydrodistilated from the flowering aerial parts of four Monarda species (M. citriodo...
Article
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У світовій медичній практиці спостерігається тенденція до збільшення використання питомої част-ки лікарських засобів, які виготовляються на основі лікарської рослинної сировини. У зв'язку з цим визначено необхідність з'ясувати перспективу подальшого наукового вивчення і застосування рослинної сировини й пре-паратів на основі шавлії лікарської (Salv...
Article
Full-text available
Many diseases, including caries, chronic inflammatory diseases, diabetes, and obesity, are associated with uncontrolled sugar consumption. Artificial sweeteners are commonly used in food and pharmaceutical industries as sugar substitutes for the prevention of several dental and body diseases; they also have a favorable impact on body weight as they...
Preprint
Nova.Main@novapublishers.com Species of the Basil (Ocimum L.) genus of the Mint (Lamiaceae Martinov) family have been used in traditional and complementary medicine from the ancient time. Several of them are commonly known everywhere in the world as food, spices and medicines. Traditional use of Ocimum species are treatment of common cold, rheumati...
Article
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Microscopical characteristic of plants is important for identification of medicinal plant material and establishing parameters of its quality. Determination of diagnostic anatomical features of Monarda fistulosa L. aerial part as non-officinal medicinal plant is relevant task of pharmaceutical science and practice. The purpose of this study was mic...
Article
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Aim: Representatives of Nepetoideae Burnett subfamily are promising species of the Lamiaceae Martinov family because of accumulating such valuable groups of secondary metabolites as terpenoids and polyphenols. A high-performance thin layer chromatography (HPTLC) fingerprint method for the qualitative determination of phenolic compounds and for the...
Patent
The invention relates to the developing of a herbal rmedicinal product with anti-inflammatory and analgesic activity from the Monarda fistulosa herb. It involves the step of hydrodistillation of the raw material and post-distillation extraction with 50% ethanol, followed by evaporation of the obtained extracts, combining them and drying to a powder...
Conference Paper
Full-text available
The purpose of the present study was to develop the high performance thin layer chromatography (HPTLC) and high performance liquid chromatography (HPLC) methods for evaluating the phenolic compounds in 70 % ethanol extracts from aerial parts of selected Nepetoideae species: Dracocephalum moldavica, Ocimum americanum, Lophanthus anisatus, Monarda fi...
Article
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Calanus oil (COil) is a natural product extracted from marine zooplankton Calanus finmarchicus found in the North Atlantic Ocean. This oil is rich in wax esters of polyunsaturated fatty acids (PUFAs) and has been projected as the best alternative to fish oil because its production cannot keep pace with the demands from the growing markets. The COil...
Article
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Polyphenols are valuable group of phytoconstituents due to their high antioxidant activity and healing properties. Antioxidant properties of sages are attributed mainly to a high level of phenolic compounds. The aim of the present study was to elaborate an analytical procedure for the evaluation of the content of secondary metabolites of the polyph...
Conference Paper
Full-text available
The purpose of the study was to determine the HPTLC fingerprints of plant raw materials, extracts and essential oils obtained from Lophanthus anisatus, Monarda fistulosa, Ocimum americanum, Dracocephalum moldavica and Satureja hortensis (Lamiaceae), and developing the qualitative parameters of standardization for these perspective medicinal product...
Conference Paper
Full-text available
The genus Salvia L., is one of the largest in the Lamiaceae family. Salvia verticillata L. is used for various diseases in folk medicine and as honey plants. The purpose of the work is to investigate the variability of bioecological and morphological characteristics of plants and seeds of the species S. verticillata, to select high-yield forms for...
Conference Paper
Full-text available
The purpose of this study was the chromatographic analysis of phenolic compounds and rosmarinic acid (RA) quantification in Monarda fistulosa herb by HPTLC method. The HPTLC chromatograms of ethyl acetate, butanol, and water fractions showed the intense light blue fluorescent zone at Rf=0.75±0.01 corresponding to reference of RA. Weaker light blue...
Article
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Nigella sativa та N. damascenа Актуальність. Не дивлячись на використання насіння видів роду Чорнушка (Nigella L.) у народній медицині різних країн та наявності експериментальних даних стосовно його здатності виявляти різні види біологічної активності, сировина цих рослин не входить до вітчизняної та світових фармакопей; у «Державному реєстрі лікар...
Article
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Трава чаберу гірського (Satureja montana L., Lamiaceae) як перспективна лікарська сировина для розробки антимікробних та антиоксидантних засобів Вступ. Для виявлення нових потенційних джерел антимікробних та антиоксидантних рослинних засобів важливе значення має аналіз джерел наукової літератури стосовно фітохімічних та фармакологічних досліджень н...
Article
Газохроматографічний аналіз ефірної олії насіння рослини показав домінування карвону (46,6%)
Article
Full-text available
Introduction. An analysis of sources of scientific literature concerning phytochemical and pharmacological studies of non-officina medicinal plants is important for the identification of new potential sources of antibacterial and antioxidant plant products. Significant interest in this regard is caused by the biologically active substances of the W...
Conference Paper
Full-text available
The results of the V. agnus-castus, V. negundo and V. negundo var. cannabifolia introduction in the National Botanical Garden by M. M. Hryshko of NAS of Ukraine (Kyiv). The component composition of the essential oils obtained from the flowering shoots of these plants has been established. The prospect of the use of raw material of these plants as a...