Marie Sárazová

Marie Sárazová
University of Münster | WWU · Institute for Evolution and Biodiversity

MSc./Mgr.

About

5
Publications
1,313
Reads
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235
Citations
Additional affiliations
July 2019 - present
Monasterium Laboratory Skin and Hair Research Solutions GmbH
Position
  • Research Assistant
September 2009 - June 2011
Masaryk University
Position
  • Master's Student
August 2017 - May 2019
Monasterium Laboratory Skin and Hair Research Solutions GmbH
Position
  • Technician
Education
September 2009 - June 2011
Masaryk University
Field of study
  • Biochemistry
September 2006 - June 2009
Masaryk University
Field of study
  • Biochemistry

Publications

Publications (5)
Article
Full-text available
Ribosome assembly is an essential process that is linked to human congenital diseases and tumorigenesis. While great progress has been made in deciphering mechanisms governing ribosome biogenesis in eukaryotes, an inventory of factors that support ribosome synthesis in human cells is still missing, in particular regarding the maturation of the larg...
Article
High-content, imaging-based screens now routinely generate data on a scale that precludes manual verification and interrogation. Software applying machine learning has become an essential tool to automate analysis, but these methods require annotated examples to learn from. Efficiently exploring large datasets to find relevant examples remains a ch...
Article
Full-text available
Ribosome biogenesis is a highly complex process requiring many assisting factors. Studies in yeast have yielded comprehensive knowledge of the cellular machinery involved in this process. However, many aspects of ribosome synthesis are different in higher eukaryotes, and the global set of mammalian ribosome biogenesis factors remains unexplored. We...
Article
Full-text available
Trf4/5p-Air1/2p-Mtr4p polyadenylation complex (TRAMP) is an essential component of nuclear RNA surveillance in yeast. It recognizes a variety of nuclear transcripts produced by all three RNA polymerases, adds short poly(A) tails to aberrant or unstable RNAs and activates the exosome for their degradation. Despite the advances in understanding the s...

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