Marie MorelUniversité de Bretagne Occidentale | UBO · INSERM UMR 1227 - LBAI
Marie Morel
PhD Student
About
3
Publications
167
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6
Citations
Citations since 2017
Introduction
I studied immunology at the University of Bordeaux and started my thesis at the LBAI laboratory in Brest under the supervision of Professor Anne Bordron. This project focuses on stratification and prediction of response to targeted therapies by highlighting the importance of the glycosylation. This work will provide a better understanding of glycosylation in pathologies such as chronic lymphocytic leukemia and autoimmune disorders.
Publications
Publications (3)
Systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome (pSS) are two autoimmune diseases characterised by the production of pathogenic autoreactive antibodies. Their aetiology is poorly understood. Nevertheless, they have been shown to involve several factors, such as infections and epigenetic mechanisms. They also likely involve a physi...
Autoimmune disease development depends on multiple factors, including genetic and environmental. Abnormalities such as sialylation levels and/or quality have been recently highlighted. The adjunction of sialic acid at the terminal end of glycoproteins and glycolipids is essential for distinguishing between self and non-self-antigens and the control...
