Marie-Elisabeth Faymonville

Marie-Elisabeth Faymonville
Centre Hospitalier Universitaire de Liège | CHU de Liège · Service d'algologie

MD;PhD

About

139
Publications
38,499
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7,075
Citations
Citations since 2017
36 Research Items
1937 Citations
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2017201820192020202120222023050100150200250300
2017201820192020202120222023050100150200250300

Publications

Publications (139)
Article
Background: Virtual reality hypnosis (VRH) has emerged as a new and promising option for pain management. Nonetheless, neural dynamics of pain modulation during VRH have not been investigated yet. The aim of this study was to measure the effects of VRH on pain, combining neurophysiological and self-reported measurements. Methods: Eighteen health...
Article
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Phantom limb pain occurs in more than half of the people who have undergone an amputation. Hypnosis can alleviate pain effectively in experimental, procedural, and chronic pain. Thus, in this multiple-case study, we determined whether hypnosis might be a successful complementary approach to help patients with phantom limb pain in alleviating their...
Article
Purpose of the review: Cancer-related fatigue (CRF) and sleep disturbances are common symptoms among patients with cancer. They are often conceptualized as a part of a larger symptom cluster, also comprising pain and emotional distress. Despite their prevalence and long-lasting effects, CRF and sleep disturbances are still poorly addressed in clin...
Article
Cancer can provoke fatigue, sleep disturbances, and emotional distress. Hypnosis interventions have shown positive short-term effects on these symptoms. However, less is known about their long-term effects. This study assessed the short- and long-term effects of a group intervention combining self-care and self-hypnosis on these symptoms in posttre...
Article
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Patients with locked-in syndrome (LIS) may suffer from pain, which can significantly affect their daily life and well-being. In this study, we aim to investigate the presence and the management of pain in LIS patients. Fifty-one participants completed a survey collecting socio-demographic information and detailed reports regarding pain perception a...
Article
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Introduction A symptom cluster is very common among oncological patients: cancer-related fatigue (CRF), emotional distress, sleep difficulties, pain, and cognitive difficulties. Clinical applications of interventions based on non-ordinary states of consciousness, mostly hypnosis and meditation, are starting to be investigated in oncology settings....
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Chronic pain is a complex phenomenon which includes biological, psychological, and socio-professional factors that undermine patients’ everyday life. Currently, only few patients significantly benefit from pharmacological treatments and many have to stop them because of negative side effects. Moreover, no medication or treatment addresses all aspec...
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Background: Virtual reality and hypnosis are little studied in complex contexts, such as intensive care, where patients need significant physical and psychological assistance. Objectives: To compare and combine hypnosis and virtual reality benefits on anxiety and pain on patients before and after cardiac surgery. Design: Prospective randomised...
Article
Background: In chronic pain, it seems that the effect of cognitive-behavioral therapy (CBT) is boosted when it is combined with hypnosis. The aim of this study was to assess the efficacy of self-hypnosis combined with self-care (i.e., a type of CBT) compared to music/self-care, self-care and psychoeducation/CBT and to evaluate their long-term effe...
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Objective: To identify profiles of patients who are at risk of dropping out from biopsychosocial approaches to chronic pain management. Patients: A total of 575 patients were included in the study. Of these, 203 were randomized into 4 treatment groups: self-hypnosis/self-care; music/self-care; self-care; and psychoeducation/cognitive behavioural...
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Emotional distress, communication, and dyadic coping difficulties are common among cancer patients and their partners. Hypnosis-based interventions can improve emotional distress in patients. We designed a group intervention combining self-hypnosis and self-care techniques. We hypothesized an effect of the intervention on emotional distress, conjug...
Preprint
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Background: Although non-pharmacological tools are nowadays commonly used in medical settings, virtual reality and hypnosis are little studied in complex contexts such as intensive care, where patients need significant physical and psychological assistance. The aim of the project is to evaluate the benefits of hypnosis, virtual reality (VR) and the...
Article
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Cet article vise à comprendre comment les processus impliqués en hypnose peuvent augmenter le confort des patientshospitalisés aux soins intensifs. L’hypnose est un outil de plus en plus utilisé par les équipes médicales comme techniquecomplémentaire aux approches biomédicales usuelles. De nombreuses études ont démontré ses effets dans différentsco...
Article
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Hypnosis is well documented in the literature in the management of acute and chronic pain. Virtual reality (VR) is currently gaining credibility in the same fields as hypnosis for medical applications. Lately, the combination of hypnosis and VR was considered. The aim of this scoping review is to understand the current studied contexts and effects...
Article
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Background: Different non-pharmacological techniques, including hypnosis and virtual reality (VR) are currently used as complementary tools in the treatment of anxiety, acute and chronic pain. A new technique called virtual reality hypnosis (VRH), which encompasses a combination of both tools, is regularly used although its benefits and underlying...
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The neurobiological basis of near-death experiences (NDEs) is unknown, but a few studies attempted to investigate it by reproducing in laboratory settings phenomenological experiences that seem to closely resemble NDEs. So far, no study has induced NDE-like features via hypnotic modulation while simultaneously measuring changes in brain activity us...
Article
Résumé L’hypnose est une pratique de plus en plus courante en milieu hospitalier. Ainsi, en oncologie pédiatrique cette technique est efficace pour la gestion de l’anxiété et de la douleur liée à la maladie, aux traitements ou à des procédures invasives. L’hypnose et l’autohypnose améliorent aussi le confort et de bien-être des enfants malades et d...
Chapter
Hypnosis is a technique which induces changes in perceptual experience by responding to specific suggestions. By means of functional neuroimaging, a large body of clinical and experimental studies has shown that hypnotic processes modify internal (self awareness) as well as external (environmental awareness) brain networks. Objective quantification...
Article
Many children with cancer and their parents suffer from distress, fatigue, and relational difficulties. Hypnosis is often used to decrease children’s procedure-related pain and distress in pediatric oncology and to improve the well-being of adults with cancer. This article describes a pilot study assessing the acceptability and feasibility of a gro...
Article
This study explored absorption, dissociation, and time perception on visual analogue scales (VAS) after a neutral hypnosis session to predict hypnotizability. Sixty-two subjects completed the Stanford Hypnotic Susceptibility Scale, Form C (SHSS:C) and, during a neutral hypnosis session, VAS ratings of absorption, dissociation, and time perception....
Chapter
This chapter reviews current knowledge of the effects of hypnotic anesthetic agents on brain resting-state networks (RSNs) that sustain consciousness. Although full exploration of the networks under anesthesia is not yet available, current evidence indicates that anesthetic agents with hypnotic properties dose-dependently modulate RSN functioning....
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Background Cancer has a lot of consequences on patients’ quality of life (such as cancer-related fatigue (CRF), sleep difficulties and emotional distress) and on patients’ partners and their relationship, such as distress and communication difficulties. These consequences are undertreated, and interventions based on hypnosis often focus on breast c...
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Despite recent advances in our understanding of consciousness disorders, accurate diagnosis of severely brain-damaged patients is still a major clinical challenge. We here present the case of a patient who was considered in an unresponsive wakefulness syndrome/vegetative state for 20 years. Repeated standardized behavioral examinations combined to...
Article
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Objective: The aim of the study is to explore the possibility of oral feeding in unresponsive wakefulness syndrome/vegetative state (UWS/VS) patients. Method: We reviewed the clinical information of 68 UWS/VS patients (mean age 45 ± 11; range 16-79 years) searching for mention of oral feeding. UWS/VS diagnosis was made after repeated behavioural a...
Article
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Depuis quelques années, il est de plus en plus clair que l’hypnose présente un champ de recherche fondamentale et appliquée important. L’Hôpital Universitaire (CHU) ainsi que l’Université de Liège font partie des centres pionniers s’intéressant à l’étude de l’hypnose en tant qu’objet de recherche. Ces équipes ont pour objectif de comprendre les bas...
Article
Interest and use of hypnosis to improve physical and psychological well-being in oncology Cancer and its treatments have several consequences: pain, fatigue, sleep disturbances, nausea, vomiting, hot flashes, and emotional distress. These symptoms negatively affect patients’ quality of life and can persist for years after treatment completion. Desp...
Article
Background Patients' changing attitudes and beliefs about pain are considered as improvements in the treatment of chronic pain. Multidisciplinary approaches to pain allow modifications of coping strategies of patients, from passive to active. Methods We investigate how two therapeutic treatments impact patients' attitudes and beliefs regarding pai...
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This article summarizes key advances in hypnosis research during the past two decades, including (i) clinical research supporting the efficacy of hypnosis for managing a number of clinical symptoms and conditions, (ii) research supporting the role of various divisions in the anterior cingulate and prefrontal cortices in hypnotic responding, and (ii...
Article
Hypnosis has proved successful in a variety of clinical situations such as alleviation of acute or chronic pain and other chronic debilitating conditions (asthma-eczema). Many psychotherapists utilize imagery to facilitate the process of change, treating depression with hypnosis and integrating patient centered strategic approaches (challenge effic...
Article
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IntroductionRehabilitation in patients with severe brain injury remains a complex and challenging task. Published data about neurorehabilitative treatments are still insufficient to make clear recommendations. This report presents the case of a patient with severe brain injury for whom hypnosis was proposed as part of his rehabilitation treatment p...
Article
Introduction Interest in studying swallowing disorders in patients with altered consciousness has increased over the past decade. Swallowing deficit is frequently encountered in severe brain-injured patients. State of art Results of studies have highlighted different factors such as the delay between the injury and the treatment and the level of c...
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Cet article a pour objectif d’établir un « profil » des patients consultant pour des douleurs chroniques dans le service d’algologie du CHU de Liège en vue d’identifier des relations éventuelles entre des diagnostics, des états psychologiques et des modes de gestion de la douleur. Entre 2005 et 2010, 1 832 patients ont bénéficié d’une prise en char...
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Nous proposons de discuter des études comportementales, électrophysiologiques et de neuroimagerie investiguant l’hypnose comme un processus de conscience ou comme un outil pour moduler les réponses cérébrales au repos ou lors de stimulations douloureuses. Différentes études ont mis en évidence une modification de l’activité cérébrale au niveau des...
Article
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Depuis 2005, une politique d’amélioration de la prise en charge de la douleur chronique se met progressivement en place en Belgique. Trois types de structures existent actuellement: 73 fonctions algologiques, 36 équipes multidiscplinaires de la douleur chronique et neuf centres de référence multidisciplinaires de la douleur chronique. À la demande...
Article
Resting state fMRI (functional magnetic resonance imaging) acquisitions are characterized by low-frequency spontaneous activity in a default mode network (encompassing medial brain areas and linked to self-related processes) and an anticorrelated "extrinsic" system (encompassing lateral frontoparietal areas and modulated via external sensory stimul...
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Cette recherche a pour objectif de mettre à jour les différents facteurs invalidants ou favorisant la réintégration au travail et le maintien professionnel de patientes atteintes de deux types de maladies: la fibromyalgie ou la lombalgie chronique. En effet, les études actuelles sur la réinsertion et le maintien au travail sont généralement axées s...
Article
Ces dernières années, la littérature a démontré un intérêt croissant pour le concept de motivation dans l’éducation thérapeutique des patients souffrant de douleurs chroniques. Ainsi, de nombreux courants idéologiques ont abordé le concept de motivation mais aussi d’éducation thérapeutique tout en produisant de multiples théories et nouveaux savoir...
Article
Le syndrome douloureux régional complexe (SDRC) reste mal compris et difficile à traiter. Les critères de définition du IASP (International Association for the Study of Pain) de 1994 ont conduit à une surestimation de diagnostic. Une révision de ces critères a eu lieu en 2003 à Budapest permettant d’améliorer la spécificité de ces critères. Par ail...
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The neural mechanisms underlying the antinociceptive effects of hypnosis still remain unclear. Using a parametric single-trial thulium-YAG laser fMRI paradigm, we assessed changes in brain activation and connectivity related to the hypnotic state as compared to normal wakefulness in 13 healthy volunteers. Behaviorally, a difference in subjective ra...
Article
Euthanasia was legalized in Belgium in 2002 for adults under strict conditions. The patient must be in a medically futile condition and of constant and unbearable physical or mental suffering that cannot be alleviated, resulting from a serious and incurable disorder caused by illness or accident. Between 2005 and 2007, 4 patients (3 in Antwerp and...
Article
This short review describes recent advances in understanding hypnotic modulation of pain. Our current understanding of pain perception is followed by a critical review of the hypnotic analgesia studies using EEG, evoked potential and functional imaging methodologies. Copyright © 2008 British Society of Experimental & Clinical Hypnosis. Published by...
Article
Our understanding of the pathophysiologic mechanisms of chronic pain progresses; the complexity of the problem justifies our need for new molecules and new ways of administration that will help to further optimise and better individualize our pharmacologic therapies. Whereas acute pain can be considered an alarm signal, chronic pain constitutes, pe...
Article
Patients in a minimally conscious state (MCS) show restricted self or environment awareness but are unable to communicate consistently and reliably. Therefore, better understanding of cerebral noxious processing in these patients is of clinical, therapeutic, and ethical relevance. We studied brain activation induced by bilateral electrical stimulat...
Article
The origin of within-subject variability in perceptual experiments is poorly understood. We here review evidence that baseline brain activity in the areas involved in sensory perception predict subsequent variations in sensory awareness. We place these findings in light of recent findings on the architecture of spontaneous BOLD fluctuations in the...
Article
Improvement in functional neuroimaging allows researchers to disentangle the brain mechanisms involved in the pain modulation encountered during hypnosis. It has been shown that the anterior cingulate and prefrontal cortices are important in the modulation of incoming sensory and noxious input. Moreover, clinical studies in certain types of surgery...
Article
Pain is a subjective experience. Its assessment is based on the subject's direct verbal report. This method of assessment is, however, impossible in patients who cannot communicate their feelings. In this context, indirect measurements such as behavioral observations or physiological measurements are needed. To facilitate the assessment of pain in...
Article
Full-text available
The Locked-In syndrome (LIS) is defined by: (i) the presence of sustained eye opening (bilateral ptosis should be ruled out as a complicating factor); (ii) preserved awareness; (iii) aphonia or hypophonia; (iv) quadriplegia or quadriparesis; and (v) a primary mode of communication that uses vertical or lateral eye movement or blinking. Acute ventra...
Article
IntroductionThe Locked-In syndrome (LIS) is defined by: (i) the presence of sustained eye opening (bilateral ptosis should be ruled out as a complicating factor); (ii) preserved awareness; (iii) aphonia or hypophonia; (iv) quadriplegia or quadriparesis; and (v) a primary mode of communication that uses vertical or lateral eye movement or blinking....
Article
Introduction. – The Locked-In syndrome (LIS) is defined by: (i) the presence of sustained eye opening (bilateral ptosis should be ruled out as a complicating factor);(ii) preserved awareness; (iii) aphonia or hypophonia; (iv) quadriplegia or quadriparesis; and (v) a primary mode of communication that uses vertical or lateral eye movement or blinking...
Article
La complexité de la physiopathologie des douleurs neuropathiques permet de comprendre que seule une prise en charge multimodale (pharmacologique et non-pharmacologique) peut aider le patient à mieux gérer la problématique douleur et lui donner à nouveau une qualité de vie. L’acupuncture et l’hypnose comme d’autres approches psychologiques (cognitiv...
Article
Hypnotic-like behavior has been reported from the dawn of history. The early origins are shrouded in mystery and magic; but Franz Anton Mesmer, an Austrian physician, conducted his therapeutic sessions under the name of “animal magnestism”. He proposed a theory that the “magnetic” influence could be transfered by iron bars. However a committee of l...
Article
The purpose of our research is to contribute to a better understanding of the residual brain function of patients who survive an acute brain damage but remain in a coma, vegetative state, minimally conscious state or locked-in syndrome. The diagnosis, prognosis, therapy and medical management of these patients remain difficult. These studies are al...
Chapter
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Ein schwerer akuter Hirnschaden kann zu verschiedenen klinischen Daseinsformen führen, welche den Hirntod, das Koma, vegetative (VS), minimal bewusste (MCS) oder Locked-in (LIS)-Zustände umfassen. Einige dieser Zustände sind irreversibel, andere vorübergehend. Im Folgenden sollen die nosologischen Definitionen dieser klinischen Entitäten und ihre k...
Article
The neural mechanisms underlying hypnosis and especially the modulation of pain perception by hypnosis remain obscure. Using PET we first described the distribution of regional cerebral blood flow during the hypnotic state. Hypnosis relied on revivification of pleasant autobiographical memories and was compared to imaging autobiographical material...
Article
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A major challenge in the management of severely brain-injured patients with altered states of consciousness is to estimate their residual perception of the environment. To investigate the integrity of detection of one's own name in patients in a behaviorally well-documented vegetative state (VS), patients in a minimally conscious state (MCS), and p...
Article
This study assesses the influence of a muscular aerobic revalidation program on the management of the fibromyalgia syndrome. After 3 months, benefits consisting of increased muscle performances associated with a reduction of pain and an improvement of quality of life were documented. This study confirms the value of aerobic muscle exercise in fibro...
Article
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We review cerebral processing of auditory and noxious stimuli in minimally conscious state (MCS) and vegetative state (VS) patients. In contrast with limited brain activation found in VS patients, MCS patients show activation similar to controls in response to auditory, emotional and noxious stimuli. Despite an apparent clinical similarity between...
Article
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Nowadays, there is compelling evidence that there is a poor relationship between the incoming sensory input and the resulting pain sensation. Signals coming from the peripheral nervous system undergo a complex modulation by cognitive, affective, and motivational processes when they enter the central nervous system. Placebo- and hypnosis-induced ana...
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The locked-in syndrome (pseudocoma) describes patients who are awake and conscious but selectively deefferented, i.e., have no means of producing speech, limb or facial movements. Acute ventral pontine lesions are its most common cause. People with such brainstem lesions often remain comatose for some days or weeks, needing artificial respiration