Marianna Barbierik Vachalcová

Vychodoslovensky ústav srdcových a cievnych chorôb, a.s · Cardiology

Introduction Aortic valve replacement (AVR) is often recommended for patients with severe aortic stenosis or chronic aortic regurgitation. These conditions result in remodeling of the left ventricle, including increased interstitial fibrosis that may persist even after AVR. These structural changes impact left ventricular (LV) mechanics, causing co...

At the present time, right ventricular function in patients with aortic stenosis is insufficiently taken into account in the decision-making process of aortic valve replacement. The aim of our study was to evaluate significance of right ventricular dysfunction in patients with severe aortic stenosis by modern 3D echocardiographic methods. This is p...

Computed tomography 3D reconstruction of a patient with Bland-White-Garland syndrome showing a dilated right coronary artery and thin left coronary artery.

Significant acute cardiovascular, metabolic, and endocrine changes have been traced to short-lasting cold water immersion (CWI); however, the long-term impact of recurrent CWI on atherogenesis, lipid parameters, and fat distribution has not yet been studied. The goal of this study was to investigate the alleged protective effect. A total of 35 heal...

Objectives: The aim of this study was to investigate bleeding risk in patients treated with VKAs after ground-level falls, considering the type and severity of bleeding. Methods: The study was designed as a retrospective cohort study and included a total of 204 elderly patients aged > 65 years treated for AF continuously with warfarin for more t...

We present a case of a 31-year-old patient, smoker, with no previous medical history, presenting with acute limb ischemia and infarction of the spleen due to peripheral embolism. The source of embolism was thrombi formations in the left ventricular cavity, located in the area of the regional wall motions abnormalities. CT and coronary angiography c...

The gut microbiome is linked to the development of individual diseases. Patients with congestive heart failure (HF) develop intestinal wall edema due to venous congestion, which impairs absorption function and allows bacterial overgrowth. Consequently, the pathogenous bacterial strains produce many harmful substances, including trimethylamine N-oxi...

Abstract. Objectives: Severe symptomatic aortic stenosis is associated with worse prognosis. The aim of our study was to determine the relationship between the new echocardiographic parameter, left atrial coupling index (LACI) and standard clinical and echocardiographic parameters in patients with severe symptomatic aortic stenosis: at the same tim...

Objectives: We aimed to clarify the prognostic role of Total Serum Protein (TSP) in obese children with HFpEF and its using as an effective and noninvasive approach for screening of target population. Methods: In total, 587 patients who enrolled in our unique program aimed for children’s obesity treatment were referred. Among these patients, we ide...

Background: Atrial fibrillation (AF) is associated with high risk of stroke preventable by timely initiation of anticoagulation. Currently available screening tools based on ECG are not optimal due to inconvenience and high costs. Aim of this study was to study the diagnostic value of apelin for AF in patients with high risk of stroke. Methods: We...

Background Intermediate type atrioventricular septal defect is less frequent than complete or partial atrioventricular septal defect, and is rarely encountered in the elderly and the utility of three dimensional transesophageal echocardiography in the diagnosis has not been reported to date. Case presentation In this case report, we described a ra...

Non‐iatrogenic left atrial wall dissection is a rare lesion defined as a gap from the mitral valve annulus to the interatrial septum or wall of the left atrium. We report the case of a 57‐year‐old man with symptoms of acute cardiac and renal failure. Trans‐esophageal echocardiography and computed tomography showed significant mitral valve regurgita...

Background: Primary and secondary aortopathy are frequently encountered in patients with congenital heart disease. The aim of this study is to present our experience and the incidence of primary and secondary adult CHD-associated aortopathy. Methods: The cohort is comprised of adult patients with congenital heart disease from the registry of the...

Aims The aim of this pilot study was to compare selected three‐dimensional speckle tracking echocardiography (3D STE) parameters in patients with ischaemic and non‐ischaemic aetiology of heart failure (HF) and to identify indices that can differentiate the two pathologies. Methods and results Forty patients with left ventricular ejection fractio...

Background: Primary and secondary aortopathy are frequently encountered in patients with congenital heart disease. The aim of this study is to present our experience and the incidence of primary and secondary adult CHD-associated aortopathy. Methods. The cohort is comprised of adult patients with congenital heart disease from the registry of the Ea...

Background: Primary and secondary aortopathy are frequently encountered in patients with congenital heart disease. The aim of this study is to present our experience and the incidence of primary and secondary adult CHD-associated aortopathy. Methods. The cohort is comprised of adult patients with congenital heart disease from the registry of the Ea...

Micro ribonucleic acids (miRNAs) are short non-coding RNA molecules responsible for regulation of gene expression. They are involved in many pathophysiological processes of a wide spectrum of diseases. Recent studies showed their involvement in atrial fibrillation. They seem to become potential screening biomarkers for atrial fibrillation and even...

Background: Previous studies showed an association between apelin and atrial fibrillation (AF). The aim of this study was to analyse the effect of pulmonary vein isolation (PVI) in patients with paroxysmal AF on plasmatic apelin concentrations. Methods: Nine consecutive patients (aged from 43 to 69 years, 3 females and 6 males) with documented p...

Background The left atrial appendage (LAA) strain and strain rate have not yet been studied in the prediction of cardiac thromboembolism. Therefore, this study aimed to evaluate the significance of LAA strain and strain rate as assessed by speckle-tracking imaging in relation to documented thromboembolic events. Methods A group of 80 patients with...

Background: The aim of this prospective study was to investigate the prediction of all-cause mortality from global longitudinal strain (GLS) in two groups of chronic kidney disease patients (CKD): predialysis and dialysis. Methods: In 89 patients undergoing echocardiography, 37.2 % predialysis (16/43) and 58.6 % dialysis patients (27/46) died du...

The MitralClip (MC) is used for intervention therapy in serious mitral regurgitation. It is a metal implant with two arms, aimed at joining together the middle scallops of the mitral valve cusps and thus reduce the mitral mouth area, and thereby also the serious nature of mitral regurgitation. Surgery treatment of patients with isolated serious fun...

Transcatheter aortic valve implantation (TAVI) is an interventional method for the treatment of severe aortic stenosis. TAVI is indicated in patients who have been identified by the heart team as surgically inoperable or operable at very high risk. The advantage is minimal invasive approach with the absence of sternotomy and extracorporeal blood ci...

Nowadays, there is an attempt to diagnose subclinical myocardial damage, so allowing early intervention and prevention of its progression to heart failure. Speckle-tracking echocardiography (STE) appears to be a promising method of meeting these criteria and its prognostic value has been confirmed in several clinical trials. Two-dimensional myocard...

Introduction: Cardiovascular disease is the major cause of morbidity and mortality in patients with advanced chronic kidney disease (CKD). In the last decade a growing number of cardiac biomarkers have been identified as risk factors linked to adverse cardiovascular outcomes in patients with renal failure. Moreover, several cardiac structural abnor...

There is a need to assess the right ventricle in the diagnosis of chronic heart failure, because its function is proved to be an important indicator of prognosis, exercise tolerance and quality of life for the failure of the left ventricle. Aims: The target was to investigate the relationship between systolic dysfunction of the left ventricle (LV)...