María V Villa

• University of Salamanca

Sulfonamides derived from 8-aminoquinoline react with Mn(II) and Mn(III) salts to form Mn(II) complexes; the Mn(III) species are reduced to the divalent state in the presence of 1,10 phenanthroline and bipyridine. Their molecular structure, determined by single crystal X-ray diffraction, show that all the complexes present a distorted octahedral ge...

Three new coordination compounds have been prepared by reacting copper salts with sulfonamides derived from amino acids. Their molecular structures have been determined with the aid of single crystal X-ray diffraction. The copper cations are four-coordinated in all cases and the local environment is almost planar. Compound [Cu(ts-gly)(NH3)2]·H2O (1...

New copper(II) complexes with sulfonamide ligands have been prepared and characterized. Sulfonamide ligands were prepared through a reaction between 8-aminoquinoline and either 2-mesitylene (Hqmesa), 4-tert-butylbenzene (Hqtbsa), or alpha-toluene (Halphaqtsa) sulfonyl chlorides. The structural analysis carried out for complex [Cu(alphaqtsa)(2)] ind...

Reaction between 2-picolylamine (2-aminomethylpyridine) with 2-mesitylenesulfonyl and 4-tert-butylbenzene sulfonyl chlorides leads to the formation of 2,4,6-trimethyl-N-[pyridin-2-ilmethyl]benzenesulfonamide (Hpmesa) and 4-ter-butyl-N-[pyridin-2-ilmethyl]benzenesulfonamide (Hptbsa). These compounds react with Cu(II) salts to yield coordination comp...

Reaction between benzoguanamine (2,4-diamino-6-phenyl-1,3,5-triazine) and 2-mesitylenesulfonyl chloride leads to formation of a sulfonamide able to form two mononuclear Cu(II) complexes with a CuL(2) stoichiometry. The local environment of the metal cation is a distorted octahedron, with two ligands and two solvent molecules; both complexes crystal...

Mixed copper complexes have been synthetised through reaction of Cu(II) salts with bipyridil and N -quinolin-8-yl-p -toluenesulfonamide (Hqtsa), N -quinolin-8-yl-benzenesulfonamide (Hqbsa) or N -quinolin-8-yl-naftalenesulfonamide (Hqnsa). Single crystal X-ray diffraction structure determination shows that copper cations are five-coordinated, one co...

Mixed coordination compounds of Cu(II) with sulfonamides and 1,10-phenanthroline as ligands have been prepared and characterised. Single crystal structural determination of the complex [Cu(N-quinolin-8-yl-p-toluenesulfonamidate)(2)(phen)] shows Cu(II) ions are located in a highly distorted octahedral environment, probably as a consequence of the Ja...

Sulfonamides obtained by reaction of 8-aminoquinoline with benzenesulfonyl, toluene-4-sulfonyl and naphthalene-2-sulfonyl chlorides have been used to synthetize coordination compounds with ZnII with a ZnL2 composition. Determination of the crystal structures for the resulting complexes by X-ray diffraction shows a distorted tetrahedral environment...

N-Quinolin-8-yl-benzenesulfonamide (Hqbsa) and N-quinolin-8-yl-naftalenesulfonamide (Hqnsa) have been synthetized and physicochemically characterized, and used as ligands to coordinate copper complexes with ML2 stoichiometry. The structure of the compounds [Cu(qbsa)2]·DMF and [Cu(qnsa)2] has been determined by X-ray diffraction and both of them cry...

Ofloxacin (oflo) is able to interact with Co(II) and Zn(II) salts to form complexes with the general formula [M(oflo)(2)]. 4H(2)O, (M = Co, Zn). Bonding takes place through one of the oxygen atoms of the carboxylate group (acting as a monodentate) and the oxygen atom of the ketonic group. The IR bands of the carboxylic and ketonic group at 1713 and...

Reaction of Cu(II) salts with dithiocarbamates derived from the amino acids asparagine, glutamine, serine, threonine and tyrosine leads to reduction of the metallic cation and formation of Cu(I) complexes, whereas reaction with proline dithiocarbamate takes place without reduction, leading to formation of a Cu(II) coordination compound. Simultaneou...

Reaction between 8-aminoquinoline and benzenesulfonyl, toluene-4-sulfonyl and naphthalene-2-sulfonyl chlorides in a basic medium leads to the formation of the corresponding sulfonamides. Reaction of these sulfonamides with Ni(II) salts leads to the formation of the corresponding complexes, with a NiL2 stoichiometry. Determination of the crystalline...

A new copper complex with N-quinolin-8-yl-p-toulenesulfonamide has been prepared and characterised. The compound crystallises in the triclinic system, space group P1, with a=13.457(3), b=15.067(5), c=18.589(3) A; alpha=112.05(2), beta=93.92(2), gamma=108.30(2) degrees and Z=4. The geometry of the Cu(II) ion is distorted square planar. The N-quinoli...

Several coordination compounds formed between Ni(II) or Cu(II) with ofloxacin have been synthesised and characterised. According to elemental chemical analysis and FT-IR spectroscopy data, direct reaction of Ni(II) and Cu(II) salts with ofloxacin leads to formation of precipitates for which mass spectrometry demonstrates their polymeric nature. How...

Several coordination compounds formed between Ni(II) or Cu(II) with ofloxacin have been synthesised and characterised. According to elemental chemical analysis and FT-IR spectroscopy data, direct reaction of Ni(II) and Cu(II) salts with ofloxacin leads to formation of precipitates for which mass spectrometry demonstrates their polymeric nature. How...

Factor V and prothrombin-gene mutations are independent risk factors for venous thrombosis; it is debated whether a mutation in the gene encoding methylenetetrahydrofolate reductase, an enzyme involved in homocysteine metabolism, also increases the risk of venous thrombosis. Whether any of these mutations is associated with an increased risk of lat...

Dithiocarbamates (dtc's) derived from aspartic (asp) and glutamic (glu) acids have been synthesized and characterized. Their Ba salts are of the general formula Ba3(dtc–aa)2, where aa = amino acid. The dithiocarbamates react with NiII salts to yield square-planar complexes, [Ni(dtc–aa)2]. Complexes with PbII and CdII, with formula [M3(dtc–aa)2], ar...

This paper reports on the adsorption of different organic pesticides by hydrotalcite, hydrotalcite heated to 500 degrees C and organo-hydrotalcite in aqueous medium by employing adsorption isotherms, and using X-ray diffraction and infrared spectroscopy techniques. The results suggest that the adsorption capacity of the different materials depends...

The reaction between proline and carbon disulfide in a basic medium yields the corresponding dithiocarbamate (hereafter dtc pro). Reaction of this compound with Na2MoO4 · 2H2O leads to formation of a coordination compound with the formula MoO2(dtc Hpro)2, while reaction with MoCl5 in an inert atmosphere leads to Mo2O4(dtc Hpro)4. Mo K XANES data ar...

Adsorption and the mechanism of adsorption of the herbicide glyphosate [N-(phosphonomethyl) glycine] by hydrotalcite (HT) and by hydrotalcite calcined at 500°C (HT500) was studied. The values of the Freundlich K constant of the adsorption isotherms and the distribution coefficients, Kd, depend on the pH of the adsorption system and vary between 55....

Dithiocarbamates of tryptophane (tryp), lysine (lys) and arginine (arg) have been synthetized by direct rection of the corresponding amino acid with carbon sulphide in a basic medium. Barium salts isolated had formulae Ba(dtc tryp), Ba3(dtc lys)2 and Ba3(dtc arg)2. These dithiocarbamates react with nickel(II) salts forming square-planar complexes....

Phenylglycine and phenylalanine react with CS2 in a basic medium to yield the corresponding dithiocarbamates, which react with Ni2+ and Cu2+ salts to form complexes of the general formula [Ni(dtc aa)2] and [Cu(dtc aa)], respectively (aa = amino acid). Both series of complexes are diamagnetic and were characterized by analytical and physico-chemical...

The reaction between dithiocarbamate derivatives of α-amino acids (glycine, alanine, α-amino-butyric acid, norvaline, valine, norleucine, leucine and isoleucine) and sodium molybdate in acid medium leads to the formation of molybdenum(V) complexes with the general formula [Mo2O3)dtc a.a.)4]·2H2O (a.a = amino acid). The complexes were characterized...

The thermal stability of compounds formed by dithiocarbamates prepared from several amino acids (glycine, alanine, α-aminobutyric acid, norvaline, valine, norleucine, isoleucine) with Ba2+, Pb2+ Cd2+, Mo4+ and Mo5+ has been studied. Owing to its larger ionic character, the barium derivatives decompose at higher temperatures than the other compounds...

Ionization energies of dithiocarbamate derivatives of α-amino acids (glycine, alanine, valine, leucine) have been determined by X-Ray Photoelectron Spectroscopy. The values determined increase as the side chain in these amino acids becomes longer, a fact probably related to the different donor ability of these radicals. A parallel effect has been a...

Complexes formed through reaction of dithiocarbamate derived from α-amino acids with molybdenum(V) chloride in an inert atmosphere have been synthesized. These same complexes have also been prepared by the reduction of sodium molybdate with dithionite in an acidic medium. Chemical analyses for the complexes indicate the general formula [Mo2O4(dtc a...

A study has been carried out in vitro on the chelating properties of several dithiocarbamates derived from α-amino acids (glycine, DL-alanine, DL-valine, DL-leucine, DL-isoleucine, and L-proline) against Pb(II) and Cd(II). The general formulae of the complexes obtained was M(dtc a.a.), where M = Pb(II), Cd(II), and (dtc a.a.) stands for the dithioc...