Maria Angelica Torres-Quintana

• Phd
• Professor (Associate) at University of Chile

Proyecto FONIS SA21I0117: Estimación de la ingesta promedio diaria de fluoruros en niños de 0 a 12 meses en la Región Metropolitana, Chile, 2022. INFORME FINAL N°1: RESULTADOS Y/O PRODUCTOS ESPERADOS DEL PROYECTO FONIS SA21I0117 Manuscrito titulado: Concentración de fluoruros en los alimentos consumidos con mayor frecuencia en los niños de 0 a 12 m...

Elevated free fatty acids (FFAs) impair beta cell function and reduce beta cell mass as a consequence of the lipotoxicity that occurs in type 2 diabetes (T2D). We previously reported that the membrane protein caveolin-1 (CAV1) sensitizes to palmitate-induced apoptosis in the beta pancreatic cell line MIN6. Thus, our hypothesis was that CAV1 knock-o...

These results demonstrate adverse effects such as bone damage of the mandibular condyle and asymmetry in functional dental wearing after unilateral BoNTA-induced masseter atrophy, in a mouse model.

Background Masseter muscle function influences mandibular bone homeostasis. As previously reported, bone resorption markers increased in the mouse mandibular condyle two days after masseter paralysis induced with botulinum toxin type A (BoNTA), followed by local bone loss. Objective This study aimed to evaluate the bone quality of both the mandibu...

These results demonstrate that the 3D bone microstructure of the mandibular condyle correlates with the masseter muscle mass in this mouse model. We conclude that BoNTA-induced masseter muscle atrophy reduces bone quality of the associated mandibular condyle.

Masseter muscle paralysis induced by botulinum toxin type A produces mandibular head bone loss in adult mice after 14 d.

To determine the effect of masseter muscle paralysis on the subchondral bone of mandibula rcondyle in a mouse model.

El síndrome de Sjögren (SS) es una enfermedad autoinmune, crónica e inflamatoria caracterizada por infiltración de células plasmáticas y linfocitos en las glándulas exocrinas, particularmente en las salivales y oculares. La patogénesis del SS está relacionada con factores inmunológicos, neurológicos, genéticos, virales y hormonales. La deficiente c...

Sjögreńs syndrome (SS) is an autoimmune, chronic and inflammatory disease characterized by infiltration of plasma cells and lymphocytes in the exocrine glands. The pathogenesis of SS is related to immune, neurological, genetic, viral and hormonal factors. Complications are related to glandular destruction and mucosal dryness. The poor quality and q...

Objective: To estimate the cost-effectiveness of mandibular two implants retained overdenture versus conventional complete prostheses, using a randomized controlled trial (RCT) in a Chilean Public Dental Clinic. Methods: This study was approved by the Local Ethics Committee, 76 patients were included in each treatment group and were followed up f...

Masticatory performance has been assessed with varying methods throughout last century. Some of them use natural food as a test material and some others use artificial components instead of food. There have also been proposed various systems of processing the crushed material, such as fractional sieving, spectrophotometric analysis, compressed air,...

El fenómeno de la remodelación ósea es fundamental tanto para ortodoncia como para la ortopedia dentofacial. Esta revisión clínica es sobre la relación de la actividad ósea desencadenada por las fuerzas ortodóncicas con diversos factores, como factores propios de los pacientes, moléculas producidas por tejidos enfermos, o drogas y nutrientes consum...

Bone remodeling is fundamental to orthodontics and dentofacial orthopedics.This clinically oriented overview relate bone responses to orthodontic forces with many factors. Molecules produced in various diseased tissues, or drugs and nutrients consumed regularly by patients, can reach the mechanically stressed paradental tissues through the circulat...

Odontology faces important ethical dilemmas: interaction patient-odontologist; access to dental health; consciousness about population's needs, among others. All of these attract discussion and have to be treated according to ethics. This paper wants to show that bioethics, as an open alternative based upon dialogue and comprehension of evidences,...

Ameloblastin and amelogenin are structural proteins present in the enamel matrix of developing teeth. Here we report the results of in situ hybridization analyses with DNA probes of ameloblastin and amelogenin expression in the mandibular first molars of ICR/Jcl mice from postnatal day 1 to day 15. Ameloblastin mRNA expression was observed in amelo...

To establish the normal dental development pattern of the ICR/Jcl strain of mouse, we analyzed a significant number of observations of the different developmental stages of the first mandibular molar, accurately recording the chronology of their daily embryonic development. Proliferation of the dental sheet began at day 12.5 in utero (E-12.5), the...

To establish the normal dental development pattern of the ICR/Jcl strain of mouse, we analyzed a significant number of observations of the different developmental stages of the first mandibular molar, accurately recording the chronology of their daily embryonic development. Proliferation of the dental sheet began at day 12.5 in utero (E-12.5), the...

Immunohistochemical studies using a polyclonal antibody, raised against the recombinant form of dentin matrix protein 1 (DMP1), show that DMP1 was detected mainly in odontoblasts in cultured mouse embryonic tooth germs. However, in restricted areas, DMP1 staining was also observed in secretory ameloblasts, in the stratum intermedium and stellate re...

Post-translational modification of enamel proteins is regulated by casein kinases (CK) and results in binding sites for calcium ions that subsequently play a key role during the initial stages of mineralization. Phosphorylation may also influence the secretion and extracellular organization of enamel proteins. Previous studies indicated that inosit...

Lanthanum nitrate was either perfused intravascularly or segments of mouse tooth were immersed in a fixative solution containing the tracer. The tracer deposits were examined in young (8-day-old) and older (8-week-old) mouse incisors and molars, demineralized or undemineralized. Lanthanum passed the distal junctional complex of odontoblasts and app...

To study the effects of impaired protein phosphorylation on dentine formation and mineralization, inositol hexasulphate, an intracellular type I and type II casein kinase inhibitor, was used in an in vitro organotypic culture system. Mandibular first molar tooth germs were dissected from 18-day-old mouse embryos and cultured for 11 days with and wi...