Maria Petropoulou

Maria Petropoulou
University Medical Center Freiburg · Institute of Medical Biometry and Statistics

MSc, PhD

About

13
Publications
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418
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Introduction
Maria Petropoulou currently works at the Institute of Medical Biometry and Statistics at Medical University of Freiburg. Maria does research in Meta-analysis, Network meta-analysis and Evidence Synthesis Methods.

Publications

Publications (13)
Preprint
Full-text available
Network meta-analysis (NMA) is widely used in evidence synthesis to estimate the effects of several competing interventions for a given clinical condition. One of the challenges is that it is not possible in disconnected networks. Component network meta-analysis (CNMA) allows technically 'reconnecting' a disconnected network with multicomponent int...
Article
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Background Randomized controlled trials (RCTs) and cohort studies are the most common study design types used to assess the treatment effects of medical interventions. To evaluate the agreement of effect estimates between bodies of evidence (BoE) from randomized controlled trials (RCTs) and cohort studies and to identify factors associated with dis...
Article
Full-text available
In a quantitative synthesis of studies via meta‐analysis, it is possible that some studies provide a markedly different relative treatment effect or have a large impact on the summary estimate and/or heterogeneity. Extreme study effects (outliers) can be detected visually with forest/funnel plots and by using statistical outlying detection methods....
Article
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Many healthcare interventions are complex, consisting of multiple, possibly interacting, components. Several methodological articles addressing complex interventions in the meta-analytical context have been published. We hereby provide an overview of methods used to evaluate the effects of complex interventions with meta-analytical models. We summa...
Article
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In this study, we collect and synthesize information on the health status of the refugee/migrant population in ten European countries in order to map refugee/migrant health needs. With this information, we identify areas of intervention and healthcare system strengthening to provide the basis for future health planning and effective healthcare prov...
Article
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Objective: To analyze and determine the comparative effectiveness of interventions targeting frailty prevention or treatment on frailty as a primary outcome and quality of life, cognition, depression, and adverse events as secondary outcomes. Design: Systematic review and network meta-analysis (NMA). Methods: Data sources-Relevant randomized c...
Article
Full-text available
In network meta‐analysis (NMA), treatments can be complex interventions, for example, some treatments may be combinations of others or of common components. In standard NMA, all existing (single or combined) treatments are different nodes in the network. However, sometimes an alternative model is of interest that utilizes the information that some...
Data
Supplementary materials for the manuscript entitled "Characteristics and knowledge synthesis approach for 456 network meta-analyses: A scoping review."
Article
When we synthesize research findings via meta-analysis, it is common to assume that the true underlying effect differs across studies. Total variability consists of the within-study and between-study variances (heterogeneity). There have been established measures, such as I2, to quantify the proportion of the total variation attributed to heterogen...
Article
Full-text available
BACKGROUND: Optimal analgesia for total knee arthroplasty remains challenging. Many modalities have been used, including peripheral nerve block, periarticular infiltration, and epidural analgesia. However, the relative efficacy of various modalities remains unknown. The authors aimed to quantify and rank order the efficacy of available analgesic mo...
Article
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After the publication of the original article [1], it came to the author's attention that one of the study's funding sources was omitted. A Canadian Institutes of Health Research Catalyst Grant (Grant # 342169) should have been acknowledged, so the Funding section of the article should have read as follows.
Article
Full-text available
Background Network meta-analysis (NMA) has become a popular method to compare more than two treatments. This scoping review aimed to explore the characteristics and methodological quality of knowledge synthesis approaches underlying the NMA process. We also aimed to assess the statistical methods applied using the Analysis subdomain of the ISPOR ch...
Article
Objective: To assess the characteristics and core statistical methodology specific to network meta-analyses (NMAs) in clinical research articles. Study design and setting: We searched Medline, Embase and the Cochrane Database of Systematic Reviews from inception until April 14, 2015 for NMAs of randomized controlled trials (RCTs) including at le...

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Projects

Project (1)
Project
COMPAR-EU is a Horizon2020 EU project that will contribute to bridging the gap between current knowledge and practice of self-management interventions. COMPAR-EU aims to identify, compare, and rank the most effective and cost-effective self-management interventions (SMIs) for adults in Europe suffering from one of the four high-priority chronic conditions: type 2 diabetes, obesity, chronic obstructive pulmonary disease, and heart failure. The project will provide support for policy-makers, guideline developers and professionals to make informed decisions on the adoption of the most suitable self-management interventions through an IT platform, featuring decision-making tools adapted to the needs of a wide range of end users (including researchers, patients, and industry).