María Teresa García-Valverde

University of Cordoba (Spain) | UCO · Department of Analytical Chemistry

Abstract Background Intravenous pharmacokinetics and oral bioavailability of cannabidiol (CBD) with different formulations have not been investigated in horses and may represent a starting point for clinical studies. Objectives To describe pharmacokinetics after intravenous and oral administrations with oil and micellar formulations and simulate d...

Cannabinoids are gaining attention in many sectors, including the pharmaceutical, nutraceutical, and cosmetic sectors. To date, several conventional and alternative techniques have been applied for Cannabis sativa L (C. sativa L.) extraction at the industrial scale. The conventional methods are liquid solvent extraction, including polar and non-pol...

The substantial increase in legalization and subsequent regulation of cannabis has intensified the control and analytical monitoring of cannabis products to assure sample quality and control the cannabinoid content of the crop. In this sense, the restriction on cultivating legal cannabis plants has been limited to 0.2–0.3% of Δ ⁹ -THC content, depe...

In-needle microextraction consists of the confinement of the sorbent, by coating or packing, inside a metallic needle. The size of the needles reduces the eluent requirements providing an efficient preconcentration of the analytes. In this work, hypodermic needles coated with polydopamine (PDA) are presented as microextraction devices to isolate si...

In the last decades, cannabinoids, the active constituents of Cannabis sativa L., have been attracting a strong interest, regarding the health effects associated with the use of Cannabis and Cannabis-derived products. The progressive legalization of this species in several countries has prompted an increasing concern about the characterization and...

The use of natural materials as substrates or sorptive phases is a key trend in sample preparation. In this article, the porous structure of wooden tips (WTs) is exploited to achieve their simple modification with a polyamide by the dip-coating technique. Nylon 6, which combines hydrophobic interactions and H-bonding, is used as coating for the ext...

Chromatographic separation improves method selectivity at the expense of analysis time. In this article, the use of a molecularly imprinted polymer (MIP) paper combined with direct infusion electrospray ionization tandem mass spectrometry (DI-ESI-MS/MS) in the selected reaction monitoring (SRM) mode is presented as an alternative to the classical w...

The use of natural materials as biosorbents or substrates for the removal of pollutants from environmental waters is an interesting approach in line with the Green Chemistry principles. This strategy minimizes environmental pollution, and it provides natural material residues with a new use before its final disposal. Heracleum Persicum stems are pr...

Cotton is a natural material with good mechanical and chemical properties. It presents a hydrophilic surface that must be modified by the introduction of appropriate groups, if semi-polar or non-polar analytes are intended to be isolated from an aqueous matrix. In this article, cotton is modified with ß-cyclodextrins, which presents a hydrophobic c...

The simplification of the analytical procedures, including cost-effective materials and detectors, is a current research trend. In this context, paper has been identified as a useful material thanks to its low price and high availability in different compositions (office, filter, chromatographic). Its porosity, flexibility, and planar geometry perm...

Paper-based analytical devices (PADs) have encountered a wealth of applications in recent years thanks to the numerous advantages of paper as a support. A silver nanoflower (AgNF) modified paper-based dual substrate for both surface-enhanced Raman spectroscopy (SERS) and ambient pressure paper spray mass spectrometry (PS-MS) was developed. AgNFs we...

A new planar sorptive phase based on the simple immobilization of polymeric ionic liquids on paper is proposed. The sorptive phase can develop hydrophobic or mixed-mode (combining hydrophobic and ion exchange) interactions with the target analytes. The polymer is prepared by the Radziszewski reaction, which takes place in aqueous media, and it has...

Green analytical chemistry principles aim to minimize the negative impact of analytical procedures in the environment, which can be considered both at close (to ensure the safety of the analysts) and global (to conserve our natural resources) levels. These principles suggest, among other guidelines, the reduction/minimization of the sample treatmen...

A new procedure for the functionalization of melamine sponge (MeS) with urea-formaldehyde (UF) co-oligomers is put forward. The procedure differs from the typical synthesis of the UF co-polymer, as it employs a base-catalyzed condensation step at certain concentrations of urea and formaldehyde. The produced melamine-urea-formaldehyde (MUF) sponge c...

This article describes a method for the modification of paper with single-wall carbon nanohorns (SWCNHs) to form stable suprastructures. The SWCNHs form stable dahlia-like aggregates in solution that are then self-assembled into superior structures if the solvent is evaporated. Dipping paper sections into a dispersion of SWCNHs leads to the formati...

The pollution of environmental resources is an issue of social concern worldwide. Chemistry is essential for the design of decontamination strategies and analytical approaches to detect and monitor the contamination. Sorptive materials are usually required in both approaches and green synthesis should be used to minimize their own environmental imp...

Mesofluidic Lab-on-a-Valve (LOV) platforms have been proven suitable to accommodate automatic micro-solid-phase extraction approaches (µSPE) with on-chip handling of micrometer bead materials in a fully disposable mode to prevent sample cross-contamination and pressure drop effects. The efficiency of the extraction process notably depends upon the...

In this article, carbon fibres (CFs) are presented as sorbent material for the dispersive micro-solid phase extraction of twelve chlorophenols from urine samples. CFs are synthesized by a reagentless and green procedure consisting of heating raw cotton, a natural precursor, at high temperature (400°C) in an inert atmosphere (Ar) during 2h. The resu...

Background: In this article, carbon coated titanium dioxide nanotubes (TiO2-NT@C) are employed for the determination of 5-hydroxyindole-3-acetic acid in urine by LC-MS/MS. Results: All the variables involved in the extraction have been studied and optimized in depth. The method has been analytically characterized on the basis of its linearity, a...

Titanium-dioxide nanotubes (TDNTs) are elongated nanomaterials with a large specific surface area and notable features, such as inertness, AND chemical and thermal stability. This overview focuses on the use of TDNTs as sorbents in sample preparation. After a brief introduction to their properties and structure, we describe the main routes of synth...

In this article, carbon coated titanium dioxide nanotubes (c-TNTs) have been synthesized. The synthesis of the bare TNTs (b-TNTs) using anatase as precursor and their coating with a caramel layer have been performed by simple and cheap hydrothermal processes. The final conversion of the caramel layer in a carbon coating has been accomplished by a t...