Margarita Kalamara

Margarita Kalamara
  • University of Dundee

About

11
Publications
2,255
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258
Citations
Current institution
University of Dundee

Publications

Publications (11)
Article
Full-text available
Bacteria engage in competitive interactions with neighbours that can either be of the same or different species. Multiple mechanisms are deployed to ensure the desired outcome and one tactic commonly implemented is the production of specialised metabolites. The Gram-positive bacterium Bacillus subtilis uses specialized metabolites as part of its in...
Preprint
Full-text available
Bacteria engage in competitive interactions with neighbours that can either be of the same or different species. Multiple mechanisms are deployed to ensure the desired outcome and one tactic commonly implemented is the production of specialised metabolites. The Gram-positive bacterium Bacillus subtilis uses specialised metabolites as part of its in...
Article
Full-text available
Bacteria are tiny organisms that we cannot see with our naked eye. In nature they live in social groups called biofilms. To build biofilms bacteria produce a sticky material that works like a glue, called the biofilm matrix, that helps the bacteria stick to each other and to surfaces. Although some types of biofilms can be harmful, a lot of biofilm...
Article
Full-text available
Bacteria can form dense communities called biofilms, where cells are embedded in a self-produced extracellular matrix. Exploiting competitive interactions between strains within the biofilm context can have potential applications in biological, medical, and industrial systems. By combining mathematical modelling with experimental assays, we reveal...
Article
Biofilms are communities of bacteria that are attached to a surface and surrounded by an extracellular matrix. The extracellular matrix protects the community from stressors in the environment, making biofilms robust. The Gram-positive soil bacterium Bacillus subtilis, particularly the isolate NCIB 3610, is widely used as a model for studying biofi...
Article
Full-text available
Bacteria produce specialised metabolites with a range of functions. In this issue of the Journal of Bacteriology Schoenborn et al. study the production and role of secondary metabolites during biofilm development and sporulation in Bacillus subtilis . Most metabolites studied are produced during differentiation and six are required for the developm...
Preprint
Full-text available
Bacteria typically form dense communities called biofilms, where cells are embedded in a self-produced extracellular matrix. Competitive interactions between strains within the biofilm context are studied due to their potential applications in biological, medical, and industrial systems. Combining mathematical modelling with experimental assays, we...
Preprint
Full-text available
Biofilms are communities of bacteria that are attached to a surface and surrounded by an extracellular matrix. The extracellular matrix protects the community from stressors in the environment, making biofilms robust. The Gram-positive soil bacterium Bacillus subtilis , particularly the isolate NCIB 3610, is widely used as a model for studying biof...
Article
Full-text available
Biofilm formation by Bacillus subtilis is a communal process that culminates in the formation of architecturally complex multicellular communities. Here we reveal that the transition of the biofilm into a nonexpanding phase constitutes a distinct step in the process of biofilm development. Using genetic analysis we show that B. subtilis strains lac...
Preprint
Full-text available
Biofilm formation by Bacillus subtilis is a communal process that culminates in the formation of architecturally complex multicellular communities. Here we reveal that the transition of the biofilm into a non-expanding phase constitutes a distinct step in the process of biofilm development. Using genetic analysis we show that B. subtilis strains la...
Article
Full-text available
Here we review the multiple mechanisms that the Gram‐positive bacterium Bacillus subtilis uses to allow it to communicate between cells and establish community structures. The modes of action that are used are highly varied and include routes that sense pheromone levels during quorum sensing and control gene regulation, the intimate coupling of cel...

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