Margaret J Sampson

Margaret J Sampson
Children's Hospital of Eastern Ontario · Library Services

PhD, MLIS

About

264
Publications
86,840
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69,922
Citations

Publications

Publications (264)
Article
Full-text available
Background Psychosocial factors predict recurrent injury and return to preinjury level of performance following orthopedic injury but are poorly understood following concussion. Current management protocols prioritize physical measures of recovery. Therefore, the objective of this study was to describe the psychosocial factors associated with retur...
Article
Full-text available
Objectives: The ideal crystalloid fluid bolus therapy for fluid resuscitation in children remains unclear, but pediatric data are limited. Administration of 0.9% saline has been associated with hyperchloremic metabolic acidosis and acute kidney injury. The primary objective of this systematic review was to compare the effect of balanced versus unb...
Article
Purpose: Our primary objective was to describe consent models used in Canadian-led adult and pediatric intensive care unit (ICU/PICU) randomized controlled trials (RCTs). Our secondary objectives were to determine the consent rate of ICU/PICU RCTs that did and did not use an alternate consent model to describe consent procedures. Source: Using s...
Article
Full-text available
Objective: We evaluated reporting completeness and transparency in randomised controlled trials (RCTs) conducted using administrative data based on 2021 CONSORT Extension for Trials Conducted Using Cohorts and Routinely Collected Data (CONSORT-ROUTINE) criteria. Study design and setting: MEDLINE and the Cochrane Methodology Register were searche...
Article
Objective To describe characteristics of randomised controlled trials (RCTs) conducted using electronic health records (EHRs), including completeness and transparency of reporting assessed against the 2021 CONSORT Extension for RCTs Conducted Using Cohorts and Routinely Collected Data (CONSORT-ROUTINE) criteria. Study design MEDLINE and Cochrane M...
Article
Objective Registries are important data sources for randomised controlled trials (RCTs), but reporting of how they are used may be inadequate. The objective was to describe the current adequacy of reporting of RCTs using registries. Study Design and Setting We used a database of trials using registries from a scoping review supporting the developm...
Article
Full-text available
Background Standard practice for conducting systematic reviews (SRs) is time consuming and involves the study team screening hundreds or thousands of citations. As the volume of medical literature grows, the citation set sizes and corresponding screening efforts increase. While larger team size and alternate screening methods have the potential to...
Article
Full-text available
Randomised controlled trials are increasingly conducted as embedded, nested, or using cohorts or routinely collected data, including registries, electronic health records, and administrative databases, to assess if participants are eligible for the trial and to facilitate recruitment, to deliver an embedded intervention, to collect trial outcome da...
Article
Full-text available
Background Accepted systematic review (SR) methodology requires citation screening by two reviewers to maximise retrieval of eligible studies. We hypothesized that records could be excluded by a single reviewer without loss of sensitivity in two conditions; the record was ineligible for multiple reasons, or the record was ineligible for one or more...
Article
Importance: A significant portion of neurology literature is published in general medicine journals. Despite this, a detailed examination of publication patterns of neurology articles in these journals has not yet been carried out. Objective: To examine the publication patterns of neurology articles in general medicine journals during a 10-year...
Article
Full-text available
Objectives Randomised controlled trials conducted using cohorts and routinely collected data, including registries, electronic health records and administrative databases, are increasingly used in healthcare intervention research. A Consolidated Standards of Reporting Trials (CONSORT) statement extension for trials conducted using cohorts and routi...
Article
Introduction Solutions like crowd screening and machine learning can assist systematic reviewers with heavy screening burdens but require training sets containing a mix of eligible and ineligible studies. This study explores using PubMed's Best Match algorithm to create small training sets containing at least five relevant studies. Methods Six sys...
Article
Objective We aimed to examine the risk of concussion in children with a previous history of concussion. Design Systematic review and meta-analysis. The primary outcome was number of children with and without a previous lifetime history of concussion who sustained a diagnosed concussion within each study period. Risk of bias was assessed using the...
Article
Background Decontaminating and re-using filtering facepiece respirators (FFRs) for healthcare workers is a potential solution to address inadequate FFR supply during a global pandemic. Aim The objective of this review was to synthesize existing data on the effectiveness and safety of using chemical disinfectants to decontaminate N95 FFRs. Methods...
Article
Background In pandemics such as COVID-19, shortages of personal protective equipment are common. One solution may be to decontaminate equipment such as facemasks for reuse. Aim To collect and synthesize existing information on decontamination of N95 filtering facepiece respirators (FFRs) using microwave and heat-based treatments, with special atte...
Article
Background The high demand for personal protective equipment during the novel coronavirus outbreak has prompted the need to develop strategies to conserve supply. Little is known regarding decontamination interventions to allow for surgical mask reuse. Aim Identify and synthesize data from original research evaluating interventions to decontaminat...
Article
Background Inadequate supply of filtering facepiece respirators (FFR) for healthcare workers during a pandemic such as the novel coronavirus outbreak (SARS-CoV-2) is a serious public health issue. Aim To synthesize existing data on the effectiveness of ultraviolet germicidal irradiation (UVGI) for N95 FFR decontamination. Methods Systematic revie...
Article
Full-text available
Background: For optimal health benefits, the Canadian 24-Hour Movement Guidelines for Children and Youth (aged 5-17 years) recommend an achievement of high levels of physical activity (≥60 min of moderate-to-vigorous physical activity), low levels of sedentary behaviour (≤2 h of recreational screen time), and sufficient sleep (9-11 h for children...
Preprint
During the COVID-19 pandemic, a shortage of personal protective equipment (PPE), namely surgical masks, N95 masks, and gowns, has been experienced by some hospitals and could be expected in others due to a rapidly increased need. The Centres for Disease Control and Prevention (CDC) specifically recommends N95 filtering facepiece respirators (FFRs)...
Preprint
Background: The high demand for personal protective equipment (PPE) during the novel coronavirus outbreak has created global shortages and prompted the need to develop strategies to conserve supply. Surgical mask PPE have a broad application of use in a pandemic setting, but little is known regarding decontamination interventions to allow for their...
Preprint
Background: Decontaminating and re-using filtering facepiece respirators (FFR) for healthcare workers is a potential solution to address inadequate FFR supply during a global pandemic.Aim: The objective of this review was to synthesize existing data on the effectiveness and safety of using chemical disinfectants to decontaminate N95 FFR. Methods: W...
Preprint
Background: In pandemic situations such as COVID-19, shortages of proper protective equipment are common. One solution may be to decontaminate equipment such as facemasks for reuse.Aim: The aim of this review was to collect and synthesize existing information on decontamination of N95 filtering facepiece respirators (FFRs) using microwave and heat-...
Preprint
As the global spread of novel coronavirus (SARS-CoV-2) escalates, the high demand for personal protective equipment (PPE) has created shortages of this equipment globally and prompted the need to ensure appropriate stewardship and develop strategies to conserve supply. Surgical masks have broad and commonplace applications as PPE, including in the...
Preprint
During the COVID-19 pandemic, a shortage of personal protective equipment (PPE), namely surgical masks, N95 masks, and gowns, has been experienced by some hospitals and could be expected in others due to a rapidly increased need. One method of addressing the shortage is to decontaminate and re-use PPE. The Centres for Disease Control (CDC) specific...
Preprint
Background: Inadequate supply of filtering facepiece respirators (FFR) for healthcare workers during a global pandemic such as the novel coronavirus outbreak (SARS-CoV-2) is a serious public health issue. Aim: The objective of this review was to synthesize existing data on the effectiveness of ultraviolet germicidal irradiation (UVGI) on N95 FFR de...
Preprint
During the COVID-19 pandemic, a shortage of PPE (namely surgical masks, N95 masks, and gowns) has been experienced by some hospitals and could be expected in others due to a rapidly increased need. One method of addressing the issue of PPE shortage is to decontaminate and re-use PPE. The CDC specifically recommends N95 filtering facepiece respirato...
Preprint
During the COVID-19 pandemic, a shortage of PPR (namely surgical masks, N95 masks, and gowns) has been experienced by some hospitals and could be expected in others due to a rapid increase need. One method of addressing the issue of PPE shortage is to decontaminate and re-use PPE. There are anecdotal reports and published literature evaluating the...
Article
Cardiac disease in children is associated with significant morbidity and mortality as well as increased health resource utilization. There is a perception that there is a paucity of high-quality studies, particularly randomized controlled trials (RCTs), in the field of pediatric cardiology. We sought to identify, examine, and map the range of RCTs...
Article
Full-text available
Background: Isotonic crystalloid fluid bolus therapy is used in critically ill children to restore or maintain hemodynamic stability. However, the ideal choice of crystalloid remains to be determined. The most easily available and most frequently used crystalloid is 0.9% saline, an unbalanced crystalloid, that has been associated with hyperchlorem...
Conference Paper
Objectives Systematic reviews (SRs) are often cited as the highest level of evidence available as they involve the identification and synthesis of published studies on a topic. Unfortunately, it is increasingly challenging for small teams to complete SR procedures in a reasonable time period, given the exponential rise in the volume of primary lite...
Article
There is substantial evidence that research studies reported in the scientific literature do not provide adequate information so that readers know exactly what was done and what was found. This problem has been addressed by the development of reporting guidelines which tell authors what should be reported and how it should be described. Many report...
Article
Full-text available
Background: Systematic reviews (SRs) are often cited as the highest level of evidence available as they involve the identification and synthesis of published studies on a topic. Unfortunately, it is increasingly challenging for small teams to complete SR procedures in a reasonable time period, given the exponential rise in the volume of primary li...
Article
Full-text available
We developed a reporting guideline to provide authors with guidance about what should be reported when writing a paper for publication in a scientific journal using a particular type of research design: the single-case experimental design. This report describes the methods used to develop the single-case reporting guideline in behavioural intervent...
Article
Full-text available
Background Randomized controlled trials (RCTs) are often complex and expensive to perform. Less than one third achieve planned recruitment targets, follow-up can be labor-intensive, and many have limited real-world generalizability. Designs for RCTs conducted using cohorts and routinely collected health data, including registries, electronic health...
Article
Full-text available
Introduction Randomised controlled trials (RCTs) conducted using cohorts and routinely collected health data, including registries, electronic health records and administrative databases, are increasingly used in healthcare intervention research. The development of an extension of the CONsolidated Standards of Reporting Trials (CONSORT) statement f...
Article
This systematic review examined the associations between sleep and brain functions and structures in children and adolescents aged 1-17 ys. Included studies (n = 24) were peer-reviewed and met the a priori determined population (apparently healthy children and adolescents aged 1 y to 17 ys), intervention/exposure/comparator (various sleep character...
Article
This study aims to: (1) conduct a systematic review of YouTube videos showing newborn infants undergoing blood tests and (2) ascertain the use of recommended pain treatment strategies and infant pain during the filmed blood test. The pain was assessed using: (1) Neonatal Facial Coding System (NFCS) scores before, during and following the procedure;...
Article
Full-text available
Introduction Preterm birth (PTB) at <37 weeks of gestation is the leading cause of perinatal morbidity and mortality in developed countries. The traditional approach has been based on the assumption that PTB is primarily a result of intrauterine infection, which triggers preterm labour and puts the newborn at risk of early onset sepsis (EOS). We ar...
Article
Full-text available
Correction: After publication of the article [1], it has been brought to our attention that an incorrect reference has been used in this article, both in the main body and additional file 2. The reference in question is #105 in the main body and #74 in additional file 2. Here it is cited as "Lindsay H, Brussoni M. Injuries and helmet use related t...
Article
Full-text available
Background Vitamin D deficiency (VDD) has been hypothesized not only to be common but also to represent a potentially modifiable risk factor for greater illness severity and clinical outcome during critical illness. The objective of this systematic review was to determine the frequency of VDD in pediatric critical illness and its association with c...
Article
Objective: To synthesize and describe parental expectations on how healthcare professionals should interact with them during a peripartum, antenatal consultation for extremely preterm infants. Study design: For this systematic literature review with textual narrative synthesis, we included studies that explored parental perspectives regarding th...
Article
Full-text available
Background: Given the rapid development during the early years (0-4 years), an understanding of the health implications of physical activity is needed. The purpose of this systematic review was to examine the relationships between objectively and subjectively measured physical activity and health indicators in the early years. Methods: Electronic...
Article
Full-text available
Background: The Canadian Society for Exercise Physiology convened representatives of national organizations, research experts, methodologists, stakeholders, and end-users who followed rigorous and transparent guideline development procedures to create the Canadian 24-Hour Movement Guidelines for the Early Years (0-4 years): An Integration of Physi...
Article
Full-text available
Background: The purpose of this systematic review was to examine the relationships between sedentary behaviour (SB) and health indicators in children aged 0 to 4 years, and to determine what doses of SB (i.e., duration, patterns [frequency, interruptions], and type) were associated with health indicators. Methods: Online databases were searched...
Article
Full-text available
Background: The objective of this systematic review was to examine for the first time the associations between sleep duration and a broad range of health indicators in children aged 0 to 4 years. Methods: Electronic databases were searched with no limits on date or study design. Included studies (published in English or French) were peer-reviewe...
Article
Full-text available
Background: Historically, medical students who are lesbian, gay, bisexual or transgendered (LGBT) report higher rates of social stress, depression, and anxiety, while LGBT patients have reported discrimination and poorer access to healthcare. Objective: The objectives of this study were: (1) to assess if medical students have perceived discriminati...