Marek Kanikowski

Background The purpose of this study is to determine the effect of the type of I-125 radioactive source on dose distribution in the planning process of ultra-low dose rate (uLDR) prostate brachytherapy. Material and methods 7 patients who had undergone brachytherapy in our center were included in the study. Dose in five geometrical points were ana...

The aim of this work was to evaluate outcomes after definitive high-dose-rate endobronchial brachytherapy (HDR-BT) for lung cancer. We treated 34 patients after surgery for lung cancer, without nodal or distant metastases, with HDR-BT. Two groups were analyzed, one with local recurrence in stump after prior surgery (n = 13) and a second with nonrad...

Comparison of selected parameters of dose and volume treated with HDR-TD in three fractionation schemes, taking into account the biological dose.

Background: Hyperthermia (HT) causes a direct damage to cancerous cells and/or sensitize them to radiotherapy with usually minimal injury to normal tissues. Adjuvant HT is probably one of the most effective radiation sensitizers known and works best when delivered simultaneously with radiation. In breast conserving therapy, irradiation has to mini...

Low-dose rate brachytherapy (LDR-BT) is a radiation method known for several years in the treatment of localized prostate cancer. The main idea of this method is to implant small radioactive seeds directly into the prostate gland. LDR brachytherapy is applied as a monotherapy and also used along with external beam radiation therapy (EBRT) as a boos...

Purpose The aim of this work was to analyze the results and complications of three treatment schemes of patients with initially localized prostate cancer after two years of observation time. Material and methods Sixty-three patients were enrolled into the study and divided into groups according to radiation schemes (I group – EBRT 50 Gy/BRT 15 Gy,...

Purpose The quality of HDR-BT of prostate cancer depends on operator skills, anatomy, prostate volume and relation to surrounding tissues as well as previous diseases and treatments of a patient. There is a rare data available concerning the minimum number of needles and its influence on dose distribution, side effects and long-term outcome. The st...

The aim of this work is to compare the results of various treatment protocols used in palliative HDRBT with the view of analyzing differences in survival and diminishing breathing difficulties. A total of 648 patients with advanced lung cancer were divided into two groups according to their clinical stage and the Zubrod-ECOG-WHO score. 303 (46.8%)...

Purpose: Certain constraints for target coverage and dose limits in Organs at Risk (OARs) shows some evidence that doses values and homogeneity index in treated volume depends on prognostic factors such as prostate volume, location of urethra and the number of inserted applicators. Our study is to determine the relation between values of the doses...

Purpose: In the study we present the initial results of palliative treatment using combined methods of HDR-BT and stent insertion in patients with advanced esophagus cancer. Material and methods: Fifty patients were treated in the Great Poland Cancer Center using HDR-BT between June 2001 and December 2005 and they were enrolled into the study. All...

Breast-conserving surgery (BCS) followed by radiotherapy (RT) has become the standard treatment for the majority of patients with early breast cancer. With regard to boost technique some disagreements are found between groups that are emphasizing the value of electron boost treatment and groups pointing out the value of interstitial brachytherapy (...

SUMMARY : Low-dose rate brachytherapy (LDR - BT) is one of the radiation methods that is known for several years in treatment of localized prostate cancer. The main idea of this method is to implant small radioac- tive seeds as a source of radiation, directly into the prostate gland. LDR brachytherapy is applied as a monotherapy and also used along...

Endobronchial obstruction associated with lung cancer represents a common and potentially life threatening complication of newly diagnosed or recurrent disease. The vast majority of patients with obstructive lesions are not curable so it is desirable to palliate these patients as quickly as possible without compromising quality of life. High dose r...

The aim of this paper is to give a concise description of hyperthermia and a brief review of its clinical applications. Hyperthermia (HT, thermal therapy) is thought to be one of the cancer therapies and is considered to be an artifi cial way of in-creasing the body tissue temperature by delivering heat obtained from external sources to destroy can...

Purpose: In the study we present the initial results of palliative treatment using combined methods of HDR-BT and stent insertion in patients with advanced esophagus cancer. Material and methods: Fifty patients were treated in the Great Poland Cancer Center using HDR-BT between June 2001 and December 2005 and they were enrolled into the study. All...

The study was performed in 1996-2003 on a group of 585 patients who underwent fiberoptic bronchoscopy because of primary lung cancer suspicion. A tentative diagnosis was made on the basis of the patient history and lesions identified in conventional chest X-ray pictures. Symptoms of the neoplasmatic disease were caused by infiltration of the respir...

There are many methods of snoring treatment from conservative and prosthetic to surgical. The snoring sound is produced by vibration of the soft tissues of the pharynx, soft palate and also uvula. Snoring occurs in 50% of the adult male population and it can be isolated or sign of the obstructive sleep apnoea syndrome. Oral appliances modify the po...

Low-dose rate brachytherapy (LDR -BT) is one of the radiation methods that is known for several years in treatment of localized prostate cancer. The main idea of this method is to implant small radioac-tive seeds as a source of radiation, directly into the prostate gland. LDR brachytherapy is applied as a monotherapy and also used along with extern...

Brachytherapy is one of the oldest methods in treatment of tumors known from the beginning of XX century. Generally the main idea of this method is to implant radioactive source and to provide radiation dose directly into the tumor mass. HDR brachytherapy (HDR – BT) in treatment of prostate cancer is most frequently used together with external beam...