Marek Bunse

• Dr. rer. nat.
• WALA Remedies GmbH

Essential oils (EOs) and their individual volatile organic constituents have been an inherent part of our civilization for thousands of years. They are widely used as fragrances in perfumes and cosmetics and contribute to a healthy diet, but also act as active ingredients of pharmaceutical products. Their antibacterial, antiviral, and anti-inflamma...

Two undescribed monodesmosidic oleanene-type saponins, namely 3β-O-{[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyl}-saikogenin G (1) and 3β-O-{[β-D-glucopyranosyl-(1→4)]-α-L-arabinopyranosyl}-16-deoxysaikogenin F (2), named anthylloside A and B, have been isolated from an acetone-water extract from aerial parts of kidney vetch (A. vulneraria L.)....

Preparations derived from roots and rhizomes of Geum urbanum L. are traditionally used for the treatment of ulcers and irritations of mucous membranes of the mouth, stomach, and intestinal tract. In complementary medicine, fermentation is one of the methods applied to recover plant extracts used for the production of such pharmaceutical preparation...

The present study aimed at the identification and quantitation of phenolic compounds, fatty acids, and further characteristic substances in the seeds of Geum urbanum L. and Geum rivale L. For this purpose, individual components of extracts recovered with MeOH, CH2Cl2, and by cold-pressing, respectively, were characterized by HPLC-DAD/ESI-MSn and GC...

Great burnet (Sanguisorba officinalis) has been used as medicinal plant for more than 2000 years. However, little is known about the morphology and the secondary metabolites of its seeds. The investigations reported here focus on the morphology and the characterization of phenolics and fatty acids in S. officinalis seeds. For this purpose, dried se...

In the present study, Achillea atrata L. and A. millefolium L. were compared for the first time with regard to their phenolic compound profile and antioxidant activity by applying the 2,2-diphenyl-picryl hydrazyl radical assay. For this purpose, aerial plant parts were consecutively extracted with solvents of increasing polarity (dichloromethane, n...

Zusammenfassung Der Große Wiesenknopf (Sanguisorba officinalis L.) – eine Pflanze aus der Familie der Rosaceae – findet seit über 2000 Jahren vorwiegend im chinesischen Raum Anwendung bei der Behandlung von Verbrennungen, Blutungen und schlecht heilenden Wunden. Hydroalkoholische Auszüge der Wurzeln werden heute insbesondere in der Komplementärmedi...

Front Cover. Kidney vetch (Anthyllis vulneraria L.) is an almost forgotten medicinal plant, which is gaining increasing demand as herbal raw material, potentially applicable in cosmetic or phytomedicinal preparations. Since studies providing a profound overview on A. vulneraria constituents are still scant, the particular focus of the full paper pr...

Kidney vetch (Anthyllis vulneraria L.) is an old medicinal plant ethnopharmaceutically used for the treatment of wounds and ulcerations. Nowadays extracts were mainly applied in cosmetics remedies due to there benefical effects on the skin. However, studies on the natural products composition are rare. Therefore, we comprehensively analyzed the pro...

Supporting Informations: "Characterization of Secondary Metabolites in Flowers of Sanguisorba officinalisL. by HPLC‐DAD‐MSn and GC/MS" https://doi.org/10.1002/cbdv.201900724

Extracts of kidney vetch ( Anthyllis vulneraria L.) are becoming increasingly interesting as ingredients for the health and cosmetics industry. However, comprehensive phytochemical investigations of this plant are scant in the literature. Thus, the aim of the present work was an in‐depth characterization of semi‐polar constituents from A. vulnerari...

The investigations reported here focus on an in-depth characterization of the secondary metabolite profile of Sanguisorba officinalis flowers. For this purpose, fresh flowers were extracted with MeOH/H2O and EtOH/H2O and the resulting crude extracts fractionated using CH2Cl2, AcOEt, and n-BuOH. Individual compounds were characterized by high perfor...

Microbial fermentation of plant extracts with Lactobacteria is an option to obtain microbiologically stable preparations, which may be applied in complementary medicine. We investigated the metabolic conversion of constituents from Mercurialis perennis L. extracts, which were prepared for such applications. For this purpose, aqueous extracts were i...

Zusammenfassung Hypericum-Samen wurden kürzlich als natürliche Quelle für eine Reihe von Xanthon-Derivaten beschrieben. In Methanol-Extrakten von H. perforatum und H. tetrapterum konnten per HPLC(DAD)-MS n zwei Hauptkomponenten, die Tetrahydroxyxanthone THX-1 und-2, identifiziert werden, deren genaue Konfiguration bislang unbekannt war. Beide Subst...

Seeds from Hypericum species have recently been identified as an interesting source of xanthone derivatives. Extraction of seeds from H. perforatum with MeOH and subsequent concentration via polyamide adsorption yielded a fraction enriched in tetrahydroxyxanthones (THX), which were further semipurified by silica chromatography. Based on tentative s...