Marco Curto

University of Portsmouth · Faculty of Technology

In regenerative medicine, 3D scaffolds are used to sustain the regeneration of tissues in removed or damaged parts of the human body. As such practices are being widely experimented in clinical applications, the design, the materials and the manufacturing process to obtain efficient 3D biocompatible lattices are being significantly investigated. Ne...

The aim of regenerative medicine is replacing missing or damaged bone tissues with synthetic grafts based on porous interconnected scaffolds, which allow adhesion, growth, and proliferation of the human cells. The optimal design of such scaffolds, in the Bone Tissue Engineering field, should meet several geometrical requirements. First, they have t...

Cortical bone is an example of a mineralized tissue containing a compositional distribution of hard and soft phases in 3-dimensional space for mechanical function. X-ray computed tomography (XCT) is able to describe this compositional and morphological complexity but methods to provide a physical output with comparable mechanical function is lackin...

The purpose of this work is the morphological.11 characterization of a Voronoi-based biomimetic bone scaffold, developed through an interactive generative design process and obtained by an additive manufacturing system. In particular, the assessment of its characteristics was carried out according to the main indices of trabecular bone structures....

Combination of micro-focus computed tomography (micro-CT) in conjunction with in situ mechanical testing and digital volume correlation (DVC) can be used to access the internal deformation of materials and structures. DVC has been exploited over the past decade to measure complex deformation fields within biological tissues and bone-biomaterial sys...

The goal of this study was to determine whether a bio-based self-reinforced polylactic acid (SRPLA) is suitable for use in structures deployed in the marine environment. The material was produced from co-mingled fibres with different melting points. Two key criteria, durability during service and microplastic formation, were examined. To assess dur...

There is a growing interest in replacing fossil-based polymers and composites with more sustainable and renewable fully biobased composite materials in automotive, aerospace and marine applications. There is an effort to develop components with a reduced carbon footprint and environmental impact, and materials based on biocomposites could provide s...

Additive Manufacturing (AM) often produces complex engineered structures by precisely distributing materials in a layer-by-layer fashion. Multimaterial AM is a particularly flexible technique able to combine a range of hard and soft materials to produce designed composites. Critically, the design of AM multimaterial structures requires the developm...

Digital Volume Correlation (DVC) has become popular for measuring the strain distribution inside bone structures. A number of methodological questions are still open: the reliability of DVC to investigate augmented bone tissue, the variability of the errors between different specimens of the same type, the distribution of measurement errors inside...