Marco Calabria

Marco Calabria
Universitat Oberta de Catalunya | UOC · Health Sciences Studies

Professor

About

72
Publications
19,682
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2,243
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Introduction
I am a Professor of Neuropsychology at the Faculty of Health Sciences at the Universitat Oberta de Catalunya in Barcelona. Previously, he has been working at the Center for Brain and Cognition at the Pompeu Fabra University. My research interests are: a) lexico-semantic deficits in bilingual speakers and b) bilingualism as a mechanism of cognitive reserve, and c) bilingual language control in healthy individuals and neurodegenerative diseases.
Additional affiliations
June 2009 - October 2019
University Pompeu Fabra
Position
  • Fellow

Publications

Publications (72)
Article
Full-text available
Fatigue in its many forms of physical, mental, and psychosocial exhaustion is a common symptom of post-COVID-19 condition, also known as “Long COVID.” Persistent fatigue in COVID-19 patients is frequently accompanied by cognitive dysfunction and neuropsychiatric symptoms; however, less is known about the relationships between these components of po...
Article
Full-text available
Background While much of the scientific focus thus far has been on cognitive sequelae in patients with severe COVID‐19, subjective cognitive complaints are being reported across the spectrum of disease severity, with recent studies beginning to corroborate patients’ perceived deficits. In response to this, the aims of this study were to (1) explore...
Article
Background: Previous studies have argued that there are two types of linguistic gender: grammatical gender, which is arbitrarily assigned to nouns, and semantic gender, which depends on the gender of the referent. Aim: We explore the hypothesis that these two types of gender entail distinct cognitive processes by investigating the performance of pe...
Poster
Full-text available
Objetivos: Replicar hallazgos previos del perfil cognitivo pre/posten pacientes con EP intervenidos mediante ECP-NST yestudiar la posible influencia del bilingüismo sobre el rendimiento en tareas de fluencia verbal y otras medidas neuropsicológicas
Preprint
Full-text available
Background. Previous studies have argued that two types of linguistic gender exist: grammatical gender, which is arbitrarily assigned to nouns, and semantic gender, which depends on the gender of the referent. Aim. We explore the hypothesis that these two types of gender entail distinct cognitive processes by investigating the performance of people...
Article
In the present study, we explored the underlying mechanisms of lexical retrieval in two languages when modulated by phonological context. To do so, we investigated the performance of bilingual patients with aphasia and healthy bilingual individuals on a blocked cyclic naming task as a measure of lexical activation and phonological encoding within t...
Article
Full-text available
As studies of bilingual language control (BLC) seek to explore the underpinnings of bilinguals' abilities to juggle two languages, different types of language switching tasks have been used to uncover switching and mixing effects and thereby reveal what proactive and reactive control mechanisms are involved in language switching. Voluntary language...
Article
Full-text available
Lifelong bilingualism may contribute to cognitive reserve (CR) in neurodegenerative diseases as shown by a delay of the age at symptom onset in bilinguals with Alzheimer’s disease (AD) and Mild Cognitive Impairment (MCI). However, some studies have failed to show this bilingual advantage, suggesting that it might depend on the type and degree of bi...
Article
Full-text available
Background: Evidence from previous studies suggests that bilingualism contributes to cognitive reserve because bilinguals manifest the first symptoms of Alzheimer's disease (AD) up to 5 years later than monolinguals. Other cross-sectional studies demonstrate that bilinguals show greater amounts of brain atrophy and hypometabolism than monolinguals...
Article
Full-text available
Background: Patients with the semantic variant of Primary Progressive Aphasia (svPPA) offer a unique opportunity to study the relationship between lexical retrieval and semantics, as they are characterised by progressive degradation of central semantic representations. However, there are few studies of how lexical retrieval across languages is affe...
Article
Full-text available
Individuals with aphasia frequently show lexical retrieval deficits due to increased interference of semantically related competitors, a phenomenon that can be observed in tasks such as naming pictures grouped by semantic category. These deficits are explained in terms of impaired semantic control, a set of abilities that are to some extent depende...
Preprint
Full-text available
This study investigates the relationship between mechanisms involved in language control within dual- and single-language contexts by examining whether they are similarly impaired in bilingual PD patients. To do so, we explored the performance of bilingual individuals affected by PD and healthy controls on two linguistic tasks: between-language and...
Article
Full-text available
The present study investigated language inhibition and cross-language interference as two possible mechanisms of bilingual language control (BLC) that can be affected by Huntington’s disease (HD), a neurodegenerative disease (ND) affecting the striatum. To this aim, the study explored the performance of pre-symptomatic and early-stage HD patients i...
Article
Full-text available
What is the relationship between bilingual language control (BLC) mechanisms and domain-general executive control (EC) processes? Do these two domains share some of their mechanisms? Here, we take a novel approach to this question, investigating whether short-term language switching training improves non-linguistic task switching performance. Two g...
Article
Full-text available
Acquiring and speaking a second language increases demand on the processes of language control for bilingual as compared to monolingual speakers. Language control for bilingual speakers involves the ability to keep the two languages separated to avoid interference and to select one language or the other in a given conversational context. This abili...
Article
Full-text available
Bilingual speakers are suggested to use control processes to avoid linguistic interference from the unintended language. It is debated whether these bilingual language control (BLC) processes are an instantiation of the more domain-general executive control (EC) processes. Previous studies inconsistently report correlations between measures of ling...
Article
We investigated whether it is possible to study the network dynamics and the anatomical regions involved in the earliest moments of picture naming by using invasive electroencephalogram (EEG) traces to predict naming errors. Four right-handed participants with focal epilepsy explored with extensive stereotactic implant montages that recorded tempor...
Article
Full-text available
Here we investigated how the language in which a person addresses us, native or foreign, influences subsequent face recognition. In an old/new paradigm, we explored the behavioral and electrophysiological activity associated with face recognition memory. Participants were first presented with faces accompanied by voices speaking either in their nat...
Article
In one task-switching experiment, we compared bilinguals and monolinguals to explore the reliability of the bilingualism effect on the n-2 repetition cost. In a second task-switching experiment, we tested another group of bilinguals and monolinguals and measured both the n-1 shift cost and the n-2 repetition cost to test the hypothesis that bilingu...
Article
We explored the overlap between bilingual language control (bLC) and domain-general executive control (EC) by focusing on inhibitory control processes. We tested 62 bilinguals in linguistic and non-linguistic switching tasks for two types of costs, such as the n-1 shift cost and the n-2 repetition cost. In order to explore the involvement of inhibi...
Conference Paper
The understanding of the nature of the control abilities in the context of bilingual language production is now a hot research topic. Indeed, the improvement of our knowledge about this issue would offer the possibility to explain the patterns of language impairments in terms of control deficits. One way to look at this is to investigate the intera...
Article
At the outset of her article Valian (2014) advocates for the existence of an effect of bilingualism on executive control (EC). She is commended for being very clear about her position. She argues that: "There is a benefit of bilingualism for executive function, but that benefit competes with other benefits that both mono- and bilinguals have to var...
Article
Full-text available
Spatial neglect is a neurological condition characterised by deficits for perceiving, attending, representing, and/or performing actions within their left- sided space, responsible for numerous debilitating effects in everyday life, for poor functional recovery, and for decreased ability to benefit from treatment. Exposure to a right lateral displa...
Article
The basal ganglia are critically involved in language control (LC) processes, allowing a bilingual to utter correctly in one language without interference from the non-requested language. It has been hypothesized that the neural mechanism of LC closely resembles domain-general executive control (EC). The purpose of the present study is to investiga...
Article
Full-text available
Bilingual speakers are usually quite good at restricting their lexicalization output to the desired language while preventing all sorts of language intrusions from the language not in use. However, brain damage can affect these abilities of language control, leading to striking and flagrant linguistic behaviours, such as pathological language mixin...
Article
Full-text available
The aim of the present study is two-fold. First, we investigate age-related changes to bilingual language control (bLC) mechanisms across lifespan. Second, we explore the relation between bLC mechanisms and those of the domain-general executive (EC) system by looking at age effects on these two systems. To do so, we compare the performances of the...
Article
Full-text available
In this article we aimed to assess how Alzheimer's disease (AD), which is neurodegenerative, affects the linguistic performance of early, high-proficient bilinguals in their two languages. To this end, we compared the Picture Naming and Word Translation performances of two groups of AD patients varying in disease progression (Mild and Moderate) wit...
Article
Full-text available
Several studies have documented the advantage of bilingualism with respect to the development of the executive control (EC) system. Two effects of bilingualism have been described in conflict resolution tasks: (a) bilinguals tend to perform the tasks faster overall, and (b) bilinguals tend to experience less interference from conflicting informatio...
Article
Full-text available
In patients with cognitive deficits, brain stimulation has been shown to restore cognition (Miniussi et al., 200810. Miniussi , C. , Cappa , S. F. , Cohen , L. G. , Floel , A. , Fregni , F. Nitsche , M. A. 2008. Efficacy of repetitive transcranial magnetic stimulation/transcranial direct current stimulation in cognitive neurorehabilitation. B...
Article
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Repetitive transcranial magnetic stimulation (rTMS) has been proposed as a possible treatment for the cognitive deficits associated with Alzheimer disease (AD). The aim of this study was to assess the long-term effects, on cognitive performance, of rTMS applied to the left dorsolateral prefrontal cortex (DLPFC) in AD patients. Ten AD patients were...
Article
Full-text available
It has been proposed that time, space, and numbers share the same metrics and cortical network, the right parietal cortex. Several recent investigations have demonstrated that the mental number line representation is distorted in neglect patients. The aim of this study is to investigate the relationship between time and spatial configuration in neg...
Article
Full-text available
Growing interest in understanding the relationship between subjective memory complaints (SMCs) and objective measures of memory abilities emphasizes the importance of SMC assessment for diagnostic purposes. The present study investigated the relationship between SMCs and objective memory deficits in elderly adults by analysis of the factor structur...
Article
Full-text available
Previous research has shown that highly proficient bilinguals have comparable switch costs in both directions when they switch between languages (L1 and L2), the so-called "symmetrical switch cost" effect. Interestingly, the same symmetry is also present when they switch between L1 and a much weaker L3. These findings suggest that highly proficient...
Article
Full-text available
Word-retrieval difficulties commonly occur in healthy aging. Recent studies report an improved ability to name pictures after the administration of high-frequency repetitive transcranial magnetic stimulation (rTMS) in healthy younger adults and in patients with neurological disease. The aim of this study was to assess the effect of high-frequency...
Article
The ability to associate a name to a face is a crucially relevant task in daily life. In this study, we investigated the neuronal basis of face-name retrieval in young subjects using repetitive transcranial magnetic stimulation (rTMS) over the left or right dorsolateral prefrontal cortex (DLPFC). The experimental task was composed of two study phas...
Article
Repetition priming (RP) has been employed as a measure of implicit processing in patients suffering from a breakdown of semantic memory, as in the case of semantic dementia (SD), a subtype of frontotemporal lobar degeneration (FTLD). Here, we investigated face-name representation in a case of SD using a paradigm of within- and cross-domain repetiti...
Article
Recent studies have demonstrated that patients suffering from frontotemporal lobar degeneration (FTLD) show impairments in empathy and emotional processing. In this study, we examined two different aspects of these abilities in a patient with semantic dementia (SD), a variant of FTLD. The first aspect was the assessment of the cognitive and emotion...
Article
We evaluated changes of brain rhythmicity correlating with the cerebrovascular damage of long-range (capsular tract) and short-range (medial and perisylvian tracts) cholinergic pathways in subjects with mild cognitive impairment (MCI). Ninety-four MCI subjects underwent electroencephalographic (EEG) recordings and magnetic resonance imaging (MRI)....
Article
Long-term efficacy of acetyl-cholinesterase-inhibitor (ACHEI) treatment in mild-to-moderate Alzheimer's disease (AD) is of great relevance for clinical routine and has been investigated over a 21-month period of treatment in a "real word" population. We investigated cognitive (mini mental state examination=MMSE) and functional (instrumental activit...
Article
Introduction: While sentence comprehension has been reported to be defective in frontotemporal dementia (FTD), it is still unclear if this disorder reflects the presence of syntactic impairment, or may be attributed to other factors, such as executive or working memory dysfunction. In order to assess the status of syntactic knowledge in a group of...
Article
Frontotemporal lobar degeneration (FTLD) includes different heterogeneous conditions mainly characterized by personality changes and cognitive deficits in language and executive functions; movement disorders have also been associated with FTLD. The present study aimed to measure the primary motor cortex (M1) inhibitory and facilitatory functions in...
Article
While sentence comprehension has been reported to be defective in frontotemporal dementia (FTD), it is still unclear if this disorder reflects the presence of syntactic impairment, or may be attributed to other factors, such as executive or working memory dysfunction. In order to assess the status of syntactic knowledge in a group of patients belon...
Article
The objective was to evaluate the construct validity of the Italian version of the Frontal Behavioural Inventory (FBI) and its usefulness in the differential diagnosis of dementias. Standard criteria were used in the clinical diagnosis of dementias in 83 patients and 33 agematched healthy volunteers. The FBI scale was translated from English into I...
Article
Full-text available
The clinical relevance and extent of cognitive impairment in adult myotonic dystrophy type 1 (DM1) and 2 (DM2) is still unclear. The aim of this study was to determine whether previously reported cognitive abnormalities progress over time and if this occurs in DM2 as it does in DM1. Fifty-six patients with DM1 and 29 patients with DM2 were subjecte...
Article
Full-text available
We described a 56-years-old man with a diagnosis of “non-fluent primary progressive aphasia” (NfPPA). An accurate neuropsychological, neurological and neuroimaging evaluation was performed in order to assess clinical and behavioural features of the patient. From a neuropsychological point of view, the patient showed a typical cognitive profile of s...
Article
Action naming has been reported to be disproportionately impaired in comparison to object naming in patients with frontotemporal dementia (FTD). This finding has been attributed to the crucial role of frontal cortex in action naming. The investigation of object and action naming in the different subtypes of FTD, as well as in the related conditions...
Article
Full-text available
Non-pharmacological treatment in Alzheimer's Disease has gained great attention in recent years. The limited efficacy of drug therapy and the plasticity of human central nervous system are the two main reasons that explain this growing interest in rehabilitation. Different approaches have been developed. Here we discuss the efficacy of non-pharmaco...
Article
Patients with left-sided visuospatial neglect, typically after damage to the right parietal lobe, show a systematic bias towards larger numbers when asked to bisect a numerical interval. This has been taken as further evidence for a spatial representation of numbers, perhaps akin to a mental number line with smaller numbers represented to the left...
Article
It is usually thought that numbers are represented on a "mental number line" on which the progression of smaller to larger numbers occurs from left to right suggesting a spatial representation of numbers. Reciprocally, number processing has been shown to influence space representation [Fischer, M. (2001). Number processing induces spatial performan...
Article
Full-text available
Cholinesterase inhibitors are indicated for the symptomatic treatment of mild-to-moderate Alzheimer's Disease because they slow the progression of the disease. Its efficacy and safety have been demonstrated in placebo-controlled trials for ut to one year. By now, non-pharmachological interventions are also available; Reality Orientation Therapy (RO...
Article
The application of cognitive rehabilitation in early stage of dementia is based on theoretical evidence regarding the neuropsychology of memory impairments in Alzheimer's disease (AD). While short-term forgetting is impaired, long-term forgetting appears to be relatively spared. The memory problems in AD does not appears to be of impaired of storag...
Article
Impoverished images of faces, two-tone Mooney faces, severely impair the ability to recognize to whom the face pertains. However, previously seeing the corresponding face in a clear format helps fame-judgments to Mooney faces. In the present experiment, we sought to demonstrate that enhancement in the perceptual encoding of Mooney faces results fro...