Marco Barbieri

• Medical Doctor at University of Genoa

Obstructive sleep apnea (OSA) affects around 20% of the population, and presents potentially life-threatening consequences because of its reported association with cardiovascular events, neurocognitive impairments, and strokes. The treatment of the OSA is still a matter of debate, but the scientific community is inclined to declare that the most ef...

Since the introduction of non-resective pharyngoplasty techniques, as the expansion sphincter pharyngoplasty [1], a decrease in surgical complications and improvement of success has been observed [2].

During the last decade, with the introduction of barbed threads for pharyngoplasty surgery, several new techniques were introduced. Nowadays the new challenge is to better understand how to manage the best precision care for the surgical treatment of patients affected by obstructive sleep apnea-hypopnea syndrome (OSAHS) with pharyngeal collapse and...

Objective: To review our 5-year experience with a modified version of glossoepiglottopexy for treatment of obstructive sleep apnoea syndrome (OSA) in two hospitals. Methods: A retrospective analysis was carried out on a cohort of adult patients affected by OSA suffering from primary collapse of the epiglottis who underwent a modified glossoepigl...

Purpose: Non-resective pharyngoplasty techniques have been shown to be effective to treat oropharyngeal collapse in patients affected by obstructive sleep apnea-hypopnea syndrome (OSAHS). The aim of our study is to evaluate outcome predictors in a cohort of patients affected by OSAHS and treated with non-resective pharyngoplasty, including variati...

Purpose The aim of this study is to analyze the e cacy of a new modi ed pharyngoplasty technique with barbed sutures: barbed suspension pharyngoplasty (BSP). Methods We enrolled patients a ected by obstructive sleep apnea–hypopnea syndrome (OSAHS), having the main site of obstruction at the palatal and lateral pharyngeal walls, who refused or faile...

The treatment of obstructive sleep apnoea syndrome (OSAS) is still a matter of debate; among the different therapeutic alternatives, both surgical and conservative, treatment with continuous positive airway pressure (CPAP) is considered the “gold standard”. The recent scientific literature reports that even if CPAP represents an effective solution...

Granular cell tumour is a rare soft tissue neoplasm that can virtually affect any site of the body. Its histological origin is controversial, since several studies have shown that different cells are involved. Granular cell tumour was initially described as myoblastoma, but, at present, a neural origin is supported by most Authors, due to the immun...

Statins are serum cholesterol-lowering agents used for the prevention and treatment of atherosclerotic vascular disease. There is, however, growing evidence that statins have immunomodulatory and anti-inflammatory activities and may prove invaluable in the treatment of immunological and inflammatory disorders. On these basis we evaluated the effect...

Rinoplastide alt konka hipertrofisinin cerrahi tedavisi çok tartışmalıdır. Bu çalışmanın amacı, bu patolojinin tedavisinde, geniş hasta popülasyonunun analizi ile yüksek frekans cerrahisinin etkinliğini ve tekrarlanabilirliğini göstermektir. Burun tıkanıklığı ile gelen ve alt konka hipertrofisi olan non-allerjik 1689 hasta çalışmaya dahil edilmişti...

Background: Airway remodeling is an alteration in the size, mass, or number of tissue structural components that occurs during growth or in response to injury and/or inflammation. The primary inflammatory lesion consists of accumulation of CD4+ T-helper cell type 2 (Th2) lymphocytes and eosinophils in the airway mucosa. A first step in the control...

The aim of this study was to compare the efficacy and the safety of a short oral ribosomal immunotherapy (Immucytal) in the prevention of chronic otitis media in children. Seventy-two patients were enrolled in this study, 41 males and 31 females, aged between 6 and 14 years, with an history of recurrent otitis media. Patients were randomised to rec...

The increasing complexity of management strategies for patients with head and neck squamous cell carcinoma (HN-SCC) calls for the investigation of new objective prognostic parameters to subdivide patients according to the tumor's biological aggressiveness. We evaluated in 35 HN-SCC patients the pretreatment cell kinetics parameters and DNA ploidy a...

A case of liposarcoma, recently observed in our department, induced us to go deeper in to this subject to-highlight the histomorphological and clinical aspects, that in our patient had an interesting evolution.

The Authors examined the olfactory function of Alzheimer's patients in early stages. Olfactory identification and detection threshold have been evalued. 20 patients (10 M and 10 F) have been compared with 40 age-matched controls (20 M and 20 F). The results demonstrate dysfunctions both in identification performance and in detection threshold, that...

To determine whether pretherapy cell kinetics can predict local control for patients affected by head and neck squamous cell carcinomas (HN-SCCs) to be treated by primary radiotherapy and, moreover, guide to a choice between conventional and accelerated radiotherapy. Between 1989 and 1993, 83 patients with stage II to IV HN-SCC entered the study. M...

A 70-year-old male patient presenting with a cutaneous node of the genal region that was first diagnosed as basal cell carcinoma is described. Owing to the following observation, the authors were prompted to a diagnosis of cutaneous odontogenic sinusitis: a) examination of the lesion which emitted pus upon gentle squeezing; b) presence in the vesti...

The purpose of this phase II study was to assess the efficacy and toxicity of an accelerated radiotherapy schedule with the concomitant boost technique in the management of patients with advanced head and neck squamous cell carcinomas (HN-SCC) of various primary sites. From May 1989 to December 1992 45 patients were scheduled to receive a total dos...

Cell cycle and cell population characteristics, as obtained for head and neck cancers by flow-cytometry analysis of a single tumor sample, after in vivo bromodeoxyuridine (Burd) infusion, were proposed for their prognostic value and for their potentials for radiotherapy planning (conventional vs accelerated) and monitoring. DNA ploidy, the S phase...