Marcio Soares Serra

Federal University of Rio de Janeiro | UFRJ · Departamento de Dermatologia

Polymethyl methacrylate (PMMA) is a permanent filler used to correct furrows and deep depressions of the body and also for volume replacement. Among all permanent fillers available in the market, PMMA is the most regularly used. PMMA is demonstrated to be safe, effective, and long lasting with few adverse reactions when indicated correctly.

Permanent fillers are mainly used in the correction of furrows and deep depressions of the skin that are beyond the normal facial wrinkles that appear with aging. They can be an excellent option in facial rejuvenation, especially when there is need for facial and body volume restoration, such as in HIV lipodystrophy. Of the permanent fillers curren...

The scleroderma en coup de sabre is a variant of localized scleroderma that occurs preferentially in children. The disease progresses with a proliferative and inflammatory phase and later atrophy and residual deformity, which are treated with surgical techniques such as injectable fillers, transplanted or autologous fat grafting and resection of th...

Progression of lipodystrophy syndrome is a big challenge in HIV treatment. Nowadays, fat loss at the lower part of buttocks has become another problem as patients have started to complain that it is painful to be seated for a long time and/or on hard surfaces. We developed a method for buttock lipoatrophy treatment with PMMA-microspheres, as silico...

Melasma is an acquired, irregularly patterned, light to dark-brown hypermelanosis, with symmetric distribution mostly over the face. The aim of this study was to evaluate clinical characteristics and factors related to melasma in Brazilian patients. This was a cross-sectional, multicenter study performed in Brazil. Investigators examined and questi...

Background Treatment of facial lipoatrophy of HIV/AIDS patients is mandatory by law in Brazil due to its negative impact on their quality of life. The index for facial lipoatrophy (ILA) is used as one of the inclusion criteria for patient treatment. Objectives To define a correct diagnosis and staging of facial lipoatrophy, by employing the ILA. Pa...

Metástases cutâneas de câncer visceral são relativamente raras, com uma incidência de 0,7-10%. Os sítios primários mais frequentes são os tumores de mama, pulmão e cólon. Geralmente ocorrem após o câncer primário ser diagnosticado e significam mau prognóstico. Podem surgir como primeira manifestação em 20% das neoplasias em geral. As manifestações...

Cutaneous metastases of visceral cancers are relatively rare, with an incidence of 0.7 to 10%. The most frequent primary sites are breast, lung and colon tumors. They generally occur after the primary cancer is diagnosed and signify a poor prognosis. They may occur as the first manifestation in 20% of cancers in general. The most common manifestati...

A infecção pelo HIV não altera a história natural da hanseníase. Observa-se maior incidência de estados reacionais nos pacientes co-infectados, além de casos mais graves de neurite. Paciente soropositiva com hanseníase dimorfa tuberculóide manifestou reação reversa exuberante. Lesões cutâneas atípicas e raras surgiram após a introdução da terapia a...

HIV infection does not modify the natural course of leprosy. However, HIV co-infection seems to be associated with an increased rate of reactional states and more severe cases of neuritis. The authors describe a case of borderline tuberculoid leprosy in a HIV-positive patient who developed a marked reversal reaction. Atypical and rare skin manifest...

Despite the temporary side effects that cause a degree of discomfort, phosphatidylcholine injections can be used successfully in the treatment of localized and small fatty areas of the face, as it requires a few injections and less than one vial. Injection of phosphatidylcholine seems to be a better, safer, and more cost-effective treatment than li...

Phosphatidylcholine was initially used in emergencies and in the treatment of atheroma plaques in cardiac diseases. Recently, it has also been used in the treatment of localized fat deposits. We report on the authors' clinical experience of the use of 250 mg/ml phosphatidylcholine injections in the treatment of subcutaneous fat deposits, showing th...