Marcelo Pires Amaral

Marcelo Pires Amaral
Universidade Federal de São Paulo | UNIFESP · Departamento de Microbiologia, Imunologia e Parasitologia

Master of Science
PhD candidate at Federal University of São Paulo (UNIFESP), Brazil

About

7
Publications
317
Reads
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30
Citations
Introduction
PhD student at Federal University of São Paulo (UNIFESP), Brazil. The focus of my project is to investigate the role of inflammasome proteins in response to protozoan parasites infections.
Education
July 2018 - July 2022
Universidade Federal de São Paulo
Field of study
  • Microbiology, Immunology and Parasitology
March 2016 - March 2018
Universidade Federal de São Paulo
Field of study
  • Microbiology, Immunology and Parasitology
January 2011 - December 2015
Universidade Federal de São Paulo
Field of study
  • Biological Sciences

Publications

Publications (7)
Article
Full-text available
Chikungunya virus (CHIKV) is an arbovirus transmitted to humans mainly by the bite of infected Aedes aegypti and Aedes albopictus mosquitoes. CHIKV illness is characterized by fever and long-lasting arthritic symptoms, and in some cases it is a deadly disease. The CHIKV envelope E2 (E2CHIKV) glycoprotein is crucial for virus attachment to the cell....
Article
Full-text available
Although the influence of sleep quality on the immune system is well documented, the mechanisms behind its impact on natural host immunity remain unclear. Meanwhile, it has been suggested that neuroimmune interactions play an important role in this phenomenon. To evaluate the impact of stress-induced sleep disturbance on host immunity, we used a mu...
Article
Caspase-8 is a master regulator of cell death pathways, although its regulation during inflammation remains elusive. Using elegant mouse genetic approaches, Schwarzer et al. and Tummers et al. revealed the importance of FADD in regulating caspase-8-mediated inflammatory responses and gut homeostasis.
Article
The recent outbreaks of Zika virus (ZIKV) infection and the potential association with Guillain-Barré syndrome in adults and with congenital abnormalities have highlighted the urgency for an effective vaccine. The ZIKV Envelope glycoprotein (EZIKV) is the most abundant protein on the virus surface, and has been evaluated together with the pre-membr...
Article
Astrocytes and microglia are the most abundant glial cells. They are responsible for physiological support and homeostasis maintenance in the central nervous system (CNS). The increasing evidences of their involvement in the control of infectious diseases justify the emerging interest in the improvement of methodologies to isolate primary astrocyte...
Article
Although the influence of sleep quality on the immune system is well documented, the mechanisms behind its impact on natural host immunity remain unclear. Meanwhile, it has been suggested that neuroimmune interactions play an important role in this phenomenon. To evaluate the impact of stress-induced sleep disturbance on host immunity, we used a mu...

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Projects

Project (1)
Project
The goal of my project is to investigate the role of inflammasome proteins in response to parasitic infections.