Marcelo Papoti

São Paulo State University | Unesp · Department of Physical Education

This study aimed to investigate the influence of photobiomodulation therapy (PBMT) in hypoxia (HYP) and normoxia (NOR) on time to exhaustion and the energetic contribution of treadmill running in amateur athletes. Eleven male participants, aged between 18 and 29 years, were submitted to an incremental test to determine the iV̇O2max, and subsequentl...

The aim of this study was to investigate the effect of 8 weeks of hypoxic exposition and physical training on healthy mice femur outcomes analyzed through conventional statistic and complex networks. The mice were divided into four groups, subjected to physical training (T; 40 min per day at 80% of critical velocity intensity) or not (N), exposed t...

Purpose The gold standard measure of anaerobic contribution is accumulated oxygen deficit (AOD). The purpose of this study was to investigate the validity of an alternate measure, AOD_alt. AOD_alt is the sum of the phosphocreatine and glycolytic contributions, which are estimated from post-exercise oxygen uptake and blood lactate concentration, res...

The present study aimed to verify the effect of acute nitrate supplementation on oxidative, phosphocreatine, and glycolytic energy contribution (COXI, CPCr, and CLAC , respectively) during a high-intensity intermittent exercise (HIIE). Fifteen physically active subjects were submitted to incremental running test on a treadmill and two random HIIE (...

This investigation aimed to assess if alternative method to estimate the maximal accumulated oxygen deficit (MAODalt) can detect changes in energy system contribution in different substrate availabilities. Following a graded exercise test to determine maximal oxygen uptake intensity (iVO2max), 26 recreational runners performed a time to exhaustion...

International Journal of Exercise Science 17(2): 648-659, 2024. This study aimed to investigate the effects of chronic β-alanine (βA) plus acute sodium bicarbonate (SB) co-supplementation on neuromuscular fatigue during high-intensity intermittent efforts in swimming. Eleven regional and national competitive-level young swimmers performed a neuromu...

International Journal of Exercise Science 17(6): 670-681, 2024. Smartpaddle ® is a novel wearable device based on inertial measurement units (IMU) for in-field arm-stroke kinetics and kinematics analysis in swimming. However, the lack of data regarding its agreement and reliability, coupled with restricted access to raw data, emphasizes the need to...

Norberto, Matheus S., João Victor G. Torini, Matheus S. Firmino, and Marcelo Papoti. Validation of air storage system for hypoxia exposure during exercise. High Alt Med Biol. 00:000-000, 2024.-Considering the importance of optimizing normobaric hypoxia exposure (i.e., higher delivery capacity), the current study aims to validate a hypoxic air stora...

Although adding hypoxia to high-intensity training may offer some benefits, a significant problem of this training model is the diminished quality of the training session when performing efforts in hypoxia. The purpose of the present study was to investigate the effects of training and tapering combined with inter-effort recovery hypoxia (IEH) on a...

Inspiratory muscles pre-activation (IMPA) has been studied to improve subsequent performance in swimming. However, the effects of IMPA on various parameters in swimmers are still unknown. Therefore, this study aimed to investigate the effects of IMPA on the mechanical parameters, physiological responses, and their possible correlations with swimmin...

This study aimed to investigate the effects of a 4-week live high train low (LHTL; FiO2 ~ 13.5%), intervention, followed by a tapering phase, on muscle glycogen concentration. Fourteen physically active males (28 ± 6 years, 81.6 ± 15.4 kg, 179 ± 5.2 cm) were divided into a control group (CON; n = 5), and the group that performed the LHTL, which was...

Introduction Traditional intermittent hypoxia training improves sport performance after short periods of exposure, but acute exposure to intermittent hypoxia leads to decreased training intensity and technical quality. The solution to overcome these negative effects may be to perform efforts in normoxia and the intervals between efforts in hypoxia,...

The total anaerobic contribution (AC[La-]+PCr) is a valid and reliable methodology. However, the active muscle mass plays an important role in the AC[La-]+PCr determination, which might influence its reliability. Thus, this study aimed to investigate the effects of two exhaustive intensities on the reliability of the AC[La-]+PCr during a one-legged...

To test the reproducibility of the 3-min all-out effort applied using shuttle running and compare its values to aerobic parameters. On the first day, fourteen futsal players underwent an exhaustive test to determine the maximal incremental speed (MIS) and anaerobic threshold (AnT). On the second day, the participants performed the 3-min all-out eff...

High-intensity interval training (HIIT) is a popular method for optimising sports performance and, more recently, improving health-related parameters. The inclusion of hypoxia during HIIT can promote additional gains compared with normoxia. However, reductions in the effort intensities compared with the same training performed in normoxia have been...

Introduction Traditional intermittent hypoxia training improves sport performance after short periods of exposure, but acute exposure to intermittent hypoxia leads to decreased training intensity and technical quality. The solution to overcome these negative effects may be to perform efforts in normoxia and the intervals between efforts in hypoxia,...

INTRODUÇÃO: O goalball é um esporte paralímpico desenvolvido especialmente para pessoas com deficiência visual. Embora a dinâmica do jogo ocorra por ações intermitentes subsidiadas pelo metabolismo anaeróbio alático, a exigência da modalidade é predominantemente aeróbia. Dessa forma, considerando a importância desse parâmetro para a manutenção e re...

To evaluate the effects of photobiomodulation on the physical performance of healthy women, considering the menstrual cycle. 27 physically active healthy women (age 25.68 ± 3.99 years; mass 63.76 ± 12.77 kg; height 1.65 ± 0.59 cm) during the initial follicular phase (FF1 and FF2) of the menstrual cycle underwent performance evaluations, through a s...

Literature diverges about the performance improvement after dry-land training. Thus, the objective of the present study was to compare the effect of two models of dry-land training. Twenty-nine swimmers were divided into three groups, combined strength and power training (PTG), only strength training (STG), and a control group (CG). Measurements we...

BACKGROUNDː Deep Water Running (DWR) is an exercise model often used for health promotion purposes. This study standardized an aerobic capacity evaluation protocol specific for attached DWR in young healthy adults and monitored a DWR session with normobaric hypoxia exposure addition. METHODSː In Study 1, nine young healthy adults, seven male and tw...

There is a scarcity of data regarding the acclimation to high altitude (hypoxic environment) accompanied by training at low altitude (normoxic conditions), the so-called "living high-training low" (LHTL) model in rodents. We aimed to investigate the effects of aerobic training on C57BL/6J mice living in normoxic (NOR) or hypoxic (HPY) environments...

Objective To analyze the physical performance, self-perception menstrual symptoms, of physically active eumenorrheic women with endogenous ovarian cycle in two phases of the menstrual cycle. Methods Twenty-six women participated in the study (age 25.8 ± 3.9 years; height 1.64 ± 0.58 m; mass 64 ± 12.32 kg; menarche 11.69 ± 1.28 years). Assessments...

During the COVID-19 pandemic, several late-onset impairments have been observed, affecting the health and functionality of those involved. On the other hand, lower SARS-CoV-2 infection rates and severity of symptoms were observed in high-altitude cities. In this sense, the AEROBICOVID project was developed with the hypothesis that exercise would be...

Hypoxic exposure is safely associated with exercise for many pathological conditions, providing additional effects on health outcomes. COVID-19 is a new disease, so the physiological repercussions caused by exercise in affected patients and the safety of exposure to hypoxia in these conditions are still unknown. Due to the effects of the disease on...

This study investigated the physiological and molecular responses of Wistar Hannover rats, submitted to three 5-week chronic training models, with similar training loads. Twenty-four Wistar Hanover rats were randomly divided into four groups: control (n = 6), low-intensity training (Z1; n = 6), moderate-intensity training (Z2; n = 6) and high-inten...

Background Recent studies have indicated that people who live at altitude have a lower incidence of coronavirus disease (COVID-19) and lesser severity in infection cases. Hypothesis Hypoxia exposure could lead to health benefits, and it could be used in the recovery process as an additional stimulus to physical training to improve cardiorespirator...

The present study aimed to compare the MAODALT in situations of hypoxia and normoxia to confirm the method validity. Seventeen healthy and physically active men participated in this study, aged 25.2 ± 3.2 years. All participants underwent four days of evaluation. The first day was performed a body composition test, an incremental test to exhaustion...

Aims It is known that the synthesis of monocarboxylate transporters (MCTs) can be stimulated by aerobic training, but few about this effect associated or not with non-voluntary daily activities. We examined the effect of eight weeks of aerobic training in MCTs on the skeletal muscle and hypothalamus of less or more physically active mice, which can...

Evaluation of anaerobic contribution is important under swimming settings (training and modification through ages), therefore, it is expected to change during maturation. The accumulated oxygen deficit (AOD) method can be used to determine the contribution of nonoxidative energy during swimming; however, it requires several days of evaluation. An a...

International Journal of Exercise Science 15(7): 599-615, 2022. The anaerobic metabolism determination is complex and the applied methodologies present limitations. Thus, the purpose of this study was to investigate the effects of different calculations (MAOD vs. AOD) on the anaerobic contribution using the dynamic knee extension. Twenty-four male...

This study aimed to investigate the effects of 6-week specific preparatory period and 2-week taper period on neuromuscular fatigue profile in 100-m front crawl swimming performance. Seventeen competitive-level young-adult swimmers performed a 100-m swimming performance at baseline and after 6-week specific preparatory followed by 2-week taper perio...

Galectins are multifunctional glycan-binding proteins present in various tissues that participate in multiple physiological and pathological processes and are considered as not only biomarkers of human diseases but also molecular targets for treating cancer and inflammatory illnesses in many organs. In the glycobiology field, it is crucial to deter...

BACKGROUND: Environment with low oxygen availability can have detrimental effects on cognitive abilities. Nevertheless, exercise can have beneficial effects on cognitive abilities, and these effects may vary with the environment. Therefore, it is important for the performance of individuals to understand the uncertainties about the conditions that...

Background - Considering photobiomodulation for muscle performance, the data in the current literature are conflicting and restricted regarding some parameterizations, with divergences in wavelength, power, and energy density applied. Therefore, analyzing different doses for the responses associated with strength capabilities and fatigue resistance...

Problem Statement: The motivation to increase performance or monitoring capacity shapes the findings and advances in the field. Objective: The objective was to evaluate the correlation between different training impulses and their relationship with isolated variables such as maximum heart rate (HRmax), lactate ([La-] b), glucose (GLU), rating of pe...

This study investigated the 30-days altitude training (2500 m, LHTH-live and training high) on hematological responses and aerobic–anaerobic performances parameters of high-level Paralympic athletes. Aerobic capacity was assessed by 3000 m run, and anaerobic variables (velocity, force and mechanical power) by a maximal 30-s semi-tethered running te...

Background & Aims Metformin demonstrated potential to improve metabolic efficiency in short-intense and prolonged-continuous efforts. The present study investigates the acute effects of metformin intake on performance, rating of perceived exertion (RPE), blood lactate, blood glucose and neuromuscular parameters related to swimming high-intensity in...

Background Recent studies point to a lower number and reduced severity of cases in higher altitude cities with decreased oxygen concentration. Specific literature has shown several benefits of physical training, so, in this sense, physical training with hypoxic stimulus appears as an alternative that supports the conventional treatments of the COVI...

The primary aim of this study was to compare the measured oxygen consumption (Measured-VO2) in a simulated futsal game (S-Game) with the estimated oxygen consumption (Estimated-VO2) through a regression equation between heart rate (HR) and oxygen consumption (VO2) (HR-VO2) in treadmill running, and a secondary aim was to calculate the total energy...

Background: Recent studies point to a lower number and a reduction in the severity of cases in higher altitude cities, with decreased oxygen concentration. Specific literature has shown several benefits of physical training, so, in this sense, physical training with hypoxic stimulus appears as an alternative that supports the conventional treatment...

[This corrects the article DOI: 10.3389/fphys.2020.580711.].

Background: This study investigated the possible influence of the gender on the responses of swimmers during a taper period (TP). Methods: Ten males (19 ± 3 years and 73.5 ± 7.8 kg) and ten females (17 ± 2 years and 54.7 ± 7.2 kg) swimmers were submitted to a 12-week training, followed by three weeks of the TP. Before and after the TP we evaluat...

BACKGROUND: This study investigated the relationship between the lactate minimum (LACmin) and the 10- (T10) and 30-min (T30) continuous tests in swimmers. METHODS: Twelve swimmers (78.1 ± 3.1% of world record) performed the LACmin (hyperlactatemia: 2 x 50 m all-out 8-min apart, incremental part: n x 300 m 30-s apart), T30 and T10 using the front-c...

Physiological responses in futsal have not been studied together with temporal information about the players’ stay on the court. The aim of this study was to compare heart rate (HR) and blood lactate concentration ([La⁻]) responses between 1-H and 2-H considering the time of permanency of the players on the court at each substitution in a futsal ma...

Background: Beta-alanine has become a dietary supplement widely used by athletes due to its ergogenic effect. However, there is still no consensus on the performance benefit of beta-alanine on exercise lasting longer than ten minutes. The present study aimed to evaluate the effect of beta-alanine supplementation on running performance and the expr...

Background: Investigations of β-alanine supplementation shows effects on metabolic (aerobic and anaerobic) participation and performance on swimming by a possible blood acidosis buffering. Considering this background, the objective of the present study was to analyze the effects of β-alanine supplementation on metabolic contribution and performanc...

No presente estudo, objetivou-se testar se a melhora da capacidade aeróbia, observada após oito semanas de treinamento, é transferida para a capacidade de sprints repetitivos (CSR). Dez corredores (18 ± 1 ano; estatura de 170,1 ± 8,0 cm; massa corporal de 66,4 ± 6,6 kg) participaram do estudo. A capacidade aeróbia foi considerada como a intensidade...

This study aimed to propose a conditioning activity (CA) model to stimulate improvement on neuromuscular responses, mechanical parameters and for the 50-m freestyle swimming. Thirteen male swimmers (19 ± 3 years and performances of 77% in relation to World Championship records) performed four CA protocols followed by a maximum performance in the 50...

Background: Backward extrapolation technique (BE) is used to estimate V̇ O2 from post-exercise measuring, eliminating oronasal mask (OM) during the efforts. Despite its advantage, literature presents discrepancy in applied methods. Thus, the aim of this study is to compare different mathematical criteria to estimate values of V̇ O2 during a supram...

An amendment to this paper has been published and can be accessed via the original article.

Purpose Açai pulp is a source of phytochemicals and has been associated with antioxidant, anti-inflammatory, and antigenotoxic effects. This study aimed to assess the effects of açai pulp consumption on oxidative, inflammatory, and aerobic capacity markers of cyclist athletes. Research methods and procedures A crossover, randomized, placebo-contro...

Analyze the effects of sequential application of photobiomodulation therapy (PBMT) at different wavelengths on the performance of cycling athletes. Cyclists (48 male, mean age 33.77 years) underwent a performance evaluation through an incremental test, VO2max, blood lactate analysis, perception of effort, infrared thermography, and isokinetic evalu...

No presente estudo, objetivou-se testar se a melhora da capacidade aeróbia, observada após oito semanas de treinamento, é transferida para a capacidade de sprints repetitivos (CSR). Dez corredores (18 ± 1 ano; estatura de 170,1 ± 8,0 cm; massa corporal de 66,4 ± 6,6 kg) participaram do estudo. A capacidade aeróbia foi considerada como a intensidade...

Introdução: A utilização de métodos específicos de mensuração é de fundamental importância para a identificação da capacidade aeróbia e prescrição da intensidade de exercício. Normalmente esta definição é feita pela determinação do limiar anaeróbio (Lan) que corresponde à máxima fase estável entre produção e remoção de lactato sanguíneo (MFEL). Den...

Neuromuscular fatigue evaluation is widely performed on different muscles through the conventional protocol using maximum voluntary contraction (MVC) with electrical stimuli in the analyzed muscle. In an attempt to use this protocol on elbow extensor musculature, previous studies and pilot studies showed co-contraction effects from antagonist muscu...

Background and Study Aim: Judo has been characterized as a high-intensity intermittent combat sport. The study’s purpose is answer the question whether Special Judo Fitness Test (SJFT) variables are capable of discriminate young judo athlete’s performance at different ages, and comparing the test with metabolic indicators and energy contribution. M...

This study aimed to compare the Maximum Accumulated Oxygen Deficit determined by the conventional method (MAODC) with that determined by the backward extrapolation technique (MAODEXTR) in runners. Fourteen runners underwent a maximal incremental test for determination of iVO2MAX, ten submaximal efforts (50-95% of iVO2MAX for 7 min). During the subm...

Background: In the dynamic knee extension (DKE), a metal bar is positioned parallel to bicycle frame, replacing the pedal of a cycle ergometer, which allow consecutives extensions instead of pedaling movement. Considering the fixed ratchet of cycle ergometer, the knee joint returns to its initial position passively, isolating the quadriceps group d...

No presente estudo, objetivou-se testar se a melhora da capacidade aeróbia, observada após oito semanas de treinamento, é transferida para a capacidade de sprints repetitivos (CSR). Dez corredores (18 ± 1 ano; estatura de 170,1 ± 8,0 cm; massa corporal de 66,4 ± 6,6 kg) participaram do estudo. A capacidade aeróbia foi considerada como a intensidade...

No presente estudo, objetivou-se testar se a melhora da capacidade aeróbia, observada após oito semanas de treinamento, é transferida para a capacidade de sprints repetitivos (CSR). Dez corredores (18 ± 1 ano; estatura de 170,1 ± 8,0 cm; massa corporal de 66,4 ± 6,6 kg) participaram do estudo. A capacidade aeróbia foi considerada como a intensidade...

BACKGROUND: Metformin has shown potential to improve metabolic efficiency in short-intense efforts, prolonged-continuous efforts and recovery after supramaximal effort (i.e., phosphocreatine resynthesis). Metformin administration may be beneficial for high-intensity interval training session. The aim of the present study was to investigate the acut...

INTRODUÇÃO: A fotobiomodulação por LED (TLED) é uma modalidade crescente no desempenho físico. OBJETIVOS: Analisar os efeitos agudos da fotobiomodulação nas capacidades de resistência à fadiga e recuperação após exercícios extenuantes de atletas universitários, quando aplicada pré (TLED-PRÉ) ou 15 minutos antes do exercício (TLED-15). METODOLOGIA:...

Background: Exercise training may improve energy expenditure, thermogenesis, and oxidative capacities. Therefore, we hypothesized that physical training enhances white adipose tissue mitochondrial oxidative capacity from obese women. Objective: To evaluate mitochondrial respiratory capacity, mitochondrial content and UCP1 gene expression in whit...

Background Heart rate variability (HRV) has proven to be a powerful non-invasive tool to investigate cardiac autonomic control and, seems to be influenced by nutritional status and exercise practice. However, the acute effects of fed or fasting states on HRV and blood pressure (BP) during low-to-moderate intensity aerobic exercise are currently unk...

Purpose This study aimed to verify the influence of chronological age on maximal accumulated oxygen deficit (MAOD) and the correlations with maximal oxygen uptake (VO2PEAK) and intensity (vVO2PEAK). Methods Thirty-one male athletes underwent an incremental exercise test involving 10 submaximal efforts (50–95% of velocity corresponding to VO2PEAK [...

The purpose of the present study was to investigate the ergogenic effects of 4 weeks of β-alanine supplementation on peak oxygen uptake (V˙O2peak) and force associated with V˙O2peak (FV˙O2peak) during a tethered swimming graded exercise test, and a three-minute all-out effort (3minALL-OUT) in water polo players. Twenty-two male national competitive...

DATA SET.xlsx. Individual data set for the tethered swimming graded exercise test and three-minute all-out effort. (XLSX)

The aim of the present study was to investigate the differences in energy system contributions and temporal variables between offensive and all-round playing styles. Fifteen male table tennis players (Offensive players: N = 7; All-round players: N = 8) participated in the study. Matches were monitored by a portable gas analyzer and the blood lactat...