Marc Muehlmann

Marc Muehlmann
Technische Universität München | TUM · Abteilung für Interventionelle Radiologie

Doctor of Medicine
Board certified Radiologist

About

33
Publications
8,480
Reads
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965
Citations
Citations since 2017
16 Research Items
840 Citations
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2017201820192020202120222023050100150
2017201820192020202120222023050100150
2017201820192020202120222023050100150
Additional affiliations
September 2022 - present
Technische Universität München
Position
  • Attending
February 2014 - March 2015
Brigham and Women's Hospital
Position
  • Research Associate
January 2012 - September 2022
Ludwig-Maximilians-University of Munich
Position
  • Physician

Publications

Publications (33)
Article
Full-text available
Background Deep learning is a promising technique to improve radiological age assessment. However, expensive manual annotation by experts poses a bottleneck for creating large datasets to appropriately train deep neural networks. We propose an object detection approach to automatically annotate the medial clavicular epiphyseal cartilages in compute...
Article
Neurological soft signs (NSS) are minor deviations in motor performance. During childhood and adolescence, NSS are examined for functional motor phenotyping to describe development, to screen for comorbidities, and to identify developmental vulnerabilities. Here, we investigate underlying brain structure alterations in association with NSS in physi...
Article
Quantification methods based on the acquisition of diffusion magnetic resonance imaging (dMRI) with multiple diffusion weightings (e.g., multi-shell) are becoming increasingly applied to study the in-vivo brain. Compared to single-shell data for diffusion tensor imaging (DTI), multi-shell data allows to apply more complex models such as diffusion k...
Chapter
Full-text available
Full text link: https://user-swndwmf.cld.bz/28-Primary-and-secondary-liver-malignancies
Article
Background: Repetitive head impacts (RHI) from contact sports have been associated with cognitive and neuropsychiatric disorders. However, not all individuals exposed to RHI develop such disorders. This may be explained by the reserve hypothesis. It remains unclear if the reserve hypothesis accounts for the heterogenous symptom presentation in RHI...
Article
Background To evaluate technical and clinical results of stent-graft (SG) placement in patients with bleeding from the hepatic artery (HA). Methods All patients intended and treated with SG deployment for bleeding from the HA at single center from January 2012 to May 2020 were retrospectively identified, and procedural details, risk factors for re...
Chapter
For various tumor entities and liver metastases thereof, it has been shown that control of the hepatic metastases has a dominant influence on survival. Various local ablative and locoregional therapeutic techniques have been shown to be safe and effective in treating liver metastases of various cancer entities. Catheter-based radiotherapy/brachythe...
Article
Objectives To evaluate the efficacy and safety of urgent percutaneous embolization for the treatment of acute renal hemorrhage. Materials and Methods All patients undergoing endovascular embolization at our hospital for bleeding from renal artery branches between January 2010 and June 2020 were retrospectively evaluated. Periprocedural characteris...
Article
Hepatic tumors include hepatocellular cancer (HCC) and cholangiocarcinoma (CC), a small subgroup of tumors (approx. 1%) are classified as combined hepatocellularcholangiocellular carcinomas. Different stage-dependent therapeutic approaches comprise resection, local ablative techniques, locoregional therapies, systemic treatment, liver transplantati...
Article
Clinical problem: The indication for resuscitation room care is an acute (potentially) life-threatening patient condition. Typical causes for this are polytrauma, acute neurological symptoms, acute chest and abdominal pain or the cause remains unclear at first. The care is always provided in a suitably composed interdisciplinary team. This require...
Article
Full-text available
Background Factors of increased prevalence among individuals with Black racial identity (e.g., cardiovascular disease, CVD) may influence the association between exposure to repetitive head impacts (RHI) from American football and later-life neurological outcomes. Here, we tested the interaction between racial identity and RHI on neurobehavioral ou...
Article
Full-text available
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts. CTE has been linked to disruptions in cognition, mood, and behavior. Unfortunately, the diagnosis of CTE can only be made post-mortem. Neuropathological evidence suggests limbic structures may provide an opportunity to characte...
Article
Background In patients with multiple trauma, abdominal involvement is a particularly relevant injury pattern. Depending on the intensity and manner of injury, heterogeneous but often typical organ manifestations result. Knowledge of these injury patterns is essential for targeted diagnostics and treatment. Objective This review provides a presenta...
Article
Full-text available
The aim of this study was to evaluate longitudinal changes in the diffusion characteristics of brain white matter (WM) in collegiate athletes at three time points: prior to the start of the football season (T1), after one season of football (T2), followed by six months of no-contact rest (T3). Fifteen male collegiate football players and 5 male non...
Article
Full-text available
Primary Objective: There is a need to understand pathologic processes of the brain following mild traumatic brain injury (mTBI). Previous studies report axonal injury and oedema in the first week after injury in a rodent model. This study aims to investigate the processes occurring 1 week after injury at the time of regeneration and degeneration us...
Article
Full-text available
Background: Worldwide more than 22 million children and adolescents are exposed to repetitive head impacts (RHI) in soccer. Evidence indicates cumulative effects on brain structure, but it is not known whether exposure to RHI affects cognitive improvement in adolescents. To determine whether exposure to RHI while heading the ball in soccer affects...
Article
Importance: Vitamin B12, folate, and sulfur amino acids may be modifiable risk factors for structural brain changes that precede clinical dementia. Objective: To investigate the association of circulating levels of vitamin B12, red blood cell folate, and sulfur amino acids with the rate of total brain volume loss and the change in white matter h...
Article
Full-text available
Post-mortem studies reveal a high rate of cavum septi pellucidi (CSP) in chronic traumatic encephalopathy (CTE). It remains, however, to be determined whether or not the presence of CSP may be a potential in vivo imaging marker in populations at high risk to develop CTE. The aim of this study was to evaluate CSP in former professional American foot...
Article
Soccer is the most popular sport in the world. Soccer players are at high risk for repetitive subconcussive head impact when heading the ball. Whether this leads to long-term alterations of the brain's structure associated with cognitive decline remains unknown. The aim of this study was to evaluate cortical thickness in former professional soccer...
Article
Dyslexia is characterized by a deficit in language processing which mainly affects word decoding and spelling skills. In addition, children with dyslexia also show problems in mathematics. However, for the latter, the underlying structural correlates have not been investigated. Sixteen children with dyslexia (mean age 9.8 years [0.39]) and 24 typic...
Article
Full-text available
Youth football players may incur hundreds of repetitive head impacts (RHI) in one season. Our recent research suggests that exposure to RHI during a critical neurodevelopmental period prior to age 12 may lead to greater later-life mood, behavioral, and cognitive impairments. Here we examine the relationship between age of first exposure (AFE) to RH...
Article
Full-text available
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease confirmed at postmortem. Those at highest risk are professional athletes who participate in contact sports and military personnel who are exposed to repetitive blast events. All neuropathologically confirmed CTE cases, to date, have had a history of repetitive head impacts. This...
Article
Full-text available
Soccer is played by more than 250 million people worldwide. Repeatedly heading the ball may place soccer players at high risk for repetitive subconcussive head impacts (RSHI). This study evaluates the long-term effects of RSHI on neurochemistry in athletes without a history of clinically diagnosed concussion, but with a high exposure to RSHI. Eleve...
Article
Background Early unilateral brain lesions can lead to different types of corticospinal (re-) organization of motor networks. In one group of patients, the contralesional hemisphere exerts motor control not only over the contralateral non-paretic hand but also over the (ipsilateral) paretic hand, as theprimary motor cortex is (re-)organized in the c...
Chapter
Diffusion tensor imaging (DTI) is an advanced magnetic resonance imaging (MRI) technique that provides detailed information about tissue microstructure such as fiber orientation, axonal density, and degree of myelination. DTI is based on the measurement of the diffusion of water molecules. It was developed in the early 1990s and since then has been...
Article
Full-text available
Object: The aim of this study was to examine the brain's white matter microstructure by using MR diffusion tensor imaging (DTI) in ice hockey players with a history of clinically symptomatic concussion compared with players without a history of concussion. Methods: Sixteen players with a history of concussion (concussed group; mean age 21.7 ± 1....
Article
Objectives: The aim of this study was to investigate the relationship between the pressure setting of the ventriculoperitoneal (VP) shunt valve and a magnetic resonance (MR)-based estimate of intracranial pressure (ICP) in children with shunt-treated hydrocephalus without clinical signs of shunt malfunction. Materials and methods: Institutional...
Conference Paper
PURPOSE 1) To investigate the correlation between the pressure setting of the ventriculo-peritoneal shunt (VP-shunt) valve and an MR-based estimate of the intracranial pressure (MRICP) in patients with hydrocephalus. 2) To analyze the effect of the ventricle volume on the MRICP. METHOD AND MATERIALS Sixteen consecutive patients (median age 9.5 yea...
Article
Full-text available
Clinical/methodical issue: The intracranial pressure (ICP) is a crucially important parameter for diagnostic and therapeutic decision-making in patients with hydrocephalus. Standard radiological methods: So far there is no standard method to non-invasively assess the ICP. Various approaches to obtain the ICP semi-invasively or non-invasively are...

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