Marc Henry

Marc Henry
University of Strasbourg | UNISTRA · Laboratoire de Synthèse et Fonctions des Architectures Moléculaires

PhD

About

186
Publications
28,724
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
9,168
Citations
Introduction
Marc Henry currently works at the Laboratoire de Synthèse et Fonctions des Architectures Moléculaires, University of Strasbourg. Marc does research in Chemical Thermodynamics, Inorganic Chemistry, Materials Chemistry, homeopathy and consciousness.
Additional affiliations
September 2020 - present
University of Strasbourg
Position
  • Professor Emeritus
October 1993 - September 2020
University of Strasbourg
Position
  • Principal Investigator
October 1981 - October 1993
Sorbonne Université
Position
  • Senior Researcher

Publications

Publications (186)
Article
M. Henry (2020) Conscious- ness, Information, Electromagnetism and Water. Substantia 4(1): 23-36.
Article
Full-text available
Abstract: From a thought experiment on the observation of a human intellect by itself, we will attempt to demonstrate that, unlike what many neuroscientists postulate, assemblies of neurons do not generate consciousness: Consciousness pre-exists any material system. Keywords: Consciousness, meaning, information, activity, neurons.
Article
A Ti( iv )-complex with thermotropic liquid crystal properties is reported.
Article
Full-text available
Specialization characterizes pharmacology, with the consequence of classifying the various treatments into unrelated categories. Treating a specific disease usually requires the design of a specific drug. The second law of thermodynamics is the driving force both for chemical reactions and for life. It applies to diseases and treatment. In most com...
Article
The formation of a tetranuclear self‐assembled species constructed around a TiO 4 N 2 motif is reported. This aggregate is generated from Ti(O i Pr) 4 , 2,2’‐bipyrimidine (bpym) and a bisbiphenol strand (L 2 H 4 ) where two 2,2’‐biphenol units are connected with a biphenyl spacer. The solid‐state structure of the [Ti 4 (L 2 ) 4 (bpym) 4 ] architect...
Article
Full-text available
Singlet dioxygen 1O2 is one excited state among the three other possible spectroscopic states of molecular oxygen. Here, we first describe the use of published spectroscopic data and thermodynamic modeling based on irreversible entropy production. Such concepts are further applied to the synthesis of singlet dioxygen and its reactions with crucial...
Article
The synthesis and characterisation of novel chelate nitrogen ligands with phasmidic tails (pyridine-triazole ligand 1b; 2,2'-bipyrimidine ligands 2b and 3b) as well as their titanium(IV) coordination complexes are reported. The analogous ligands 1a, 2a and 3a with methoxy substituents instead of the tails were also synthesized, together with titani...
Article
Full-text available
A hyper-specialization characterizes modern medicine with the consequence of classifying the various diseases of the body into unrelated categories. Such a broad diversification of medicine goes in the opposite direction of physics, which eagerly looks for unification. We argue that unification should also apply to medicine. In accordance with the...
Article
Full-text available
In nature, every physical process involving matter is ruled by the second law of thermodynamics (the total entropy of an isolated system can never decrease over time, and is constant if and only if all processes are reversible). The living cell being a material system should comply by releasing entropy either into the body or into the outside envir...
Article
Dipyrrolyldiketone ligands (dpkH) are used with Ti(OiPr)4 to afford monomeric titanium(IV) complexes displaying the general formula C2-[Ti(dpk)2(OiPr)2]. The dpkH ligands employed consist of two dipyrrolyldiketone compounds (2H and 3H) and three diphenyl-substituted analogues (4H-6H). The behavior of these octahedral [Ti(dpk)2(OiPr)2] species in so...
Article
A multicomponent self‐assembly reaction involving a bis‐biphenolato ligand (LH4), a 2,2'‐bipyrimidine chelate substituted by two (anthryl)vinyl moieties (bAnt) and Ti(OiPr)4 was investigated. An assembly {[Ti3(L)3(bAnt)3]}, composed of three homochiral TiO4N2 nodes, was characterized as being the thermodynamically‐end product. The crystal structure...
Article
The synthesis of monomeric octahedral complexes constructed around a TiO4N2 core bearing neocuproine derivatives is detailed. These architectures follow the [Ti(1)2(N-N)] general formulas, where 1 is the 6,6'-diphenyl-2,2'-biphenolato ligand and N-N is a 1,10-phenanthroline derivative. Single-crystal analysis revealed that the neocuproine-based lig...
Article
Background Nuclear magnetic resonance (NMR) proton relaxation is sensitive to the dynamics of the water molecule, H2O, through the interaction of the spin of the proton (1H) with external magnetic and electromagnetic fields. NMR relaxation times describe how quickly the spin of 1H, forced in a direction by an external electromagnetic field, returns...
Experiment Findings
Full-text available
We report the case of a cohort of 2500 French patients treated among others with methylene blue for cancer care. During the COVID-19 epidemics none of them developed influenza-like illness. Albeit this lack of infection might be by chance alone, it is possible that methylene blue might have a preventive effect for COVID-19 infection. This is in lin...
Article
Full-text available
The enantiomerically pure ligands (1a, 1b) and the meso 1c based on the trans-1,2-cyclohexanediol and cis-1,2-cyclohexanediol respectively were used for the formation of zig-zag 1D coordination polymers, when combined with bent HgCl2. A racemic mixture or 1a/1b in 1/1 ratio has also been studied. Four 1D Coordination Polymers have been obtained and...
Article
Unresolved Anomalies Pierandrea Lo Nostro, reply by Marc Henry In response to “The Fourth State of Water” (Vol. 4, No. 4). URL = https://inference-review.com/letter/unresolved-anomalies
Article
M. Henry (2019) Water and the periodic table. Substantia 3(2) Suppl. 3: 9-11. doi: 10.13128/Substan-tia-701
Article
This article describes the formation of neutral TiO4N2-based coordination entities where the titanium centers are coordinated by oxygenated ligands incorporating one or two biphenolato units, i.e. L¹ and L² respectively. In these systems, the sixfold coordination spheres of each metallic center are completed by the enantiopure bidentate diphenyleth...
Article
Full-text available
"A scientific rationale for consciousness", Substantia 3(2): 37-54.
Article
M. Henry, "The fourth state of water" Inference : Int Rev. Sci., 4, n°4, July 2019 https://inference-review.com/article/the-fourth-state-of-water
Article
Full-text available
Abstract: From a thought experiment on the observation of a human intellect by itself, we will attempt to demonstrate that, unlike what many neuroscientists postulate, assemblies of neurons do not generate consciousness: Consciousness pre-exists any material system. Keywords: Consciousness, meaning, information, activity, neurons.
Article
Full-text available
Paper published in the Indian Journal "Homeopathy and You" Vol. 5, n°2, March 2019 (Part-1) Vol. 5, n°3, April 2019 (Part-2) Based on a conference made at the VIIth National Congress of Homeopathy, San Sebastian, Spain, May, 6-8, 2016
Article
M. Henry, "Water and its mysteries" Inference : Int Rev. Sci., 4, n°3, March 2019 URL = https://inference-review.com/article/water-and-its-mysteries
Article
In this work, we report the formation of a coloured inorganic-organic hybrid material generated from the [Ti10O12(cat)8(py)8] (catecholato (cat), pyridine (py)) oxo-cluster and poly(4-vinylpyridine). The titanium oxo-cluster is linked to the organic polymer through Ti-N coordination bonds. Vibrational spectroscopies (FT-IR and Raman scattering) and...
Article
A coordination chemistry involving trans-TiO4N2 motifs is described, where the oxygen ligands are 2,2′-biphenolato derivatives (L¹ or L²) and the nitrogen ligands are pyridine (Pyr), 2,3-dihydro-7-azaindole (DHA) or 2-(methylamino)pyridine (MePyr). Monomeric complexes and double-stranded helicates incorporating this set of ligands are characterized...
Article
Background NMR proton relaxation is sensitive to the dynamics of the water molecule H2O, through the interaction of the spin of the proton (¹H) with external magnetic and electromagnetic fields. Methods We measured dilution and potentization processes through measurements of ¹H spin-lattice T1 and spin–spin T2 relaxation times. In order to interpr...
Article
The multicomponent coordination chemistry involving Ti(OPrⁱ)4, the ortho-phenylenediamine ligand (opda) and 2,2′-biphenol-based proligands (L²H4 and L³H6) is described. The proligands L²H4 and L³H6 incorporate two and three 2,2′-biphenol units linked with p-phenylene bridges (p-PLB) respectively. We demonstrate that this selected set of components...
Article
Semi-empirical approach based on the partial charge formalism has been used to calculate 183W NMR chemical shifts in polyoxotungstates (POTs). Good consistency between calculations and experimental measurements allowed determining the main effective parameters for modeling the electronic state of the {WVIO6} centers. As the three 183W NMR chemical...
Article
Resumen Dentro del marco de la teoría cuántica, analizamos la sugerencia original de Samuel Hahnemann acerca de la existencia de una fuerza dinámica inmaterial para explicar la homeopatía. Basándonos en la teoría cuántica de campos y el concepto de los dominios de coherencia 2D, proponemos un modelo plausible de acción de los remedios homeopáticos...
Article
Full-text available
As a chemist, and somebody who has tried to promote the philosophy of chemistry, I was delighted to see Marc Henry’s article.1 As numerous authors have emphasized, chemistry, the central science, seems to have been largely neglected by philosophers of science until about the mid 1990s.2 But even in the twenty or so subsequent years the field remain...
Article
Chemistry Self-Crystallizing Pierre Laszlo, reply by Marc Henry In response to “Super-Saturated Chemistry” (Vol. 2, No. 4). URL = https://inference-review.com/letter/chemistry-self-crystallizing
Article
Journal: Inference : Int. Rev. Sci., 2[4] (2016) URL: http://inference-review.com/article/super-saturated-chemistry.
Article
Full-text available
This manuscript describes the synthesis of a series of neutral titanium(iv) monomeric complexes constructed around a TiO4N2 core. The two nitrogen atoms that compose the coordination sphere of the metallic center belong to 2,2'-bipyrimidine ligands homo-disubstituted in the 4 and 4' positions by methyl (2a), phenylvinyl (2b), naphthylvinyl (2c) or...
Article
It is suggested that electromagnetic quantum vacuum fluctuations are at the very deep root of the so-called “specific ions effects” in concentrated solutions or in living cells. A many-body quantum-mechanical frame of thinking is proposed based on the concept of quantum coherence taking into account explicitly density and excitation frequencies of...
Article
Full-text available
A series of deep-red colored nano-sized titanium oxo-clusters bearing catecholato ligands is reported. These architectures are produced via post-synthetic modification of the Ti10O12(cat)8(py)8 (cat = catecholato, py = pyridine) complex through quantitative substitution of labile pyridine ligands by three substituted pyridines (pico, 4-Phpy and pyr...
Article
Full-text available
The structural identification in solution of the Zr(iv) complexes involving two 2,2-biphenol-based proligands is reported. The proligand L(1)H2 contains one 2,2-biphenol unit whereas L(2)H4 incorporates two 2,2-biphenol units linked by a para-phenylene bridge. Diffusion Ordered Spectroscopy (DOSY) combined with electrospray mass spectrometry analys...
Article
Full-text available
The soil redox potential (Eh) can provide essential information to characterise soil conditions. In practice, however, numerous problems may arise regarding: (i) Eh determination in soils, especially aerobic soils, e.g. variations in the instrumentation and methodology for Eh measurement, high spatial and temporal Eh variability in soils, irreversi...
Article
This study aims to elucidate the interactions between water, subjected to electromagnetic waves of very low frequency (VLF) (kHz) with low strength electromagnetic fields (3.5 mT inside the coils), and the development of microbial biofilms in this exposed water. Experimental results demonstrate that in water exposed to VLF electromagnetic waves, th...
Article
M. Henry, « The hydrogen bond », Inference : Int. Rev. Sci., 1[2] (2015) URL = http://inference-review.com/article/the-hydrogen-bond.
Article
The synthesis of a bowl-shaped trinuclear circular titanium-based helicate is reported. The strategy allowing access to this neutral architecture is based on a multicomponent self-assembly approach in which the ligands involved in the process are a bis-biphenol strand and 2,2′- bipyrimidine. By reacting the bis-biphenol ligand and 2,2′-bipyrimidine...
Conference Paper
Full-text available
Water is everywhere in nature, requiring new imaging techniques for visualization of information storage or transfer in liquids or hydrated solids. Corona discharges created by exciting matter in the UV spectrum is a mean to measure in a reproducible way « bio-compatibility » between a living body and any chemical substance. In medicine, a better m...
Article
The spontaneous self-assembly of a neutral circular trinuclear Ti(IV) -based helicate is described through the reaction of titanium(IV) isopropoxide with a rationally designed tetraphenolic ligand. The trimeric ring helicate was obtained after diffusion of n-pentane into a solution with dichloromethane. The circular helicate has been characterized...
Article
We describe the synthesis and characterisation of a robust S4-symmetry titanium-based architecture bearing catecholato and pyridine ligands. This neutral complex formulated as [Ti10O12(cat)8(py)8] displays a tetrahedral inorganic core decorated by catecholato ligands with unusual coordination modes. In solution, the pyridine ligands are labile as s...
Article
We report the synthesis and structural characterisation of two titanium(IV) complexes. A new titanium(IV) complex bearing four picolinato ligands, denoted as Ti(pic)4, has been prepared under solvothermal conditions. This complex identified by single‐crystal diffraction is a new example of an octacoordinated environment for titanium(IV) and is clos...
Chapter
P. Lo Nostro & B. W. Ninham Eds In October 1611, Cosimo II De' Medici sponsored a debate in Florence starring Galileo on "Why ice floats on water." 400 years later 25 scientists commemorated the event, revisiting all things to do with water: modern views on Galileo, fresco restoration, cement. Water, its history, in jellyfish; solutions of salts an...
Chapter
P. Lo Nostro & B. W. Ninham Eds In October 1611, Cosimo II De' Medici sponsored a debate in Florence starring Galileo on "Why ice floats on water." 400 years later 25 scientists commemorated the event, revisiting all things to do with water: modern views on Galileo, fresco restoration, cement. Water, its history, in jellyfish; solutions of salts an...
Article
Full-text available
The consumption of alkaline reduced water produced by domestic electrolysis devices was approved in Japan in 1965 by the Ministry of Health, Labour and Welfare for the cure of gastro-intestinal disorders. Today, these devices are freely available in several countries and can be easily purchased without reserve. The commercial information included w...
Article
X-ray diffraction analysis of cyclometalated, chiral-at-metal rhodium and iridium complexes with the general formula [Cp*MCl{κ2(N,C)-(2-phenyl-2-imidazoline}] reveals that they undergo noncovalent self-assembly through intermolecular NH···Cl hydrogen bonding and, in some cases, CH/π interactions. Compound (±)-6b coordinated with an unsubstituted, a...
Article
The work presented here concerns the evaluation of the reactivity of the [Ti8O8(OOCCH2But)(16)] cluster towards phenol, resorcinol and catechol using NMR techniques. Whereas the reactions conducted in the presence of phenol and resorcinol showed to be particularly slow, it appeared that catechol allowed the quantitative displacement of the carboxyl...
Article
We described the development of a set of highly symmetric multitopic oligophenylene molecules decorated with hydroxyl functions that are all derived from the resorcinol moiety. All these resorcinol-based oligophenylene self-assembled structures and the corresponding methoxy protected precursors were found to be highly crystalline materials, with tw...
Article
Full-text available
We examine in some detail the interaction of water molecules with the radiative electromagnetic field and find the existence of phase transitions from the vapor phase to a condensed phase where all molecules oscillate in unison, in tune with a self-trapped electromagnetic field within extended mesoscopic space regions (Coherence Domains). The prope...
Article
a] Keywords: Titanium / N ligands / Bond energy / Thermodynamics A rational approach leading to a novel family of monomeric heteroleptic titanium complexes formed with two biphenol-ate derivatives and six different bidentate nitrogenated che-lates is proposed. Only one case of loss of structural predict-ability was observed in the case of a N,O-coo...
Article
Well-defined biphenol/binaphtolate group 4 alkoxide salt species [(Ph-Biphen-O)(2)M(O(i)Pr)]Li(THF) (2a, M = Ti; 4a, M = Zr) and [(Ph-binapht-O)(2)M(O(i)Pr)]Li(THF) (2b, M = Ti; 4b, M = Zr) were found to be readily accessible in good yields via alcohol elimination routes and/or substitution reactions from the corresponding pro-ligands Ph-Biphen-OH...
Article
The asthma therapeutic theophylline exists in at least three anhydrous polymorphs and a monohydrate. The single-crystal X-ray structure of the high-temperature polymorph form I is presented for the first time, and the energetic relationship between forms I and II is investigated using the partial charges and chemical hardness analysis (PACHA) algor...
Article
A new class of organic crystalline 2,2'-biphenol-based H-bonded material displaying 1D-channels encapsulating solvent molecules is described. A reversible guest-induced crystal-to-crystal conversion between the solvated H-bonded phase and a compact H-bonded non-solvated phase was observed. The energy competition between intramolecular H-bonds forma...
Article
The force of water like the Captain Cook Memorial Fountain in Canberra (Australia), has been investigated in three polymorphs of highly hydrated p-sulfonatocalix[4]arene tetrasodium salt. Single-crystal neutron structures reveal a “compressed” water molecule with short OH bonds, and PACHA calculations give an OH⋅⋅⋅π interaction energy of 6.9–7.5 kJ...
Article
Tetrasodium p-sulfonatocalix[4]arene exists as a hydrate with approximately 14 water molecules and has three polymorphic modifications, all of which contain a water molecule in the molecular cavity that is engaged in OH···π interactions. Single-crystal neutron structures are reported for two of these three forms and reveal a "compressed" water mole...
Article
Here we describe the fabrication and characterization of selective nanocomposite membranes based on ethylene–vinyl alcohol copolymers and polyoxomolybdate clusters. Larger “buckyball”-type polyoxomolybdates have been shown to display hydrophilic pores which allow the transport of water molecules but prevent the passage of larger, hydrophobic molecu...
Article
Two nanosized zigzag-shaped oligophenylene strands incorporating 2,2'-biphenol units were prepared by Suzuki-Miyaura coupling methodology. The two strands are made up of ten and seven phenyl rings, respectively. Two synthetic pathways were evaluated. The first involved the preparation of the target oligophenylene molecules by a sequential approach,...
Article
We report the hydrothermal synthesis, X-ray crystal structures, and thermal, optical, and magnetic properties of two isostructural layered coordination polymers, [M(II)(5)(OH)(2)(chtc)(2)(H(2)O)(10)]·2H(2)O where M = Co (1Co) or Ni (2Ni) and chtc = cis,cis,cis-1,2,4,5-cyclohexanetetracarboxylate. The structures consist of segregated layers where ea...
Article
A binuclear Ti(IV)-based helicate synthesized from a symmetric tetrahydroxyheptaphenylene strand was self-assembled in solution and shown to undergo a spontaneous head-to-tail differentiation according to single-crystal X-ray diffraction.
Article
The orange-colored and hydrolytically stable compound {[Ti2O(Hbhmpc)(H(2)bhmpc)(H(2)bhmpc)] C4H8O2 HX}(2) (with H(3)bhmpc = 2,6-bis(hydroxymethyl)-p-cresol and X = OEt or CCl3) has been studied by a combination of single crystal Xray diffraction data, U V-vis. spectroscopy, IR and Raman spectroscopes, H-1, C-13 and O-17 solution NMR spectroscopes,...
Article
The 3,3'-diphenyl-2,2'-biphenol (dpbpolH(2)) ligand is shown to react with Ti(OPr(i))(4) in a 2:1 ratio to yield a novel C(2)-symmetric mononuclear octahedral Ti(IV) bis-biphenolate complex, cis-Ti(dpbpol)(2)(HOPr(i))(2).
Article
Full-text available
Among all the chemical substances available in the universe, water, with its deceptively simple formula H2O, is the most discussed subject either in science or in philosophy [1]. If you are not convinced by this affirmation, a little experiment at no cost may help you change your mind. Just open your favorite web browser and type the word “water” i...
Article
Using a combination of charge-assisted H- and coordination-bonds, a tetra component system composed of a dicationic and a dianionic organic tecton, Ag(+) cation and XF(6)(-) (X= P, As, Sb) anion behaves as planned and leads to the formation of 2-D isostructural networks for which the energetic contributions of the two recognition events dominate th...
Article
The Stokes-Einstein expression of the diffusion coefficient as a function of the hydrodynamic radius of the diffusing object does not explicitly carry the mass dependency of the object. It is possible to correlate the translational self-diffusion coefficients D with the molecular weight M for an ensemble of cyclic or hollow clusters ranging from ab...
Article
The surface energy of some clays belonging to the smectite group has been calculated starting from crystal structures and combining a partial charge model with the computation of the lattice energy. The dioctahedral smectites studied here include montmorillonite; beidellites; and nontronite. One of the differences between these clays is the locatio...
Article
The ionic recognition properties of neutral oxothiomolybdenum wheels can be changed from anionic to cationic through ionization of the internal aquo ligands. In the solid state, [Mo8O8S8(OH)10(H2O)]2- (1) interacts with two Cs+ cations to give a close supramolecular host-guest arrangement. Such interactions appear to be maintained in solution as a...
Article
Stuck in the middle with you: The spherical cluster {(Mo)Mo 5}12Cr30 (1) fills, with its spin, a gap in the series of the analogous Fe (S = 5/2) and V (S = 1/2) clusters. This allows a deeper understanding of the magnetic properties of the series members, particularly with reference to geometric frustration, also found in the famous Kagomé lattices...
Article
The enthalpy produced during immersion in water of a smectite, identified as a montmorillonite, substituted by Ca or Na is analyzed using three different approaches. The heat of immersion is measured using the classical calorimetric method. It is compared to an estimate using adsorption techniques. And it is calculated from a theoretical estimate o...
Article
The surface energy of exchanged forms of montmorillonite has been computed using a partial charge model introduced in the calculation of the lattice energy. The results are in correct agreement with data on heats of adsorption. However, the difference between theoretical and experimental data increases from light cations to heavy cations associated...