Manuel Ignacio Azocar

Manuel Ignacio Azocar
University of Santiago, Chile | USACH · Facultad de Química y Biología

Ph. D

About

50
Publications
21,730
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941
Citations
Introduction
He is currently Research Assistant of Chemistry at University of Santiago of Chile and his main research interests focus on the study and development of antibacterial inorganic materials, among others. https://azocargrouplab.org/
Additional affiliations
March 2008 - present
University of Santiago, Chile
Position
  • Professor (Assistant)
March 2008 - present
University of Santiago, Chile
Position
  • Professor (Assistant)
Description
  • He is currently Research member of The Center Of Soft Matter Research (SMAT-C). His main research interests focus on the study and development of antibacterial inorganic materials, among others.
Education
March 1993 - December 2020
University of Santiago, Chile
Field of study
  • Chemistry

Publications

Publications (50)
Article
Full-text available
The influence of pH on the electrochemical behavior of hydrogen peroxide in the presence of Pseudomonas aeruginosa was investigated using electrochemical techniques. Cyclic and square wave voltammetry were used to monitor the enzymatic activity. A modified cobalt phthalocyanine (CoPc) carbon electrode (OPG), a known catalyst for reducing O 2 to H 2...
Article
AISI 430 stainless steel is an attractive material to be used in the healthcare industry, particularly as a sensor due to its low cost, corrosion resistance, as well as being Ni-free. AISI 430 was evaluated in an artificial sweat solution with the presence of Escherichia coli, and Staphylococcus aureus. Surface microbial analyses did not reveal col...
Article
Ti-6Al-4V alloy has been widely investigated for biomedical applications due to its low density, high specific strength, and favorable corrosion resistance. However, some reported failures have imposed a challenge to improve bone regeneration and fixation, as well as antibacterial properties. A further opportunity for solving this problem is the in...
Article
New experimental techniques and protocols are needed to study microbiologically influenced corrosion (MIC). In this work, we studied the capacity of microorganisms to modify their environment in vitro. The methodology involved cyclic voltammetry measurements using carbon electrodes modified with cobalt phthalocyanine, which is a known catalyst for...
Article
Full-text available
Silanol type hybrid polymers modified with silver nanoparticles encapsulated with SiO2 for biocorrosion protection of 2024-T3 aluminum alloy were studied through electrochemical characterization and surface analysis techniques. Two different encapsulated silver nanoparticles were synthesized using tetraethoxysilane as a core shell. The hybrid polym...
Article
Full-text available
Silver nanoparticles (AgNPs) have been widely recognized as antibacterial agents. However, its stability and activity over time have been poorly studied. In this work, the properties and characteristics of differently stabilized AgNPs were evaluated during a span of time. The surface capping agents were diclofenac (d), and ketorolac (k), which curr...
Article
Full-text available
An experimental protocol was studied to improve the adhesion of a polymeric poly(methyl methacrylate) coating that was modified with silver nanoparticles to an aluminum alloy, AA2024. The nanoparticles were incorporated into the polymeric matrix to add the property of inhibiting biofilm formation to the anticorrosive characteristics of the film, th...
Article
Full-text available
The antibacterial effects against Staphylococcus epidermidis of five silver carboxylate complexes with anti-inflammatory ligands were studied in order to analyze and compare them in terms of stability (in solution and after exposure to UV light), and their antibacterial and morphological differences. Four effects of the Ag-complexes were evidenced...
Article
Full-text available
Background: Current knowledge of urban bird ecology and biodiversity relies on evidence from cities of the Northern Hemisphere, while the Southern Hemisphere is underrepresented. Santiago is a large city from South America, located in central Chile, which is both a biodiversity hotspot and an Endemic Bird Area. This work is a synthesis, which aims...
Article
Bond nature of carboxylic groups can play an important role in Ag(I)-carboxylate compounds because light and thermal stability are important requirements for future applications such as antibacterial additives. A linear correlation between bond character and light stability of silver carboxylate complexes has been predicted by a direct relationship...
Article
Full-text available
In Chile the White-banded Mockingbird (Minus triurus) is considered an occasional visitor although it has been reported more frequently during the last eight years (2005-2013). This is probably due to the increased number of birdwatchers in the field and to the dissemination of records by means of digital media. Information collected since 1932 all...
Article
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In this study, an antibacterial, but not cytotoxic nanomaterial based on polyethylene and copper nanoparticles was prepared by in situ polymerization. PE–CuNps nanocomposites against Escherichia coli, completely suppressed the number of live bacteria after 12 h incubation compared to neat PE. TEM images showed that nanocomposites damage the plasma...
Article
Full-text available
Since ancient times, silver ions have been known to be effective against a broad range of micro-organisms but in the last decade, this metal has been greatly studied because of their antimicrobial capability against a wide range of bacteria, viruses, and fungi. For the same reason, it is the most extensively studied metal with antibacterial applica...
Article
Full-text available
We report here a systematic study of the antibacterial behavior of silver nanoparticles coated with fatty acids (oleic: AgNP-O, linoleic: AgNP-L, and palmitic acids: AgNP-P) in water. We have found remarkable differences in their capability to penetrate bacteria cell over a broader range of particle size of similar to 4-96 nm compared to previously...
Data
Since infection is a major cause of death in a patient whose immune responses have been compromised (immu-nocompromised patient), considerable attention has been focused on developing materials for the prevention of infections. This has been directed primarily at suppressing or eliminating the host's endogenous microbial bur-den and decreasing the...
Article
Antibacterial properties of silver(I)-pyridinedicarboxylate compounds (with Pyridine-2,3-dicarboxylic(Lutidinic acid), pyridine-2,4-dicarboxylic (Quinolinic acid) and pyridine-2,5-dicarboxylic (Isocinchomeronic acid)) were studied against Escherichia coli, Listeria monocytogenes (ISP-65-08), Salmonella typhi and Staphylococcus aureus (ATCC 25923) u...
Article
Full-text available
The antibiofouling ability of three hybrid sol-gel coatings against P. aeruginosa for the protection of AA2024-T3 aluminium alloy has been investigated. The polymers were synthesized by mixing tetraethoxysilane (TEOS) with three precursors: (a) triethoxypropylsilane (TEPRS), (b) triethoxypentylsilane (TEPES) and (c) triethoxyoctylsilane (TEOCS). Th...
Article
Full-text available
Five water soluble silver(I) complex with Ibuprofen (AgIbu), Naproxen (AgNap), Mefenamic acid (AgMef), acetyl salicylic acid(AgAsp) and salicylic acid (AgSal) were synthesized and characterized by elemental analysis, FT-IR, 1H and 13C NMR. Data suggest coordination of the ligand to Ag(I) through the oxygen atom of the carboxylic group. AgAsp was ob...
Article
Full-text available
Every chemist has at some time synthesized a compound, because synthesizing is thebeginning of all subsequent studies. It does not matter if the applications includemedicine, engineering, food, energy, or it is just the interest in creating new molecules.Most discoveries in chemistry include the synthesis of new materials and everyday new compounds...
Article
Full-text available
The antimicrobial effect of incorporating silver nanoparticles (AgNps) into zirconia matrixepolyether glycol was studied. AgNps of 4e6 nm in size were synthesized using the inverse micelles method, and different doses of metallic nanoparticles were incorporated into zirconiaepolyether glycol mixtures during the ageing procedure. Atomic force micros...
Article
Full-text available
The aim was to study if the antimicrobial activity of chitosan incorporated into edible films based on gelatin could be affected by the molecular mobility (glassy or rubbery state) of the matrix. Films were obtained from film-forming suspensions (FFS) of bovine and salmon gelatins (7% w/w) and chitosan (0; 0.25; 0.5; 1% w/w) equilibrated at 33% y 8...
Data
FT-IR spectroscopy of carboxylic groups and viability tests were useful to understand the antibacterial proper-ties of six highly efficient silver(I) pyridinecarboxylate (nicotinic, picolinic and isonicotinic acids) and bipiridine-carboxylate (pyridine-2,3-dicarboxylic, pyridine-2,4-dicarboxylic and pyridine-2,5-dicarboxylic acids) complexes with A...
Article
Full-text available
Salmon gelatin and chitosan are high potential biopolymer to obtain edible films with antimicrobial effect for fresh meat. Therefore, it is important to characterize the structural (glassy or rubbery) state of the gelatin film on antimicrobial properties of chitosan. Extracted salmon (Salmo Salar) gelatin (acid-basic extraction) and low molecular w...
Article
A new hybrid sol–gel type film, composed of tetraethylorthosilicate (TEOS) and tetraocthylorthosilicate (TEOCS), and modified with different nanoparticle systems, has been investigated as a coating for protection of AA-2024-T3 aluminium alloy. The nanoparticle systems considered were either ZrO2 or CeO2 or their combination. The zirconia nanopartic...
Article
Polyethylene nanocomposites containing silver nanoparticles with antimicrobial properties were produced via in situ polymerization. The silver nanoparticles were added together with the catalytic system (metallocene catalyst and methylaluminoxane, MAO, as cocatalyst) directly to the reactor. The polymerization activity did not present significant c...
Article
Full-text available
In this study, we compared four glassy carbon electrodes modified with adsorbed porphyrins of cobalt containing one, two, three, or four bis(methoxyphenyl) groups as substituents of the ligand. The aim of this work was to determine the effect of these donating groups on the electrocatalyst behavior of the modified electrodes for the reduction or ox...
Article
Full-text available
5,5'-Dialkyl-6,6'-dichloro-2,2'-bipyridines were synthesized starting from 3-substituted 2-chloro-6-iodopyridines using Pd-catalyzed coupling conditions. 6-Alkyl-3,5-dichloro-2H-1,4-oxazin-2-ones were excellent precursors for the synthesis of these functionalized 2-iodo-6-chloropyridines.
Article
Full-text available
Three glass electrodes covered with Co-cobaltite/SnO2:F (to obtain conducting glass electrodes) modified with p-Ni-tetraaminophenylporphyrin are described. In one electrode the porphyrin was absorbed on the electrode surface at room temperature, in another the porphyrin was electropolymerized on the electrode surface by cyclic voltammetry, and in t...
Article
Full-text available
5,15-Bis(veratryl)porphyrin (1), 5,10,15-tris(veratryl)porphyrin (2), and 5,10,15,20-tetrakis(veratryl)porphyrin (3), C36H30N4O4, C44H38N4O6, and C52H46N4O8 were synthesized by an acid-catalyzed, one-pot reaction of meso-dipyrromethane, 3,4- di-OCH3-benzaldehyde (veratraldehyde), and trifluoroacetic acid (TFA). These three different products were o...
Chapter
Full-text available
The use of fossil fuels in the past century has generated a continuous increase in the carbon dioxide atmospheric concentration, creating the greenhouse effect, which produces undesirable changes in the global climate1. Carbon dioxide is a small molecule of utmost importance for the production and/or energy storage in nonconventional resources. Its...
Article
The photochemical and photophysical properties of the (CO) 3 (biq)Re I (4,4′-bipy)Ru II (biq)(CO) 2 -Cl 2+ and (CO) 3 (biq)Re I (pz)Ru II (biq)(CO) 2 Cl 2+ dyads and the monometallic compounds Re I -(biq)(CO) 3 (4,4′-bipy) + , Re I (biq)(CO) 3 (pz) + , and Ru II (biq)(CO) 2 Cl 2 have been investigated. Deaerated solutions of these compounds were ir...
Article
The electro-oxidation of sulfite was studied by using a glassy carbon electrode coated with a polymeric film of Fe-tetra-4-aminophenylporphyrin, in a wide pH range. The polymeric complex-modified electrode catalyses the electro-oxidation of sulfite to sulfate in acid and basic media, but it is more active at pH higher than 8.5. The polymer film coa...
Article
Full-text available
In this paper we present a simple and mild procedure to incorporate cations of transition metals to a polymer of the free-ligand para-tetraaminophenylporphyrin (H2TAPP) in order to obtain similar responses as in the case of the direct electropolymerization of a metallic complex. Sometimes, it is not possible to obtain an electropolymerized complex...
Article
Full-text available
with carbonyl and polypyridyl ligands derived from and polypyridyl ligands derived from dipyrido[3,2-dipyrido[3,2-a a:2 :2' ',3 ,3' '--c c]phenazine: application to the ]phenazine: application to the water gas shift reaction water gas shift reaction The preparation and spectroscopic properties of new dipyrido[3,2-a:2',3'-c]phenazine ruthenium compl...
Article
Full-text available
A new Rhenium (I) and Ruthenium(II) bimetallic polipyridilcarbonil complex and the corresponding monometallic precursor complexes were prepared. The compounds were characterized physically and spectroscopically (Elemental Analysis, Conductivity, Cyclic Voltammetry, IR-FT, RMN-H and UV-Visible). The results are consistent with the [Re(CO)3(2,2′-biqu...
Article
The fac-MnBr(CO)3(3,3′-R-2,2′-biquinoline) (R=CH3 and CH3; H and H; CH2CH2 or CH2CH2CH2) compounds were synthesized and characterized. The fac-conformation for the carbonyl complexes was established by IR spectroscopy. Conformational effects were investigated by means of 1H NMR and UV–Vis spectroscopical and electrochemical properties and th...

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Projects

Projects (3)
Archived project
The main objective of this project is to generate a green anticorrosive coating, which emulates the excellent properties of chromium-based ones, highly compact, with excellent adhesion to the metal substrate, with self-healing ability and powerful as a bactericide.
Project
To better understand the initiation and development of the corrosion of Ti-based alloys employed for biomedical applications exposed to simulated biological solutions