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Manjit Singh Bal

Manjit Singh Bal
MMM C & H Solan Former Government Medical College, Patiala · PATHOLOGY

MBBS; MD (Path); FICP; PMES-I

About

123
Publications
48,564
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Citations
Introduction
Former head Path GMC Patiala from Aug. 1998 to March 2015, Currently prof. Path at MM Med College Kumarhatti Solan. Produced over 110 PG’s, Authored 11 books on health & literary. Visits USA, Canada, Singapore, Australia, Nepal, Bangladesh, Pakistan. Examinership- 18 Indian Universities. Write in Punjabi, Hindi & English. Radio & TV talks-Health, cancer awareness. Hobbies: Instrumental music & singing. A feature films:1) "Musarrat" & 2) Jhanjar with osteosarcoma
Additional affiliations
June 2012 - present
Government Medical College, Patiala
Position
  • Development of an Atlas of Cancder in Punjab
June 2011 - present
Government Medical College, Patiala
Position
  • Development of an Atlas of Cancer in Punjab
August 1998 - March 2015
Government Medical College, Patiala
Position
  • Govt. Medical College Patiala Punjab
Education
July 1985 - June 1987
Govt. Medical College, Guru Nanak Dev University Amritsar
Field of study
  • Pathology
July 1971 - December 1976
Government Medical College, Guru Nanak Dev University, Amritsar ,
Field of study
  • Medical Sciences

Publications

Publications (123)
Article
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Signet ring cell carcinoma constitute an uncommon histological type of rectal cancer with less than 1% of all rectal neoplasms. It usually behaves aggressively and has an inferior prognosis. Herein, we present a rare case in young male diagnosed by trucut biopsy.
Article
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Lymphoma constituting 55.6% of hematological malignancy, its prognosis depends on the correct diagnosis and stage of the disease, which is established after examination of peripheral blood film (PBF), bone marrow aspiration (BMA) and bone marrow biopsy (BMB) along with other parameters. The objective is to find out the percentage and pattern of bon...
Presentation
Biomarkers are produced by cancer cells or other cells in response to cancer or some other conditions. These are also produced by normal cells, however higher levels appear in malignancy. Most biomarkers are proteins though recently, patterns of gene expression and changes in DNA have also begun to be used as tumor markers. Various biomarkers are i...
Poster
Tissue eosinophilia has been demonstr ated under physiological conditions in spleen, digesive track, lactating mammary gland, serous membranes and loose connective tissues of mammals. Such an eosinophilia though slight, has been demonstrated in human uterus. A 48 year para 2, gravida 2, with a scar of lower segment caesarean section (LSCS), present...
Article
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Background: Previous efforts to report estimates of cancer incidence and mortality in India and its different parts include the National Cancer Registry Programme Reports, Sample Registration System cause of death findings, Cancer Incidence in Five Continents Series, and GLOBOCAN. We present a comprehensive picture of the patterns and time trends...
Article
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Background Micro RNAs (miRNAs) are small, noncoding RNA molecules. They can function as either oncogenes or tumor suppressor genes. Single nucleotide polymorphisms (SNP) present in the pre-miRNA region could affect the processing of miRNA and thus alter mature miRNA expression. The studies done so far had shown conflicting results regarding associa...
Article
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Objectives: Ever since the discovery of Mycobacterium tuberculosis in 1882, many diagnostic methods have been developed. However “The gold standard” for the diagnosis of tuberculosis (TB) is still the demonstration of acid fast Bacilli (AFB) by microscopic examination of smear or bacteriological confirmation by culture method. Materials and Methods...
Data
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Article
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Peripheral blood examination has been a window for hematological assessments since decades. Blood smear is often used to categorize and/or identify conditions that affect one or more types of blood cells. Examples include anemias, various infections, myeloproliferative disorders, thrombocytopenias and leukemias. To study the prevalence of various h...
Article
The heart is a structurally equipped and well functioning muscle, which sustains life. Most of the myocardium depends on nutrients and oxygen delivered by the coronary arteries. Coronary artery diseases are the leading cause of death worldwide. This study on pathological findings in coronary arteries, in post mortem cases was done in the department...
Article
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The State of Punjab has been in focus because of aperceived increasing rate of cancer. Both print and electronic media have created an impression that Punjab, especially the cotton belt of Malwa Region, has become a high incidence cancer region. Actually the increased number of cancer patients might be at least partly because of increasing populati...
Article
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The most common cause of acute abdomen even today is acute appendicitis. An inflammatory disorder, several laboratory factors contributing to its inflammatory responses are used for diagnosis. To estimate the value of ESR, CRP, TLC and DLC in 200 suspected patients of acute appendicitis in both sex of different age groups. The present study were pe...
Article
Full-text available
Objectives: Ever since the discovery of Mycobacterium tuberculosis in 1882, many diagnostic methods have been developed. However 'The gold standard' for the diagnosis of tuberculosis (TB) is still the demonstration of acid fast Bacilli (AFB) by microscopic examination of smear or bacteriological confirmation by culture method. Materials and Methods...
Conference Paper
Full-text available
Globally, cancer of cervix is second most common cancer in women, while it is number one female cancer in developing nations.1 Pap smear is a tool for screening “invisible” cervical abnormalities under light microscopy. Cervical cancers are preceded by long standing precancerous lesions. These lesions exist in the non-invasive stage for years and s...
Conference Paper
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Aspergillosis is an infection caused by fungus aspergillus fumigatus which primarily occurs in patients with severe immunodeficiency. Most common site of infection is respiratory system. Incidence rate is approximately 1-2/100,000 per year: and in rare cases, there can be co-existing tuberculosis.
Conference Paper
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The spectrum of pulmonary involvement includes leukemic infiltrates (extramedullary hematopoiesis), infections haemorrhage, leukostasis, leukamic cell lysis, pleural effusion, pulmonary hypertension, hyperleucocytic reaction and alveolar proteinosis.
Conference Paper
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Myocarditis is inflammation of myocardium. The exact incidence of myocarditis is unknown.
Conference Paper
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Lymphoma is a primary malignant neoplasm of the lymphoid tissue which constitutes 55.6% of all haematological malignancies. Non-Hodgkin Lymphoma (NHL) is more common (87.4% of all lymphoma) than Hodgkin Lymphoma (HL) (12.6%) Peripheral blood smear, bone marrow aspiration and biopsy are routinely performed to diagnose lymphoproliferative disorders....
Article
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Background: Leprosy continues to be a predominant public health problem in India despite rapid strides made for its prevention, detection and treatment since ages. As leprosy can occur in any form due to immunological status of the patient, its clinico-pathological correlation gains more importance. Aim : The present research was undertaken to asce...
Article
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Abnormal uterine bleeding and infertility are among the commonest conditions for which patients seek advice in the gynecological outpatient department.Endometrial biopsy is currently the most commonly used technique for histological evaluation of endometrial pathology. The study was aimed to find the incidence of various pathological lesions of end...
Article
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Conclusion: The study favored the non-obstructive inflammatory theory initiated by mast cells in preference to the obstructive theory for the causation of appendicitis.
Article
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A perplexing diagnostic and therapeutic dilemma is often presented by masses involving glandular and nodal structures of head and neck - lymph nodes, thyroid gland and salivary glands. Fine needle aspiration of such masses is a rapid, direct and safe adjunctive surgical procedure for obtaining material for cytologic analysis
Article
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Primary testicular non-Hodgkin lymphoma (NHL) is an uncommon extra nodal presentation, constituting 1% of all NHL, majority of which are B-Cell type, with only very few cases of primary T-Cell lymphoma. A 60 years male presented with asymptomatic unilateral testicular swelling. Ultrasonography revealed a heterogeneous testicular mass in relation to...
Article
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Lesions of male genital tract form a relatively small but highly important part of pathological practice. They constitute a group of lesions which are difficult to detect and treat because of their anatomical locations, biological characters as well as their implications. To study the frequency of lesions of male genital tract. The prospective stud...
Article
Primary splenic tumours are very rare. Occurrence of primary splenic Hodgkin's Lymphoma is particularly unusual. A 22 year old male presented with the complaints of fever, generalised weakness and mild left upper quadrant pain, had massive splenomegaly on examination. Laboratory investigations persistently revealed pancytopenia. A diagnosis of hype...
Article
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Primary splenic tumours are very rare. Occurrence of primary splenic Hodgkin's Lymphoma is particularly unusual. A 22 year old male presented with the complaints of fever, generalised weakness and mild left upper quadrant pain, had massive splenomegaly on examination. Laboratory investigations persistently revealed pancytopenia. A diagnosis of hype...
Article
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It is rare to find simultaneous benign cystic teratoma and pregnancy luteoma in an ovary. Mature cystic teratoma is the most common type of ovarian germ cell neoplasm. About 0.8% to 12.8% of reported cases of mature cystic teratorma have occurred during pregnancy. Pregnancy luteoma is a distinctive, non - neoplastic lesion of pregnancy, characteriz...
Article
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Introduction: Sex chromatin is a plano-convex to triangular DNA mass measuring approximately 1µm in size and lying adjacent to the inner side of nuclear membrane in the somatic cells of the females. There is consistent loss in the sex chromatin percentage in the carcinoma cases in comparison to benign lesions and normal individuals. Aim: To know th...
Article
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ABSTRACT Background: Infertility is defined as failure to conceive within one or more years of regular unprotected coitus. The infertility state is dependent on the female factor as well as masculine factor; an altered masculine factor is designated when any cause or causes of infertility reside in the male. The masculine factor as a cause of...
Article
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Ovarian lesions frequently form a pelvic mass and are associated with abnormal hormonal manifestations. Clinically and surgically they potentially mimic ovarian neoplasms but pathologically they can be classified into non neoplastic cysts, inflammation and neoplasms. Objective of the study was to determine the nature, frequency and distribution of...
Article
Lesions involving oral cavity are very common in India especially in areas where tobacco, paan and related products are extensively used. Tongue, lips, floor of mouth, hard & soft palate, gingiva and buccal mucosa are usually involved. The aim and objective of study is to determine the frequency of these lesions and categorize them based on biopsie...
Article
Struma ovarii or monodermal teratoma, is a specialized ovarian neoplasm composed entirely of mature thyroid tissue. It is a relatively rare tumor which comprises 1% of all ovarian tumors and 2.7% of all dermoid tumors. Its colour and consistency is like that of a thyroid tissue. The tissue may show any of the pathologic changes seen in a normally p...
Article
Full-text available
Background: Prostate cancer is an important growing health problem presenting a challenge to urologists, radiologists, pathologists, and oncologists. Many men have incidental microscopic foci of prostate cancer at postmortem that did not manifest during life time. However, some cancers are aggressive with a rapidly worsening course. The objective o...
Conference Paper
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This study was conducted in order to determine the histopathological prevalence of coronary atherosclerosis in the general population.
Conference Paper
Full-text available
Every since the discovery of Mycobaterium tuberculosis in 1882, many diagnostic methods have been developed. However " The gold standard" for the diagnosis of tuberculosis is still the demonstration of AFB by microscopic examination of smear, or a bacteriologic confirmation by culture method.
Conference Paper
Full-text available
Carcinoma breast with neuroendocine features is a variant of invasive ductal carcinoma of breast. 75% of invasive ductal carcinoma are generally designated as invasive ductal carcinoma of classic or not-otherwise- specified(NOS) type.
Conference Paper
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HER2/neu, a proto-oncogene, also known as erbB2, Plays and important role in the causation and prognosis of breast cancer
Conference Paper
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Human cysticercosis is the parasitic infestation caused by the larvae of pork tape worm Taeniasolium through contaminated food and water of dirty hands. Although it can affect any organ or tissue of the body, the most common sites are the muscles and subcutaneous, brain, muscles, heart, liver, lungs andperitoneum.
Conference Paper
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Chemodectoma is rare tumor of neuroendocrine tissue of carotid body. In most of cases it is benign but can be malignant. A superficial parotidectomy specimen was received in department of Pathology, Government Medical College, Patiala. Histopathological examination revealed chemodectoma,
Conference Paper
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Lymphomas of intra parotid lymph nodes are uncommon and comprise 0.6-5.0% of all parotid tumors. Of all parotid malignant lymphomas, majority are B cell non- Hodgkin lymphomas(84-97%), while only 3-16% are Hodgkin type, very exceptionally T cell type.
Conference Paper
Full-text available
It is a rare to find simultaneous benign cystic teratoma and pregnancy luteoma in an ovary. Mature cystic teratoma is the most common type of ovarian germ cell neoplasm. About 0.8% to 12.8% of reported cases of mature cystic teratorma have occurred during pregnancy. Pregnancy luteoma is a distinctive, nonneoplastic lesion of pregnancy, characterize...
Conference Paper
Full-text available
Primary Malignant lesions of the vagina represent less than 2% of all gynaecologic malignancies. Vaginal sarcomas account for about 2% of all malignant vaginal lesions: Leiomyosarcoma being the most common vaginal sarcoma found in adult women.
Conference Paper
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Neuroendocrine tumours of rectum constitute about 19% of gastrointestinal neuroendocrine tumours. Rectal neuroendocrine carcinoma is rare with aggressive behaviour and poor prognosis. Aggressive neuroendocrine tumours of colon and rectum account for 4% of all colorectal carcinoma. An intestinal neuroendocrine carcinoma has no specific signs in earl...
Conference Paper
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Malignant pleural effusions are commonly caused by carcinomas of the lung, breast, gastrointestinal tract, ovaries and lymphomas. In males about half are caused by lung cancer, and in females, about 40% are caused by breast cancer. Common are group of lung cancer is 40-80 years, only less than 10% occur below 30 years.
Article
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Ascites is a common clinical finding with a wide range of causes. Ascites refers to collection of excess fluid in the peritoneal cavity. It is clinically important to classify ascitic fluid into transudates and exudates because it is indicative of the underlying pathological process involved. The present study aims at evaluating the pathologica...
Article
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A 50–year old female presented with the chief complaint of a discharge per vaginum, which was there for the past 15 days. A routine PAP smear was received in the Department of Pathology, Government Medical College, Patiala, India. After its fixation and staining, it was examined under the microscope. It showed the Trichomonas vaginalis infection, w...
Article
Full-text available
Background: FNAC is an inexpensive and highly accurate means of diagnosing both benign and malignant breast lesions. The procedure provides a rapid and non-morbid diagnosis before the operation which enables the patient and the surgeon to discuss and plan therapeutic alternatives in a rational atmosphere. Objectives: To evaluate role of fine n...
Article
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Ovarian germ cell tumours comprise approximately 15% to 20% of all ovarian neoplasms. In pregnant females, its incidence is very low. They arise from primordial germ cells derived from the embryonal gonad. Malignant germ cell tumours comprise less than 5% of all ovarian neoplasms. Most malignant ovarian neoplasms in pregnant women are at early...
Article
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Unlabelled: The larynx serves to protect the lower airways, facilitates respiration and plays a key role in phonation. Based on anatomic location, the larynx is divided into the supraglottic larynx, the glottis or glottic larynx, and the subglottic larynx. The tumours of larynx can be divided into benign or malignant. Laryngeal granulomas, Vocal c...
Article
Full-text available
Xanthogranulomatous oophoritis is an unusual chronic inflammation and clinically it form a mass-like lesion in the pelvic cavity and invades the surrounding tissue which mimic the tumour. Histologically, it is characterized by the presence of lipid filled macrophages with admixed lymphocytes, plasma cells and neutrophils. Granulomatous change ocurr...
Conference Paper
Full-text available
Sex chromatin is a plano-convex to triangular DNA mass measuring approximately 1um is size and lying adjacent to the inner side of nuclear membrane in the somatic cells of the females. There is consistent loss in the sex chromatin percentage in the carcinoma cases to know the correlation between lesions and normal individuals.
Conference Paper
Full-text available
Human Cysticercosis is the infection caused by larva of cestode family. pork tapeworm taenia solium. Cysticercosis may be found in any organ, most common sites are the muscles, brain, skin, and heart. Involvement of breast is rare presentation.
Conference Paper
Full-text available
Struma ovarii or monodermal teratoma, is a specialized ovarian neoplasm composed entirely of mature thyroid tissue. It is a relatively rare tumour which comprises 1% of all ovarian tumours and 2.7% of all dermoid tumors. It s color and consistency is like that of a thyroid tissue. the tissue may show any of the pathologic changes seen in a normally...
Conference Paper
Full-text available
xanthogranulomatous oophoritis is an uncommon, non-neoplastic, chornic process in which tissue of the affected ovary is destroyed and replaced by a striking cellular infiltrate of foamy histiocytes, admixed with plasma cells, giant cells, fibroblasts, neutrophils and foci of necorsis. Its etiology is unknown and mostly affects females in their thir...
Conference Paper
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Gyanecological malignancies frequently occur during reproductive age of women and are estimated to complicate approximately one in 1000 pregnancies. Ovarian cancer is the second most frequent gynaecological cancer complicating pregnancy except for cervical carcinoma.
Article
Full-text available
To evaluate the correlation of AgNOR count and colposcopy in cases of suspicious cervix. A hundred women presenting in OPD with complaints of postcoital bleeding, discharge per vaginum, pain in the lower abdomen, or intermenstrual bleeding were subjected to colposcopy. After colposcopy, a cervical biopsy was done. Routine paraffin sectioning was do...
Article
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Cervical cytology by Papanicolaou (Pap) smears is an effective means of screening for cervical premalignant and malignant conditions. Cervical intra-epithelial neoplasia (CIN) and cervical cancer remain important health problems for women worldwide. To study the role of Pap smear in detecting premalignant and malignant lesions of cervix; and to det...