Manas Sarkar

Manas Sarkar
Reckitt Benckiser | RB · R&D

PhD

About

35
Publications
7,991
Reads
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271
Citations
Introduction
Senior Research Scientist (Advance Technology and Innovation) in Godrej (GCPL-R&D) Former General Manager (Technology), EntoGenex Industries Sdn Bhd, KL, Malaysia Former Deputy Assistant Director, National Centre for Disease Control (Govt. of India), New Delhi Former Senior Researcher, Defence Research Laboratory (DRDO, Govt. of India), Tezpur (Assam)
Additional affiliations
August 2020 - present
Reckitt Benckiser
Position
  • Science Platform
February 2017 - July 2019
KIIT University
Position
  • Professor (Associate)
April 2014 - present
Godrej Industries
Position
  • Senior Researcher
Education
June 2006 - February 2010
Gauhati University
Field of study
September 1999 - September 2004
University of Burdwan
Field of study

Publications

Publications (35)
Article
The recent advancement in new generation fluorinated pyrethroids (e.g., transfluthrin, metofluthrin etc.), the use of semi-volatile vapour phase insecticides for control of mosquitoes and other domestic pests rises. Enabling the examination of the vapour toxicity profiles of these molecules and many other similar new generation molecules will provi...
Article
Many polymers are known to be used for effective barrier against mass transport of volatile compounds in a number of applications. Barrier properties of macromolecular films towards volatile compounds depend on solubility, permeability, diffusivity, temperature, area and thickness of film, partial vapour pressure of permeating molecules and many ot...
Article
Full-text available
The rate of development and survival of insects depend on many biotic and abiotic factors. One of the factor is availability of nutrient at early developmental stages. We showed that these diets differentially influence the speed of larval development, growth and survival in Culex quinquefasiatus mosquito. Our focus was on soybean powder, commercia...
Article
Intensive exposure to insecticides has resulted in the evolution of insecticide resistance in the mosquitoes. We tested the bio-efficacy of two Culex quinquefasciatus Say (Diptera: Culicidae) laboratory strains differentially bio-responsive to pyrethroids to understand the comparative efficacy of different polyfluorobenzyle and conventional pyrethr...
Article
Full-text available
Despite intensive research on vector-borne diseases, there remains a bias toward bionomics, ento-epidemiology, and operational research. In particular, relatively few studies have focused on vector behaviour and the use of labelling/marking techniques to do so. This manuscript dealt with a unique and easy mass marking technique, done using two diff...
Article
Full-text available
OBJECTIVES: Dengue/Dengue Hemorrhagic Fever (DHF) is the most rapidly spreading vector-borne infection all over the world. Uttarakhand (India) is the prime destination for national and international tourists. Here we assessed the epidemiological characteristics and entomological parameters of dengue/DHF in Uttarakhand (India) using in-depth statist...
Article
Full-text available
Aedes mosquitoes are highly invasive and can survive almost any climatic conditions. They transmit a number of major world's deadly diseases. Therefore, a study was undertaken during December 2010 to evaluate the entomo-epidemiological risk of Aedes mosquito borne diseases (VBD) in Mumbai international seaport areas to minimize potential global hea...
Article
We determined the fatty acid compositions of six species of freshwater microalgae belonging to the Chlorophyta, which were isolated from freshwater bodies in Assam, India. All six microalgae -Desmodesmus sp. DRLMA7, Desmodesmus elegans DRLMA13, Scenedesmus sp. DRLMA5, Scenedesmus sp. DRLMA9 Chlorella sp. DRLMA3 and Chlorococcum macrostigmatum DRLMA...
Article
Full-text available
The Voltage Gated Sodium Channel (VGSC) is critical for binding of different insecticides and plays a key role in insecticide resistance. The insect sodium channel consists of four homologous domains (I to IV), each containing six transmembrane segments (S1 to S6). An important mechanism of resistance to DDT and pyrethroids is termed knockdown resi...
Article
Full-text available
To understand the insecticide resistance status of Culex quinquefasciatus Say (Diptera: Culicidae) (Cx. Quinquefasciatus) to deltamethrin, cyfluthrin, permethrin, lambdacyhalothrin, DDT and malathion in filarial endemic areas of Uttar Pradesh, India. Insecticide susceptibility assays were performed on wild-caught adult female Cx. quinquefasciatus m...
Article
Full-text available
Knockdown resistance (kdr) mutation (L1014F) is a well-defined mechanism of resistance to pyrethroids and DDT in many insect species. Sensitive detection of the mutations associated with resistance is a prerequisite for resistance management strategies. The authors have developed a new real-time molecular diagnostic assay based on SimpleProbe(®)/me...
Conference Paper
Appropriate monitoring of vector resistance to insecticides is an integral component of planning and evaluation of insecticide use in vector borne disease control programmes. Culex quinquefasciatus is the principal vector of bancroftian filariasis in Indian subcontinent. This mosquito has developed resistance to DDT and some pyrethroid insecticides...
Article
Full-text available
The study investigated the development and stage specificity of physiological resistance to insecticides in a colony of Culex quinquefasciatus Say (Diptera: Culicidae) mosquitoes, which are vectors of bancroftian filariasis in India, after selection with deltamethrin. Resistance was selected by exposing the larvae to the concentration of deltamethr...
Article
Full-text available
The insecticide resistance status of Culex quinquefasciatus Say (Diptera: Culicidae) to DDT and deltamethrin across army cantonments and neighbouring villages in northeastern India was investigated. In India, DDT is still the insecticide of choice for public health programmes. In military stations, pyrethroids, especially deltamethrins, are used fo...
Article
Full-text available
To investigate the presence of knock down resistance (kdr) mutation, its frequency distribution in the principal vector of bancroftian filariasis, Culex quinquefasciatus from northeastern India, and to relate kdr genotypes with susceptibility and/or resistance to DDT and deltamethrin in this vectors. Adult female mosquitoes were collected by aspira...
Conference Paper
Voltage Gated Sodium Channel (VGSC) is essential for the initiation and propagation of action potential in the nervous system and other excitable cells. It is also critical for binding of different insecticides and play key role in insecticide resistance. The primary structure of insect sodium channel proteins contains four homologous domains (I –...
Conference Paper
In India, DDT is still the insecticide of choice for public health programmes against vector borne diseases. But recent information on susceptibility status of DDT against mosquitoes in Northeast India is scarce. Continued monitoring of insecticide resistance status, underlying mechanisms and establishment of a data base are of prime importance in...
Conference Paper
Full-text available
Concern over the continued and /or indiscriminate use of insecticides may result in increased resistance that would threaten the sustainability of the vector control strategy. Knock down resistance (kdr) is a well characterized mechanism of resistance to DDT and pyrethroid insecticides in many insects. It is caused by the loss of target site sensit...
Conference Paper
Repeated and indiscriminate use of insecticides especially DDT and introduction of pyrethroid treated bed nets and indoor residual spraying of pyrethroid, mosquitoes develop resistance against these insecticides in various parts of India including Assam. Some of these resistances occur due to target site gene mutation. Sometimes these resistant gen...

Questions

Questions (9)
Question
It was collected in Meghalaya (India) during a rodent-flea association survey last year. See the attached zip folder for the pictures.
Question
Online Survey Invitation: Medical Entomology in India by NCDC, Delhi
Dear Entomologist / Vector Biologist
We are in the process of assessing the present research/surveillance on medical entomology, vector biology and related discipline and trying to collect a nationwide data regarding the current status of available human resources, research / surveillance facilities available in medical entomological research as well as problems faced by the entomologists and future avenues for strengthening this very important field. We are conducting a nationwide online survey on different aspects of entomological research, its prospects, problems, and steps needed to restore this dying discipline to counter the vector-borne diseases in the country. In this process, we need your cooperation and valuable feedback in the form of this online survey. This survey is all about well-being of entomological research and entomologists and for betterment of our scientific, professional, and career interests. This survey will take maximum 10-15 min to complete.
We invite all entomologists (Scientists, Professors, Teachers, Researchers, Students, Technicians, Field Entomologists) having an M.Sc./PhD qualification, who are working (or, had worked) in the field of medical entomology/public health entomology/vector biology & control and allied field in India, to participate in this very important online survey.
To participate please click any one of the link below or copy it into your web browser.
We may request you to share it or forward this survey link to your friends, colleagues, students having above qualification / background and encourage them to participate in this online survey.
Dr. Manas Sarkar
Dr. Kaushal Kumar
National Centre for Disease Control
Centre for Medical Entomology & Vector Management
22-Sham Nath Marg, Delhi-110054
India
Question
SOUTH ASIAN JOURNAL OF EXPERIMENTAL BIOLOGY (ISSN: 2230-9799)
Call for Papers for Special Issue on
"Emerging Trends in Vector Biology Research: merging approaches from basic biology to functional genomics"
Vector biology is the study of arthropod vectors and their role in pathogen transmission. This field encompasses entomology, ecology, microbiology, epidemiology, and molecular genomics and merges approaches ranging from landscape ecology to functional genomics. Arthropod vectors transmit many new and reemerging diseases. Mosquitoes transmit malaria, dengue-dengue hemorrhagic fever, yellow fever, Venezuelan equine encephalitis, and filariasis; sand flies transmit leishmaniasis; ticks transmit Lyme disease and ehrlichiosis; fleas and lice transmit Bartonella; and fleas, lice, and ticks transmit various rickettsioses. Vector borne diseases causes extensive morbidity and mortality and are a major economic burden within disease endemic countries. The emergence and rapid dissemination of arboviruses and their vectors throughout the world, with potentially devastating consequences, is a reality. In the last decade there have been explosive global epidemics caused by dengue, Venezuelan equine encephalitis, Rift Valley fever, Japanese encephalitis, Yellow fever, West Nile, and chikungunya viruses.
Despite remarkable advances in vector biology over the last two decades, vector-borne diseases (VBDs) remain a significant threat to human health worldwide. Control of arthropod vectors is the primary available intervention for some of the most devastating VBDs, particularly those lacking vaccines such as malaria, dengue, trypanosomiasis, filariasis, leishmaniasis, and Chagas disease. Recent advances in empirical, methodological, and theoretical aspects of vector biology are an impetus for reexamining critical research needs aimed at improving human health. The discipline of vector biology is characterized by its emphasis on disease prevention, and successes are well documented. Unfortunately, victories are too often the exception, or when they do occur, they are difficult to sustain. Although vector control remains an essential component in the battle against vector-borne disease (VBD), persistence of vector-borne pathogens and resilience of their arthropod vectors continue to motivate the search for novel solutions.
We invite authors to contribute original research articles as well as few review articles, specially aiming to understand the immunological, molecular and biochemical aspects of insecticide resistance, vector competence, host-vectors-pathogen interaction, interaction between entomopathogenic fungi and insect vectors. We are looking for some novel insight in this field particularly the biology of invasive vectors, priorities in vector biology to improve control of vector-borne disease, integrated approaches in controlling diseases, the role, and mode of action of genes in controlling insecticide resistance phenotypes, recently cloned genes for enhancing virulence of entomopathogenic fungi, and so forth. Potential topics include, but are not limited to:
1. Understanding of the biology of insect vectors of human diseases: entomology, ecology, evolution, molecular biology and functional genomics
2. Experimental vector biology: host-vector-pathogen interaction, insect resistance to pathogens, insect resistance to insecticides, vectorial potentiality
3. Alternative approaches to control insect vector: biological control with conventional and non-conventional approaches
4. In Silico Entomology: identification and characterization of new insecticide targets, novel biomolecules with insecticidal activity and understand the interaction between conventional insecticides and its targets in different insect vectors
5. New insights in insect signaling pathways involved in the activation of defense responses in insect system
6. Integrated vector-borne disease surveillance: vector-borne disease epidemiology & xenomonitoring of insect vectors
7. Reframing priorities and critical needs in vector biology to improve control and management of vector-borne disease
Before submission, authors should carefully read over the journal’s Author Guidelines, which are located at www. http://sajeb.org/about/submissions#authorGuidelines. Prospective authors should submit an electronic copy of their complete manuscript along with a cover letter and name and contact details of three potential reviewers to the Guest Editor by email (manas_sarkar54491@yahoo.com)
Question
I have taken the responsibility of the "Guest Editor" for special issue on "Emerging Trends in Vector Biology Research: Merging approaches from basic biology to functional genomics" in South Asian Journal of Experimental Biology (ISSN: 2230-9799). All prospective authors are most welcome to contact me and submit their manuscript to me. For details go to the following links:
and,
Thanks & Regards
Dr. Manas Sarkar
Question
I have taken the responsibility of the "Guest Editor" for special issue on "Emerging Trends in Vector Biology Research: Merging approaches from basic biology to functional genomics" in South Asian Journal of Experimental Biology (ISSN: 2230-9799). All prospective authors are most welcome to contact me and submit their manuscript to me. For details go to the following links:
and,
Thanks & Regards
Dr. Manas Sarkar
Question
Hi All
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Dear Friends
Hope everything is fine at your end...
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Projects

Projects (3)
Project
Medical Research Council (UK) Confidence in Concept Fund 2015 Tropical Infectious Disease Consortium: Expanding and Accelerating Product Development Collaboration with LSTM and other international institute and Universities. I am the Co-PI of the project.