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Publications
Publications (161)
Background/Objectives: Early diagnosis of autism spectrum disorder (ASD) is a very important factor for improving the quality of life of people on the spectrum, but it still remains a major problem in Europe, especially concerning girls. In this study, we tried to answer the question of what factors affect the age of diagnosis in Poland. Additional...
Background/Objectives: Early diagnosis of ASD a very important factor in improving the quality of life of people on the spectrum, but it still remains a major problem in Europe, especially concerning girls. In this study, we tried to answer the question of what factors affect the age of diagnosis in Poland. Additionally, we tried to establish the t...
Introduction
Bipolar disorder in children is characterized by a different course than in adults, which is a diagnostic difficulty. DAT-1 is a dopamine transporter gene that regulates dopaminergic neurotransmission through the mechanism of active reuptake of this neurotransmitter from the synapse. Polymorphisms within the described gene can result i...
Introduction
In some clinical scenarios obsessive and delusive symptoms exhibit several similarities, making it challenging to differentiate between schizophrenia spectrum disorder (SSD) and obsessive-compulsive disorder (OCD). There are numerous reports of patients suffering from those disorders and manifesting both psychotic and obsession-like fe...
Wstęp Klozapina jest jednym z najskuteczniejszych leków przeciwpsychotycznych, ale jej stosowanie jest ograniczone ze względu na ryzyko wystąpienia ciężkich działań niepożądanych, takich jak neutropenia i agranulocytoza. Największe ryzyko wystąpienia tych powikłań występuje na początku leczenia, ale mogą one również pojawić się w późniejszym etapie...
The aim of the study is to investigate the association of alexithymia with Internet addiction and autism spectrum disorders among adolescents and young adults. The links between alexithymia, ASD and other mental disorders are still a largely unexplored topic in psychiatry. An intriguing question is to what extent alexithymia can be a component of t...
Background
The aim of the study was to investigate the level of fear of the COVID-19 pandemic and to detect a possible correlation between the autistic traits and the level of fear and to learn about other factors that may affect the level of fear.
Methods
The study utilised a questionnaire and was conducted online in the period from 16.02.2021 to...
Cel pracy
Określenie obrazu klinicznego zaburzeń afektywnych dwubiegunowych (ZAD) u hospitalizowanych dzieci oraz młodzieży Oddziału Klinicznego Psychiatrii i Psychoterapii Wieku Rozwojowego w Sosnowcu.
Metoda
Przeprowadzono analizę dokumentacji 288 pacjentów z ZAD poniżej 18 roku życia. Zebrano szczegółowe dane kliniczno-demograficzne oraz ocenio...
There are some initial suggestions in the literature that phoenixin, spexin, nesfatin-1 and kisspeptin may play a role in the pathogenesis of affective disorders. Therefore, they may also be cautiously considered as potential diagnostic or predictive biomarkers of BD. This study aimed to evaluate the levels of the aforementioned neuropeptides in th...
ABSTRACT
Objectives:
Clinical effects observed in cases of oxytocin deficiency can also manifest themselves in disorders of mechanisms responsible, for example, for its secretion. For oxytocin, this function is played by – among others – the cluster of differentiation antigen 38 (CD38). Existing literature along with the correlation between protein...
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that affects social interactions, communication, and behavior. Although the predominant genetic predisposition to ASD seems beyond doubt, its exact nature remains unclear. In the context of social cognition disorders and the basis of ASD, the oxytocinergic and vasopresynergic s...
Cel pracy
Efekty kliniczne obserwowane w przypadku niedoboru oksytocyny mogą być również obecne w przypadku zaburzeń w mechanizmach odpowiedzialnych np. za jej sekrecję. W przypadku oksytocyny funkcję tą pełni miedzy innymi antygen różnicowania komórkowego 38 (CD38). Istniejące dane literaturowe jak również związki białka CD38 z sekrecją oksytocyny...
Autism spectrum disorder (ASD) is a heterogeneous group of neurodevelopmental disorders characterized by food selectivity in a significant portion of the population. The nature of this selectivity remains unclear, with hypotheses suggesting associations with sensory disorders or stereotypical and repetitive patterns of activity and interests. This...
Introduction
Although the Covid-19 pandemic ceased in the numbers of the affected patients, especially the ones with severe manifestation of the disease, its influence on health still remains, affecting not only the somatic but also mental wellbeing. This global crisis impacted almost every person, but not equitable – the mental distress consisted...
Introduction
Stress related to high expectations towards students, a large amount of knowledge necessary to assimilate in a brief period of time, and peer pressure are an important factor in the deterioration of the mental state of medical students. As a consequence, it can lead to burnout and even the development of mental disorders such as depres...
Introduction
Autism spectrum disorder is a heterogeneous group of disorders that affects virtually every population, regardless of their ethnic or socioeconomic origin. The pathogenesis of ASD is probably multifactorial, based on interactions between genetic and environmental factors. Their key elements are disorders in the field of social communic...
Introduction
Autism spectrum disorder is a heterogeneous group of disorders that affects virtually every population, regardless of their ethnic or socioeconomic origin. In recent years, the attention of researchers has been drawn to the participation of the oxytocinergic and vasopressinergic systems in the development of autism spectrum disorders....
Introduction
A lot of issues have raised since the beginning of the pandemic and doctors had to learn how to deal with increasing problems of stress and anxiety. The new situation was a great threat to one’s safety and some more vulnerable people could experience a higher level of anxiety. Patients with autistic traits might be more prone to it. It...
Autism spectrum disorders (ASD) is a heterogeneous group of neurodevelopmental disorders characterized by food selectivity in a significant portion of the population. The nature of this selectivity remains unclear, with hypotheses suggesting associations with sensory disorders or stereotypical and repetitive patterns of activity and interests. This...
Autism spectrum disorders (ASD) are a heterogeneous group of disorders affecting virtually every population, regardless of their ethnic or socioeconomic background. Their pathogenesis is multifactorial, based on interactions between genetic and environmental factors. The key symptom of ASD are deficits in social communication, which are the basis o...
Cel pracy
Celem badania była ocena stężeń wybranych neuropeptydów : feniksyny, speksyny oraz kisspeptyny w surowicy krwi żylnej dzieci i młodzieży z choroba afektywną dwubiegunową, a tym samym ich skuteczności predykcyjnej w tym zaburzeniu.
Metoda
Materiał i metoda. Badanie objęło 75 osób w wieku średnio 15,26 lat (95%CI: 14.86-15.67 ), z czego gr...
Wczesne zachorowanie na schizofrenię (przed 18 r.ż.) jest związane z wyższym niż w przypadku osób dorosłych ryzkiem opóźnionej lub niewłaściwej diagnozy, cięższym przebiegiem choroby, zwiększoną wrażliwością na działania niepożądane leków przeciwpsychotycznych. Celem pracy jest przedstawienie zaleceń na temat postępowania diagnostycznego i terapeut...
Individuals with autism spectrum disorder (ASD) struggle to access high-quality health care due to the shortage of trained providers. ECHO (Extension for Community Healthcare Outcomes) Autism is a unique educational program that allows ASD experts to provide knowledge and skills to professionals in local communities to deliver evidence-based care t...
Cel badań: Określenie związku między chorobą afektywną dwubiegunową (ChAD) u dzieci i młodzieży a zespołem nadpobudliwości psychoruchowej z deficytem uwagi (ADHD) poprzez wybranie najbardziej prawdopodobnej hipotezy tłumaczącej naturę powiązań między tymi dwoma rozpoznaniami na podstawie przeglądu systematycznego literatury. Metoda: Dokonano przegl...
Background: Eating disorders (ED) are a diagnostic category that includes several nosological units such as anorexia nervosa (AN), bulimia nervosa (BN), or binge eating disorder (BED). This category most often concerns women, while the peak incidence falls on the reproductive age. Therefore the issue of ED during pregnancy is an interesting topic....
Aripiprazole, cariprazine and brexpiprazole are antipsychotic drugs (APD) whose action is associated with partial agonism at the dopamine D2/D3 receptors. They are increasingly more widely used in clinical practice, also off-label. The aim of this article is to present the current state of knowledge on the use of these drugs in the treatment of men...
D2/D3 dopamine receptor partial agonists (aripiprazole, brexpiprazole, cariprazine) are increasingly often used in the treatment of mental disorders due to a more favourable tolerability profile as compared to other antipsychotics. The article presents the position statement on the use of these drugs in the treatment of special populations: people...
Zdaniem ekspertów Medycznej Racji Stanu, epidemia COVID-19 wpłynie na zwiększenie zachorowalności na choroby metaboliczne. Dlatego konieczne jest wprowadzenie podatku od cukru oraz edukacji od najmłodszych lat, pełne wykorzystanie możliwości telemedycyny – w tym teleporad i systemów monitorowania glikemii, poszerzenie wskazań refundacyjnych flozyn...
Introduction
One of the defining features of autism spectrum disorder (ASD) are deficits in social interaction and communication. Although their etiology is poorly understood, several lines of evidence from studies on humans and rodents suggest that two nonapeptides – oxytocin and vasopressin – might play a pivotal role in their development.
Objec...
Debata ekspercko- systemowa odnosząca się do nowych możliwości terapeutycznych oraz poprawy modelu opieki w chorobach mózgu. An expert and systemic debate relating to new therapeutic possibilities and improvement of the model of care in brain diseases. ISBN: 978-83-961477-1-4 https://medycznaracjastanu.pl/wp-content/uploads/2021/07/RAPORT_CHOROBY_M...
The aim of the study was to define orthorexia nervosa (ON) based on the latest scientific findings regarding incidence, groups and risk factors as well as relationships between ON and other clinical entities. The paper is based on the review of the MEDLINE/PubMed databases. Publications published between 2009 and 2019 were analyzed in terms of epid...
Cel
Celem prezentowanego badania była identyfikacja i podsumowanie badań analizujących związek pomiędzy stężeniem witaminy D a ryzykiem i nasileniem objawów depresji, opublikowanych pomiędzy styczniem 2008 a styczniem 2019 r.
Materiał i metody
Przeprowadzono systematyczny przegląd literatury opublikowanej w okresie ostatnich 10 lat i dostępnej w r...
Dane dotyczące liczby dzieci i młodzieży wykazującej zaburzenia psychiczne, w stopniu wymagającym pomocy profesjonalnej, są zbliżone w wielu krajach i dotyczą około 10% tej populacji. W Polsce odsetek ten wynosi co najmniej 9%, co oznacza, że pomocy systemu lecznictwa psychiatrycznego i psychologicznego wymaga około 630 000 dzieci i młodzieży poniż...
The vast majority of new neuropeptides feature unique biochemical properties as well as awide spectrum of physiological activity applied in numerous neuronal pathways, including hypothalamus and the limbic system. Special interest should be paid to nesfatin-1 - the relatively recently discovered and still intensively studied regulatory factor and a...
Co-occurring psychiatric conditions are extremely common among people who have autism spectrum disorder (ASD). The Oxford Handbook of Autism and Co-Occurring Psychiatric Conditions presents a compilation of the latest research in this area, summarized by internationally renowned experts. Each chapter presents an overview of the problem or disorder...
MDMA (3,4-methylenedioxymethamphetamine) is a psychoactive substance classified as a hallucinogen. MDMA acts in the brain through a variety of neurochemical mechanisms, reducing anxiety, giving a sense of oneness with other people, expanding empathy, sharpening the senses and intensifying the experience of emotions. Therefore, the use of the MDMA a...
Objectives
It is hypothesized that novel neuropeptides such as phoenixin (PNX), spexin (SPX), and kisspeptin (KISS) are involved in the pathogenesis of eating disorders. The study presented here analyzed neuropeptide concentrations during the course of anorexia nervosa (AN) and aimed to correlate those values with anthropometric and psychometric me...
Introduction
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social interactions, communication, and the presence of stereotyped, repetitive behaviors. Oxytocin (OXT) and arginine-vasopressin are neuropeptides produced in hypothalamus and they are related to processing emotions and social behavior. In th...
Background:
The attitudes of schizophrenic patients toward medications directly impact the treatment compliance. Although noncompliance represents a serious concern in long-term schizophrenia treatment, a detailed information on the factors that impair compliance is still limited. The present study aims to assess the factors related to noncomplian...
Background:
Emotional intelligence (EI) is described as the capacity to be aware of, control, and express one's emotions, and to handle interpersonal relationships judiciously and empathetically. It is considered as one of the most important predictors of success, quality of relationships, and overall happiness. Dynamically changing environment of...
Aim: The aim of the study was to define the patterns of attachment in adults with foetal alcohol syndrome from foster, adoptive and biological families. It was assumed that adults with foetal alcohol syndrome develop insecure attachment styles to a greater extent compared to the general population. Material and methods: Two groups of 30 people part...
Introduction: Autism spectrum disorder (ASD) is found in virtually all population groups regardless of ethnic or socioeconomic backgrounds. Among others, dominant symptoms of autism persistent throughout its course of development include, inter alia, qualitative disorders of social communication and social interactions. Numerous studies have been p...
The aetiology of eating disorders is complex and remains unclear. It has been postulated that centrally and peripherally synthesized proteins, which are responsible for regulation of food intake contributing to homeostatic control of feeding, are involved. While it is unclear whether alternations in these proteins are primary or secondary dysfuncti...
Anorexia nervosa is a disorder characterised by the significant reduction of body mass, usually with other coexisting psychiatric disorders. Psychotic symptoms may develop in its course and, furthermore, there are studies suggesting that sometimes anorexia may be a prodrome for psychosis. In this article, a case study is presented of the patient wi...
Girls and women with autism are often undiagnosed, misdiagnosed or receive a diagnosis
of autism at later age. This can result in adverse outcomes in their well-being, mental health, education, employment, and independence. The diagnosis of autism spectrum condition/disorder (hereinafter referred to as autism), with its current features linked with...
Wywiad do diagnozowania autyzmu ADI-R (Autism Diagnostic Interview – Revised, ADI-R) oraz protokół obserwacji do
diagnozowania zaburzeń ze spektrum autyzmu ADOS-2 (Autism Diagnostic Observation Schedule, Second Edition) to
rzetelnie zwalidowane i wystandaryzowane narzędzia, od dziesięcioleci szeroko stosowane w praktyce klinicznej i badawczej
na św...
Celem niniejszego artykułu jest zwrócenie uwagi na potrzebę utworzenia środowiskowego leczenia dzieci i młodzieży
(alternatywnego dla leczenia szpitalnego i ambulatoryjnego) oraz zakreślenie obszaru działania psychiatrii środowiskowej.
Ma on też przedstawić praktyczne implikacje związane z roczną realizacją projektu Centrum Zdrowia Psychicznego dla...
The article is about aripiprazole - an atypical antipsychotic that is registered in Poland for the treatment of schizophrenia in individuals aged ≥15 years, and moderate to severe manic episodes in the course of bipolar disorder type I in adolescents aged ≥13 years in the treatment lasting up to 12 weeks. The paper discusses the mechanism of action...
Bipolar disorder (BD) is characterized by pathological changes in mood as well as recurring episodes of mania, hypomania, depression and mixed symptoms. In recent years, the number of BD diagnoses has risen considerably in children and adolescents. Itis believed that anaverage rate of prevalence of bipolar spectrum disorder in the pediatric populat...
Anorexia nervosa is a disorder which, in the absence of treatment or in an unfavourable course, can lead to the death of the patient. Frequently, reduced criticism is the element of the psychopathological picture which can result in lack of consent to the proposed treatment. The Mental Health Act specifies the situations in which the treatment with...
Wstęp: Zaburzenia odżywiania są jednostką kryterialną charakteryzującą się niewystarczającym lub nadmiernym wzorcem
odżywiania czy też lękiem związanym z wyglądem własnego ciała. Jedną z ich postaci jest jadłowstręt psychiczny. Oprócz
objawów psychicznych związanych między innymi z zaburzonym postrzeganiem własnego ciała charakterystyczne jest
wyst...
Dyskusja na temat organizacji opieki medycznej i wsparcia pozamedycznego dla osób z zaburzeniami psychicznymi trwa
od wielu lat. W toku rozmów o godności i prawach pacjenta nie można zapominać, że podstawowym prawem chorego jest
prawo do leczenia. I Kongres Zdrowia Psychicznego, który odbył się 8 maja 2017 roku w Warszawie, został zorganizowany
ze...
Due to the dynamic development of molecular neurobiology and bioinformatic methods several novel brain neuropeptides have been identified and characterized in recent years. Contemporary techniques of selective molecular detection e.g. in situ Real-Time PCR, microdiffusion and some bioinformatics strategies that base on searching for single structur...
Introduction:
Deficits in area of communication, crucial for maintaining proper social bonds, may have a prominent adverse impact on quality of life in patients with schizophrenia. Social exclusion, lack of employment and deterioration of family life, may be consequences of aggravated social competencies, caused by inability to properly exhibit an...
Background: In the literature we can find evidence that immunological processes are involved the alterations of cognition in schizophrenic patients. Another factor, which may have an impact on cognitive domains in this clinical group are hormones. Objective: The objective of this review was to explore studies, in which the role of both immunologica...
"Profilaktyka i leczenie zaburzeń odżywiania – wiedza ekspercka”, powstała jako zwieńczenie realizacji zadania Narodowego Programu Zdrowia w 2017 roku.
Po raz pierwszy w Polsce modele leczenia zaburzeń odżywiania zostały opisane przez ekspertów – kierowników klinik i oddziałów ukierunkowanych na terapię pacjentów z zaburzeniami odżywiania, którzy p...
Background: Limbic encephalitis associated with leucine-rich glioma inactivated 1 (LGI1) antibodies can initially have either neurological or psychiatric manifestation.
Background:
Limbic encephalitis associated with leucine-rich glioma inactivated 1 (LGI1) antibodies can initially have either neurological or psychiatric manifestation.
Subject and methods:
The paper describes a case of a 14-year old girl with LGI1 antibodiesassociated limbic encephalitis with initial symptoms suggesting psychotic disturbance...
Objectives:
The aim of this paper is a quantitative assessment of FASD facial phenotype in the Polish population using the Polish version of the 4-Digit Diagnostic Code.
Methods:
The study covered 2 groups of children: 30 children aged 4-7 and 30 children aged 8-11 with a facial phenotype characteristic for the Fetal Alcohol Syndrome (FAS). The...
Objective:
Orthorexia nervosa (ON) is considered an eating disorder (ED), with an excessive fixation on the consumption of healthy food and an obsession with its biological purity. Since the adolescent period poses a risk for EDs, the aim of this study was to assess the prevalence of ON in a population of Polish urban adolescents and some possible...
Autism spectrum disorders (ASD) are caused by disruptions in early stages of central nervous system development and are usually diagnosed in first years of life. Despite common features such as impairment of socio-communicative development and stereotypical behaviours, ASD are characterised by heterogeneous course and clinical picture. The most imp...
Zaburzenia spektrum autyzmu (ASD) są spowodowane zaburzeniami we wczesnych stadiach rozwoju ośrodkowego układu nerwowego i zwykle są diagnozowane w pierwszych latach życia. Pomimo wspólnych cech, takich jak upośledzenie rozwoju społeczno-komunikacyjnego i stereotypowe zachowania, ASD charakteryzuje się niejednorodnym przebiegiem i obrazem kliniczny...
Substance abuse is common issue in youth and may influence youth's suicide thoughts or actions. It can lead to social isolation, low self-esteem, loss of work or school, estrangement from family and friends – all these may create a core of stresses that may lead to suicidal tendencies.
Analysis addictive factors correlating with occurrence of suici...
Objective
Orthorexia nervosa (ON) is an excessive fixation on the consumption of healthy food and an obsession with its biological purity. The aim of this study was to assess the prevalence of ON in a population of Polish urban adolescents and some possible contributory factors.
Method
Validation and adaptation of the ORTO-15 Questionnaire was mad...
Aim:
The aim of the study was the validation and adaptation of the ORTO-15 Questionnaire in the group of the Polish schoolgirls and schoolboys.
Methods:
The study included 399 participants (15-21 years old), all of them high school students in the city of Sosnowiec. The ORTO-15 is a tool created in Italy by L.M. Donini, comprising of 15 items de...
The aim of the study was to analyze the prevalence of suicidal tendencies among adolescents at the age of 18-20.
Material and Methods: The study was based on authorial questionnaire which has been validated. Questionnaire included 16 questions about suicidal thoughts – frequency and causes, non-suicidal self-injuries, trials of committing suicide....
Purpose: The aim of this study is to assess the dependence between the obsessive-compulsive symptoms, the eating disorders symptoms and orthorexia in adolescents aged 15-19, due to define which of these areas orthorexia is closer to. The study controlled such variables as: age, sex, BMI, school type. Subjects and Methods: The study covered 1899 pup...
In the new classification of American Psychiatric Association – DSM-5 – a category of autistic spectrum disorders (ASD) was introduced, which replaced autistic disorder, As- perger syndrome, childhood disintegrative disorder and pervasive developmental disorder not otherwise specified. ASD are defined by two basic psychopathological dimensions: com...
W nowej klasyfikacji American Psychiatric Association - DSM-5 - wprowadzono kategorię zaburzenia ze spektrum autyzmu (ASD; Autism Spectrum Disorder), która zastąpiła takie kategorie jak zaburzenie autystyczne, Zespół Aspergera, dziecięce zaburzenie dezintegracyjne i całościowe zaburzenie rozwoju. ASD są zdefiniowane przez dwa podstawowe wymiary psy...
Anxiety and depressive disorders are characterized by a number of clinical symptoms like decreased mood, apathy, anhedonia and anxiety. An important element of the clinical picture is also neurocognitive impairment. The most common treatment methods for depression and anxiety are pharmacology, psychotherapy or a combination of both methods. The dat...
Mammalian target of rapamycin (mTor) plays multiple role in central nervous system and is involved in regulation of cell viability, differentiation, transcription, translation, protein degradation, actin cytoskeletal organization and autophagy. Recent experimental and clinical studies reveal that disturbances of mTOR signaling are involved in the p...