Malaichamy Ilanchelian

Malaichamy Ilanchelian
Bharathiar University · Department of Chemistry

Ph.D.

About

64
Publications
12,889
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1,347
Citations
Citations since 2016
51 Research Items
1229 Citations
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200

Publications

Publications (64)
Article
Full-text available
In the present work, halloysite nanotubes modified with gold nanoparticles (AuNPs-HNT) are successfully prepared by wet chemical method for the catalytic degradation of phenothiazine dyes (azure B (AZB) and toluidine blue O (TBO)) and also cleaner reduction of 4-(4-nitrophenyl)morpholine (4NM) in the sodium borohydride (NaBH4) media. The catalyst i...
Article
Great attempts have been noticed on the examination and invention of nano bioconjugates owing to prospective uses in various areas such as biocatalysis, biosensors, bioanalytical science, biofuel cells and protein supported nanodevices. An essential feature of our insightful of bionanoconjugates was to quantitatively distinguish how biomacromolecul...
Article
Herein, we have proposed a new, highly specific and simple colorimetric assay for the chemosensing of sulfide ions (S²⁻) in environmental water samples, by using cysteine-functionalized colloidal silver nanoparticles (Cys-AgNPs). As prepared Cys-AgNPs and their interface with S²⁻ ions were demonstrated using absorption, high resolution transmission...
Article
In the present work, we have synthesized cetyltrimethyl ammonium bromide (CTAB) capped gold nanorods (Au NRs) to evaluate apparent binding affinities for the adsorption of trypsin (TRP). The interaction between TRP and Au NRs is explained elaborately using high resolution transmission electron microscopy (HR-TEM), dynamic light scattering (DLS), su...
Article
The present study elucidates the preparation of colorimetric [email protected] core-shell nanoparticles ([email protected] core-shell NPs) probe for sensitive, label-free and rapid sensing of trace levels of cysteamine (CSH). The [email protected] core-shell NPs were prepared by a simple chemical reduction method. The physico-chemical properties of...
Article
1,5-Bis(4-chlorophenyl)-3-(2-(4-methylpiperazin-1-yl)quinolin-3-yl)pentane-1,5-dione was synthesised and characterised using single-crystal X-ray Crystallography, FT-IR, 1 H-NMR, 13 C-NMR and UV-Visible spectroscopy. DFT calculations were performed at the B3LYP/6-311 ++ G (d.p) level of theory in the gas phase. Frontier Molecular Orbitals (FMO) yie...
Article
In the present work, we proposed a simple, sensitive and selective fluorescent method for the detection of Rutin (Rut) and Quercetin (Que) based on the inner filter effect (IFE) by utilizing water- soluble cysteine stabilized copper nanoclusters (Cys-CuNCs) as a fluorescent probe. The Cys-CuNCs were successfully synthesized and characterized by UV-...
Article
Quinoline appended hemicyanine 6MIM with strong ICT character was successfully synthesized through simple condensation reaction of 6-methoxy-2-chloro-3-formyl quinoline with 2-benzothiazolinium iodide. The photophysical characteristics of synthesized probe revealed that it would selectively detect glutathione (GSH) when it compared with different a...
Article
In this paper, -cyclodextrin (-CD) functionalized gold nanoparticles (-CD AuNPs) based simple, rapid, on-site and naked eye colorimetric sensor for the sensitive detection of cysteine (Cys) were reported. -CD AuNPs nanoprobe was completely characterized with respect to morphology, optical properties and stability. Surface plasmon resonance (SPR...
Article
Spectroscopic and thermodynamic investigation of molecular interactions in a binary mixture of 2′,3′-epoxypropyl-N-methyl-2-oxopyrrolidinium acetate ([EPMpyr][OAC]) ionic liquid (IL) with a bovine serum albumin (BSA) aqueous solution was carried out. The thermophysical properties of density (ρ) and speed of sound (u) were first measured for the bin...
Article
A simple, colorimetric and visual method is described for the determination of cysteamine (CA) using polyvinylpyrrolidone-stabilized silver nanoparticles (PVP-AgNPs) as a colorimetric probe. The sensing method was based on the aggregation of PVP-AgNPs that led to the changes in the color and absorption profile of the probe. The aggregation of PVP-A...
Article
In this paper, we developed a facile, rapid, selective and sensitive colorimetric method for the detection of cyanide ions (CN−) by using gold nanobipyramids (Au NBPs). The structure and morphology of the as prepared Au NBPs are characterized by UV-visible spectroscopy, high-resolution transmission electron microscopy (HR-TEM) and zeta potential me...
Article
This study explores the adsorption and binding interaction of bovine hemoglobin (BHb) and lysozyme (Lys) with gold/silver alloy nanoparticles (Au/Ag alloy NPs) using various spectroscopic approaches. The fluorescence behaviour of tryptophan residues of the proteins after Au/Ag alloy NPs addition revealed that the static quenching interactions. The...
Article
Unique characteristics displayed by phytoconstituent conjugated nanoparticles and their crucial interactions with proteins serve to develop nanoparticle-bio-interface platform. Gold nanoparticles of 16 nm in size were generated using aqueous extracts of pine bark and further conjugated to human serum albumin. The gold nanoparticles-protein complex...
Article
Full-text available
The detailed investigation of methylene blue (MB) dye with ovalbumin (OVA) was examined by multispectroscopic and computational techniques. The experimental results of emission spectral studies displayed that the quenching behaviour of OVA with MB dye is due to static quenching mechanism. Isothermal titration calorimetry experimental results sugges...
Article
A novel class of unexpected 1,10-phenanthrolinederivatives were synthesized from 2,3-dihydroacridin-4(1H)-ones with 3-aminonaphthalen-2-carboxylic acid in presence of phosphorus oxychloride at 130°C and simple perceptive emission intensity increasing assay was developed effectively to detect the very low concentrations of Zn2+ and Cd2+ ions. Emissi...
Article
Abstract We have constructed a new coumarin based fluorescence probe BENZPYR with ICT character through condensation of N, N-diethylamino-3-acetyl coumarin with 2-hydrazinobenzothiazole. The absorbance and fluorescence spectral characteristics of BENZPYR revealed that the chemosensor can specifically detect for Cu2+ ions over other different metal...
Article
Full-text available
ABSTRACT: 3-(7-(Diethylamino)-2-oxo-2H-chromen-3-yl)-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5(4H)-one (COPYR)was competently synthesized from methyl 3-(7-(diethylami-no)-2-oxo-2H-chromen-3-yl)-3-oxopropanoate and 2-hydrazi-no-4-phenyl thiazole. The interactions of receptor COPYRwith various ions were investigated through absorption andsteady-statefluo...
Article
Full-text available
In this paper, we illustrate an efficient, convenient, and simplistic fluorescence technique for the specific identification for nitro explosive 2,4,6-trinitrophenol (TNP) in 100% water medium by bright cyan blue color-emitting poly(vinylpyrrolidone)-supported copper nanoclusters (PVP-CuNCs) as a fluorescence probe. PVP-CuNCs exhibited linear fluor...
Article
In recent work, we demonstrate a rapid colorimetric and easy visual determination of cyanide ions (CNˉ ions) in water based on gold nanoparticles stabilized with β-cyclodextrin (β-CD). Optical detection of CNˉ ions were carried out using β-CD-AuNPs by tracking the changes in the SPR band and colorimetric nature of the β-CD AuNPs. This colorimetric...
Article
The intensity of research, probing the interactions between proteins and ionic liquid (IL), has been increasing and parallels the fast-growing applications of ILs in biotechnology. The specific aspects which have attracted the involvement of researchers are stabilization, separation, biochemical and enzymatic reactions of proteins. In this work the...
Article
Full-text available
Herein, we describe a bright-red-emitting ovalbumin-protected gold nanoclusters (OVA-AuNCs) that were prepared and applied as a luminescent probe for a simple, rapid, and highly sensitive determination of cyanide ions (CN⁻ ions) based on an emission quenching and colorimetric method. Initially, an intense red-emissive fluorescence of the OVA-AuNCs...
Article
On the premise that bovine serum albumin (BSA) is a suitable substitute for Human Serum Albumin (HSA) in experiments, its interactions with ionic liquid (IL), N‑2′,3′‑epoxypropyl‑N‑methyl‑2‑oxopyrrolidinium chloride, ([EPMPyr]{Cl}), was studied. This was done on the basis that the data would give information on the potential role of ionic liquids (...
Article
Full-text available
In the present work, we have developed a label free, colorimetric and non aggregation based gold nanoparticle (Au NPs)/Ascorbic acid (AA) probe without employing any aggregation agents for detection of trace amounts of silver ions (Ag⁺ ions) in aqueous solution and water samples. This detection probe can be prepared by simply mixing Au NPs with AA....
Article
A simple fluorescent bioassay for on time, ultrasensitive and highly selective determination of creatinine is massive impact in clinical science. Herein, we describe red emittive bovine serum albumin modified copper nanoclusters (BSA-CuNCs) are applied as precise fluorescent nanoprobe for the optical recognition of creatinine. Fluorescent features...
Article
Herein, we report the highly sensitive and selective determination of vitamin B12 (VB12) using histidine-stabilized copper nanoclusters (His-CuNCs) as a fluorescent probe by the spectrofluorometry method. The as-synthesized His-CuNCs were characterized by UV–Vis absorption, steady-state emission, and high-resolution transmission electron microscopy...
Article
A simple, visual naked eye colorimetric sensor for rapid, sensitive and selective determination of cysteine (Cys) was potential impact in biological and environmental sciences. Herein, we report a sensitive and highly selective sensing of Cys amino acid over other natural amino acids using β-cyclodextrin functionalised silver nanoparticles (β-CD Ag...
Article
In the present study, indepth characterization of binding aspects of Azure A (AZA) and Azure B (AZB) with transfer Ribonucleic acid (t-RNA) from Escherichia coli (E.coli) is investigated using spectroscopic techniques. The absorbance and fluorescence properties of these dyes have been remarkably changed upon binding with t-RNA. Significant changes...
Article
Herein, determination of dangerous mercury cation (Hg²⁺) and sulfide anion (S²⁻) using β-cyclodextrin functionalised silver nanoparticles (β-CD AgNPs) based on both naked eye visual approach and optical spectrophotometry were expressed. The β-CD AgNPs were prepared by wet chemical method and it exhibits surface plasmon resonance (SPR) band at 400 n...
Article
Full-text available
This paper describe an ultrasensitive and highly selective dopamine (DA) assay that is making use of glutathione protected silver nanoclusters (GSH-AgNCs) acting as a nanoprobe. The GSH-AgNCs exhibit red fluorescence (with excitation/emission peaks at 490/645 nm) which increases on addition of DA, probably due to the hydrogen bonding interaction of...
Article
In this contribution, we have described the cost effective, simple, selective and sensitive approach for the detection of hypochlorite (ClO-) using gold/silver alloy nanoparticles (Au/Ag alloy NPs) as a colorimetric probe. The synthesized Au/Ag alloy NPs was characterized by UV-Vis absorption, Zeta potential and high resolution transmission electro...
Article
Full-text available
An efficient and environmentally benign one-pot multicomponent synthesis of E-chalcones was developed using a mild and reusable new boron nitride-sulphonic acid catalyst. The catalyst was prepared by activating the boron nitride surface with nitric acid, followed by a simple reaction with 3-mercaptopropyl trimethoxysilane. The catalyst was characte...
Article
A series of novel dispiro piperazinyl-quinolinyl-thioxothiazolidin-2, 4-dione derivatives were synthesized and characterised by FT-IR ¹H, ¹³C, 2D NMR and HRMS spectroscopic techniques. A representative compound 1'-(2-(4-methylpiperazin-1-yl)quinolin-3-yl)-2″-thioxo-5′,6′,7′,7a'-tetrahydro-1′H,2H-dispiro[acenaphthylene-1,3′-pyrrolizine-2′,5″-thiazol...
Article
In the current research, the surface of gold nanopsarticles (AuNPs) modified using folic acid (FA) as a capping agent for improving their photophysical properties with thionine (TH). The binding nature of TH with folic acid stabilized gold nanoparticles (FA-AuNPs) are characterized using absorption, emission, Fourier Transform Infrared Spectroscopy...
Article
Full-text available
In the present study, we have synthesized glutathione modified silver nanoparticles (GSH-AgNPs) in aqueous medium and are characterized by absorption, high resolution transmission electron microscope (HR-TEM), selective area electron diffraction (SAED) pattern, dynamic light scattering (DLS), Zeta potential and Fourier transform infrared (FT-IR) sp...
Article
Full-text available
Herein, we report a green preparative strategy for the synthesis of crystalline silver nanoparticles (Ag NPs) using Ficus amplissima leaf extract (FA-LE) in aqueous medium under ambient sunlight irradiation. The prepared FA-LE capped Ag NPs are characterized using absorption spectroscopy, high resolution transmission electron microscopy (HR-TEM), F...
Article
In this work, we have developed a simple, rapid, sensitive and selective colorimetric method for the quantitative determination of hypochlorite (ClO−) ion by using triangular silver nanoprisms (AgNPRs) as a colorimetric probe. The synthesized AgNPRs were characterized by UV-visible absorption and high resolution transmission electron microscopy (HR...
Article
The nature of binding mechanism of toluidine blue O (TBO) with chicken egg white lysozyme was studied comprehensively by various spectroscopic and computational methods. Both steady state and time resolved fluorescence studies unambiguously point to the prevalence of static quenching mechanism in lysozyme-TBO system. Thermodynamic parameters reveal...
Article
We report a simple visual colorimetric method for the highly sensitive and selective detection of thiamine (Vitamin B1) by silver nanoparticles (AgNPs) as a probe. AgNPs surface was modified by glutathione (GSH) and their morphology, size distribution and optical properties were characterized by high resolution transmission electron microscope (HR-...
Article
The studies on protein-dye interactions are important in biological process and it is regarded as vital step in rational drug design. The interaction of thionine (TH) with human serum albumin (HSA) was analyzed using isothermal titration calorimetry (ITC), spectroscopic and molecular docking technique. The emission spectral titration of HSA with TH...
Article
Full-text available
The article describes a simple method for the rapid photometric and visual detection of sulfide in water samples. Silver nanoparticles were capped with chitosan (chit-AgNPs) and then characterized by absorption spectroscopy, high resolution transmission electron microscopy and zeta potential measurements. Chit-AgNPs exhibit a strong surface plasmon...
Article
New [RuCl2(1,5cod)(L1)] (1), [RuCl2(1,5cod)(L2)] (2), [RuCl2(1,5cod)(L3)] (3), [RuCl2(1,5cod)(L4)] (4), [RuCl2(1,5cod)(L5)] (5) (L = (p-R-N-(pyridin-2-ylmethylene)aniline), R = H (L1), Cl (L2), OCH3 (L3), CH3 (L4), L5 = (9-ethyl-N-(pyridin-2-ylmethylene)9H-carbazole-3-amine and 1,5cod = η4-cyclooctadiene) complexes were synthesized and characterize...
Article
In this contribution, we have developed a simple, environmentally friendly fluorescent turn-off sensor for the detection of copper (Cu2+) ions in aqueous solution by using lysozyme stabilized gold nanoclusters (Lys-AuNCs) as a fluorescent probe. Since lysozyme acted as both a reducing and stabilizing agent, the use of other external reducing or sta...
Article
In the present investigation, we have systematically studied the binding mechanism of model protein human serum albumin (HSA) with Gold/Silver alloy nanoparticles (Au/Ag NPs) using multi spectroscopic techniques. Absorption spectral studies of Au/Ag NPs in the presence of increasing concentrations of HSA resulted in slight red shift of Au/Ag NPs su...
Article
Full-text available
Toluidine blue O (TBO) is a cationic photosensitizer belongs to the class of phenothiazinium dyes. It has been widely used in photodynamic therapy due to its preferential affinity towards cancer cells in vivo. The present study, reports a detailed binding mechanism of the photodynamic therapeutic agent TBO with bovine hemoglobin (BHb) using steady...
Article
This study explores the binding interaction of thionine (TH) with bovine serum albumin (BSA) under physiological conditions (pH 7.40) using absorption, emission, synchronous emission, circular dichroism (CD) and three-dimensional (3D) emission spectral studies. The results of emission titration experiments revealed that TH strongly quenches the int...
Article
In the present work, we have carried out a detailed investigation on the binding interaction of acridine orange (AO) with borate capped gold nanoparticles (Au NPs) by absorption spectroscopy, steady state emission spectroscopy, time resolved fluorescence spectroscopy, high resolution transmission electron microscopy (HR- TEM), dynamic light scatter...
Article
In the present study the interaction of chemotherapeutic agent, Azure A (AZA) with Human serum albumin (HSA) and Bovine serum albumin (BSA) was investigated by multi spectroscopic and molecular docking methods. The influence of inner filter effect (IFE) on the emission quenching of HSA/BSA at low concentration of AZA (absorption value < 0.1) sugges...
Article
In the present investigation the interaction of a biologically active photodynamic therapeutic agent Toluidine blue O (TBO) with Serum albumins viz Human serum albumin (HSA) and Bovine serum albumin (BSA) was studied using absorption, emission, circular dichroism spectroscopy and molecular docking experiments. The emission titration experiments bet...
Article
Full-text available
In the present investigation, we have elucidated the interaction between thionine (TH) and bovine hemoglobin (BHb) under physiological conditions by using absorption, emission, time resolved fluorescence, synchronous fluorescence, circular dichroism (CD) and three dimensional emission (3D) spectral studies. Molecular docking experiment was also car...
Article
The interaction(s) of Toluidine Blue O (TBO) with DNA was investigated using absorption and emission spectral methods. The binding of TBO with DNA was understood from the observed hypochromism in the absorption spectra and decrease in the emission intensity of TBO. From the absorption and emission spectral data, two binding constants were estimated...
Article
In the present investigation the absorption and emission spectral studies of toluidine blue O with SDS to understand the formation of photoactive monomer dyes and photoactive dimmer dyes were carried out. Like many organic dyes the optical properties of TBO changes in the presence of surfactant and due to the formation of ion associates and a micel...
Article
The interaction of thioflavin T, 3,6-dimethyl-2-(4-dimethylaminophenyl)-benzothiazolium cation (TFT) with DNA is studied using absorption and emission spectral methods. The observed hypochromism in the absorption spectra suggests that the TFT binds with DNA. The emission spectral changes show two different emission bands at 450 and 485nm for TFT in...
Article
The metal phthalocyanines (MPCs)-adsorbed Nafion (Nf) membranes (Nf/MPCs) are prepared and used for the photocatalytic reduction of nitrite ion. The selective formation of NH4OH is observed when the Nf/MPC membrane is dipped in nitrite ion solution and photolysed in the presence of sacrificial electron donor such as triethanolamine (TEA). The Nf/MP...
Article
Full-text available
The absorption and emission spectral properties of toluidine blue O (TBO) and Meldola's blue (MDB) in the presence of cyclodextrins (CDs) were studied. Formation of 1 : 1 and 1 : 2 (CD-Dye) inclusion complexes were observed with β-CD and γ-CD, respectively. An increase in the emission intensity was noticed in the presence of β-CD due to the formati...

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