Majd Abdallah

University of Bordeaux · Department of Life and Health Sciences

Inferring reliable brain-behavior associations requires synthesizing evidence from thousands of functional neuroimaging studies through meta-analysis. However, existing meta-analysis tools are limited to investigating simple neuroscience concepts and expressing a restricted range of questions. Here, we expand the scope of neuroimaging meta-analysis...

Deficits in neurocognitive functioning are trait-like vulnerabilities that have been widely studied in persons with substance use disorders (SUD), but their role in the craving–use association and relapse vulnerability remains poorly understood. The main objectives of this study were to examine whether executive capacities moderate the magnitude of...

The lateral prefrontal cortex (LPFC) of humans enables flexible goal-directed behavior. However, its functional organization remains actively debated after decades of research. Moreover, recent efforts aiming to map the LPFC through meta-analysis are limited, either in scope or in the inferred specificity of structure-function associations. These l...

Deficits in cognitive functions are frequent in schizophrenia and are often conceptualized as stable characteristics of this disorder. However, cognitive capacities may fluctuate over the course of a day and it is unknown if such variation may be linked to the dynamic expression of psychotic symptoms. This investigation used Ecological Momentary As...

Involvement of the cerebellum in addiction has been hypothesized to arise from its role in conditioned responses, predicting drug availability and thus provoking craving, i.e. the "strong desire or urge to use the substances" (DSM V, 2013). Recent models of addiction suggest that craving fluctuates over time and that the risk of relapse may be link...

Inferring reliable brain-behavior associations requires synthesizing evidence from thousands of functional neuroimaging studies through meta-analysis. However, existing meta-analysis tools are limited to investigating simple neuroscience concepts and expressing a restricted range of questions. Here, we expand the scope of neuroimaging meta-analysis...

The human lateral prefrontal cortex (LPFC) enables flexible goal-directed behavior. Yet, its organizing principles remain actively debated despite decades of research. Meta-analysis efforts to map the LPFC have either been restricted in scope or suffered from limited expressivity in meta-analysis tools. The latter short-coming hinders the complexit...

Chronic tobacco smoking remains a major health problem worldwide. Numerous smokers wish to quit but most fail, even if they are helped. The possibility of identifying neuro-biomarkers in smokers at high risk of relapse could be of incredible progress toward personalized prevention therapy. Our aim is to provide a scoping review of this research top...

Alcohol use disorder (AUD) is widely associated with cerebellar dysfunction and altered cerebro-cerebellar functional connectivity (FC) that lead to cognitive impairments. Evidence for this association comes from resting-state functional magnetic resonance imaging (rsfMRI) studies that assess time-averaged measures of FC across the duration of a ty...

Studies of resting-state functional connectivity (FC), measured by functional magnetic resonance imaging (rsfMRI), have revealed extensive functional connections between the cerebellum and association regions in the brain, supporting an important role for the cerebellum in cognition. These findings have been based on static FC measures averaged acr...

Human and animal brain studies bring converging evidence on a possible role for the cerebellum and the cerebro-cerebellar system in impulsivity. However, the precise nature of the relation between cerebro-cerebellar coupling and impulsivity is far from understood. Characterizing functional connectivity (FC) patterns between large-scale brain networ...

Converging evidence from human and animal studies predict a possible role of the cerebellum in impulsivity. However, this hypothesis has not been thoroughly investigated within the framework of functional connectivity (FC). To address this issue, we employed resting-state functional magnetic resonance imaging data and two self-reports of impulsivit...

Trait impulsivity is a component of personality that involves a tendency to display behavior with little to no forethought nor consideration of consequences. Impulsivity takes a part in the disease pattern of several neuropsychiatric disorders that exhibit alterations in cortico-cerebellar loops such as addiction and ADHD. We hypothesize that the f...

The 24-hour biological rhythms known as circadian rhythms have been a fast-growing field of research for decades. Recently, the study of circadian rhythms has become important and promising for medical research, especially in the field of cancer treatment. This is due to the fact that perturbations in circadian rhythms have been associated with the...

Schizophrenia exhibits major deficits in Executive functioning which has been related to brain structural and functional impairments. The principal objective of this project is to acquire resting state functional MRI from patients with schizophrenia who are participating in a study of daily life risk factors, and link brain functional connectivity...