Maira Libertad Soligo Takemoto

• RN, MSc, PhD
• PostDoc Position at São Paulo State University

Resumo: O Estudo da Mortalidade Materna conduz uma investigação hospitalar dos óbitos maternos ocorridos em 2020/2021 nas maternidades amostradas na pesquisa Nascer no Brasil II, com os seguintes objetivos: estimar o sub-registro da mortalidade materna e calcular um fator de correção e a razão de mortalidade materna (RMM) corrigida; validar as caus...

The Maternal Mortality Study conducts a hospital investigation of maternal deaths that occurred in 2020/2021 in the maternity hospitals sampled by the Birth in Brazil II survey, with the following objectives: estimate the maternal mortality underreporting; calculate a correction factor and the corrected (MMR); validate the causes of maternal mortal...

Brazil has made advances in obstetric care in public and private hospitals; however, weaknesses in this system still require attention. The Brazilian Ministry of Health, aware of this need, funded the second version of the Birth in Brazil survey. This study aimed to evaluate: prenatal, labor and birth, postpartum, and abortion care, comparing the r...

Background The study aims to assess agreement between data obtained from interviews with postpartum women and their health records about labor and birth characteristics, newborn care, and reasons for cesarean birth. Methods The present study analyzes the Birth in Brazil study dataset, a nationwide hospital‐based survey that included 23,894 postpar...

Background: In 2015, a quality improvement (QI) intervention to reduce cesarean sections (CS)-the Adequate Childbirth Project (PPA)-was implemented in the private sector in Brazil. This analysis aims to compare safety care measures and adverse outcomes between women exposed to the PPA intervention to those receiving standard care. Methods: The a...

Background Ex-vivo myography enables the assessment of muscle electrical activity response. This study explored the viability of determining the physiological responses in muscles without tendon, as rectus abdominis muscle (RAM), through ex-vivo myography to assess its potential as a diagnostic tool. Results All tested RAM samples (five different...

Collaborative models (CM) focused on intrapartum care shared between both midwives and obstetricians have been proposed as a strategy to reduce these rates. Our aim was to compare use of evidence-based practices, obstetric interventions and c-section rates in two settings: a maternity hospital that applies a CM of care (MRJ) and data from a pool of...

Introduction and hypothesis: To investigate relaxin-2 concentration comparing gestational diabetes mellitus (GDM) and non-GDM patients during pregnancy according to urinary incontinence (UI) and pelvic function status. Methods: This is a cross-sectional study evaluating 282 pregnant women from 24 weeks of gestation. The participants were divided...

Gestational diabetes mellitus (GDM) plus rectus abdominis muscle (RAM) myopathy predicts long-term urinary incontinence (UI). Atrophic and stiff RAM are characteristics of diabetes-induced myopathy (DiM) in pregnant rats. This study aimed to determine whether swimming exercise (SE) has a therapeutic effect in mild hyperglycemic pregnant rats model....

Abstract: Objectives: To provide an overview of deaths due to COVID19 Acute Respiratory Distress Syndrome (ARDS) among obstetric patients in Brazil, until March 2021,using surveillance system (SS) data. Methods: By March 8, 2021, we identified fatal cases of COVID19 in pregnant and postpartum women reported to the Brazilian Ministry of Health's ARD...

In several countries, midwives and/or obstetric nurses provide primary care for pregnant women. In the Supplementary Health System in Brazil, coverage of antenatal care is mandatory, and carried out by obstetricians. The objective of this study is to conduct a cost-effectiveness analysis, comparing clinical outcomes and costs associated with the in...

Objective To compare risk of death due to COVID‐19 among pregnant, postpartum, and non‐pregnant women of reproductive age in Brazil, using the severe acute respiratory syndrome surveillance system (SARS‐SS). Methods A secondary analysis was performed of the Brazilian official SARS‐SS, with data retrieved up to August 17, 2020. Cases were stratifie...

Ensuring women’s need for sexual and reproductive healthcare are met should be a priority during disease outbreaks, say Maira L S Takemoto and colleagues

Background: In Brazil, a 20% increase in maternal mortality rate due to COVID-19 is projected for 2020. On January 4, 2021, the P.1 SARS-CoV-2 genetic variant was firstly identified in the country and recent data has indicated an association with higher hospitalization rates and mortality. The impact of P.1 variant in the obstetric population remai...

Synopsis During the study period, 523 pregnant or postpartum women died in Brazil due to confirmed COVID‐19 or undetermined etiology. This results in a projected COVID‐19 MMR of 17.5/100 000 or potentially even higher.

BACKGROUND: Lubiprostone is a type 2 chloride channel activator that has been shown to be efficacious and safe in the treatment for chronic constipation. OBJECTIVE: To systematically review randomized clinical trials (RCTs) assessing efficacy of lubiprostone for patients with chronic idiopathic constipation (CIC), irritable bowel syndrome with pre...

Objective To evaluate whether clinical and social risk factors are associated with negative outcomes for COVID‐19 disease among Brazilian pregnant and postpartum women. Methods A secondary analysis was conducted of the official Acute Respiratory Syndrome Surveillance System database. Pregnant and postpartum women diagnosed with COVID‐19 ARDS until...

This is a letter commenting a systematic review about maternal and perinatal mortality and vertical transmission associated with COVID-19

Objective: To describe clinical characteristics of pregnant and postpartum women with severe COVID-19 in Brazil and to examine risk factors for mortality DESIGN: Cross-sectional study based on secondary surveillance database analysis SETTING: Nationwide Brazil POPULATION OR SAMPLE: 978 Brazilian pregnant and postpartum women notified as COVID-19 A...

Rev Bras Ginecol Obstet 2020;42(8):445-447.

160 maternal deaths due to COVID‐19 have been reported worldwide, most of them in middle‐income countries, representing a barrier to reducing maternal mortality.

At the time of writing 124 pregnant or postpartum women in Brazil have died due to COVID‐19 (representing a mortality rate of 12.7%), a figure that currently surpasses the total number of COVID‐19‐related maternal deaths reported throughout the rest of the world.

We examined the Brazilian Acute Respiratory Distress Syndrome Surveillance System searching from COVID-19 ARDS cases among pregnant women with complete data on ethnicity until July 14, 2020. Black women had similar mean age and morbidity profile as compared to White women, but were hospitalized in worse conditions, had a higher rate of ICU admissio...

Dear Editor, Tai and collaborators raised important questions about the potential biomedical factors and social determinants that play a role in the observed racial disparities on COVID-19 outcomes in the US[1]. Evidence of such disproportionate impact is also arising on historically oppressed ethnic groups in Brazil, current worldwide pandemic epi...

Sir, We carefully read the work by Mendoza et al.,1 a prospective observational study including 42 women, eight with severe and 34 with non‐severe coronavirus disease 2019 (COVID‐19) pneumonia. Six women presented signs and symptoms of pre‐eclampsia and were assessed with uterine artery pulsatility index (UtAPI) and angiogenic factors (soluble fms...

Method: presentation of 3 low-cost simulators designing, based on educational needs identified in real-world training contexts. The developing process is presented in detail and each simulator was tested and re-tested, being submitted to improvements until their final version. The simulators presented are: delivery simulator shorts, Neoprene uterus...

ABSTRACT BACKGROUND: Adequate fiber intake is associated with digestive health and reduced risk of several noncommunicable diseases and is recognized as essential for human health (World Health Organization, 2003). The World Health Organization (WHO) recommends a daily fiber consumption of ≥25 g, but previous studies observed a fiber intake in Br...

Objective To obtain cesarean-section (CS) rates according to the Robson Group Classification in five different regions of Brazil. Methods A descriptive epidemiological study using data from secondary birth records from the Computer Science Department of the Brazilian Unified Health System (Datasus, in Portuguese) between January 1st, 2014, and Dece...

Objective The aim of this study was to collect and analyze data from different sources to have a general overview of COVID-19-related maternal deaths in Brazil, as well as to compare data with worldwide reports. Study design We systematically searched data about COVID-19 maternal deaths from the Brazilian Ministry of Health surveillance system, St...

Background: Pelvic floor muscles (PFM) and rectus abdominis muscles (RAM) of pregnant diabetic rats exhibit atrophy, co-localization of fast and slow fibers and an increased collagen type I/III ratio. However, the role of similar PFM or RAM hyperglycemic-related myopathy in women with gestational diabetes mellitus (GDM) remains poorly investigated...

Our aim was to systematically review data about the risk of sexually transmitted infections (STI) and bacterial vaginosis among lesbian women and to suggest strategies to improve prevention, diagnosis and treatment. A search strategy for lesbian, STI and bacterial vaginosis was applied to PubMed, LILACS and BDENF databases. Of 387 unique references...

Received: September 21, 2017 Accepted: February 12, 2018 Published online: June 01, 2018 Issue release date: July 2018

Backround: Cesarean rates in Brazil have reached over 50 percent of all births. Multiple factors have been studied aiming to explain these rates. Mode of delivery preferences among university students may provide insights into strategies to reduce those numbers. Methods: A cross-sectional study was conducted enrolling students who attended Healt...

Background Multiple sclerosis (MS) is a central nervous system disease associated with irreversible progression of disability, which imposes a substantial socioeconomic onus. The objective of this study was to determine the economic impact of multiple sclerosis from the Brazilian household and healthcare system perspectives. Secondary objectives we...

Objective To compare therapy for prophylaxis of venous thromboembolism and costs related to hospitalization of patients undergoing total knee and hip replacement within the context of the Brazilian health system. Methods A retrospective study of patients undergoing arthroplasty in 2010 in a public hospital and two private hospitals in the state of...

Multiple sclerosis (MS) is a chronic disease associated with several impacts; especially regarding patients' health-related quality of life (HRQL). EuroQol 5 Dimensions questionnaire (EQ-5D) provides self-reported analysis of HRQL and utility scores. Although the British algorithm to convert EQ-5D responses into utility is the most used in the lite...

REVISÃO Resumo Distocia de ombro é um evento imprevisível e proossionais habilitados para assistir ao parto devem estar capacitados para diagnosticar e instituir manobras efetivas para sua resolução. Tais manobras têm por objetivo aumentar a pelve funcional, reduzir o diâmetro biacromial e melhorar a relação feto-pélvica, facilitando o desprendimen...

To compare costs and clinical benefits of three additional therapies to metformin (MF) for patients with diabetes mellitus type 2 (DM2). A discrete event simulation model was built to estimate the cost-utility ratio (cost per quality-adjusted life years [QALY]) of saxagliptine as an additional therapy to MF when compared to rosiglitazone or pioglit...

Regarding biological drugs approved for psoriasis in Argentina, etanercept effectiveness is not lost in retreatment regimens, which allows continuous or paused therapeutic schemes. This study aims to perform cost-effectiveness and cost-utility analyses of biologic alternatives for moderate to severe psoriasis in Argentina, from a public payer's per...

Biologic treatment in psoriasis is indicated for obtaining clinical response after systemic drugs fail. Among those approved in Colombia, etanercept effectiveness is not lost in retreatment regimens, which allows continuous or paused therapeutic schemes. This study aims to perform cost-effectiveness and cost-utility analysis of biologic alternative...

Biologic treatment after systemic drugs fail in psoriasis is indicated for obtaining clinical response. Etanercept effectiveness is not lost in retreatment regimens, which allows continuous or paused therapeutic schemes. The inclusion of etanercept in the private health care system practice represents a breakthrough to psoriasis treatment in Brazil...

To estimate the prevalence of constipation concomitant to opioid treatment and related resource use and costs from the private payer perspective. In this retrospective database analysis, patients receiving opioid therapy were identified from a longitudinal insurance claims database. An algorithm was used to identify patients receiving opioid therap...