Mai Kabayama

Mai Kabayama
Osaka University | Handai · Department of Health Sciences

PhD

About

122
Publications
5,874
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
528
Citations
Citations since 2017
112 Research Items
514 Citations
2017201820192020202120222023050100150
2017201820192020202120222023050100150
2017201820192020202120222023050100150
2017201820192020202120222023050100150
Introduction
Skills and Expertise

Publications

Publications (122)
Article
Background: Frailty increases the risk of negative health-related events, such as falls, disability, hospitalizations, and death. Although the association between oral health and physical frailty is well established, the relationship between oral health and psychological frailty has not yet been investigated. Therefore, we conducted a cross-sectio...
Preprint
Full-text available
Background With the aging of the population, it is becoming increasingly important to maintain adequate lipid levels to prevent atherosclerotic cardiovascular diseases (CVD). In older populations, the association between CVD and lipids is controversial. We investigated the association between lipid levels and CVD onset in a community-dwelling older...
Article
We investigated the associations of visit-to-visit variability(VVV) of blood pressure (BP) with clinical events (death, hospitalization, falling) in older patient around 85 years old receiving home medical care. This study was performed in OHCARE (Osaka Home CAre REgistry), which is a prospective cohort study targeted old patients receiving home-ba...
Article
It is well known that excessive salt intake is associated with hypertension (HT) and salt intake reduction lowers blood pressure. However, the knowledge of salt intake and blood pressure in the older people is not sufficient. This study aimed to clarify the relationship between salt intake and blood pressure among community-dwelling Japanese older...
Article
Hypertension, dyslipidemia, and those combinations are very common in older adults. However, the association between cognitive decline and the combination of hypertension and dyslipidemia in older adults is still controversial. Therefore, we investigate the association between cognitive decline and hypertension, dyslipidemia, and their combination...
Article
We clarify the status of home blood pressure (HBP) measurement during the first 90 days after recommendation of self-measurement and recording among community residents and factors associated with everyday-measurement. The study subjects were 677 participants from the intervention group of NOSE study, a intervention study of HBP measurement in comm...
Article
Preventing illness and promoting health is important for prolonging healthy life expectancy, and it also leads to the reduction of medical and long-term care costs. As Japan has entered a super-aged society, prevention of CVD, which causes stroke and dementia, the main causative diseases of the need for long-term care, is becoming more important. I...
Article
Short sleep duration and poor sleep quality in middle age have been reported to affect blood pressure(BP) control. However, the association between sleep duration, sleep quality and BP control is controversial in older adults with hypertension taking antihypertensive drugs. The aim of this study was to investigate this association in 70–80-year-old...
Article
This study examined participants’ health-related awareness, changes in health consciousness, and their spillover effects observed through community-wide home blood pressure (BP) monitoring intervention. This study was based on an ongoing community-based intervention study in Nose, Osaka, which was designed to assess the effect of home BP measuremen...
Article
The purpose of this study was to assess the association between blood pressure (BP) related indicators and physical frailty among the Japanese community-dwelling elderly. The present cross-sectional analysis was based on an ongoing community-based intervention study in Nose, Osaka, which was designed to assess the effect of home BP measurement on p...
Article
Few studies have investigated weekly variations in long-term home blood pressure (BP) measurement. The aim of this study was to examine the intra-week variability and the difference in the day of the week on long-term home BP with or without antihypertensive medication. This study was based on an ongoing community-based intervention study in Nose,...
Article
To determine the association between skeletal muscle mass and systolic blood pressure decline over a 5-year period in older adults over 75 years old. Of those who got health checkups at private A clinic from May 2020 to March 2021, 118 subjects for whom data on systolic blood pressure (SBP) levels consequently collected for five years were included...
Article
Full-text available
Background Chronic kidney disease (CKD) has few objective symptoms, and it is difficult to make an early diagnosis by using existing methods. Therefore, new biomarkers enabling diagnosis of renal dysfunction at an early stage need to be developed. Here, we searched for new biomarkers of CKD by focusing on kidney-derived proteins that could sensitiv...
Preprint
Full-text available
Background: Factors associated with weight loss in community-dwelling older people have been reported in several studies, but few studies have examined factors associated with weight loss by age groups. The purpose of this study was to clarify factors associated with weight loss by age in community-dwelling older people through a longitudinal study...
Article
Full-text available
Background: The oldest old, defined as those aged 90 or over, is now the fastest-growing population sector. This study aimed to determine reference values for several physical performance measures (PPMs) among 90-year-olds using internationally standardized measurements and to clarify the characteristics of these indices by comparing their results...
Article
Full-text available
The Japanese government has implemented a new screening program to promote measures to avoid worsening lifestyle-related diseases and frailty among the older population. In this effort, the government formulated a new health assessment questionnaire for the screening program of old-old adults aged ≥75 years. The questionnaire comprises 15 items, of...
Article
Objective Tuberculosis (TB) patients are discharged after confirming their non-infective status. However, elder-care facilities often refuse to admit discharged TB patients. As no study has investigated anxiety among elder-care facility employees, we aimed to identify anxiety-associated factors among elder-care facility employees regarding the post...
Article
Aim: The late-stage medical care system for older people provides medical examinations, including questionnaires for frailty. We examined whether or not this approach is useful in clinical practice. Methods: We used this questionnaire for the screening of frailty as follows: according to the manual prepared by the Japan Geriatrics Society, each que...
Article
Full-text available
Older adults face the concern of developing frailty and sarcopenia due to an inactive lifestyle during the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to reveal the preventive behaviors taken by older adults who perceived a decline in physical fitness during COVID-19 and analyze the background factors which promoted such behavior...
Article
Background Previous studies have shown the social support-mental health associations varied in different bonding social networks. However, a further study is needed to determine these network-specific associations for mutually supportive interaction in a wider social network include bridging relationship members. Method We conducted a self-reporte...
Article
Full-text available
Some studies reported that home blood pressure (HBP) monitoring was conducted by community-dwelling older people themselves, but there have been few studies on HBP including very old populations aged over 90 years old. Thus, the aim of the present study was to clarify the current situation of white-coat and masked phenomena defined by on-site and h...
Article
Full-text available
Background To answer whether older adults' cognitive function benefits from ICT use, we (1) examined the relationship between ICT use and cognitive decline during the COVID-19 pandemic and (2) explored the potential role of ICT use in mitigating the relationship between loneliness, social isolation, and cognitive decline among community-dwelling ol...
Article
Full-text available
Background Older adults were expected to experience a decline in physical activities and an increase in social isolation during the COVID-19 pandemic. Methods We investigated the changes in living conditions of 508 older adults (79.70 years ± 0.88) before (from July to December 2019) and during (in August 2020) the pandemic. We compared the mean s...
Preprint
Full-text available
Background The oldest old, defined as those aged 90 or over, are now the fastest-growing population sector. This study aimed to determine reference values for a number of physical performance measures (PPMs) among 90-year-olds using internationally standardized measurements and to clarify the characteristics of these indices by comparing their resu...
Article
Objectives The aim of this cohort study among community-dwelling older adults aged over 70 years was to investigate the influence of occlusal support on tooth loss, and to determine predictive factors for tooth loss for each occlusal support category using multilevel analyses. Methods Participants were 812 older adults who completed the baseline s...
Article
Full-text available
Background The relationship between moderate alcohol drinking or other alcohol drinking patterns such as frequency, beverage type, and situation of drinking and cognitive function is not sufficiently clear in older people. The purpose of this study was to investigate the association between alcohol drinking patterns and cognitive function in commun...
Article
Full-text available
Aim: The aim of this study was to clarify the association between dietary protein intake and decline in the estimated glomerular filtration rate (eGFR) among Japanese older adults. Methods: We used the data of the Septuagenarians, Octogenarians and Nonagenarians Investigation with Centenarians (SONIC) study, an ongoing narrow-age range cohort st...
Article
Full-text available
Grip strength and walking speed are considered to be important indicators of physical frailty. However, no study has contemporaneously examined any association of multiple oral functions with grip strength and walking speed. The purpose of this study was to examine which oral functions are associated with muscle strength (grip strength), physical p...
Article
Aim: To prevent the transmission of the novel coronavirus [COVID-19] and stop its spread, a state of emergency was declared from April to May 2020. People were encouraged to refrain from outings and reduce their contact with people. The purpose of this study was to examine the subjective changes in the amount of activity under COVID-19 crisis among...
Article
Aim: We investigated seasonal variations in blood pressure (BP) and factors related to these variations among older patients receiving home medical care. Method: A total 57 patients ≥ 65 years old receiving home medical care who participated in the Osaka Home Care REgistry study (OHCARE), a prospective cohort study, were included. We investigated t...
Article
Japan will face a super-aged society in the near future, in which 40% of the population will be over 65 years of age. However, prolongation of life expectancy is inevitably associated with greater numbers of frail old people who need help or assistance in their daily activities. The percentage of the old-old population in 2020, comprising more frai...
Article
Full-text available
Background Considering the increased numbers of Chinese nurses in Japan, we hypothesized that Chinese nurses in Japan are confronted with many difficulties, although few studies have been performed. Therefore, in-depth analyses of their experience to explore significant factors and aspects are required. Objectives To clarify the problems and diffi...
Article
Aim: We examined the effect of "IkiIki Hyakusai Taiso" as way to prevent the physical decline in community-dwelling elderly in Nose Town, Osaka Prefecture. Methods: Participants were community-dwelling elderly who participated in the Preventive Care program "IkiIki Hyakusai Taiso" from October 2015 to June 2019 in Nose Town, Osaka Prefecture, Japan...
Article
Full-text available
Periodontal disease is a chronic inflammatory condition that affects various peripheral organs. The periodontal inflamed surface area (PISA) quantifies periodontitis severity and the spread of inflammatory wounds. This study aimed to investigate the association between PISA and high-sensitivity C-reactive protein (hs-CRP), a systemic inflammation m...
Article
Full-text available
The G allele of FOXO3 gene (Single nucleotide polymorphism – SNP; rs2802292) is strongly associated with human longevity. However, knowledge of the effect of FOXO3 in older populations, men or women, with heart disease is limited. This cross-sectional study in Japan included 1836 older adults in the 70 and 80-year-old groups. DNA samples isolated f...
Article
Full-text available
Objective To evaluate the effectiveness of the nurse-led alcohol guidance to control home blood pressure in the morning (HBP) among male patients with hypertension during outpatient visits. Method We enrolled 53 male patients with an HBP of ≥ 135/85 mmHg with excessive drinking (alcohol ≥210 g/week or ≥60 g/day habitually) among outpatients in a r...
Article
Objectives: To determine any independent influence of occlusal force and of number of natural teeth on decline in body mass index (BMI) among older Japanese adults. Design: Longitudinal study over a 3- to 6-year period. Setting: Urban and rural area in Japan. Participants: Independently living Japanese adults aged 69-71 years and 79-81 years...
Preprint
Full-text available
Background and Objectives: To deepen the understanding of processes underlying older adults’ behavior during the COVID-19 pandemic, we investigated associations among affective (anxiety about the coronavirus), cognitive (perceived risk of infection and fatality), and behavioral (engagement in preventive behaviors) variables. We also examined how th...
Article
Background: Physical function is a strong predictor of the adverse outcomes of cardiovascular disease in older populations. However, studies of healthy older people on the prevention of coronary heart disease (CHD) are very limited. Objectives; We prospectively examined the association of walking speed and handgrip strength with CHD in the communit...
Article
Age-related changes in affect have been described in developmental sciences, and the majority of these studies have focused on long-term intraindividual changes over years. However, evidence on short-term intraindividual variations over days remains limited. Using a daily diary method, we examined age differences in intraindividual variability in e...
Article
Full-text available
Background: Although early detection of cognitive decline has a significant relation to improving the quality of life of dementia patients, this early detection has been difficult due to requires of neuropsychological tests which people generally take when they notice their cognitive impairment. The timing of patients’ notice was reported to be wor...
Article
Aim The association between serum uric acid (UA) and atherosclerosis in old people is controversial. Therefore, in this study, we clarified this association by assessing serum UA and common carotid atherosclerosis examined by carotid ultrasound in community‐dwelling older people in their 70s, 80s and 90s in the SONIC study. Methods A cross‐section...
Article
Periodontal disease and arteriosclerotic disease are greatly affected by aging. In this study, the association of conventional risk factors and periodontal disease with atherosclerosis was longitudinally examined in Japanese older adults. Subjects in this study were 490 community-dwelling septuagenarians (69–71 years) randomly recruited from the Ba...
Article
Full-text available
Following publication, the authors asked to add the following institution to the affiliations of author Madoka Matsushita: Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine Both the PDF and HTML versions of the Article have been updated accordingly.
Article
Some studies reported that excessive blood pressure (BP) control was not appropriate for older people, especially from the viewpoint of quality of life and maintaining sufficient blood flow for tissue perfusion. However, the lower limit of the target BP is still unclear, and there has not yet been a sufficient consensus. Therefore, we investigated...
Article
Full-text available
Background: Preventing the need for long-term care (LTC) by identifying physical function risk factors are important to decrease the LTC burden. The objective of this study was to investigate whether grip strength and/or walking speed, which are components of the frailty definition, are associated with LTC in community-dwelling older and oldest pe...
Article
Aim: Heart diseases and social factors are associated with physical frailty, but there are few studies of older people living in the community. Consequently, the aim of this study was to examine the association between heart diseases, social factors and physical frailty in community-dwelling older populations including the oldest-old people. Meth...
Article
Full-text available
The aim of this study was to determine the effectiveness of the Smart Life Stay (SLS) program, which is an experience-oriented stayover program, in combination with health tourism and mandatory health guidance on glucose metabolism after 2 years. The participants of the SLS program (n = 792) were recruited from a database of 23 medical insurers. Th...
Preprint
Full-text available
Objective: Physical function is a strong predictor of the adverse outcomes in older populations. We prospectively examined the association of walking speed and handgrip strength with CHD in the community-dwelling older populations. The study cohort in Japan included 1272 older people free from heart disease at the baseline. Physical function was id...
Article
Despite the clinical usefulness of self-measured home blood pressure (BP), reports on the characteristics of home BP have not been sufficient and have varied due to the measurement conditions in each study. We constructed a database on self-measured home BP, which included five Japanese general populations as subdivided aggregate data that were clu...
Article
Full-text available
We investigated the association of systolic blood pressure (SBP) level with physical frailty and cognitive function in community-dwelling older Japanese. Using the ‘Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians’ survey as the baseline, we performed a cross-sectional analysis of people aged 70 ± 1 (n = 1000), 80 ± 1 (...
Preprint
Full-text available
Background The association of social support with mental health for the older adults has been well documented; however, object-specific support was rarely discussed. This study examined the relationships of multiple aspects of social support, especially focusing on objects of social support, across different aging stages. Methods We conducted a sel...
Article
Aim The incidence of anemia increases with aging, and it is considered to affect mortality through complex pathophysiological outcomes. Although it has been suggested that self‐rated health may also contribute to the prognosis of anemia in older people, the relationship between anemia and self‐rated health is not well understood. This study thus ex...
Preprint
Full-text available
Objectives Physical frailty is geriatric syndrome and can increase the risk of adverse outcome in the older population. Heart diseases are associated with physical frailty but a few studies in community-dwelling old population. Therefore the aim of this study was to examine the association between heart diseases, social factors, and physical frailt...
Article
Full-text available
Objectives: We examined the associations of weight loss and low serum albumin level with death in community-dwelling elderly, as well as related factors by a systematic review with a meta-analysis. Methods: We searched MEDLINE, Cochrane Library (CENTRAL), Web of Science, and CHINAL for articles on cohort studies investigating the association of wei...
Article
Full-text available
Aim: Several studies have reported a negative correlation between depressive symptoms and family caregivers' (FCs) subjective sleep status. However, there is a paucity of information on the association between objective/subjective sleep status, care burden, and related factors. Methods: Participants were 23 pairs of care receivers (CRs; Mage = 8...
Article
Full-text available
Background: Cognitive impairment is a major health concern among older and oldest people. Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest is still lagging behind. Therefore, the aim of this stud...
Preprint
Full-text available
Background: Cognitive impairment is a major health concern among older and oldest people.Moreover, stroke is a relevant contributor for cognitive decline and development of dementia. The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest is still lagging behind. Therefore, the aim of this study...
Preprint
Full-text available
Background: Increasing older people make a cognitive impairment is a major health concerns among older and oldest people. Moreover, the stroke is a relevant contribution for cognitive decline and development of dementia.The study of cognitive decline focused on stroke as the important risk factor by recruiting older and oldest still lagging behind....
Article
Although high blood pressure (BP) and BP variability have been reported to be associated with cognitive impairment, few studies have investigated the association between home BP (HBP) and cognitive function in the oldest-old. The aim of this study was to evaluate whether the value of and the day-to-day variability in HBP was associated with cogniti...
Article
Objectives: Many older people lose their teeth. However, few studies have examined whether the number of remaining teeth or the amount of occlusal support is more important for tooth loss that occurs in older age after adjusting for systemic factors. The purpose of this study was to investigate comprehensively the factors related to tooth loss ove...
Article
Full-text available
Background: Instrumental Activities of Daily Living (IADL) is an indicator of whether a community-dwelling elderly can live independently. IADL decline was reported to be associated with aging and depression. The present study aimed to investigate whether the association between IADL decline and depressive symptoms differs with aging, using two ag...
Article
Aim: To clarify factors associated with changes in care needs level and mortality among disabled older people receiving home medical care over a period of 2.5 years. Methods: The study included 179 participants, aged ≥65 years, receiving home medical care, who consented to join the Osaka Home Care Registry study. The main outcome was changes in...
Article
Purpose: Dementia is a growing health problem for countries with aging populations, but few effective dementia treatments are available. However, there is increasing interest in oral health as a modifiable risk factor in interventions to prevent cognitive decline. This study aimed to investigate the impact of oral health on the decline of cognitiv...
Article
Full-text available
Aim: The present study investigated the behavioral and psychological symptoms of dementia (BPSD) and pharmacological therapy among elderly people with dementia who received home medical treatment. Methods: This study was part of the Osaka Home Care Registry study (OHCARE-study). Participants were >65 years old with dementia. Demographic and medical...
Preprint
Background Increasing in the older people and a decline in mortality after stroke, the rate of post-stroke cognitive decline has increased. The relationship between risk factors and post-stroke cognitive decline in dwelling old and oldest people who living in the community especially with asymptomatic stroke have to be elucidated. Therefore, the ai...
Article
Objective As smoking is not allowed at most medical institutions, it is important to provide smoking cessation support for smoking patients. However, the lack of human resources is the biggest problem for smoking cessation support. Moreover, it is concerned that there are little supports for non-Japanese smokers. According to the ministry of health...
Article
Full-text available
Despite the wide use of automated devices for the self-measurement of home blood pressure (BP), no evidence is available regarding the accuracy of such devices in oldest-old populations. The aim of this study was to validate the accuracy of the automated oscillometric upper arm-cuff BP-monitoring device according to an international protocol in old...
Article
Aim: The objective of this study was to clarify the relationship between cognitive function and the serum albumin/globulin ratio (A/G ratio) in community-dwelling Japanese older adults. Methods: Randomly extracted residents in both urban and rural parts of Japan were enrolled in this study. A total of 1827 participants with a mean age of 70 or 8...
Article
Full-text available
Aims/Introduction Hyperglycemia is a risk factor for sarcopenia when comparing individuals with and without diabetes. However, no studies have investigated whether the findings could be extrapolated to patients with diabetes with relatively higher glycemic levels. Here, we aimed to clarify whether glycemic control was associated with sarcopenia in...
Article
Objective To investigate the association between posterior occlusal support by residual teeth and the reduction in walking speed in 80‐year‐old Japanese adults using propensity score matching. Background data discussing the present status of the field Previous studies have demonstrated an association between oral status and motor function; however...
Article
Background: Chronic and lifestyle-related diseases and social status were reported to be associated with long-term care (LTC). The social factors should be treated as social sub-groups of which characteristics show social profiles. However, few previous studies considered that. The present study aimed to investigate the associations between LTC an...
Article
Introduction: Social capital (SC) has been said to have the positive and negative effects on mental health among older people. This mixed effect can be due to the regional differences (e.g. national economic status, ethnic diversity). In addition, the effects of SC have been considered to vary depending on the homo/heterogeneity of neighborhoods. P...
Article
Background There is increasing evidence of causal links between poor mastication and cognitive impairment, but possible effects of dietary hardness, which clearly affects mastication, on cognitive function is unknown. Objective We investigated the hypothesis that hardness of the habitual diet would be associated with cognitive function among older...