Mahmoud Bahmani

This experimental trial was designed to evaluate the anti-leech effect of methanolic extract of Peganum harmala L. plant as well as niclosamide, albendasole, pyrvinium, furazolidone and sulfadimidine. In an experimental study the methanolic extract of Peganum harmala L. aerial parts was prepared by maceration method and the amount of total phenolic...

In the present experimental study, anti-parasitic effect of Zingiber officinale on Limnatis nilotica leech population was evaluated. After treating the leeches with Zingiber officinale (32 × 104 ppm) and the positive controls; Chlor (4 × 106 ppm), Formalin %37 (4 × 103 ppm) and Savlon (4 × 103 ppm) for 30 min, the mean death time of L. nilotica was...

Background and aims: Leeches biting is of newfangled zoonosis parasitic disease that the most dangerous complication with their biting is incidence of anemia. There have not been found a drug for treatment the leech's complications in the pharmacopeia of different nations. Onion and Garlic are of the most widely used plants in the traditional medic...

Leech infestation can cause various clinical symptoms in human and animals. There are a few reports about this infestation in the world. In this report, we represented two cases of leech infestation of Limnatis nilotica in domestic kid and ram with anorexia, little respiratory disorders and restlessness in Dehloran city, Ilam province, west of Iran...

Common features of leeches are nature parasitic and most important complication with infestation in host is anemia. In different Nations Pharmacopeia not registered drug for treatment of complications with leech in the world. This study prepared methanolic extract of Matricaria chamomilla L. and several selected chemical drugs such as Febantel, Meb...

Background: Every year, drug poisoning is the most prevalent reason for referring patients to medical centers. This study aimed to evaluation of morphine, methadone, digoxin, and dronabinol poisoning in Shahid Mostafa Khomeini Hospital in Ilam. Methods: In this In this Cross-sectional study, patient samples suspected of morphine, methadone, digo...

Introduction: Every year, drug poisoning is the most prevalent reason for referring patients to medical centers. According to the available reports, pharmaceuticals are unfortunately responsible for the rise in poisoning as the leading cause of mortality over the last 7 years until 2014. In recent years, the country's legal drug organization has r...

Infertility is a major problem in modern society that affects a significant number of couples around the world. Heavy metals and a number of other factors have been causally linked to infertility. The aim of this study was to determine the effect of heavy metals lead, cadmium, and copper on the epidemiology of male and female infertility. Searches...

Objective: Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects one in every 15 women worldwide. This disorder is mainly characterized by increased levels of male hormones (androgens), acne, and hirsutism, and can lead to long-term insulin resistance, miscarriage, or even infertility in women. PCOS is a disorder that can be treat...

Objective: To evaluate the anti-bacterial activities of titanium dioxide (TiO) nanoparticles of Origanum (O.) vulgare and Hypericum (H.) perforatum extracts, carvacrol and hypericin against Staphylococcus (S.) aureus. Methods: In this study, TiOnanoparticles of O. vulgare and H. perforatum extracts, carvacrol and hypericin, were prepared and the...

Finding more efficient agents with fewer side effects for the treatment of burns has been a concern for researchers. The current study aims to assess Aloe vera (L.) Burm.f. and Vitis vinifera L. extract combination (AVEC) effects on wound healing in rats compared with silver sulfadiazine (SSD). Identification of individual polyphenols of the plant...

With the increase in the use of antibiotics and resistance against them, attention has been paid to natural remedies with the possibility of lower resistance and side effects. In this study, the essential oil of Loranthus europaeus Jacq. was identified chemically and the antimicrobial effects of the essential oil and extract on bacterial agents suc...

COVID-19, known as the “novel coronavirus disease 2019”, is a respiratory illness, and the causative pathogen is officially named as Sars-CoV-2, whose epidemic has spread rapidly worldwide. Thus, human-to-human transmission has reduced as people’s attention to health has increased and precautionary measures have been implemented. It is known that t...

Peganum harmala is a plant that belongs to the family Zygophyllaceae. In traditional medicine, this plant has therapeutic effects such as repelling intestinal worms, increasing sexual potency, increasing milk secretion, anti-rheumatism, regularizing, anti-parasitic, hypnotic, diaphoretic, anti-cancer and analgesic. The aim of this study was to iden...

Milk and dairy products are a major source of nutrition, especially for children, because they contain almost all of the nutrients. Consumption of milk and dairy products is high in developed countries and accounts for about 10%-20% of daily calories. Heavy metal poisoning is associated with a number of diseases, but if these heavy metals are found...

Wound healing is a process that starts with the inflammatory response after the occurrence of any damage. This process initiates by restoring the wound surface coating tissue, migrating fibro-blasts to form the required collagen, forming a healing tissue and finally, leading to contortion and extraction of the wound. Today, various drugs are used t...

Introduction Persian medicine (PM) is one of the oldest branches of medicine in the world. The purpose of this research was to analyze published articles about PM in the PubMed indexed journals. Method Articles indexing in the PubMed database (2015-2019) searched for keywords "Iranian traditional medicine", "Iranian medicine", "Persian traditional...

Chamomile has several variants, such as Anthemis Susiana Nabelek, Matricaria chamomilla L., Chamomilla recutita (L.) Rauschert, Matricaria suaveolens Koch and etc. Medicinal herbs, extracts and essential oils are of particular importance in the pharmaceutical, cosmetic and food industries. The phytoanalysis of these compounds is of particular impor...

Essential oils are aromatic compounds widely used in the perfumery, pharmaceutical and food industries. There are several methods to extract essential oils and extracts. These methods include distillation, pressure or scraping, pressing and razor technique, headspace solid-phase micro extraction (HS-SPME), solvent extraction, extraction by bioactiv...

Campylobacter (curved bacteria) is considered one of the most important and common zoonotic bacteria and the three leading bacterial causes of gastroenteritis and diarrhea. Antibacterial resistance is growing and expanding. The aim of this review article is to report anti-Campylobacter medicinal plants. For this purpose, the search terms consisting...

Objective Staphylococcus aureus, a Gram-positive bacteria, is ranked second among the causes of hospital infections and is one of the three main causes of food poisoning. In recent times, the spread of antibiotic resistance in S. aureus has become very worrisome. Therefore, research for new effective drugs is important. The present study aims to in...

Aim This study was designed to evaluate the synergistic activities of hydroalcoholic extracts of medicinal plants Origanum vulgare and Hypericum perforatum and their active components, carvacrol and hypericin against Staphylococcus aureus. Methods The synergistic effects of the plants, as well as carvacrol and hypericin, were examined using a chec...

Brucellosis is an old, infectious and common zoonosis whose causative agents are Gramnegative bacteria from the Brucella genus. Brucellosis is transmitted through direct contact with infected animals or using unpasteurized dairy products of goats, pigs, camels, sheep, buffalo and cows. Brucellosis is still the most common zoonosis in the world, wit...

Background and Aim: Currently, Giardia lamblia is the most common parasitic protozoan in many countries, including Iran, and the most important cause of diarrhea among travelers, children, and homosexuals. Chemical drugs could be used to treat giardiasis. These drugs can have carcinogenic effects and can lead to drug resistance, which is being repo...

Herbs have played an important role in the health and wellness of human. Nowadays, medicinal herbs are at the forefront of studies of medical science because of their importance in public health. Understanding the traditional and therapeutic effects of medicinal plants is important because they can be effective as a source of medication. Based on t...

Context: Documenting folk uses of wild medicinal plants provide an important baseline for the future novel drugs development and pharmacological evaluation. Aims: To document the traditional ethnomedicinal knowledge of Ilam city of Ilam Province, Iran Methods: Semi-structured interviews were carried out in the study area from 190 informants to docu...

Leishmaniasis is an important zoonotic parasitic disease in tropical areas. It is a neglected disease and is a great health catastrophe in Iran. Pentavalent antimony compounds are used for its treatment, but they have adverse effects. Therefore, the use of natural herbs with low adverse effects seems necessary for treatment of Leishmaniasis. In thi...

Linum usitatissimum L is traditionally used for relief of pain and inflammation. In this study, the analgesic and anti-inflammatory effects of this plant were evaluated. Xylene test was used for anti-inflammatory evaluation in which 48 mice were randomly designated into 6 groups of 8 each including: control, dexamethasone as positive control (15 mg...

Objective Probiotics such as lactobacilli prevent the development of a wide range of human and animal's pathogens. The aim of this study was evaluation of antagonistic effect of isolated lactobacilli from local dairy products against three standard strains of Staphylococcus aureus, Bacillus subtilis, and Pseudomonas aeruginosa. Materials and Metho...

Streptococcus agalactiae is a spherical and Gram-positive bacterium that causes postpartum sepsis, endometritis, chorioamnionitis and premature delivery in pregnant women. The use of herbs and natural ingredients for the treatment of various disorders has been common. The present review is a report on the medicinal plants with anti-Streptococcus ag...

Natural mineral water which todays attract more trend rather that tap water in urban societies and has been appreciated for high level hygiene. This study considered microbiological quality of packaged natural mineral water marketed in Lorestan province where 35 samples were purchased randomly, were tested for presence of different indicator microo...

Chitosan is a natural polysaccharide that has antioxidant properties. It can consider as an antioxidant agent in food supplements. In this study the effect of extraction methods on the antioxidant activity of chitosan was investigated. Three methods including enzymatic, acid and alkaline methods were applied for isolating the chitosan from shrimp w...

This study was conducted to determine the effects of dietary supplementation of peppermint ( Mentha piperita L.) on the performance of broiler chicks. 500 Ross broiler chicks were divided into 5 treatment groups of 4 replications in a completely randomized design format. The diets were ISO-caloric and ISO-nitrogenous ones and contained 1.5, 3, 4.5,...

Medicinal plants contribute greatly to increase the therapeutic properties of bee products such as honey, pollen, royal jelly, and propolis. In fact, the pharmaceutical value of honeybee products is associated with the plants that attract honeybees. In this study, pollinating plants used by honeybees were gathered and identified from different regi...

Background Infectious diseases have always been an important health issue in human communities. In the recent years, much research has been conducted on antimicrobial effects of nature-based compounds because of increased prevalence of antibiotic resistance. The present study was conducted to investigate synergistic effect of Carum copticum and Men...

Objective The Lactobacillus is a genus of lactic acid bacteria which are regularly rod-shaped, nonspore, Gram-positive, heterogeneous, and are found in a wide range of inhabitants such as dairy products, plants, and gastrointestinal tract. A variety of antimicrobial compounds and molecules such as bacteriocin are produced by these useful bacteria t...

Atherosclerosis is one of the most important cardiovascular diseases that involve vessels through the development of fatty streaks and plaques. Plant-based compounds can help treat or prevent atherosclerosis through affecting the involved factors. The main purpose of this review article is to investigate and introduce medicinal plants and their pot...

Background: Cutaneous leishmaniasis is a prevalent disease in tropical and subtropical regions of the world. It is transmitted by the parasite Leishmania through sand fly bites psychodidae families, flutamida subfamilies from human to human and animals. Cutaneous wounds usually occur with a small number of lesions but sometimes the number of lesion...

Background and objectives: Leishmaniasis is a parasitic zoonotic disease and the sixth most important tropical parasitic disease, according to the WHO reports. This disease causes a lesion with remaining scar. Case presentation: This case report presents a patient with cutaneous Leishmaniasis. A 35-year-old male patient weighing 83 kg, residing in...

Infectious diseases are among the most important common diseases worldwide that bring stupendous costs for human community. Medicinal plants are considered a rich source of antimicrobial agents and therefore can be used as antimicrobial remedies because of producing secondary metabolites. This article was designed to review the effective medicinal...

There are various treatment regimens including different antibiotics and antacid medications for eradicating Helicobacter pylori to compare the effectiveness of 7-day concomitant regime with classic triple regimen in eradicating H. pylori. In this randomized clinical trial, 206 dyspeptic patients proven H. pylori infection, attended to a gastrointe...

Hypercholesterolemia is the major risk factor for cardiovascular diseases. Considering the high prevalence of CVD in Khorramabad city, and the inhibitory effects of flavonoides on the LDL cholesterol oxidation, and the flavonoides present in Descurainia Sophia, the aim of this study was to compare the effects of Descurainia sophia and levostatin on...

Hypercholesterolemia is the major risk factor for cardiovascular diseases. Considering the high prevalence of CVD in Khorramabad city, and the inhibitory effects of flavonoides on the LDL cholesterol oxidation, and the flavonoides present in Descurainia Sophia, the aim of this study was to compare the effects of Descurainia sophia and levostatin on...

Background and Objectives Pseudomonas aeruginosa is a Gram-negative, aerobic bacterium found in water and soil. It is a normal flora in skin and gastrointestinal tract of human beings. P. aeruginosa as an opportunistic pathogen involved in nosocomial infections having multiple pathogenic factors and shows high rate of resistance to different antibi...

Diabetic nephropathy (DN) is a serious complication of diabetes mellitus, and its prevalence has been increasing in developed countries. Diabetic nephropathy has become the most common single cause of end-stage renal disease (ESRD) worldwide. Oxidative stress and inflammation factors are hypothesized to play a role in the development of late diabet...

Non-steroidal anti-inflammatory drugs (NSAIDs) are a group of drugs which are used for a wide variety of diseases including pain and inflammatory conditions such as osteoarthritis, rheumatoid arthritis, musculoskeletal disorders, and other comorbid complications. However, this group of drugs have undesirable effects such as peptic ulcer, bleeding a...

Background: Doogh is a popular dairy beverage in Iran which its main ingredient is yogurt. The aim of this study was evaluation of bacterial and fungal contamination of this product marketed in Lorestan province, West of Iran. Methods: A total of 200 doogh samples consisted of 150 commercial samples, including five different brands and also 50 home...

Introduction: The incidence of cardiovascular diseases (CVDs) is very high in human societies and their prevention and treatment are the most important priority in many countries. Hypertension makes an important contribution to the development of CVDs. Objectives: This study aimed to collect the ethno-medicinal knowledge of the traditional healers...

Diabetes mellitus can damage the eyes, kidneys, nerves and heart. Microvascular and macrovascular disorders are the leading causes of morbidity and mortality in diabetic patients. Hyperglycemia can increase the indicators of lipid peroxidation and oxidative stress in which free radicals have the main role in the pathogenesis of these complications....

Introduction: Kidney stones are the third most common urinary tract problems after urinary tract infections and prostate pathology. Kidney stones may cause extreme pain and blockage of urine flow. They are usually treated with medications that may cause a number of side-effects. Medicinal herbs are used in different cultures as a reliable source of...

The first step for identification of medicinal plants and their therapeutic effects is to determine their use by local people, traditional medicine books and personal experiences. The aim of this study was to document the medicinal plants used as analgesic, sedative or narcotic agents by local residents of Dehloran, Iran. Interviews conducted with...

Autism is a neurodevelopment disorder that causes disruption in communication, behavior and social interaction, and influences all aspects of child development. Families of autistic children are involved with it more than families of children with Down syndrome and mental disorders. The causes of Autism include psychosocial, immune, genetic and bio...

Prostate cancer is one of the most dangerous diseases in men worldwide. The apoptotic factors such as BID, BIM and APAF1 have a main role in inducing apoptotic pathways. Some of the compounds can active this apoptotic factors. In this study, this notion was investigated by the use of the comet assay technique and molecular dynamics simulations....

Introduction: Public and occupational exposure to electromagnetic fields due to the growing trend of electronic devices may cause adverse effects on human health. This paper describes the risk of mutation and sexual trauma and infertility in masculine sexual cell by mobile phone radiations. Methods: In this study, we measured the emitted dose fr...

Objective: Food and nutrition services are one of the major sources of chemical and biological contamination. It has been anticipated that more than 70% of infectious diseases establish after consuming contaminated foods. Sanitary quality control seems more imperative considering that the confections cover a large proportion of food products in Ira...

Objective: Wheat is a strategic food crop in Iran. General consumption of wheat enhances the public health risk of probable contamination in the wheat products. Wheat is also exposed to different types of the microbial, fungal and chemical agents which could spoil it. This investigation intends to examine products of the flour milling factories for...

Objective: Bacterial contamination and food poisoning is one of contemporary issues in the early years which many governments like Iran allocate some million dollars a year to medical and social treatment to prevent the implications. Methods: This paper aims to determine the bacterial load in pasteurized milk, produced for Loerstan province market...

The number of women who give birth to their child via cesarean section is increasing in both developed and developing countries. This study was aimed to review the medicinal herbs effective in relieving labor and cesarean section pain. In this study the terms medicinal herbs, extract, essence, labor, and pain were searched in citation databases inc...

The application of herbs, herbal distillates and other herbal products for curing and healing wounds and burns has a long history in many countries. In countries such as India, Iran and China traditional medicine has a long history. There is valuable information of unknown forest herbs for curing wounds and ulcers. The main aim of this paper is ide...

Medicinal plants are a good source for preparation of new drugs. Aloe vera [L.] is one of the valuable medicinal plants native to hot and dry zones and is usually planted outdoors in hot areas. Currently, various products obtained from this plant are produced in the food, pharmaceutical and cosmetics industries all over the world. Various products...

Antibiotic resistance is growing and has limited ability of physicians to treat some infectious diseases. Discovery of new antibiotics or semi-synthetic derivatives affecting on resistant infections are main objectives for treatment of infectious diseases. The aim of this study was to investigate antimicrobial activity of Hydro-alcoholic extracts o...

Peptic ulcer is a lesion of gastric mucosa and submucosa or duodenum caused by increased secretion of gastric acid due to alcohol consumption, nonsteroidal anti-inflammatory drugs, continuous and prolonged hunger, continued stresses, Helicobacter pylori infection, and poor diet. In the present review article, the most important medicinal plants nat...

Shigella is a gram-negative intracellular pathogen which causes bacillus diarrhea in humans. Besides clinical and gastrointestinal diseases, shigella causes food poisoning. In Iran, medicinal plants are used to treat infectious diseases. In this review article, the native medicinal plants to Iran that are effective on shigellosis were reported. For...

Thymol (C 10 H 14 O) is a monoterpene which is considered a phenolic component and is present in many vegetable oils. Thymol is an aromatic essence which is known as disinfectant in traditional medicine. Thymol is found in plants and has properties such as antibacterial, antipyretic, antispasmodic, antifungal, antioxidant, and hepatorotective, anti...

Parasitic diseases are a major public health proble m with negative effects on the lives of hundreds millions of people around the world, especially in tropical dev eloping countries. WHO estimates that three and a h alf billion people worldwide are infected with parasitic diseas es that between four hundred and fifty million people suffer from thi...

Background: Listeria monocytogenes is an important bacterial agent of food spoilage and cause of listeriosis. Recently, plants have been increasingly considered as alternatives to chemical drugs for preserving foods. Therefore, it is highly important to study their antibacterial effects. This study was conducted to investigate the antibacterial eff...

Inflammasome activation is mediated by (NOD)-like receptors (NLR) proteins that respond to stimuli. Among NLRs, NACHT-LRR and PYD domains-containing protein 3 (NLRP3) senses the widest array of stimuli. NLRP3 inflammasome has an important role in the development of many inflammation disorders. Regarding the significance of inflammatory diseases, an...

Inflammasome activation is mediated by (NOD)-like receptors (NLR) proteins that respond to stimuli. Among NLRs, NACHT-LRR and PYD domains-containing protein 3 (NLRP3) senses the widest array of stimuli. NLRP3 inflammasome has an important role in the development of many inflammation disorders. Regarding the significance of inflammatory diseases, an...

Nowadays, increases in resistance of tumors to the current therapeutic agents have become a problematic issue. Therefore, efforts to discover new anticancer compounds with high sensitivity of cancer cells are extending. Animal and laboratory researches have shown that exogenous antioxidants are able to help prevent the free radical damage associate...

There was an important period of time for developing medical sciences between 9th to 12th century ADwhich is called as Islamic Golden Age (1). It was happened because of some Persian and Muslimphysicians’ efforts like Akhawayni (?-983 AD), Rhazes (865–925 AD), Haly Abbas (949-982 AD),Avicenna (980-1032AD), Jorjani (1042-1137AD), etc (2). Rhazes was...