Mahesh .S

Mahesh .S
  • PhD
  • Research officer at Central Council for Research in Ayurvedic Sciences

Drug development, Clinical trial, Ayurveda pharmacology

About

23
Publications
57,686
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19
Citations
Introduction
Dr. Mahesh S is working as Research officer in Central council for Research in Ayurveda sciences, Ministry of AYUSH. I was previously working as Assistant professor in the Department of Rasashastra and Bhaishajya kalpana [Ayurveda pharmacology] at Parul Institute of Ayurveda, Parul University, Gujarat. Former Research scholar of University of Debrecen, Hungary. My expertise lies in development and designing of new formulations and analysing the safety profile of Ayurvedic formulations.
Current institution
Central Council for Research in Ayurvedic Sciences
Current position
  • Research officer
Additional affiliations
August 2020 - December 2020
Parul University
Position
  • Professor (Assistant)
February 2019 - July 2019
University of Debrecen
Position
  • Researcher

Publications

Publications (23)
Article
Vatavidhvamsana Rasa (VVR)is a famous herbomineral formulation containing various processed metals, minerals and herbals and is mainly used in treating neurological and muscular diseases. Herbomineral formulations in Ayurveda are always under scrutiny for safety aspects due to the presence of heavy metals. This study is an attempt to evaluate the s...
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Mastitis, characterized by mammary gland inflammation due to microorganisms, significantly reduces dairy animal productivity by up to 70%. Clinical mastitis prevalence stands at 11%, with sub-clinical cases at a staggering 77%, highlighting its substantial impact on milk yield. Given the escalating concern of antibiotic resistance, exploring altern...
Article
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Introduction: As per WHO reports, 170 WHO member states have been practicing various indigenous traditional medicines. For the global reorganisation of Ayurvedic drugs advanced standardisation techniques may be involved to maintain quality assurance. Madhumalini Vasant Ras (MVR) is a well-known Ayurvedic herbo-mineral formulation used in the treatm...
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Osteoarthritis is characterized by deterioration of articular cartilage, marginal epiphyseal hypertrophy, subchondral sclerosis, and various biochemical and morphological changes in the synovium. Ayurveda offers remarkable help in this debilitating condition called Sandigata vata and reduces morbidity. Along with internal medications, Ayurveda prov...
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Medicated oils prepared according to the process explained in Ayurvedic literature like Shargandhara samhita are used for internal administration and local applications of different ailments. Medicated oils are prepared with sesame oil processed with a decoction of herbs and paste of herbs. Murivenna, is an Ayurvedic medicated oil used for acute in...
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Introduction: More than 100 million populations globally suffer from Osteoarthritis (OA) which is considered the leading cause of disability. The prevalence of OA knee in India is about 6% of total osteoarthritis. Therefore, there is a need for alternative and well-tolerable supplementary treatment which has no drug interaction with conventional dr...
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Hypothyroidism falls within the domain of dhatvagni mandyajanya vyadhi, which is characterized by impaired metabolism at the Dhatu (tissue) level. A sedentary lifestyle combined with high-calorie foods that require little energy expenditure can be the cause of a disrupted metabolism. This case of subclinical hypothyroidism is selected due to its pr...
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The present review explores the possible Rasayana properties of Chitraka, the dried mature root of Plumbago zeylanica Linn., within the framework of Ayurveda. Rasayana chikitsa, an integral component of Ayurvedic medicine, focuses on rejuvenation to achieve optimal physical, mental, and spiritual health. Chitraka, identified as both Kamya Rasayana...
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Inflammation is a complex process mainly comprises of three phases namely acute, sub-acute and chronic. In acute inflammatory conditions fluid and granulocytic cells accumulate at the site of injury because of the changes in small blood vessels. This response often activates systemic response such as leucocytosis, protein catabolism, fever and synt...
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Every science has its own set of principles known as basic principles. Druti is a basic principle of Rasashastra and remain as an important pharmaceutical process. There are various dosage forms like Churna, Guti, Vati, Kwatha, Bhasma, Pottali, Sindura etc described in the classics of Rasashastra and Bhaishajya Kalpana. Druti is one of the main yet...
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Rasaushadhis or rasa yogas are a potent group of herbo-mineral formulations well documented in Ayurvedic classical treatises.Vatavidhvamsana Rasa is a well-known herbo-mineral Ayurvedic formulation mentioned in Yogaratnakara which is also quoted in Ayurvedic Formulary of India (AFI). Vatavidhvamsana Rasa is a widely used herbo-mineral preparation i...
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Full-text available
Vatavidhvamsana rasa (VVR) is a well-known herbo-mineral formulation explained in classical ayurvedic text Yogaratnakara and also quoted in Ayurveda Formulary of India (AFI) and is mainly indicated for Vatika disorders. There is a lack of data regarding the standardization of pharmaceutical process and analytical profile of VVR. Aim: To prepare vat...
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Full-text available
Nasya is the administration of different types of medicines through the nasal passage in a systematic manner. It is administered in a wide variety of diseases and specifically in urdwajatrugata vikaras. Nasya is categorized into many types according to different acharyas. In present day, administration is in many forms like Marsha, Pratimarsha, Pra...
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Rasna Guggulu is a preparation mentioned for management of Gridhrasi by Chakradutta and has Rasna, Guggulu and Ghrita as its ingredients. It is having Ushna Virya, Vata hara as well as Vata Kapha samana properties so as to encounter the disease condition. Gridhrasi is a disease where shoola (pain) is a major symptom and which comes under vatavyadhi...
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Pain is a serious problem globally due to its high prevalence and is regarded as the fifth vital sign. The standard methods comprising of NSAID and opioid group, interventional methods and implantable methods; although often very effective, have known adverse effects on gastrointestinal, renal and cardiovascular systems and surgical risks. Ayurvedi...
Presentation
Toxicity study of an herbomineral preparation.
Article
Full-text available
ABSTRACT Background: Chyavanaprasa is classified under the group of Rasayana (Rejuvenator), where the main purpose is to maintain the body’s integrity for delaying the ageing process, enhances longevity and improves digestion. On account of increasing urbanization, the tendency is towards more and more dependence on readymade preparations. It is o...
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ABSTRACT A CRITICAL REVIEW ON AVALEHA KALPANA Mahesh S1*, Sheela Karalam B2, Aravind S3, Neethu S Pillai4 Avaleha is the most common secondary Kalpana (dosage form) which has been employed in various disorders and this product is gaining popularity due to its easy administration, palatability and longer shelf life. It is a semisolid preparation...
Article
Full-text available
ABSTRACT Background: Chyavanaprasa is one among the popular Ayurvedic preparations grouped under Rasayana, which incorporates more than forty botanicals. In order to ensure quality, safety and efficacy of Ayurvedic formulations available in the market like Chyavanaprasa, uniform method of preparation must be adopted by different GMP certified compa...

Questions

Questions (2)
Question
significance of testing reducing sugar and total sugar in various Ayurvedic formulations??
Question
What is the significance of testing reducing sugar and total sugar in various Ayurvedic formulations??

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