
Mahdi AyyariTarbiat Modares University | TMU · Department of Horticultural Science, Medicinal Plants Group
Mahdi Ayyari
Ph.D. of Phytochemistry
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68
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558
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Citations since 2017
Introduction
Additional affiliations
October 2008 - September 2013
September 2001 - July 2006
Publications
Publications (68)
The usage and benefits of Momordica charantia L. secondary metabolites in health and industry are undeniable. Researchers are trying to increase the valuable compounds of such plants by using various methods. In this study, the possibility of inducing an increase in the biosynthesis of diosgenin and other bioactive compounds in M. charantia by foli...
Spearmint essential oil (SEO), one of the economically valuable natural products, has special importance in the food, pharmaceutical, and perfumery industries due to its antifungal, antioxidant, and enzyme inhibitory properties. In this study, we optimized and evaluated the effect of three pre‐treatments on the extraction of SEO for quantity and qu...
Ethnopharmacological relevance
Ethnopharmacological studies for drug discovery from natural compounds play an important role for developing current therapeutical platforms. Plants are a group of natural sources which have been served as the basis in the treatment of many diseases for centuries. In this regard, Ceratonia siliqua (carob) is one of th...
Cold plasma (CP) is one of the emerging technologies capable of creating special capabilities in agricultural products by affecting their surfaces. This technique can increase the content of essential oil extracted from active ingredients, while reducing the microbial load of medicinal and aromatic crops. In order to investigate the effect of diele...
Pistacia atlantica Desf.is one of the main wild species of Pistacia in Iran and one of its products is an oleo-gum-resin briefly called Saqez gum. The effect of Ethrel injection (EI) on Saqez gum production was studied during summer 2018 at three habitats (Kuh-e Birk, Goharkuh and Mirabad) inSistan and Baluchestan province, Iran. Four treatments, 0...
Spearmint (Mentha spicata L.) is one of the most important species of the Mentha genus, many of which are produced commercially on a large scale. Agro-morphological and phytochemical properties of 25 Iranian spearmint landraces were evaluated. The landraces were found to be significantly diverse phenotypically in terms of the following: plant heigh...
مقایسه ترکیبات اسانس توده هایی از دوگونه Eryngium noeanum Boiss. وEryngium iranicum Mozaff. در ایران
Hyssop (Hyssopus officinalis L.) is one of the most important medicinal and aromatic crops (MACs) in the pharmaceutical, food and cosmetic industries. It has antioxidant, anticonvulsant, antifungal, antimicrobial, antihemolytic, antiulcer, antispasmodic and several other pharmacological activities. Determining suitable harvest time and most appropr...
Certain post-harvest processes of medicinal and aromatic crops (MACs) such as washing, drying, cutting and milling, decontamination, packaging, and warehousing are widely applied in the industry. However, the effects of some of them on the active ingredients have been less thoroughly studied. Changes in the essential oil (EO) content and compositio...
To evaluate the effect of infrared drying on color parameters, essential oil content and composition of German chamomile (Matricaria chamomilla L.), an experiment based on completely randomized design was carried out. Three different intensities of infrared; 125, 132 and 220 W in combination with three different air flows; 0.5, 1.0 and 1.5 m/s (a t...
This research aimed to investigate natural (shade and sun drying) and artificial drying methods (oven, vacuum, microwave, infrared and freeze-drying) on the spearmint essential oil (EO) quality and its trichomes. Fresh plant (control), shade dried, sun dried, freeze dried, oven dried at 40, 50, and 60 °C, vacuum dried at 40, 50, and 60 °C, microwav...
""This article was published in Eco-phytochemical Journal of Medicinal Plants."" Nepeta crispa Willd. Locally known as Mofarrah belongs to Lamiaceae family. It is an Iranian endemic self-growing medicinal plant to Alvand Mountains in Hamadan province. N. crispa has carminative, anti-inflammatory, antinociceptive, antibacterial and antifungal proper...
This manuscript was published in Iranian Journal of Horticultural Science. Abstract:
Pistacia atlantica with the Persian name “Baneh” is one of the main wild species of Pistacia in Iran. The exudate of this plant is an oleo-gum-resin that comes out of the outer layer of plant bark and is called “Saghez” in Iran. In this study, the content and chem...
PurposeAngiogenesis related abnormalities underlie several life-threatening disorders. Despite approved therapies, scientists have yet to develop highly efficient, low cost approaches with minimal side effects.Methods
We evaluated the antiangiogenic activity of 50% hydroalcoholic extracts of Pergularia tomentosa L. root and aerial parts along with...
In this study, Eryngium thyrsoideum Boiss. was collected from three regions Razjerd (Rz) (Qazvin province), Salavatabad (Sv) (Sanandaj, Kurdistan province), and Paygelan (Py) (Marivan, Kurdistan province) at 1700, 1780, and 1840 m above the sea level, respectively, and their volatile components were evaluated. The shade-dried plant materials were h...
Introduction: Coltsfoot (Tussilago farfara L.) from Asteraceae family is a perennial plant. T. farfara is native and widespread from Europe to Western and Northern Asia and North Africa. Coltsfoot distributed in wet mountainous regions of Iran, such as Azerbaijan, Tehran and Northern provinces. Its flowers and leaves have been used traditionally fo...
Blessed thistle (Cnicus benedictus L.) is an abundant resource with huge phytochemical and agronomic potentials. Their variation in response to agronomic techniques needs to be explored. Field studies were laid out to assess plant density and nitrogen fertilizer (N) effects on blessed thistle plant height, branches number (m⁻²), vegetative variable...
In order to investigate the effect of infrared radiation intensity and air velocity on some of the qualitative characteristics of hyssop (Hyssopus officinalis L.) during drying process, a factorial experiment was conducted in a completely randomized design with three replications. Infrared radiation intensity was investigated at three levels of 0.2...
To evaluate the drying methods on some color characteristics and essential oil of Ziziphora tenuior L., a factorial experiment based on completely randomized design was carried out. Two main treatments were as follows: shade drying (control), five microwave powers (100, 200, 300, 400 and 500 W) and two levels of infrared radiation intensities (125...
Coltsfoot (Tussilago farfara L.) from Asteraceae family is a perennial plant. Its flowers and leaves have been used traditionally for the treatment of cough, bronchitis and phlegm disorders. For this study the leaves and flowers of T. farfara were collected from seven major regions of Iran including Firoozkooh, Nur, Deylaman, Kaleybar, Namin, Damav...
Extracts of nine agricultural wastes prepared with five different solvents were assessed for their potential nematicidal activity against three nematode species, Aphelenchus avenae , Meloidogyne incognita and Pratylenchus neglectus , in in vitro condition. The 50% v/v hydro-ethanolic extracts showed the highest performance for two tested plant wast...
Satureja bachtiarica Bunge (Lamiaceae) is a medicinal plant native to Iran which is widely used in traditional medicine, as a spice and as a vegetable. Understanding the patterns of genetic variation and structure of natural populations of the plant will be crucial for breeding and management purposes. However, until now, there has been no molecula...
Holy thistle (Cnicusbenedictus) is an annual plant widespread from Asia Minor
to the Caucasus, including Syria, Iran, and Afghanistan, and in Mediterranean Europe.
Infusions and extracts of the aerial parts of this species are applied in traditional
medicine, as their aromatic‐bitter taste is assumed to increase appetite and
gastrointestinal secret...
Chromosomal studies are almost one of the main research topics in all plants,
speciallyin the medicinal plants which have not had asignificant genetic references. In
this case, Holy thistle (Cnicusbenedictus L.) From Asteracea family is a world's highly
valuable medicinal plant which the leaves and twigs of this plant are harvested at
flowering sta...
Developing alternative oilseed crops with acceptable seed yield and biomass production in low-yielding environments could be a part of sustainable agriculture management strategies. Field experiments were conducted in a semiarid region of Iran in 2013 and 2014 to determine the effects of N fertilizer rates and plant densities on growth, seed yield...
The LC-MS analysis of the MeOH extract of the aerial parts of Pergularia tomentosa led to the isolation of 23 compounds, of which the structures were elucidated unambiguously by NMR spectroscopic data analysis. Three new doubly linked cardenolides (4, 13, 14) along with several known cardenolides (1-3, 5, 7, 8, 15-23) and flavonol glycosides (6, 9-...
The acaricidal, oviposition deterrence and repellent activity of the subsequent nonpolar to polar extracts and fractions of Moringa peregrina (Forssk.) Fiori Agricolt. was studied against Tetranychus urticae Koch under laboratory conditions at 25 ± 1 °C, 65 ± 5% RH and 16:8 (L:D) h. Leaf disc method was employed to study the acaricidal activity of...
Background: Predicting the potential habitat of plants in arid regions, especially for medicinal ones, is very important. Although Pergularia tomentosa is a key species for medicinal purposes, it appears in very low density in the arid rangelands of Iran, needing an urgent ecological attention. In this study, we modeled and predicted the potential...
Aerial parts of blessed thistle (Cnicus benedictus L.) contain high amounts of phytochemicals and would be improved through varying agronomic management practices such as N rate and plant density. The objective of this study was to investigate the effect of different N fertilizer rates and plant densities on agronomic performance, photosynthetic ca...
High performance liquid chromatography data related to the concentrations of 12 phenolic compounds in vegetative parts, measured at four sampling times were processed for developing prediction models, based on the cultivar, grapevine organ, growth stage, total flavonoid content (TFC), total reducing capacity (TRC) and total antioxidant activity (TA...
In this study, a sensitive, accurate and reproducible high performance liquid chromatographic method was developed for determination of diosgenin from fenugreek (Trigonella foenum-graecum) leaves in 22 ecotypes of Iranian fenugreek. The obtained results showed that the highest concentration of diosgenin with 23.8 mg g-1 dw was found in Boshruyeh ec...
This study was undertaken to determine the total quantity of phenolic and flavonoids, as well as to find out about HPLC quantification of some individual phenolic compounds (i.e. chlorogenic acid, vitexin 2”-O-rhamnoside, vitexin, rutin, hyperoside, quercetin, and isoquercetin) in flower and leaves of 56 samples of different hawthorn species (Crata...
Tuberose volatile components were evaluated at four developmental stages of flowers extracted by Hydrodistillation Extraction (HE), Solvent-Assisted Hydrodistillation Extraction (SAHE), Accelerated Organic Solvent Extraction (AOSE) and Organic Solvent Extraction (OSE). Among the total number of 37 compounds, benzenoids such as benzyl benzoate via A...
An Ionic Liquid Based Ultrasonic Assisted Extraction (ILUAE) was developed for profitable extraction of diosgenin from fenugreek leaves. Imidazolium based ionic liquids (ILs) differing in their anions was used as catalytic agent for extraction procedure in order to optimize the diosgenin extraction. Five ionic liquids, concentration of ILs, reactio...
The majority of studies on grape secondary metabolism are focusing on the berry or stem and leaves phenolic composition. Although the composition of phytochemicals is known to be highly variable in different cultivars, the changes of this composition during vine growth in vegetative parts remain poorly understood. The present study was performed to...
Cardiac arrhythmias are major life-threatening conditions. The landmark discovery of induced pluripotent stem cells has provided a promising in vitro system for modeling hereditary cardiac arrhythmias as well as drug development and toxicity testing. Nowadays, nutraceuticals are frequently used as supplements for cardiovascular therapy. Here we stu...
This Abstracts Book is published in Persian, so All Abstracts extracted directly from IrHC2017 website (www.IrHC2017.org) Abstract Submission System. This Book of Abstracts, Prepared with minor editing and published, so corresponding and co-authors are responsible for the accuracy of their submitted abstracts. According to the IrHC2017 role, the se...
This is the abstract book of IrHC2017, so All Abstracts extracted directly from International Society for Horticultural Science (ISHS), ROSA Abstract Submission System. This Book of Abstracts, Prepared with minor editing and published, so corresponding and co-authors are responsible for the accuracy of their submitted abstracts. According to the IS...
Abstract
In this work, attempts were made in order to develop and evaluate a Computer Vision System (CVS) for nondestructive
characterization of saffron (Crocus sativus L.). Thirty-three saffron samples from different geographical
regions were tested. Fourteen color features were extracted using image analysis. Principal Component Analysis
(PCA) wa...
Background: Pergularia tomentosa L. has several traditional uses and biological activities which need to be more investigated.
Objective: In this study, some ecological and phytochemical properties of Pergularia tomentosa were assessed. The flavonoids and cardenolides in the aqueous extract of leaves were identified with LCMS techniques.
Methods: S...
This study was conducted to quantitatively characterize the aroma strength of saffron, Crocus sativus L. (Iridaceae), using an electronic nose. Thirty three saffron samples from different geographical regions were prepared for the experiments. Aroma strength of the saffron samples was determined based on ISO 3632 method as
directly relates to safr...
Medicinal plants are an important source of substances, which have been shown to induce non-specific
immunomodulatory effects. Salvia species showed anti-inflammatory properties. This study was carried out to investigate the role of hydroalcoholic and chloroformic extracts of salvia candidissima on hyperalgesia, edema, and serum TNF-αlevel during...
Evaluating the coloring strength of saffron, stigma of Crocus sativus L., is an important process in defining its quality and market price. In this work, attempts were made in order to develop and evaluate of a Computer Vision System (CVS) for non-destructive characterization of saffron based on color strength and the correlated chemical attribute,...
Background and objectives: Betulinic acid (BA), oleanolic acid (OA) and ursolic acid (UA) are well-known pentacyclic triterpenoids (PTs), which are produced by plants. They possess a variety of beneficial effects including anti-inflammatory, hepatoprotective, antitumor, anti-HIV, antimicrobial, gastroprotective, and antihyperlipidemic activities. I...
Background: Different species of Hyoscymaus are rich sources of tropane alkaloids, especially hyoscyamine and scopolamine. These compounds medicinally are important tropane alkaloids that exclusively are produced by plants.
Objective: Evaluation of hyoscyamine and scopolamine tropane alkalolids content in shoots and roots of Hyoscyamus species inc...
Introduction: The present study is the first assessment of the fatty acids of leaf and essential oil compositions of new three habitats of aerial parts of K. odoratissima. Methods: The aerial parts of K. odoratissima from the three habitats were dried. The essential oils were obtained by hydrodistillation for 3 h in a Clevenger-type apparatus, then...
The cross-conjugated and electrophilic dienone system of the humulane sesquiterpene zerumbone (1a) was modified by E/Z photochemical isomerization and/or by removal of homoconjugation with the isolated endocyclic double bond of the medium-sized ring. The site (C-6/C-9), mode (transient or irreversible), stoichiometry (single or twofold), and compar...
The essential oils from aerial parts of Ajania semnanensis Sonboli in two growing stages were isolated and their chemical constituents were identified. The oils were obtained by hydrodistillation and analyzed by gas chromatography–mass spectrometry (GC–MS) and GC–flame ionization detector (GC–FID). Twenty-three and sixteen compounds comprising 96.5...
Thymus persicus (Ronniger ex Rech. f.) Jalas is a valuable and endangered natural source of antitumor pentacyclic triterpenoids, i.e., betulinic acid, oleanolic acid and ursolic acid, which grows in northwest Iran. As the plant has a low propagation rate in nature, a suitable method for in vitro-propagation is needed. With the aim of identifying a...
Introduction: Inflammatory sympotoms such as edema and hyperalgesia were induced by some mediators like cytokines in response to irritant stimulus. The aim of this study was to investigate the effects of hydroalcholic and chloroformic extracts of Salvia Candidissima on hyperalgesia and edema during adjuvant-induced arthritis in rats.
O-Methyl (1), O-ethyl (2), and O-butyl (3) 4-[(α-L-rhamnosyloxy) benzyl] thiocarbamate (E), along with 4-(α-L-rhamnosyloxy) benzyl isothiocyanate (4) have been isolated from the aerial parts of Moringa peregrina. The compounds were tested for in vitro activity against Trypanosoma brucei rhodesiense and cytotoxicity in rat skeletal myoblasts (L6 cel...
Kelussia odoratissima Mozaff from Apiaceae family is an endemic and endangered ethnomedicinal plant from Iran. In this research the ecobiological background, phenological and chemical properties of this species in natural habitats is studied to understand its conservation biology as well as to predict its behavior under artificial cultivation. Resu...
A series of novel 2,3-dihydroquinazolin-4(1H)-ones was synthesized by a three-component reaction between dehydroabietylamine (DHA) diterpene, isatoic anhydride and different aromatic aldehydes in the presence of a catalytic amount of p-toluenesulfonic acid (13 mol%). Diastereomeric products were separated by preparative thin-layer chromatography an...
The antioxidant activities of ethanolic extract of six species of Tanacetum (T. budjnurdense, T. hololeucum, T. chiliophyllum, T. sonboli, T. tabrisianum, T. kotschyi) from Iran were examined by employing various established in vitro assay systems. The results showed that all Tanacetum extracts displayed antioxidant activities, with IC50 values ran...
A novel biopolymer-based hydrogel composite was synthesized through chemical crosslinking by graft copolymerization of partially neutralized acrylic acid onto the hydrolyzed collagen. The Taguchi method, a robust experimental design, was employed for the optimization of the synthesis based on the swelling capacity of the hydrogels. This method was...
Questions
Questions (3)
Which one is correct for naming a building which has the different agricultural subdivision or departments? Especially for the building that is separated from the general campus?
Is it different for any natural compound class to the other? for example is it different method for hydrolysis a glycoside from a flavonoids or a terpenoids or another classes?
I can not separate any comounds. I have isolate some but they were not pure. The one spot become more than 2 spot. I do not know how can I resolve them. They are very nonpolar which does not let me to use even reverse and Size exclusion chromatography. Can anybody help me in this topic.
Projects
Projects (5)
Creating a collection of different Iranian landraces of Mentha spicata L.