Magesh Sachidanandam

• DMLT., PGDWM., M.Sc.,M.Phil., Ph.D.,
• RA at King Institute of Preventive Medicine

HCV infection is emerging as a serious public health problem in Tamil Nadu. Chronic hepatitis C virus infection leads to liver fibrosis, cirrhosis and hepatocellular carcinoma (HCC). The transmission of HCV is primarily through exposure to infected blood. In this study, patient‟s serum samples were screened for IgG antibodies by ELISA and RNA ampli...

Nanotechnology pertains to the manipulation of materials at exceedingly small scales, specifically between 1 and 100 nanometers. Materials at this scale exhibit significantly different properties compared to the same materials at larger scales. An emerging trend is the utilization of nanoparticles (NPs) to address environmental issues. Metallic nan...

C-reactive protein (CRP) in the form of high sensitivity CRP (hs-CRP) is one of the better extensively used risk marker for the coronary artery disease (CAD) in clinical practice. Increased value of hs-CRP has been related with increased threat for the development of blood pressure, stroke, peripheral arterial disease, temporary ischemic attack and...

The objective of the study was to determine the prevalence and genotyping of RSV A and B in Chennai, Tamilnadu, south India. Human Respiratory Syncytial Virus (RSV) is one of the most important respiratory viruses causing acute respiratory tract infections amongst children. Based on genotyping of the attachment glycoprotein (G) gene, it is divided...

Background: Colon cancer is one of the major cancer causing morbidity and mortality around the world. Terminalia chebula is a rich medicinal value herb, which is widely employed for many diseases. T. chebula was used for the first time to synthesize rapidly silver nanoparticles. In this study, the methanolic extract of T. chebula reduced the silver...

In the present study, the various extracts viz aqueous, ethanol, chloroform and Petroleum ether of Biophytum sensitivum whole plant were evaluated for the anticancer activity against cancer cell lines. The cervical (Hela) and liver cancer (HepG2) cell lines were used to screen the in vitro anticancer challenging with the B.sensitivum extracts. Conc...

Green tea is rich in all the antioxidants. It has rejuvenating activity in our day to day life. The daily intake of green tea consumption per person was assessed as 2gm/day approximately. In this lieu, the present study was inducted to evaluate the anticancer efficacy of green tea against Human epithelioma of larynx cancer cell line. Ethanolic, chl...

Background: Diabetes mellitus patients thrive very hard to reduce their glucose levels by using various hypoglycemic agents. Many hypoglycemic agents cause side effects and fail to reduce glucose level, when they use for a long time. Folklore natural medicines will successfully act on many diseases without causing any side effects when it was consu...

Insulin receptor (IR) proteins were essential intracellular signaling peptides in the insulin action cascade. Insulin receptor substrate proteins (IRS-1and IRS-2) serve and regulate the insulin level in the normal insulin action. The broad role of IRS-1 and IRS-2 in cell growth and survival reveals a common regulatory pathway linking development, s...

Background: Acute lower respiratory tract infections (ALRI) are the major cause of morbidity and mortality in young children worldwide. Information on viral etiology in ALRI from India is limited. The aim of the present study was to develop a simple, sensitive, specific and cost effective Rapid multiplex PCR (mPCR) assay without post PCR hybridizat...