Magdalena Martínez García

Magdalena Martínez García
Instituto de Investigación Sanitaria Gregorio Marañón | IISGM · Neuroimaging group

Master in Neuroscience

About

12
Publications
1,670
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127
Citations
Introduction
I am a Neuroscience Ph.D. student at the Group of Neuroimaging of the Instituto de Investigación Sanitaria Gregorio Marañón of Madrid. My research focus is to unveil the structural and functional plasticity of the human parental brain. Through longitudinal neuroimaging studies, I seek to characterize the brain remodeling that takes place in both women and men during their transition into parenthood and to determine how such adaptations can deviate from normality and cause mental health problems.
Additional affiliations
June 2019 - present
Centro de Investigación Biomedica En Red del Área de Salud Mental
Position
  • Member
Description
  • Research of the structural and functional connectivity of the human brain through neuroimaging techniques: study design, magnetic resonance imaging analysis, and writing of scientific manuscripts.
January 2018 - present
Instituto de Investigación Sanitaria Gregorio Marañón
Position
  • PhD Student
Description
  • Characterize the remodeling of the human brain during pregnancy and childbirth both in mothers and fathers and determine its involvement in postpartum mental health.
June 2017 - December 2018
Centro de Investigación Biomedica En Red del Área de Salud Mental
Position
  • Research Assistant
Education
September 2015 - September 2016
September 2011 - September 2015

Publications

Publications (12)
Article
Objective: Neuroimaging studies in children with ADHD indicate that their brain exhibits an atypical functional connectivity pattern characterized by increased local connectivity and decreased distant connectivity. We aim to evaluate if the local and distant distribution of functional connectivity is also altered in adult samples with ADHD who have...
Article
Full-text available
Extensive research has established that fathers’ engagement in parenting benefits children, but few studies have described how fathers contribute to child development even before birth. In this article, we consider both direct and indirect pathways through which expectant fathers shape child development during the prenatal period. Regarding direct...
Article
Full-text available
There is a bi-directional transplacental cell trafficking between mother and fetus during pregnancy in placental mammals. The presence and persistence of fetal cells in maternal tissues are known as fetal microchimerism (FMc). FMc has high multilineage potential with a great ability to differentiate and functionally integrate into maternal tissue....
Article
Full-text available
Women that become mothers face notable physiological adaptations during this life-period. Neuroimaging studies of the last decade have provided grounded evidence that women's brains structurally change across the transition into motherhood. The characterization of this brain remodeling is currently in its early years of research. The current articl...
Article
Full-text available
Neuroimaging researchers commonly assume that the brain of a mother is comparable to that of a nulliparous woman. However, pregnancy leads to pronounced gray matter volume reductions in the mother’s brain, which have been associated with maternal attachment towards the baby. Beyond two years postpartum, no study has explored whether these brain cha...
Article
Full-text available
The transition into fatherhood is a life-changing event that requires substantial psychological adaptations. In families that include a father figure, sensitive paternal behavior has been shown to positively impact the infant’s development. Yet, studies exploring the neuroanatomic adaptations of men in their transition into fatherhood are scarce. T...
Article
In mothers, offspring cues are associated with a powerful reinforcing value that motivates maternal care. Animal studies show that this is mediated by dopamine release into the nucleus accumbens, a core component of the brain's reward system located in the ventral striatum (VStr). The VStr is also known to respond to infant signals in human mothers...
Article
Neuroimaging studies indicate that children with attention‐deficit/hyperactivity disorder (ADHD) present alterations in several functional networks of the sensation‐to‐cognition spectrum. These alterations include functional overconnectivity within sensory regions and underconnectivity between sensory regions and neural hubs supporting higher order...
Article
Objective: Impaired multisensory integration in autism spectrum disorder (ASD) may arise from functional dysconnectivity among brain systems. Our study examines the functional connectivity integration between primary modal sensory regions and heteromodal processing cortex in ASD, and whether abnormalities in network integration relate to clinical...
Article
COVER ILLUSTRATION This image aims to reflect the parallelism that exists between the morphometric brain changes that occur during pregnancy and those that take place during adolescence. The image has no copyright and the neurons were inspired in one of the Ramon y Cajal drawings.
Article
Mapping the impact of pregnancy on the human brain is essential for understanding the neurobiology of maternal caregiving. Recently, we found that pregnancy leads to a long‐lasting reduction in cerebral gray matter volume. However, the morphometric features behind the volumetric reductions remain unexplored. Furthermore, the similarity between thes...
Article
Previous studies have associated Attention-Deficit/Hyperactivity Disorder (ADHD) with a maturational lag of brain functional networks. Functional connectivity of the human brain changes from primarily local to more distant connectivity patterns during typical development. Under the maturational lag hypothesis, we expect children with ADHD to exhibi...

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Projects

Project (1)
Project
To understand, by means of magnetic resonance studies, the brain remodeling that mothers and fathers undergo during pregnancy and early postpartum periods. To elucidate the underlying biological mechanisms and the clinical and cognitive implications of this neural reorganization.