Magda Caban

Magda Caban
University of Gdansk | UG · Faculty of Chemistry

Doctor hab

About

84
Publications
15,101
Reads
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1,765
Citations
Additional affiliations
June 2012 - present
University of Gdansk
Position
  • Research Assistant

Publications

Publications (84)
Poster
Full-text available
Effects of norfluoxetine on the early embryo development, metamorphosis, survival and growth.
Article
Full-text available
Doxycycline (DOX), an antibiotic commonly used in medicine and veterinary, is frequently detected in natural waterways. Exposition of bacteria to DOX residuals poses a selective pressure leading to a common occurrence of DOX-resistance genetic determinants among microorganisms, including virulent human pathogens. In view of diminishment of the avai...
Article
The production and use of chemicals worldwide, and thus the number of those that can potentially leach into the environment, is constantly increasing. Recent advances in analytical techniques provide the opportunity to detect a wide range of contaminants in water that would not be detected by traditional targeted analysis (TA) methods. These advanc...
Chapter
Pharmaceuticals are chemicals that have been designed to be biologically active at very low doses for therapeutic, prophylactic and preventative purposes. A different approach to monitoring the level of water pollution with pharmaceuticals is passive extraction, where the sampling process is carried out simultaneously with the extraction of analyte...
Article
Studies in recent years have shown that significant amounts of diclofenac (DCF) and its metabolites are present in marine coastal waters. Their continuous flow into the environment may be associated with numerous negative effects on both fauna and flora. Although more and more is known about the effects of pharmaceuticals on marine ecosystems, ther...
Article
The extend of environment pollution by pharmaceuticals is in a stage that required more automatic and integrated solutions. The non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most popular pharmaceutical in the world and emerging pollutants of natural waters. The aim of the paper was to check the correlation of the sales data of selec...
Article
We proposed an innovative and economic method for rapid production of functionalized orange juice (OJ) with excellent nutritional properties, prolonged shelf life, and safe consumption. To reach this goal, we have employed direct current atmospheric pressure glow discharge, generated in contact with a flowing liquid cathode (FLC-dc-APGD) in a highl...
Article
Ionic liquid matrices (ILMs) have been applied for MALDI-MS analysis for more than 20 years. Despite this, there is still insufficient knowledge regarding their properties. In this work, we tested the ionicity of selected ILMs and discussed their impact on the MALDI process. The targets were the following mixtures: CHCA/TEA, FER/TEA, HABA/α-MBA, 2,...
Article
The hazardous and endocrine disturbing compounds (EDCs), present in the wastewaters, notably impair reproduction efficacy of fish and amphibians. Disruption of hormonal homeostasis in humans is also postulated. For this reason, development of an efficient method for purification of wastewaters from these compounds is of the highest environmental co...
Article
In the last decades an increasing number of studies has been published concerning contamination of aquatic ecosystems with pharmaceuticals. Yet, the distribution of these chemical compounds in aquatic environments raises many questions and uncertainties. Data on the presence of selected pharmaceuticals in the same water bodies varies significantly...
Article
Passive sampling techniques are becoming increasingly popular in monitoring of micropollutants. They are especially important to track semipolar and polar contaminants, such as pharmaceuticals. The proper calibration of passive samplers is the key to obtain accurate time-weighted average concentrations (TWAC) of pharmaceuticals in the environment....
Article
Full-text available
Diclofenac (DIC) is one of the most widely consumed drugs in the world, and its presence in the environment as well as potential effects on organisms are the subject of numerous recent scientific works. However, it is becoming clear that the risk posed by pharmaceuticals in the environment needs to be viewed more broadly and their numerous derivati...
Article
The presence of the non-steroidal anti-inflammatory drugs (NSAIDs) are present in the environment, and aquatic and soil organisms are chronically exposed to trace levels of these emerging pollutants. This review presents the current state of knowledge on the metabolic pathways of NSAIDs in organisms at various levels of biological organisation. Mor...
Article
Full-text available
The global problem of the presence of human and veterinary pharmaceuticals in the environment is under investigation. Despite the increase in the knowledge of its sources, fates and impacts, the assessment of risks and the derived prevention actions are limited to single cases. The predicted increasing trend in the usage of pharmaceuticals forces t...
Article
This review starts with a presentation of the theory of kinetic uptake by passive sampling (PS), which is traditionally used to distinguish between integrative and equilibrium samplers. Demonstrated limitations of this model for the passive sampling of pharmaceuticals from water were presented. Most notably, the contribution of the protective membr...
Article
Ionic liquid matrices (ILMs) were introduced almost 20 years ago as alternatives to crystal matrices for MALDI MS analysis. They are protic ionic liquids synthesized by mixing conventional acidic MALDI matrices with an equimolar number of organic amines. They have certain advantageous attributes, such as: i. high homogeneity of the matrix + sample...
Chapter
The analysis of pharmaceutical residues in seawater and sediments is a challenging task. Both mentioned matrices are mixtures of solid and liquid compartments with dissolved gases. Thereby the starting point in monitoring is to choose the proper sampling method to achieve the goal of the research. To perform a whole water analysis, first the water...
Article
The presence of pharmaceuticals in the aquatic environment, both in marine and freshwater reservoirs, is a major concern of global environmental protection. Among the drugs that are most commonly used, NSAIDs tend to dominate. Currently, being aware of the problem caused by drug contamination, it is extremely important to evaluate the scale and the...
Article
The tested facility was a wastewater treatment plant (WWTP) in Swarzewo, where the wastewater treatment takes place in aeration chambers with activated sludge using sequential batch reactors (SBRs). The concentration of the following pharmaceuticals: ibuprofen, paracetamol, flurbiprofen, naproxen, diclofenac, and its metabolites 5OH-diclofenac and...
Article
Full-text available
The study focused on the application of GC in the quantitative analysis of bisphenols and their analogues (12 analytes), and the improvement of solid-phase extraction for the whole water analysis of complex water samples. The role of silylation in the qualitative and quantitative analysis of bisphenols was investigated. Partial degradation occurred...
Article
The study aimed to show the limitations and advantages of the use of stable isotope labeled internal standards (SILISs) for the quantification of small polar compounds (ibuprofen, diclofenac, metoprolol, bisphenol A, 17β-estradiol) in water samples by GC/MS with selected ion monitoring (SIM). The selection of SIM ions shows that for some of the ana...
Article
At the end of August 2019, in Warsaw, the sewage collection system of the Wastewater Treatment Plant malfunctioned. During the subsequent 12 days, over 3.6 million m³ of untreated sewage was introduced from the damaged collector directly into the Vistula River. It is one of the biggest known failures of its kind in the world so far. In this study w...
Article
Rationale Fluorinated derivatization agents allow for the identification and quantification of emerging pollutants with high sensitivity, yet details of their potential applications using electron ionization are lacking. The fluorine atom itself does not effectively participate in electron ionization. Furthermore, limited information exists regardi...
Article
The presence of pharmaceuticals in the marine environment is a growing problem of global importance. Although awareness of the significance of this issue is increasing, many questions related to the ecotoxicology of pharmaceuticals remain unclear. Diclofenac is one of the drugs most commonly detected in the marine environment and its potential toxi...
Article
In this study, biochars (BCs) produced from crops (straw and seeds) were tested for the applicability as additive to soils. The effect on pH, water capacity and cation exchange capacity of soil were tested. The ability for the sorption of pharmaceuticals (beta-blockers, anti-inflammatory drugs, sulfonamides, 17aethinylestradiol, carbamazepine, caff...
Article
Full-text available
The problem of the presence of pharmaceuticals and endocrine disrupting compounds (EDCs) in the environment is closely related to municipal wastewater and in consequence to municipal wastewater treatment plants (MWWTPs) because wastewater is the main way in which these compounds are transferred to the ecosystem. For this reason, the development of...
Article
Full-text available
The work is focused on the verification of a sieving method for the determination of the dependency of bisphenol A concentrations on size fractions of indoor dust. The dust was sampled in houses, an office, a clothing shop and a laboratory. Microscopic photography proves that the dust consisted mostly of fibers. From the seven fractions collected (...
Article
Growing production and consumption of pharmaceuticals is a global problem. Due to insufficient data on the concentration and distribution of pharmaceuticals in the marine environment, there are no appropriate legal regulations concerning their emission. In order to understand all aspects of the fate of pharmaceuticals in the marine environment and...
Article
Passive sampling is an attractive technique for the long‐term monitoring of pharmaceuticals in the water environment. The reliability of the received results depends on the properly performed calibration, namely the determination of analyte sampling rates. This step can be the source of a systematic error, as the sampling rate values are dependent...
Chapter
Full-text available
Industry and the development of civilization implies the penetration of chemical compounds into the environment. Almost all of them are foreign chemicals that disturb the homeostasis of biotic systems. Esters of phthalic acid being the basic compounds that give plasticity to plastic belong to anthropogenic pollution of the environment. Their presen...
Article
In this paper, an analytical method for the simultaneous determination of twenty pharmaceuticals (eight non-steroidal anti-inflammatory drugs, five oestrogenic hormones, two antiepileptic drugs, two β-blockers, and three antidepressants) in soils was developed. The optimal method included ultrasound-assisted extraction, a clean-up step on a silica...
Article
In the presented study, the applicability of four sorbent materials (active carbon, neutral alumina, Primary and Secondary Amines (PSA), and Florosil) applied on top of a polymeric Strata-X column was tested to improve the solid-phase extraction of 15 analytes (pharmaceuticals and estrogens) from water. Deionized water and water fortified by humic...
Article
Interest in the presence of pharmaceutically active compounds in the aquatic environment has been growing for over 20 years, yet very few studies deal with the metabolism of pharmaceuticals in marine organisms. In this study, the bioaccumulation under short-term conditions and metabolism of diclofenac were investigated. Mytilus trossulus was used a...
Article
In this study, an ASE (Accelerated Solvent extraction)-SPE (Solid Phase Extraction)-GC/MS(SIM) method for the simultaneous determination of five non-steroidal anti-inflammatory drugs (NSAIDs: ibuprofen (IBU), paracetamol (PAR), diclofenac (DIC), naproxen (NAP) and ketoprofen (KET)) and three natural estrogens (estrone (E1), 17β-estradiol (E2), estr...
Article
Ionic liquid matrices have been recognized for MALDI application since 2001. However, specific information about the physical and chemical properties, ionicity or proper nomenclature of new matrices has never been presented. The aim of this investigation was to determine the chemical and physical characteristics of ionic matrices using spectroscopi...
Article
The sustainable development of human activities is directly related to the protection of the environment by lowering the anthropogenic stress. Pharmaceuticals – due to their growing consumption (use in medicine, veterinary, animal production, cosmetics) and their incomplete removal in wastewater treatment plants – are classified as a group of new a...
Article
The application of biochar (BC) in various fields of engineering, agriculture and environmental protection demands the task-specific adjustment of the surface characteristics of the carbon material. Polar moieties are those elements which distinguish BC from regular carbon black. The knowledge of polar moieties on the surface of the BC is crucial f...
Article
This work aims at extending the applicability of chiral aqueous biphasic systems (ABS) to enantioseparations by using chiral ionic liquids (CILs) simultaneously as phase forming agents and chiral selectors. After determining the ternary phase diagrams of ABS composed of CILs and salts, these were used to ascertain the CIL structure on the ABS aptit...
Article
One of the most promising tools for the long-term monitoring of pharmaceuticals in the water environment are passive extraction techniques. A necessary step in passive sampling calibration is the determination of the sampling rates (Rs) for target analytes. This process is carried out primarily in laboratory conditions due to practical reasons. How...
Article
Pharmaceutical residues are an emerging environmental problem. It is strongly confirmed that pharmaceuticals are present in soils and environmental waters (surface, marine and even groundwater), and that wastewater treatment plant (WWTP) effluents are the main source of pharmaceuticals in the watershed. The aim of this study was to recognize the sp...
Article
In the presented report, we have described the silylation reaction between the amide group in acetaminophen and a two most popular trifluoroacetamide-based silylation reagents - BSTFA and MSTFA. Both reagents had a amide groups on structures. An investigation was made through the performance of a set of experiments, GC-MS analysis, and a theoretica...
Article
Aiming at outlining new strategies for the valorization of solid pharmaceutical wastes as viable alternatives to incineration, this work proposes the use of ionic liquids-based three phase partitioning (IL-based TPP) systems. Ibuprofen, naproxen and ketoprofen, all belonging to the class of non-steroidal anti-inflammatory drugs (NSAIDs), were adopt...
Article
The widespread use of tetracyclines (TCs) in animal husbandry is associated with their constant penetration into the environment and the threat they might pose to living organisms. While the literature data on the analysis of these substances in such matrices as food, tissues, or wastewater are quite extensive, there are still only a few methods pr...
Chapter
The use of veterinary pharmaceuticals (VPs) is a result of growing animal production. Manure, a great crop fertilizer, contains a significant amount of VPs. The investigation of VPs in manure is prevalent, because of the potential risk for environmental organisms, as well as human health. A re-evaluation of the impact of veterinary pharmaceuticals...
Article
High salinity and a relatively high pH are two factors characterizing the marine water environment, which is one of the main final reservoirs receiving pharmaceutical residues. The same factors have an undeniable impact on the extraction efficiency and kinetics of uptakes of polar analytes from water by sorbent-based passive sampling techniques. Re...
Article
Sulphonamides (SAs) are one of the most commonly used veterinary drugs and therefore their residues are regularly found in the environment. So far scientific attention has mostly been paid to the evaluation of their acute ecotoxicological effects with data on long-term effects for non-target organisms still largely missing. Therefore, the main aim...
Article
Full-text available
Ionic liquids (ILs) are new-generation, non-volatile solvents which are designable, and their structure may be specifically adjusted to the current application needs. Therefore, it is possible to create and apply ILs which efficiently and selectively extract various analytes from different matrices. It has already been examined that ILs may be appl...
Article
The main advantage of alkylimidazolium cation-based ionic liquids (ILs) as phase additives in RP-HPLC is believed to be the suppression of deleterious residual free silanols in chemically modified silica stationary phases. However, up to now, the influence of ILs was usually evaluated having in mind a particular IL salt as one compound, not as a sp...
Article
Full-text available
This paper aims at presenting the possibilities of applying gas chromatography for the determination of pharmaceutical residues in different matrices. Section one of the study underscores the environmental advantages of employing GC for such analyses. Section two presents the innovative methods for determining pharmaceuticals in the environment. Th...
Article
Since humans and ecosystems are continually exposed to a very complex and permanently changing mixture of chemicals, there is increasing concern in the general public about the potential adverse effects they may cause. Among all “emerging pollutants”, pharmaceuticals in particular have raised great environmental concern. For these reasons the aim o...
Article
Pharmaceuticals are commonly found in water collected from wastewater treatment plants, fresh water and saline water. Their presence in water may result in constant accumulation in living organisms, and consequently a negative impact on those organisms. Abiotic samples collected from the Gulf of Gdańsk were already proven to be polluted by several...
Article
In this manuscript, a new dispersive solid-phase extraction (dSPE) method combined with gas chromatography-mass spectrometry and atomic absorption spectrometry was developed for the simultaneous determination of 9 PAHS and chromium, cadmium and lead ions in water samples. For this purpose, non-modified multi-walled carbon nanotubes (MWCNTs) and mod...
Article
Passive sampling is one of the most efficient methods of monitoring pharmaceuticals in environmental water. The reliability of the process relies on a correctly performed calibration experiment and a well-defined sampling rate (Rs) for target analytes. Therefore, in this review the state-of-the-art methods of passive sampler calibration for the mos...
Article
Ionic liquids (ILs) are one of the very promising media for the passive sampling of organic contaminants in water. These compounds offer a wide range of interactions with various analytes and give possibilities to control analyte properties by altering their structures, but most of all, possess a high polarity independent of the water solubility. R...
Article
This work aims at developing a process to valorise pharmaceutical wastes through the recovery of pharmaceutical active compounds. The ibuprofen extraction and isolation from solid pharmaceutical wastes is here used as a case study and an integrated approach comprising the ibuprofen solid-liquid extraction, the removal of the insoluble excipients pr...
Article
The presence of pharmaceutical residues in various environmental compartments is an issue of increasing concern. The widespread occurrence of these compounds in water and soil samples has been demonstrated in a number of analytical studies. However, the data about their concentrations in biota samples is scarce. Moreover, the trophic transfer of ph...
Article
The presence of pharmaceuticals in drinking water, even at very low concentrations, has raised concerns among stakeholders such as drinking-water regulators, governments, water suppliers and the public, with regard to the potential risks to humans. Despite this, the occurrence and the fate of pharmaceuticals in drinking waters of many countries (e....
Article
Full-text available
Anthelmintics are intensively used for veterinary treatment and after being released into the environment can ultimately pose environmental and health hazards. However, to date, there has been very limited information on the concentrations of anthelmintics in the aquatic environment. The monitoring of these compounds in different compartments (wate...
Article
Full-text available
The presence of pharmaceuticals in drinking water has been a subject of concern for the last ten years because many of these pollutants are persistent in such aquatic matrices. Latest studies have shown that they can pose a ecotoxicological risk due to their potential long-term negative effects on living organism, even though the relatively low con...
Article
Full-text available
In recent years, there has been a growing concern in the scientific community regarding the presence of pharmaceuticals in drinking water samples and the potential risks to humans from expo- sure to traces of pharmaceuticals via drinking water. These have been present in these matrices for a long time, but the importance of this fact has only been...
Article
Full-text available
Aqueous biphasic systems (ABS) composed of ionic liquids (ILs) are promising platforms for the extraction and purification of proteins. In this work, a series of alternative and biocompatible ABS composed of cholinium-based ILs and polypropylene glycol were investigated. The respective ternary phase diagrams, tie-lines, tie-line lengths and critica...
Article
Full-text available
Even though the methodology used for the determination of β-blockers and β-agonists in environmental samples is based mainly on solid-phase extraction (SPE) and gas chromatography or liquid chromatography with mass spectrometric detection, the available literature data on the applied SPE procedures is rather sparse. In this paper such comparison is...
Article
Full-text available
Recently, ionic liquids (ILs) have been regarded as an attractive water-immiscible phase in liquid-liquid extraction. Because ILs have a wide range of polarity irrespective of their miscibility with water, the possibility of using them as an effective extraction phase for a broad range of contaminants means they are starting to be of particular int...