Madan Mohan Padhi

Madan Mohan Padhi
Central Council for Research in Ayurvedic Sciences · Department of Medicine

Doctor of Philosophy
As Consultant at ZAC, treating chronic diseases, publishing case studies and planning to publish book on personal exper

About

185
Publications
442,536
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876
Citations
Citations since 2016
42 Research Items
628 Citations
2016201720182019202020212022020406080100120140
2016201720182019202020212022020406080100120140
2016201720182019202020212022020406080100120140
2016201720182019202020212022020406080100120140
Introduction
After retirement from CCRAS, working at Zandu Ayurveda Chikitsalaya, Bhubaneswar and treating chronic and critical diseases and publishing case studies as leads to clinical studies.

Publications

Publications (185)
Article
Detection of de novo variants (DNVs) is critical for studies of disease‐related variation and mutation rates. To accelerate DNV calling, we developed a GPU‐based workflow. We applied our workflow to whole‐genome sequencing data from three parent‐child sequenced cohorts including the Simons Simplex Collection (SSC), Simons Foundation Powering Autism...
Article
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Motivation An abundance of new reference genomes is becoming available through large-scale sequencing efforts. While the reference FASTA for each genome is available, there is currently no automated mechanism to query a specific sequence across all new reference genomes. Results We developed ACES (Analysis of Conservation with an Extensive list of...
Article
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Background: In a developing country like India, which has 10.11% population of >60 years age and a projection of rise of the same by 300% in 2050, health care of elderly is an enormous challenge. The developed world has evolved many models for elderly care, for example, nursing home care, health insurance, etc. Indian Government has also taken mult...
Article
Full-text available
Background Previous research in autism and other neurodevelopmental disorders (NDDs) has indicated an important contribution of protein-coding (coding) de novo variants (DNVs) within specific genes. The role of de novo noncoding variation has been observable as a general increase in genetic burden but has yet to be resolved to individual functional...
Preprint
Full-text available
Motivation: An abundance of new reference genomes are becoming available through large-scale sequencing efforts. While the reference FASTA for each genome is available, there is currently no automated mechanism to query a specific sequence across all new reference genomes. Results: We developed ACES (Analysis of Conservation with Expansive Species)...
Preprint
Full-text available
Detection of de novo variants (DNVs) is critical for studies of disease-related variation and mutation rates. We developed a GPU-based workflow to call DNVs, using 602 trios from the 1000 Genomes Project as a control. We detected 445,711 DNVs, having a bimodal distribution, with peaks at 200 and 2000 DNVs. The excess DNVs are cell line artifacts th...
Article
Full-text available
present era, pharmacological, bio-chemical interventions are not success remedy for Migraine. Ayurveda and other complementary medicine have medication for Migraine. The main aim of the study was to assess the efficacy of therapeutic combination of Shirsooladi vajra ras and Godanti bhasma along with Pathyadi kwatha for management of Migraine on cli...
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Background: Osteoarthritis (OA) is one of the most common forms of arthritis which is caused by the degeneration of joint cartilage. It is often associated with disability and leads to impairment of quality of life. The clinical picture is similar to the disease Sandhigatavata described in Ayurveda (one among the Vatavyadhi) and is characterized by...
Preprint
Full-text available
Previous research in autism and other neurodevelopmental disorders (NDDs) has indicated an important contribution of de novo protein-coding variants within specific genes. The role of de novo noncoding variation has been observable as a general increase in genetic burden but has yet to be resolved to individual functional elements. In this study, w...
Article
Background: In a developing country like India, which has 10.11% population of >60 years age and a projection of rise of the same by 300% in 2050, health care of elderly is an enormous challenge. The developed world has evolved many models for elderly care, for example, nursing home care, health insurance, etc. Indian Government has also taken mul...
Article
Full-text available
Background: Designing health care policies and programmes requires knowledge about health care seeking behavior so that that appropriate intervention can be planned. Health care seeking behavior is a complex outcome of many factors operating at various levels including availability and accessibility of healthcare services. Dependent on these determ...
Book
FOREWORD Non-Communicable Diseases (NCDs) are the group of non-contagious, chronic diseases affecting the individual's quality of life. Cardiovascular disease, cancer, chronic respiratory diseases, and diabetes are the NCDs responsible for the greatest number of deaths worldwide and are the leading cause of death globally killing approximately 36 m...
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Introduction: Sociological literature indicates gender differentiation in both health status and use of health services. It has been observed that women did not complain of any medical problem until it started interfering with their daily activities. Therefore, a cross-sectional community-based survey was conducted in lower socioeconomic group area...
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Background Vatarakta vis-à-vis gout is a common condition in both primary care and specialist practice. Gout is a systemic disease characterized by manifestations of chronic under­lying hyperuricemia, resulting in the deposition of monosodium urate crystals in various tissues. Gout is the most common of the crystal induced arthritis due to disturbe...
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Background Iron deficiency anemia is one of the most prevalent types of nutritional disorder in the world. Its etiology is multifaceted and it generally results when the iron demands of the body are not met by iron absorption. Iron deficiency anemia can be symptomatically compared with Pandu Roga in Ayurveda. Aims and objectives To evaluate the ef...
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Background: Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have a negative effect on health. Obesity is most commonly caused by a combination of excessive food intake, lack of physical activity, and genetic susceptibility. Obesity can be compared with a condition called sthaulya in Ayurveda.
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Introduction The menopausal period comprises about one-third of average women's life. During this period, women are vulnerable to conditions caused by estrogen deficiency from short-term discomfort to long-term health problems. Aim To evaluate the clinical efficacy of Ashokarishta, Ashvagandha Churna and Pravala Pishti in the management of menopau...
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Introduction Udupa Committee Report 1958, Indian Health Policy 1983, National Population Policy 2000, ISM and H Policy 2002, and the National Rural Health Mission are some of the policy recommendations for mainstreaming of Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homoeopathy. Based on these recommendations, the physical mainstreaming for...
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ABSTRACT Background – Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disease which mainly affects the small joints of the hand and feet that may lead to erosion of cartilage and bone associated with irreversible joint damage, joint deformity, systemic complications. The symptoms of Rheumatoid arthritis (RA) can be correlate...
Article
Full-text available
Introduction Sociological literature indicates gender differentiation in both health status and use of health services. It has been observed that women did not complain of any medical problem until it started interfering with their daily activities. Therefore, a cross-sectional community-based survey was conducted in lower socioeconomic group areas...
Article
Full-text available
ABSTRACT Introduction: Osteopenia/osteoporosis is a condition char-acterized by decrease in bone mineral density. It is a major public health problem especially for women in India. The clinical picture of osteopenia/osteoporosis is similar to the condition of Asthidhatukshaya described in Ayurveda which is characterized by the loss of saarata of As...
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Objective: Goraksha or cluster beans are an annual legume found throughout India. It is also extensively cultivated for its pods used as vegetable for its high nutritive value, antidiabetic properties and for the source of guargum. Methods: Macroscopy, microscopy, powder microscopy, histochemical studies and preliminary phytochemical studies on the...
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Objective To establish the pharmacognostic standards for the correct identification and standardization of an important Antidiabetic plant described in Ayurveda. Materials and Methods Standardization was carried out on the leaf and stem of Basella alba L. with the help of the macro-morphological, microscopic, physicochemical and qualitative phytoc...
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AYUSHDHARA, ISSN: 2393-9583 (P)/ 2393-9591 (O) An International Journal of Research in AYUSH and Allied Systems Background: There is re-emergence of the integrative approach to facilitate affordable, safe and equitable health to all. Due to the active initiatives taken up by the Government of India and other stake holders the reach of Ayurveda has...
Book
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It is seen that many scholarly veterinary practitioners of Andhra Pradesh compiled earlier texts and written down their experiences blending the traditional knowledge into the science. Accordingly, the work on the text available in Andhra Pradesh in Telugu, was taken up in this present attempt. It covers nearly 1830 treatments intended to treat 322...
Book
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It is interesting to note that indigenous literatures from ancient India such as Vrikshayurveda have codified numerous techniques and practices of cultivation & harvesting. It is need of the hour to validate these practises and generate tangible evidences so that this knowledge can be mainstreamed into practice. This publication aims to abridge an...
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From historical point of view it is evident that Ayurvedic drugs and procedure based therapies are exceedingly used in alleviating wide range of ocular conditions. Shalakya-tantra-the core engrossing specialty of Ayurveda, deals with management of ocular illness and has been significantly contributing to the eye care. In this study is an attempt ha...
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Objective: To evaluate the clinical usefulness of Rajahpravartini vati in the management of primary dysmenorrhoea (Kashtartava) and changes in the quality of life of the subjects. Study design: A multi-centric prospective single arm observational study. Setting and participants: 359 subjects aged between 16 - 35 years suffering from painful menstru...
Book
Full-text available
This is the second volume of Herbal Wealth of Uttarakhand containing information on families Solanaceae to Poaceae.
Article
The present study is carried out to examine and optimize the method to quantify the presence of Gallic acid, using HPTLC, in ingredient (aqueous extract of Emblica officinalis) as well as in a coded formulation containing extracts of four different herbs in equal quantity developed pharmaceutically in dosage form of capsules. In herbal industry HPT...
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Acacia nilotica Linn. is a common, medium sized tree, belonging to family Leguminosae. It is popularly known as babul, kikar or Indian gum Arabic tree which has been recognized worldwide as a multipurpose tree. It has the ability to synthesize a wide variety of chemical compounds that are used to perform important biological functions and to defend...
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Desmodium gangeticum belongs to family Leguminoceae. It is a versatile plant with many features and considerable prospective. Whole plant is employed as traditional medicine for the treatment of several disorders. D. gangeticum is a traditional Ayurvedic plant used for centuries as an anthelminthic, anti-catarrahal, diuretic, expectorant, astringen...
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Introduction: Ocimum sanctum (OS), known as Holy basil, has been documented to possess neuroprotective, cognition-enhancing and stress relieving effects in animal models. However there is paucity of clinical studies to document these effects. Materials and methods: Effect of OS on parameters related to cognition and stress in humans was evaluated w...
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Three batches of polyherbal tablets were prepared by using the same ingredients as mentioned under Bhaisajya Ratnavali. Each tablet contains Vernonia anthelmintica, Curcuma longa, Piper longum, Mallotus philippinensis, Operculina turpethum, Terminalia chebula, Butea monosperma, and Red ochre. It was prescribed for the treatment of parasitic worms....
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To assess the clinical efficacy of Punarnavaguggulu, Dashmoolaghrita and Kottamchukkadi Taila in the management of Osteoarthritis. Study design: A multi-centric, open level, prospective single arm study. Meterials and Method: 158 subjects of either sex aged between 40 and 75 years with primary osteoarthritis (confirmed by Kellagren Lawrence Radiolo...
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Introduction: This study was carried by the Central Council for Research in Ayurvedic Sciences (CCRAS), Ministry of AYUSH, Govt. of India, with technical support from Indian Council of Medical Research (ICMR), Government of India in selected areas of two districts at Himachal Pradesh for mainstreaming of Ayurvedic interventions of Reproductive and...
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Introduction: A 2-day training program was developed to train Homoeopathy and Ayurveda practitioners to impart HIV/AIDS prevention messages to their clients. The purpose of the study was to evaluate the effectiveness of this training program based on train the trainer modality. Materials and Methods: Ten primary participants were enrolled in each...
Book
Full-text available
This book contains information on Plant wealth of Uttarakhand and the uses of the respective species.