Maciej Karczewski

Maciej Karczewski
Wrocław University of Environmental and Life Sciences · Departament of Mathematics

About

39
Publications
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213
Citations

Publications

Publications (39)
Article
Full-text available
High-flow nasal oxygen (HFNO) is recommended as a first-line treatment in patients with acute hypoxemic respiratory failure due to COVID-19. We assessed the effectiveness of HFNO and predictors of failure and death. The medical records of 200 consecutive adult patients treated with HFNO were analysed. Ninety-two patients (46%) were successfully cur...
Article
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Purpose: The aim of the study was to assess if FINDRISC score was associated with diabetes development after 6 years of observation. Methods: Polish cohort is a part of global PURE study. Hereby analysis presents data from baseline (2007-2010) and 6-year follow-up (2013-2016) and was conducted on 1090 participants (702 women) from urban and rura...
Article
Full-text available
Electrochemical metal processing is a process that generates harmful pollution. An important goal often disregarded by researchers is not only the achievement of the best possible quality of electropolished surface, but also minimising the load of metal ions in the wastewater generated in the process. The conducted experiments on the electropolishi...
Article
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Objective: The main purpose of this research was to establish the relationship between personality traits and internalized stigma in individuals living with severe mental illness. Additionally, the study aimed to identify individual differences that could be used to develop the theoretical socio-cognitive-behavioral equation model of internalized s...
Article
Introduction Changes typical for cerebral small vessel disease (i.a. white matter hyperintensities – WMHs) are often found accidentally in neuroimaging studies. Although asymptomatic, this condition increases the risk of future ischaemic incidents and neurodegenerative disorders. Sleep apnoea is a recognised risk factor for vascular diseases. The a...
Article
This publication presents a comparison of the content of pollutants in groundwater samples taken at 117 measurement points in four regions of Poland during a drought period and in the reference period without drought. Based on the chemical analyses of water, an assessment of the health risk resulting from the use of underground water for consumptio...
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Background: Diabetes mellitus (DM) is one of the greatest challenges for public health worldwide. The aim of the study was the analysis of diabetes development in participants with normoglycemia and Impaired Fasting Glucose (IFG) in 3-year and 6-year follow-up of PURE Poland cohort study. Methods: The analysis was conducted in Polish cohort enro...
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BACKGROUND This study was carried out to evaluate the effects of a long-term high-fat diet on lipids and lipoproteins composition in thoracic duct lymph in pigs. MATERIAL AND METHODS We examined lymph taken from the thoracic duct from 24 female white sharp-ear pigs, divided into 3 experimental groups fed different diets for 12 months: (a) the contr...
Article
Aim of the study: Liver failure is a life-threatening condition which often requires intensive care treatment. It is essential to quickly determine whether there are indications for extracorporeal liver support systems for the patient. The aims of the study were: to assess effectiveness of molecular adsorbent recirculating system (MARS) therapy ba...
Article
Background: Diastolic dysfunction might be associated with increased mortality in severe sepsis and septic shock. In 2016 new American Society of Echocardiography (ASE)/European Association of Cardiovascular Imaging (EACVI) guidelines were published. They simplify our approach to diastolic dysfunction recognition, but they were not validated in cr...
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Introduction In Poland we lack a multidisciplinary and coordinated system of care for people with dementia, which would take the form of an evidence-based pathway and the number of reports on the holistic approach to caring for people living with this diagnosis is very low. Aim of the study The aim of the study was to investigate whether the Meeti...
Article
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Long-term exploitation of industrial electropolishing baths may contribute to the emergence of surface defects and may limit the range of applicable current densities. Due to this, extending the time of use of industrial baths is a major challenge. The application of electrochemical reduction in the process of reduction industrial baths enabled to...
Article
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The study was designed to determine the associations of asymmetric (ADMA) and symmetric (SDMA) dimethylarginines plasma concentrations with all-cause mortality in patients with hematological malignancies. 33 patients with acute myeloid leukemia (AML), 31 patients with non-Hodgkin’s lymphoma (nHL), 32 patients with chronic lymphocytic leukemia (CLL)...
Data
Correlations between DMA and CIT and between DMA/CIT and L-arginine and sVCAM-1 in the study groups (Spearman’s rank correlation test). ns- statistically not relevant (DOCX)
Data
Raw data. This spreadsheet includes all the study individual parameters. (XLSX)
Article
Full-text available
Background: Recent studies, mainly on animal models, have suggested that negatively charged glycosaminoglycans, macrophages, and lymph vessels in the skin interstitium may serve as extrarenal control of sodium balance and blood pressure. The aim of the study was to prove the hypothesis that skin interstitium has a role in the pathogenesis of hyper...
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The main purpose of this article is to present the numerical consequences of selected methods of kernel estimation, using the example of empirical data from a hydrological experiment [1, 2]. In the construction of kernel estimators we used two types of kernels – Gaussian and Epanechnikov – and several methods of selecting the optimal smoothing band...
Article
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In this article we compare and examine the effectiveness of different kernel density estimates for some experimental data. For a given random sample X1, X2, …, Xn we present eight kernel estimators fn of the density function f with the Gaussian kernel and with the kernel given by Epanechnikov [1] using several methods: Silverman’s rule of thumb, th...
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Abstract Introduction HIV infection is associated with an increased risk of cardiovascular disease in connection with atherosclerosis and thromboembolic complications. The pathogenesis of atherosclerosis is still unclear in this group of patients. Studies on pathogenesis of atherosclerosis in the general population emphasize the role of the extrins...
Data
Correlation between TF and TFPI in study group (SG) and control group (CG). (TIF)
Data
Study group, comparison of subgroups with TF<450pg/ml and >450pg/ml. (PDF)
Article
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Introduction: Human immunodeficiency virus (HIV)-associated lipodystrophy syndrome (LS) is defined as a redistribution of adipose tissue, metabolic and endocrine abnormalities, resulting from combined antiretroviral therapy (cART). Aim of this study was to evaluate LS in HIV-infected patients from Lower Silesia, Poland. Material and methods: One hu...
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Introduction: Despite a great progress in antiretroviral therapy (ARV) there are many human immunodeficiency virus (HIV)-infected patients with lipodystrophy syndrome (LS). However, there are still no clearly defined criteria to diagnose dystrophic changes. It would be valuable to introduce a non-invasive and inexpensive method to clinical practice...
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Full-text available
Introduction: More than 1/3 of patients with end-stage renal disease who are in a chronic dialysis program suffer from chronic pain and depression/anxiety. The aim of the study was to determine the impacts of symptoms of depression/anxiety, chronic pain and quality of life (QoL) on 6-year patient survival. Material and methods: Observational study...
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Surgical and endovascular revascularization of ischemic legs in patients with peripheral arterial disease (PAD) can damage the arterial wall (endothelial and smooth muscle cells). Hemostatic factors released during endothelial dysfunction can lead to restenosis. 1. Determination of selected endothelial hemostatic factors in PAD patients and a refer...
Article
Cancer stem cells (CSCs) constitute a sub-population of tumor cells that possess stem cell properties, such as self-renewal and the ability of differentiation. The presence of CSCs is associated with metastatic potential, treatment resistance and poor patient prognosis. Recently, aberrant expression of P-element induced wimpy testis proteins-PIWI (...
Article
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In patients with peripheral artery disease (PAD) a hypercoagulable state and thromboembolic complications occur. Revascularization procedures increase this state, sometimes leading to restenosis. Restenosis following balloon angioplasty (PTA)and stent implantation is ≥ 50% of artery stenosis. To determine the concentration of tissue factor (TF), ti...
Article
Full-text available
Peripheral arterial disease (PAD) is a clinical manifestation of atherosclerosis and mainly refers to elderly patients, having a negative impact on their functionality and quality of life. The findings of previous studies in HIV-infected patients have shown that cardiovascular risk is higher and PAD occurs more frequently than in the general popula...
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Abstract Twenty-six iliac artery segments were divided in two groups: atherosclerotic (A) and nonatherosclerotic (NA). Expression of LYVE-1, VEGF-C, VEGF-D, and CCR7 receptor were studied with immunohistochemistry (IHC) and Western blot (WB). IHC was performed on 26 samples of iliac arteries obtained from deceased 19 organ donors. The samples were...
Article
Full-text available
Introduction. Inflammation plays a central role in the pathophysiology and progression of atherosclerosis, also in patients with peripheral arterial disease (PAD). Revascularization is a risk factor which intensifies this process sometimes leading to newly developed restenosis. Aim. To determine the levels of fibrinogen, C-reactive protein (CRP), i...
Article
Background. Type 2 diabetes (DM2) plays an important role as a risk factor for peripheral arterial disease (PAD). Metabolic abnormalities in DM2, as insulin resistance and hyperglycemia cause overproduction of reactive oxygen species, which via inflammation and endothelial dysfunction lead to atherothrombosis. The injured arterial wall releases hem...
Article
Nogo-B (Reticulon 4B) is considered to be a novel vascular marker, which may have a protective role in injury-induced neointima formation and atherosclerosis. Nogo A/B is found to be crucial for monocyte/macrophage recruitment in acute inflammation and it is expressed in CD68 + macrophages. We hypothesize that macrophage infiltration in atheroscler...
Article
The history of HIV infection has always been associated with patient nutritional problems, initially in the form of wasting syndrome, and since the introduction of highly active antiretroviral therapy such metabolic disorders as lipodystrophy, obesity, insulin resistance, dyslipidemia that are risk factors for cardiovascular diseases have been obse...
Article
To compare the long-term prediction value of the six risk scores in a 7-year follow-up of acute coronary syndrome (ACS) patients. We followed 906 patients diagnosed with ACS for 7 years prospectively. Following risk scores (RS) were calculated: TIMI STEMI, TIMI NSTEMI, GRACE, SIMPLE, ZWOLLE and BANACH. Based on the survival data the prediction valu...
Article
HIV infected patients, especially those treated with antiretroviral (ARV) drugs, show an increased risk and incidence of cardiovascular disease. The aim of this study was to evaluate the progression of subclinical atherosclerosis in the carotid arteries, expressed as the value of carotid intima-media thickness (cIMT) and the amount of atherosclerot...

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Projects

Project (1)
Project
The project foresees the development of an innovative mathematical model that will allow for the determination of the threshold contamination of the baths used in the industrial process of stainless steel electropolishing.