Maciej Bobowicz- M.D., Ph.D.
- Professor (Assistant) at Medical University of Gdansk
Maciej Bobowicz
- M.D., Ph.D.
- Professor (Assistant) at Medical University of Gdansk
EuCanImage Project WP2 Lead; RadioVal Project WP5 Lead; EUCAIM Project T7.2 Co-Lead, Cinderella Project, ADMEDVOICE
About
75
Publications
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Introduction
Current institution
Additional affiliations
May 2015 - present
August 2006 - September 2008
July 2012 - present
Publications
Publications (75)
Background: The development of computer-aided diagnosis systems in breast cancer imaging is exponential. Since 2016, 81 papers have described the automated segmentation of breast lesions in ultrasound images using artificial intelligence. However, only two papers have dealt with complex BI-RADS classifications.
Purpose: This study addresses the au...
Breast cancer is the most frequent female cancer, with a considerable disease burden and high mortality. Early diagnosis with screening mammography might be facilitated by automated systems supported by deep learning artificial intelligence. We propose a model based on a weakly supervised Clustering-constrained Attention Multiple Instance Learning...
Computer-aided detection systems based on deep learning have shown good performance in breast cancer detection. However, high-density breasts show poorer detection performance since dense tissues can mask or even simulate masses. Therefore, the sensitivity of mammography for breast cancer detection can be reduced by more than 20% in dense breasts....
Artificial intelligence (AI) is revolutionizing the field of medical imaging, holding the potential to shift medicine from a reactive “sick-care” approach to a proactive focus on healthcare and prevention. The successful development of AI in this domain relies on access to large, comprehensive, and standardized real-world datasets that accurately r...
Image quality assessment of magnetic resonance imaging (MRI) data is an important factor not only for conventional diagnosis and protocol optimization but also for fairness, trustworthiness, and robustness of artificial intelligence (AI) applications, especially on large heterogeneous datasets. Information on image quality in multi-centric studies...
Artificial Intelligence (AI) research in breast cancer Magnetic Resonance Imaging (MRI) faces challenges due to limited expert-labeled segmentations. To address this, we present a multicenter dataset of 1506 pre-treatment T1-weighted dynamic contrast-enhanced MRI cases, including expert annotations of primary tumors and non-mass-enhanced regions. T...
The nnU-Net framework has played a crucial role in medical image segmentation and has become the gold standard in multitudes of applications targeting different diseases, organs, and modalities. However, so far it has been used primarily in a centralized approach where the data collected from hospitals are stored in one center and used to train the...
Artificial intelligence (AI) is a powerful technology with the potential to disrupt cancer detection, diagnosis and treatment. However, the development of new AI algorithms requires access to large and complex real-world datasets. Although such datasets are constantly being generated, access to them is limited by data fragmentation across numerous...
Despite major advances in artificial intelligence (AI) research for healthcare, the deployment and adoption of AI technologies remain limited in clinical practice. This paper describes the FUTURE-AI framework, which provides guidance for the development and deployment of trustworthy AI tools in healthcare. The FUTURE-AI Consortium was founded in 20...
Good practices in artificial intelligence (AI) model validation are key for achieving trustworthy AI. Within the cancer imaging domain, attracting the attention of clinical and technical AI enthusiasts, this work discusses current gaps in AI validation strategies, examining existing practices that are common or variable across technical groups (TGs...
Background and Objectives: Surgical treatment for obesity is becoming increasingly popular. Surgeons have been trying to find a simple way to predict the type of surgical intervention that is best for a specific patient. This study aimed to determine the patient- and surgeon-related factors that affect weight loss after laparoscopic sleeve gastrect...
Current research in breast cancer Magnetic Resonance Imaging (MRI), especially with Artificial Intelligence (AI), faces challenges due to the lack of expert segmentations. To address this, we introduce the MAMA-MIA dataset, comprising 1506 multi-center dynamic contrast-enhanced MRI cases with expert segmentations of primary tumors and non-mass enha...
TPS621
Background: Breast cancer treatments often pose challenges in balancing efficacy with quality of life. The CINDERELLA Project pioneers an artificial intelligence (AI)-driven approach (CINDERELLA APP) for shared decision-making process, aiming to harmonise locoregional therapeutic interventions with breast cancer patients' expectations about...
Fluorescence is used in various surgical fields to detect tissue ischemia. However, its use in obesity surgery is still limited. This study aims to investigate whether fluorescence can help detect ischemia during metabolic and bariatric surgery and assess its effectiveness in reducing complications. The main objective was to determine the percentag...
Background
An unprecedented amount of personal health data, with the potential to revolutionise precision medicine, is generated at healthcare institutions worldwide. The exploitation of such data using artificial intelligence relies on the ability to combine heterogeneous, multicentric, multimodal and multiparametric data, as well as thoughtful re...
Purpose
This review aims to explore and summarise current knowledge of indocyanine green (ICG) fluorescence application in metabolic and bariatric surgery (MBS) and assess its potential in improving patient safety.
Methods
The review was prepared according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommend...
To achieve clinical impact in daily oncological practice, emerging AI-based cancer imaging research needs to have clearly defined medical focus, AI methods, and outcomes to be estimated. AI-supported cancer imaging should predict major relevant clinical endpoints, aiming to extract associations and draw inferences in a fair, robust, and trustworthy...
Computer-aided detection systems based on deep learning have shown good performance in breast cancer detection. However, high-density breasts show poorer detection performance since dense tissues can mask or even simulate masses. Therefore, the sensitivity of mammography for breast cancer detection can be reduced by more than 20% in dense breasts....
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Abstract Laparoscopic appendectomy (LA) for treatment of acute appendicitis has gained acceptance with its considerable benefits over open appendectomy. LA, however, can involve some adverse outcomes: morbidity, prolonged length of hospital stay (LOS) and hospital readmission. Identification of predictive factors may help to identify and tailor tre...
Quality of life (QoL), is defined by WHO, as an elaborate concept which focuses on a person’s physical health, psychological state, personal beliefs, social relations and the way they interact with their regular environment. Assessing QoL using validated questionnaires provides essential information regarding the efficacy of our care or the treatme...
Background: In general, the three main options for stump closure in laparoscopic appendectomy are clips, endoscopic staplers and endoloops. However, there is no gold standard, especially regarding complicated acute appendicitis which is generally associated with worse outcomes.
Objectives: We aimed to assess the outcomes of different stump closure...
Introduction: According to meta-analyses laparoscopic appendectomy is associated with many bene ts. However, in comparison to open surgery an increased rate of intraabdominal abscesses (IAA) has been reported. Identi cation of predictive factors for this complication may help to identify patients with higher risk of IAA.
Aim: To identify potential...
Acute appendicitis (AA) is the most common surgical emergency and can occur at any age. Nearly all of the studies comparing outcomes of appendectomy between younger and older patients set cut-off point at 65 years. In this multicenter observational study, we aimed to compare laparoscopic appendectomy for AA in various groups of patients with partic...
Breast cancer has high metastatic potential with distant metastases involving mainly lungs, liver and bones. Less frequently it gives distant spread to other organs. Herein we would like to present a very rare case of an acute cholecystitis which turned out to be a metastatic breast cancer in previously healthy woman. A female patient, 64-years old...
The role of adjuvant chemotherapy in stage T2-T3N0 colon cancer (CC) is controversial and there are currently no reliable factors allowing for individual selection of patients with high risk of relapse for such therapy. We searched for microRNA-based signature with prognostic significance in this group. We assessed by qRT-PCR expression of 754 micr...
Colorectal carcinoma (CRC) is one of the leading causes of cancer-related deaths worldwide. Alterations in keratin expression, including keratin 7 (K7), are frequent findings in multiple cancers, and they constitute a prognostic factor. The aim of our study was to evaluate the prognostic significance of K7 in the primary tumour and lymph node metas...
More than 1 million inguinal hernia repairs are performed in Europe and the US annually. Although antibiotic prophylaxis is not required in clean, elective procedures, the routine use of implants (90% of inguinal hernia repairs are performed with mesh) makes the topic controversial. The European Hernia Society does not recommend routine antibiotic...
Introduction:
Absent today is a simple numerical system of outcomes assessment that recognizes that bariatric surgery is metabolic surgery and incorporates weight loss, hypertension control, and type 2 diabetes control.
Aim:
To introduce a simple, new Numerical Scale to Assess the Outcomes of Metabolic Surgery (NOMS).
Material and methods:
For...
We describe an extracorporeal staple technique used to treat severe colostomy stenosis under analgo-sedation, thus avoiding relaparotomy. The surgery is performed under short-term sedation. The orifice of the stoma is widened and overgrowing skin is excised. The volume and diameter of the stoma are assessed. The anvil of a circular stapler device i...
Pleural empyema is the most serious, life-threatening postoperative complication of pneumonectomy, observed after 1-12% of all pneumonectomies, with bronchopleural fistula being its main cause.
The aim of this publication is to present early outcomes of minimally invasive surgical management of pleural empyema. Patients were subjected to a single,...
Introduction:
Laparoscopic sleeve gastrectomy (LSG) and laparoscopic adjustable gastric banding (LAGB) are acceptable options for primary bariatric procedures in patients with body mass index (BMI) 35-55 kg/m(2).
Aim:
The aim of this study is to compare the effects of these two bariatric procedures 6, 12 and 24 months after surgery.
Material an...
Purpose
Preoperative nutrition is beneficial for malnourished cancer patients. Yet, there is little evidence whether or not it should be given to nonmalnourished patients. The aim of this study was to assess the need to introduce preoperative nutritional support in patients without malnutrition at qualification for surgery.
Methods
This was a pros...
Hemorrhoidal disease is one of the commonest anorectal disorders worldwide. Stapled hemorrhoidopexy (SH) is a treatment modality associated with low postoperative pain and early mobilization.
To assess long-term outcomes after SH.
All 326 patients who underwent SH in 1999-2003 were invited by mail to participate. For each patient we analyzed their...
Patients with gastric tumors usually present with symptoms of discomfort or pain in the epigastrium, regurgitations, nausea, vomiting or melena. Treatment options include open and laparoscopic total or partial gastrectomy and recently endoscopic mucosal resection. A case of successful endoscopic submucosal dissection is described with the unusual p...
With the introduction of new surgical equipment, there is always the need for new, more advanced training. The authors try to answer whether the use of the newest generation tools has an impact on achieving better results in single incision laparoscopic surgery (SILS) technique during the exercises in the surgical skills laboratory.
There were 51 p...
Unlabelled:
Over the last decade, gastric cancer treatment has changed from extensive multiorgan resections towards less invasive approaches with limited resections and a more selective lymphadenectomy. Despite all available trials, the conclusions on the extent of necessary resections still remain debatable. The aim of the study was to assess the...
For many years, laparoscopic cholecystectomy remains the method of choice for both the treatment of symptomatic cholelithiasis, and chronic and acute cholecystitis (1). The experience of the surgeon grows with each laparoscopic procedure, which enables to operate in case of difficult anatomical conditions and associated anatomical variants. The aim...
Introduction: Gallbladder cancer (GBC) is the fifth most common cancer involving the gastrointestinal tract. The aim of our study was to determinate the proper extent of surgical treatment in patients with GBC according to extent of the tumor (T) and to determine the exact common bile duct management and extent of hepatectomy and lymph node resecti...
We describe a case of cardiac tamponade caused by ProTacks Autosuture used for mesh fixation during a laparoscopic Nissen operation with giant paraesophageal hernia repair. Perforations of the posterior descendent artery and epicardial vein of the right ventricle were caused by ProTacks used for Parietex Composite Mesh fixation. Protruding ProTacks...
In recent years, multiple studies have proved laparoscopic total mesorectal excision (TME) to be as safe and as effective in rectal cancer treatment as open surgery, with the undeniable benefit of perioperative trauma reduction. Decreasing the number of incisions and performing single-port surgery could have further reduced the trauma. A new access...
Laparoscopic adjustable gastric banding (LAGB) is considered to be a very effective minimally invasive procedure for treating morbidly obese patients. Nevertheless, there are numerous complications that a good surgeon should be aware of. Most of them have been widely presented in the literature.
In this study we would like to focus on the rare but...
Surgical emergency procedures remain the most unpredictable operations. In this paper we describe a case of a 44-years-old male patient with sudden peptic ulcer perforation a few days before planned esophagectomy with simultaneous reconstruction for suspected c neoplastic stricture of the lower oesophagus. Emergency laparotomy revealed large perfor...
In oncological patients with upper gastrointestinal tract tumours, dysphagia and cachexy necessitate gastrostomy or jejunostomy as the only options of enteral access for long-term feeding. In this article the authors describe a modified technique of laparoscopic feeding jejunostomy applied during the staging laparoscopy. A 48-year-old male patient...
The aim of this study was to develop a less-invasive transanal endoscopic microsurgery (TEM) operative technique that could be applied in severely ill patients. Modified technique of TEM operation with use of the TriPort Access System in place of the operative rectoscope was designed. Harmonic scalpel and regular laparoscopic instruments were used....
Natural orifice transluminal endoscopic surgery (NOTES) is a natural consequence of evolution in minimally invasive surgery It allows one to reduce surgical trauma and the number of complications and to improve cosmetic outcomes. It also shortens the patient's recovery time. So far there have been only nine NOTES procedures performed in Poland and...
Introduction: Laparoscopic sleeve gastrectomy (LSG) as a stand-alone or a first step in the biliopancreatic diversion - duodenal switch (BPD-DS) procedure is frequently the surgery of choice for the 21(st) century's epidemic of morbid obesity To date, LSG as a relatively new method has few complications reported and analysed. Aim: The article descr...
Laparoscopic adjustable gastric banding (LAGB) remains the most popular surgical modality for obesity management in Europe. The aim of this publication is to present a 5-year experience in obesity treatment with LAGB operation with the assessment of outcomes, frequency of complications, and their management. Management of the band-related complicat...
The aim of this study was to assess outcomes of laparoscopic sleeve gastrectomy (LSG) as a stand-alone bariatric operation according to the Bariatric Analysis and Reporting Outcome System (BAROS).
Out of 112 patients included and operated on initially, 84 patients (F/M, 63:21) were followed up for 14-56 months (mean 22 ± 6.75). Patients lost to fol...
The aim of this review was to assess the results of published experience with bariatric SILS surgery, with a particular focus on treatment feasibility and safety. An EMBASE and MEDLINE database search was performed identifying 13 articles totalling 87 patients in the laparoscopic adjustable gastric banding (LAGB) group, 10 patients in the laparosco...
Aim: To present a novel technique of a laparo-endoscopic single site (LESS) distal pancreatic resection via the umbilicus with use of the QuadPort (TM) Access System. Material and methods: The technique of distal pancreatic resection through a 30 mm longitudinal incision in the umbilicus is described. Medial to lateral approach of pancreas preparat...
Despite their current limitations, metabolic surgery and natural orifice transluminal endoscopic surgery (NOTES), set new horizons. In this article, the first three cases of adjustable gastric banding (AGB) through transvaginal access in obese women are described.
In the General and Vascular Surgery Department, Ceynowa Hospital, Poland, three cases...
Chronic obstructive pulmonary disease (COPD) is one of the most common chronic diseases and the fourth cause of death in the world. Its advanced forms (severe — in case of FEV 1 indicator below 50% of the norm and very severe — below 30%) usually lead to respiratory disability and premature death. The prognoses of those suffering from severe forms...
Laparo-endoscopic single-site surgery (LESS) is a step toward an even less invasive surgical procedure. LESS is being performed for a wide variety of procedures. Use of a natural scar, the umbilicus, for introduction of the trocar improves the cosmetic effect. We describe LESS right hemicolectomy. Hospital stay was 3 days and no postoperative compl...
Background and aim. Lung cancer is one of the most common tumours and the cause of cancer-related deaths in European countries. In the past few years, a significant morbidity of chronic obstructive pulmo-nary disease (COPD) has been noticed in this group of patients. Cigarette smoking is the strongest risk factor for both conditions. The palliative...
Background. The aim of the study was to evaluate the frequency of coexistance of lung cancer and chronic obstructive pulmonary disease. Material and methods. Fifty one patients (13 women and 38 men, aged from 40 to 80 years, range: 63 years) with diagnosed advanced lung cancer (stage IIIB and IV) were included into the study. Results. The chronic o...
Questions
Question (1)
During the last 3 years I have experienced 3 occurences of the stenosis in the colo-rectal end-to-end anastomisis following laparoscopic sigmoid or TME resections for sigmoid/upper rectal cancer. In two cases the stricture occluded the bowel completely. These two patients underwent stenting first. It failled due to the overgrow of the fibrotic tissue in the next 2-4 months leading to the complete obstruction. Thus why, they required emergency laparotomy with excision of the stenosed portion of the bowel with end colostomy. Then, we recreated the continuity of the bowel with protective ileostomy (to make sure they do not go into obstruction). Around a half a year later we closed the ileostomy.
Now I diagnosed the stenosis in the third patient (the lumen of stenosis of 8 mm) and just wonder what other options are, as I do not want to go the same route again.
