Mabrouk Teguiche

Université 8 mai 1945 - Guelma · Department of Material Science

A suitable methodology of synthesis of coumarin derivatives by Pechmann reaction over heterogeneous solid acid catalysts in a free solvent media under microwave irradiation is described. Resorcinol, phenol and ethyl acetoacetate were selected as model reactants in the Pechmann condensation. The catalytic activity of several materials—Amberlyst-15,...

Dimethyl acetylenedicarboxylate (DMAD) undergoes efficient Huisgen 1,3-dipolar cycloaddition reaction with various X-substituted aryl azides (X = 2C1, 3C1, 2COOCH3, 4COOCH3), applying two different conditions, under conventional stirring at room temperature or under microwave irradiation, to afford the corresponding 1,4,5-trisubstituted 1,2,3-triaz...

Azomethine ylide, prepared from quinazolinium salt, undergoes 1,3-dipolar cycloaddition with alkyne dipolarophiles to produce substituted pyrroles. In fact, when alkene dipolarophiles were introduced, a novel compound i.e., substituted pyrrolo[1,2-a]quinazolinones have resulted from this work.

Grapes and wines are now known to constitute a rich source of phenolics such as stilbenes and flavonoids. These compounds have been shown to have cancer chemopreventive activity and potential beneficial effects on cardiovascular diseases thanks to their antioxidant and antiplatelet properties. However, because little is known about African wines an...

In protic solvents, 2-azidobenzaldehyde undergoes base-catalysed condensation with cyanocarbanions to yield tetrazolo[1,5-a]quinolines 5a-g, whereas in aprotic media 1,2,3-triazolo[1,5-a]quinazolines 6a-f are formed. Triazoloquinazolines 9 a-g are also obtained from 2'-azidoacetophenone and from 2-azidobenzonitrile, whereas with 2-azidobenzoyl chlo...

The title compounds were prepared by the action of the diethyl 1,3-acetonedicarboxylate anion on ortho-substituted aryl azides. The anion was formed using either a sodium alkoxide in the appropriate alcohol or by an ion-exchange resin [Amberlite IRA-400(OH)].

Thesis (Ph. D.)--University of Salford, 1991.