Ma. Angélica Michea

• Professor at University of Chile

Ferroptosis is implicated in the pathogenesis of numerous chronic-inflammatory diseases, yet its association with progressive periodontitis remains unexplored. To investigate the involvement and significance of ferroptosis in periodontitis progression, we assessed sixteen periodontitis-diagnosed patients. Disease progression was clinically monitore...

Aging is a gradual and adaptive process that entails a series of changes, leading to reduced functional and physiological capacity. Each elderly person presents heterogeneous health conditions that must be considered by the interdisciplinary team responsible for their functional maintenance and overall health. This descriptive, cross-sectional stud...

Dental caries is a significant global public health challenge, particularly among children and adolescents. It affects individuals' quality of life and can lead to various adverse outcomes, including pain, infection, and impaired school performance. Fluoride has been widely recognized as a key component in oral health improvement programs due to it...

Background and objective: There is no clear understanding of molecular events occurring in the periodontal microenvironment during clinical disease progression. Our aim was to explore qualitative and quantitative differences in gingival crevicular fluid (GCF) protein profiles from patients diagnosed with periodontitis between non-progressive and p...

During orthodontic treatment, diverse cytokines, enzymes, and osteolytic mediators produced within the teeth surrounding periodontal tissues determine the rate of alveolar bone remodeling and consequent teeth movement. In patients with teeth presenting reduced periodontal support, periodontal stability should be ensured during orthodontic treatment...

Due to the fact that people live longer, population ageing has occurred, thus manifesting chronic diseases that have a multidimensional implication. The different diseases that a person may present can cause frailty and involve the oral health of the elderly. Oral health is related to general health as there is a link that is being analysed today....

The ageing population has increased globally, leading to the prevalence of geriatric syndromes, including frailty. Frailty is associated with multiple physiological system impairments, increased vulnerability to stressors, and functional disabilities. Dental problems are common among older adults and can contribute to frailty by causing chewing dif...

La alta prevalencia e impacto económico y social de las enfermedades orales constituye un importante desafío en el campo de la salud pública a nivel mundial. En Chile, la alta carga de enfermedades orales sumadas a las marcadas inequidades en salud bucodental, justifican la necesidad de generación de conocimiento útil para enfrentar este grave prob...

In patients with periodontitis, pathologic tooth migration is a consequence of loss of periodontal support. The following case report addresses the periodontal and orthodontic treatment of a patient with periodontitis and pathologic tooth migration. The protocol used was the protocol of the Orthodontics and Periodontics Unit of the Faculty of Denti...

This case report shows a patient attended in the Postgraduate Periodontics Program at the Faculty of Dentistry of the University of Chile with a diagnosis of Gingival Enlargement influenced by cyclosporine and nifedipine. The therapeutic approach considered the systemic phase, the hygienic phase with the non-surgical periodontal treatment to achiev...

Cuando se instaló odontogeriatría en el currículo de pre-grado, dependiente del Departamento de Odontología Conservadora de la Facultad de Odontología, Universidad de Chile, se implementó un cambio en el modelo tradicional de educación clínica, abandonando los requisitos numéricos de procedimientos solicitados a los estudiantes por cada disciplina,...

En la actualidad existe consenso en que el daño de los tejidos de soporte dentario que se produce durante la periodontitis es un proceso complejo en el cual la presencia de los patógenos periodontales es necesaria, pero no suficiente, para explicar en su totalidad la extensión y severidad de dicho daño. Asimismo, la destrucción del tejido de soport...