Ma. Luisa De Asis Enriquez

De La Salle University | DLSU · Center for Natural Sciences and Environmental Research (CENSER)

Background: Colorectal cancer (CRC) ranks third in terms of incidence and second in mortality worldwide. In CRC, the silencing of mismatch repair genes, including the mutL homolog 1 (hMLH1) has been linked to microsatellite instability (MSI), the lengthening or shortening of microsatellite repeats. Very limited data have been presented so far on t...

BACKGROUND Commercial strawberry production in the Philippines is done by small-holder farmers in La Trinidad, Benguet, where the climate is conducive for optimal growth of this temperate crop. However, these farmers are not cognizant of the importance of proper cultivar identification, particularly during runner propagation, distribution, and tran...

This paper characterizes the high incidence of breast cancer in Bacolod City, Philippines. The methods of research involved (1) an epidemiological study; (2) a determination study on the environmental factors that cause breast cancer; and (3) a breast cancer behavioral study. A statistical analysis of the personal demography profile found significa...

Introduction: The efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in EGFR mutation-positive non-small-cell lung cancer (NSCLC) patients necessitates accurate, timely testing. Although EGFR mutation testing has been adopted by many laboratories in Asia, data are lacking on the proportion of NSCLC patients tested in ea...

Chromosome analysis was performed on thirty-three (33) primary colorectal tumors derived from patients (18 males and 15 females) diagnosed with colorectal adenocarcinoma at st. Luke's Medical Center. using GtG-banding technique, structural as well as numerical abnormalities were seen. two samples have normal karyotype, 26 have numerical abnormaliti...

A 6-year-old girl presented with disseminated polymorphous skin lesions of several months' duration, joint pains, recurrent fever, anemia, and inguinal adenopathy. Subsequent evaluation of skin, lymph node, and bone marrow morphology showed infiltration of atypical lymphocytic cells. Immunohistochemical and flow cytometric analysis showed findings...

Objective: To detect and characterize retinoblastoma susceptibility gene (RB1) mutations in tumor samples collected from Filipino patients with retinoblastoma. Methods: Six tumor samples were obtained from Filipino patients diagnosed with retinoblastoma. DNA was extracted from the tumor samples and exons 13-21 of the RB1 gene were amplified by poly...