M. Rousselet

M. Rousselet
Centre Hospitalier Universitaire de Nantes | CHU Nantes · Pôle universitaire d'addictologie et de psychiatrie

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65
Publications
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281
Citations

Publications

Publications (65)
Article
Full-text available
Background: The French national drug regulatory authority stated, in 2017, that a secured prescription pad must be used for zolpidem prescriptions. This study aimed to evaluate the evolution of the problematic consumption of zolpidem at the individual level since the new regulation. Methods: Two nationwide populations of at-risk users of zolpide...
Article
Background: In recent years, zolpidem has been the subject of numerous reports of misuse, abuse and dependence. In view of these risks, the French drug agency decreed the implementation of secure prescription pads in April, 2017. The objective of this study was to characterize the impact of this regulatory change on the patterns of zolpidem use....
Article
The article describes the diverse modalities of inpatient care for anorexia nervosa in France (11 specialized centers). The impact of this diversity on patient outcome will be studied as a result of this work.
Article
Résumé Le recours à l’hospitalisation dans l’anorexie mentale se fait dans des situations extrêmes dont les critères sont codifiés internationalement et nationalement. Néanmoins il existe sur le terrain de multiples modalités d’application de ces principes. Aucun travail n’a été réalisé afin d’évaluer si les différentes modalités de prise en charge...
Article
Full-text available
Objective Anorexia nervosa (AN) is a complex disease in which obsessive thoughts about body image, shape, or weight are expressed. The intensity of these concerns varies among individuals, and only a few studies have focused on their impact on patients’ clinical course when patients are treated on an outpatient basis. Our study aimed to determine w...
Article
Full-text available
PurposeThe cognitive profiles of patients suffering from anorexia nervosa (AN) are currently explored as potential facilitating and/or maintenance factors. Specific data in restrictive AN (AN-R) remain contradictory. This study focused on women with AN-R to evaluate their cognitive functions to develop a more specific cognitive remediation program....
Article
Introduction Ces dernières années, le zolpidem a été le médicament hypnotique le plus prescrit en France et a également fait l’objet de multiples rapports de mésusage, d’abus et de dépendance. Devant ces risques, les médecins ont été informés en janvier 2017 qu’à partir d’avril 2017 la prescription du zolpidem devait obligatoirement être réalisée s...
Article
Full-text available
Background Sickle cell disease (SCD) induces chronic haemolytic anaemia and intermittent vaso-occlusion that results in tissue ischaemia causing acute, severe pain episodes that can lead to frequent hospitalizations. These consequences can have repercussions on family, social, school and/or professional life. Here, we present some of the results of...
Article
Introduction Ces dernières années, le zolpidem a été le médicament hypnotique le plus prescrit en France et a également fait l’objet de multiples rapports de mésusage, d’abus et de dépendance. Devant ces risques, les médecins ont été informés en janvier 2017 qu’à partir d’avril 2017 la prescription du zolpidem devait obligatoirement être réalisée s...
Article
Introduction Les antihistaminiques (antiH1) de première génération disponibles sans prescription sont approuvés dans de nombreuses indications telles que l’insomnie, la toux, l’écoulement nasal, la cinétose. Leurs propriétés pharmacologiques antihistaminiques et atropiniques en font des substances susceptibles d’être mésusées, c’est-à-dire avec une...
Article
Introduction Le zolpidem est un des médicaments hypnotiques les plus prescrits en France et son potentiel d’abus et de dépendance a été montré dans plusieurs études. En janvier 2017, une information a été communiquée aux médecins sur l’obligation à partir d’avril 2017 de prescription du zolpidem sur ordonnance sécurisée. L’étude ZORRO (ZOlpidem et...
Article
Full-text available
Purpose: Benzodiazepines (BZDs) and related drugs (Z-drugs) are mainly taken chronically, and older people are much more likely to take them on a chronic basis despite recommendations. Withdrawal symptoms could be an obstacle to stopping BZD/Z-drug administration. The main objective of this study is to estimate the prevalence of withdrawal symptom...
Article
Aim: In recent years, zolpidem has been the subject of numerous reports of misuse, abuse and dependence. In view of these risks, the French drug agency (ANSM) decreed in April, 2017 the implementation of secure prescription pads. The objective of this study was to evaluate the impact of this regulatory measure on the prescription of zolpidem and o...
Article
Benzodiazepines and related drugs (BZD/Z) are used longer than recommended in the elderly population. However, to date, very few attempts have been made to evaluate dependence on BDZ/Z among the elderly population. We conducted a national multicentric observational prospective study aimed at evaluating the prevalence of and risk factors for depende...
Article
Full-text available
The concept of “food addiction” (FA) has aroused much focus because of evidence for similarities between overeating and substance use disorders (SUDs). However, few studies have explored this concept among the broad spectrum of eating disorders (ED), especially in anorexia nervosa (AN). This study aimed to assess FA prevalence in ED female patients...
Article
Full-text available
Objectives: Benzodiazepines and non-benzodiazepine hypnotics (or Z-drugs) (BZD/Z) are widely prescribed for older patients despite major side effects and risks when chronically used. The patient's understanding of the treatment is one of the keys to good adherence. The purpose of the study was to assess the knowledge of BZD/Z treatment among older...
Article
Full-text available
Our objective was to quantify the impact on the use of zolpidem of the obligation implemented in France in 2017 to use secure prescription pads to prescribe it. We conducted a cohort study within the French SNDS healthcare database. Patients aged over 18 years of age were considered for inclusion. The number of prevalent users and incident episodes...
Article
Full-text available
Background Few studies have examined the consumption trajectories of inmates after entry to prison. The aim of this study was to assess the changes in the consumption of psychoactive substance between the period before detention and during incarceration and to characterize the profiles of prisoners with similar consumption trajectories during incar...
Article
Contexte : Les troubles périnéosphinctériens (TPS) survenant chez les patients souffrant de trouble du comportement alimentaire (TCA) sont des complications sous-abord ées dans la littérature. Le but de cette revue de la littérature était de faire le point sur l’état des connaissances actuelles pour aider le clinicien prenant en charge les TPS à le...
Article
Full-text available
Introduction In recent years, data collected by the French Addictovigilance Network have shown the potential for abuse and addiction associated with zolpidem (the most sold hypnotic drug in France). Since 10 April 2017, new regulations have come into force that require zolpidem to be prescribed on special secure prescription pads, in order to reduc...
Article
Full-text available
Background Many studies were conducted to assess the benefit/risk ratio of EMONO (Equimolar Mixture of Oxygen and Nitrous Oxide) in France before it was authorized for use outside the hospital setting in 2009. The main objective of this project is to evaluate the effects sought and felt by children when EMONO is used in paediatric dentistry. The se...
Article
Background: Many studies were conducted to assess the benefit/risk of equimolar mixture of oxygen and nitrous oxide (EMONO), but evaluating the appetite associated to its use is now getting very little attention in the literature. The purpose of this study was to investigate the effects present, felt, and sought during care by the child related wit...
Article
Introduction La consommation de substances psychoactives en prison existe même si elle est réglementairement interdite. Plusieurs études effectuées en France dans des populations carcérales ont évalué la prévalence de cette consommation. Cependant, l’évolution des consommations et des modalités de consommation entre le moment de l’entrée en établis...
Article
Introduction Les poppers, autrefois utilisés en médecine pour leurs propriétés vasodilatatrices dans l’angor, font aujourd’hui l’objet d’abus. Après avoir été réglementée, leur vente est aujourd’hui libre. Utilisés à des fins sexuelles ou récréatives, on assiste aujourd’hui à une explosion de l’utilisation des poppers chez les jeunes, notamment pou...
Article
Full-text available
Objectives Addictions are not restricted to substance-use disorders, and it is now widely recognized that they also include behavioral addictions. Certain individuals with eating disorders also experiment their disorder as an addiction. The objective was to identify typologies of patients presenting with various behavioral addictions or eating diso...
Data
Graphic representations of the latent trajectories obtained for the 2 ASRS dimensions after the Growth Mixture Models analysis. (DOCX)
Data
Graphic representations of the latent trajectories obtained for the 3 damage scores after the Growth Mixture Models analysis. (DOCX)
Data
Graphic representations of the latent trajectories obtained for the 4 UPPS-P dimensions after the Growth Mixture Models analysis. (DOCX)
Data
Graphic representations of the latent trajectories obtained for the 3 character dimensions of the TCI after the Growth Mixture Models analysis. (DOCX)
Article
Le terme de « Food addiction », ou addiction à l’alimentation (AA), a été introduit en 1956 par Randolph. Il repose sur l’idée que certains aliments pourraient avoir un potentiel addictif et que la suralimentation pourrait constituer une forme de comportement addictif. Pour diagnostiquer une AA, il est donc tentant d’appliquer des critères déjà exi...
Article
Plusieurs auteurs ont remarqué la fréquente association entre une pratique sportive excessive et la consommation de substances psychoactives ou la présence d’un trouble du comportement alimentaire. Cependant, aucune étude ne s’est intéressée à comparer ces deux types de patients vis-à-vis de leur pratique sportive. L’objectif de cette étude était d...
Article
Introduction L’anorexie mentale restrictive (AMR) concerne, en France, à peu près 1,5 % de la population féminine, entre 15 à 35 ans. L’AMR est fréquemment associée à des comorbidités psychiatriques et présente un taux élevé de décès. La remédiation cognitive est une technique thérapeutique prometteuse en cours d’évaluation [1]. L’objectif de cette...
Article
History of intensive sports practice: comparison between patients with substance use disorders and eating disorders Several authors have noted the frequent association between excessive sport and the consumption of psychoactive substances or the presence of an eating disorder, however no study has compared these two types of patients with respect t...
Article
Aim: Poppers have become legal in France since June 2013. Is their liberalisation associated with an increase of severe side effects observed? Methods: To identify elevated methaemoglobinaemia related to poppers abuse, we reviewed all methaemoglobin concentrations measured in Nantes university hospital, during 12 months. Results: Methaemoglobi...
Article
Full-text available
Impulse control disorders (ICDs) are a well-known adverse effect of dopamine agonists (DAAs). This critical review aims to summarize data on the prevalence and factors associated with the development of an ICD simultaneous to DAA use. A search of two electronic databases was completed from inception to July 2017. The search terms were medical subje...
Article
We assumed that, as in the case of addiction disorders, former cult members exhibit vulnerability and protective factors for cult commitment and membership. Thus, the aim of our study was to identify vulnerability factors that are involved in the commitment and in the retention in the group, as well as protective factors that are involved in the de...
Article
Introduction. In France, an addictovigilance network is responsible for evaluating drug dependence, by drawing on pharmacoepidemiological studies, clinical studies and by assessing healthcare professionals’ reports on problematic consumption. Methods. The aim of this study was to determine whether zolpidem and zopiclone have different dependence pr...
Article
Full-text available
Purpose: Over the last few years, disordered eating in athletes has received increasing attention. According to several studies, athletes could be more vulnerable to disordered eating and some characteristics specific to the athletic community could be in favour of an increased risk of poor body image and disturbed eating habits in athletes. Howev...
Article
Introduction Les patients souffrant de syndrome drepanocytaire majeur (SDM) sont particulierement exposes a des douleurs aigues liees aux crises vaso-occlusives, de facon parfois repetee et imprevisible. Il existe dans cette population un risque de pseudo-addiction, d’abus et de dependance aux antalgiques peu evalue. L’objectif de l’etude Phedre es...
Article
Introduction L’adolescence représente une période charnière du développement cérébral avec une vulnérabilité accrue à la prise de risque. Le nombre de déclarations reçues au CEIP-A de Nantes rapportant des conséquences graves avérées ou potentielles liées à des consommations occasionnelles de substances psychoactives (SPA) chez des sujets de moins...
Article
Full-text available
Background Gamma-hydroxybutyrate (GHB) is a synthetic drug increasingly used by consumers of psychoactive substances. The sought after psychoactive effects of GHB have resulted in an increase in recreational use in Europe. GHB is considered to have a high dependence potential, and abrupt discontinuation after long-term use can result in a severe wi...
Article
Full-text available
Concerns about body shape and weight are core diagnostic criteria for eating disorders although intensity varies between patients. Few studies have focused on the clinical differences relative to the intensity of these concerns. Nonetheless, they might have a prognostic value. This study was aimed at identifying the characteristics associated with...
Data
Diagnostic criteria for Anorexia Nervosa and Bulimia Nervosa according to American Psychiatric Association. Diagnostic and statistical manual of mental health disorders: DSM-5 5th ed. Washington DC: American Psychiatric Publishing; 2013. (DOC)
Article
Objectifs En France, le réseau des Centres d’évaluation et d’information sur la pharmacodépendance-addictovigilance” (CEIP-A) est responsable de la collecte et de l’évaluation des notifications rapportant une dépendance à des substances psychoactives médicamenteuses ou non. Ces notifications sont évaluées à l’aide d’un score qui permet d’évaluer le...
Article
Full-text available
Aims: The French health authority (ANSM) is responsible for monitoring medicinal and other drug dependencies. To support these activities, the ANSM manages a network of 13 drug dependence evaluation and information centres (Centres d'Evaluation et d'Information sur la Pharmacodépendance - Addictovigilance - CEIP-A) throughout France. In 2006, the...
Article
Background: Methadone and buprenorphine are the two opiate maintenance treatments (OMT) available in France. According to the good clinical practices, a full clinical and biological assessment is required before deciding to initiate or renew an OMT. For methadone, this assessment includes psychoactive drug consumption investigation, through an ini...
Article
Full-text available
Background: The use of analgesics can lead to cases of drug abuse and dependence. It can also cause pseudo-addiction in patients suffering from pain. What is the actual situation in patients suffering from severe sickle-cell disease, exposed to acute pain during vaso-occlusive crises? Evaluation of the use of analgesics, on the basis of Diagnostic...
Article
Introduction Les troubles du comportement alimentaire (TCA) sont des pathologies fréquentes qui touchent principalement les femmes et dont le pronostic reste réservé. Les patientes souffrant de TCA sont beaucoup plus préoccupées par leur image corporelle et leur poids que le reste de la population [1]. De surcroît, les préoccupations corporelles se...
Article
L’objectif de l’étude était d’évaluer si l’attachement insécure était associé à des symptômes plus sévères dans l’anorexie mentale.
Article
Introduction En France, le réseau des Centres d’évaluation et d’information sur la pharmacodépendance (CEIP) a pour mission d’évaluer le potentiel de dépendance des médicaments et substances. Ils disposent pour cela d’un outil permettant de recueillir les notifications des cas d’abus et de dépendance émanant des professionnels de santé. Un score, r...
Article
Abstract In 2004, the health authorities modified the summary of zolpidem characteristics. The present paper aims at showing that, in spite of this modification, zolpidem remains considered as a drug associated with problematic use, as the official system providing information on abuse and/or dependence potential of drugs informs us. Methods The au...
Article
Full-text available
Eating disorders are complex troubles with a psychological, behavioural or physical expression. Care must therefore be both diverse and organised in order to help the patient to recover an healthy development without these disorders often symptoms of a failure of adolescence. Authors describe the different type of care generally provided, recalling...

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Project (1)
Project
EMONO effect in pediatrics dental care