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22
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Introduction
Publications
Publications (22)
Despite efforts by the adult generation to stem the rise of global warming, the planet is getting hotter every year. The present article analyzes, within the framework of social-cognitive theory, highly resourceful youth conducting environmental programs that curtail heat-trapping gases and protect various ecological supports of life. The children'...
Background
Childhood and adolescent obesity is associated with insulin resistance, abnormal glucose metabolism, hypertension, dyslipidemia, inflammation, liver disease, and compromised vascular function. The purpose of this pilot study was to determine the prevalence of cardiometabolic risk factor abnormalities and metabolic syndrome (MetS) in a sa...
If young people have the opportunity to connect with the natural world, they often become greatly motivated to save the things they come to love. Their natural empathy for the animals and, by extension, the ecosystems they depend upon can make youth wonderful advocates for wildlife and their habitat—and places where they themselves can go to experi...
The nature and contribution of different pregnancy-related complications to future cardiovascular disease (CVD) and its risk factors and the mechanisms underlying these associations remain unclear.
We studied associations of pregnancy diabetes mellitus, hypertensive disorders of pregnancy, preterm delivery, and size for gestational age with calcula...
Lynne Cherry Brandwein Lecture March 2010 National Science Teachers Association (NSTA) Conference, Philadelphia, PA. Young
Voices on Climate Change: Inspired and Empowered Youth Tackle Climate Science and Find Climate Solutions. As a child, Lynne
Cherry was profoundly connected to the natural world and a special place. She watched the destruction o...
The aim of this study was to determine whether simvastatin would protect against inflammation-induced aortic stiffening and endothelial dysfunction.
Aortic pulse wave velocity (aPWV) and flow-mediated dilatation (FMD) were assessed three times, at baseline, after a 14 day administration of simvastatin or placebo and 8 h after Salmonella typhi vacci...
To examine the prospective associations between body mass index (BMI), waist circumference, and fat mass in childhood and cardiovascular risk factors at age 15-16.
Prospective cohort study.
Avon Longitudinal Study of Parents and Children.
5235 children aged 9-12 at start of study. Main exposures BMI, waist circumference, and fat mass determined by...
Adiponectin is an anti-inflammatory and potentially antiatherogenic molecule. Some recent reports suggest that tumour necrosis factor alpha (TNFalpha) blockade therapy increases circulating adiponectin levels, but data are sparse and inconsistent.
Data from a double-blind placebo controlled study of onercept in 126 patients with psoriatic arthritis...
Offspring and maternal birthweight are inversely associated with maternal cardiovascular disease. However, whether established or putative novel cardiovascular risk factors including vascular and metabolic function are disrupted in women who delivered small for gestational age (SGA) offspring is unknown.
Case control study with analysis of inflamma...
Adiponectin levels appear weakly linked to incident vascular disease, but the high molecular weight (HMW) fraction may be more relevant.
Our objective was to test whether HMW adiponectin, the key biologically active fraction, is linked to incident coronary heart disease (CHD) events. DESIGN, PARTICIPANTS, AND MAIN OUTCOME MEASURES: We assessed the...
To examine the association of insulin-like-growth factor 1 (IGF-1) with coronary heart disease (CHD) in women.
Prospective (4 year) case-control study nested within the British Women's Heart and Health Study. With 167 cases and 333 controls. Serum IGF-1 concentrations (on serum stored at -80 degrees C for a median of 4 years) were determined using...
Adiponectin is considered by many to be part of the 'common soil' linking type 2 diabetes and coronary heart disease (CHD). We examined the relationship between adiponectin and insulin resistance, metabolic, inflammatory and haemostatic risk factors and hepatic function.
The study was carried out in 3640 non-diabetic men aged 60-79 years drawn from...
The aim was to assess the relationship between adipokines, including interleukin (IL)-6, leptin, and adiponectin, with development of type 2 diabetes and assess the role of obesity and insulin resistance in these relationships.
We conducted a prospective study of 3,599 nondiabetic men aged 60-79 years and followed up for a mean period of 5 years, d...
We thank Dr Pischon and colleagues for their interest in our work.1 We have reported the largest single prospective population-based study of adiponectin levels and coronary heart disease thus far, reinforced by a meta-analysis of 6 previous studies totaling 1313 incident cases.1 Overall, the adjusted risk ratio for coronary heart disease was 0.84...
To conduct a robust, double-blind, placebo-controlled study examining the effects of tumor necrosis factor (TNF) modulation on concentrations of traditional and novel cardiovascular disease risk factors in patients with an inflammatory condition.
In this double-blind study, 127 patients with psoriatic arthritis (PsA) and active psoriasis were rando...
There is uncertainty about the association between circulating concentrations of adiponectin and coronary heart disease (CHD) risk. We report new data from a prospective study in the context of a meta-analysis of previously published prospective studies.
We measured baseline adiponectin levels in stored serum samples of 589 men with fatal CHD or no...
Men with AS (ankylosing spondylitis) are at elevated risk for CHD (coronary heart disease) but information on risk factors is sparse. We compared a range of conventional and novel risk factors in men with AS in comparison with healthy controls and, in particular, determined the influence of systemic inflammation. Twenty-seven men with confirmed AS...
Preeclampsia is characterized by hypertension, dyslipidemia, and increased systemic inflammatory response and has been associated with an increased maternal risk of cardiovascular disease later in life. Low-grade chronic inflammation is a risk factor for cardiovascular disease. This study examined changes in inflammatory markers prospectively durin...
Scientists and kids explore climate change together. The book is a non-scary, action-oriented, and inspiring look at how scientists do their work, what they are discovering about global warming, and how kids are already learning about this through Citizen Science. Kids can make a difference! A film project: "Children's Voices on Climate Change" is...